The Oncosearch | Oncotarget

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

Allison Makovec, John T. Phoenix, Hannah E. Bergom, Ella Boytim, Ava P. Gustafson, Aiden Deacon, Sydney Tape, Atef Ali, Megan Ludwig, Samuel P. Pitzen, David Moline, Camden Richter, Hudson Longie, Mei-Chi Su, Sampreeti Jena, Pornlada Likasitwatanakul, Justin M. Drake, R. Stephanie Huang, William C. Hahn, Jonathan P. Rennhack, Scott M. Dehm, Steven Kregel, Emmanuel S. Antonarakis, Justin Hwang

Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 59-73

Keywords: prostate cancer, CREB5, basal-like, stem cell-like, AP-1 transcription factors

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

Jacob Haagsma, Yudith Ramos Valdes, Xuejin Ou, Rasheduzzaman Rashu, S.M. Mansour Haeryfar, Jim Petrik, Trevor G. Shepherd

Published Sep 16, 2025 · Vol. 16, No. 1 · pp. 697-718

Keywords: high-grade serous ovarian carcinoma, orthotopic models, inflammation, microenvironment

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

Andrea Gunnell, Scott T. Kimber, Richard Houlston, Martin Kaiser

Published Mar 16, 2025 · Vol. 16, No. 1 · pp. 220-229

Keywords: myeloma, NSD2, t(4;14), CD38, plasma cell

Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC Research Paper

Samuel Silva, Juliana C. Sousa, Cleto Nogueira, Raquel Feijo, Francisco Martins Neto, Laura Cardoso Marinho, Guilherme Sousa, Valeria Denninghoff, Fabio Tavora

Published Oct 4, 2024 · Vol. 15, No. 1 · pp. 750-763

Keywords: DLL3, pathology, biomarkers, qupath, small cell carcinoma

Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival Research Paper

Saif Zaman, Fred S. Gorelick, Andrea Chrobrutskiy, Boris I. Chobrutskiy, Gary V. Desir, George Blanck

Published Jul 20, 2024 · Vol. 15, No. 1 · pp. 550-561

Keywords: RNLS, melanoma, T-cell receptor CDR3s, chemical complementarity

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Caroline Naomi Valdez, Gabriela Athziri Sánchez-Zuno, Lais Osmani, Wael Ibrahim, Anjela Galan, Antonietta Bacchiocchi, Ruth Halaban, Rajan P. Kulkarni, Insoo Kang, Richard Bucala, Thuy Tran

Published Jul 15, 2024 · Vol. 15, No. 1 · pp. 507-520

Keywords: MIF, DDT, melanoma, immune checkpoint inhibition, cancer transcriptomics

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma Research Paper

Kazuhiro Kitajima, Kozo Kuribayashi, Toshiyuki Minami, Hiroyuki Yokoyama, Akifumi Nakamura, Masaki Hashimoto, Takashi Kijima, Seiki Hasegawa, Hayato Kaida, Koichiro Yamakado

Published Jun 11, 2024 · Vol. 15, No. 1 · pp. 408-417

Keywords: mesothelioma, immunotherapy, FDG (fluorodeoxyglucose), PET-CT (positron emission tomography-computed tomography), immunotherapy-modified PERCIST (positron emission tomography response criteria in solid tumors)

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Lulzim Shkreta, Johanne Toutant, Aurélie Delannoy, David Durantel, Anna Salvetti, Sophie Ehresmann, Martin Sauvageau, Julien A. Delbrouck, Alice Gravel-Trudeau, Christian Comeau, Caroline Huard, Jasmin Coulombe-Huntington, Mike Tyers, David Grierson, Pierre-Luc Boudreault, Benoit Chabot

Published May 9, 2024 · Vol. 15, No. 1 · pp. 313-325

Keywords: CLK kinases inhibitors, EMT, antiviral immune response, microtubules, metastasis

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas Research Paper

Thomas M. Cardillo, Maria B. Zalath, Roberto Arrojo, Robert M. Sharkey, Serengulam V. Govindan, Chien-Hsing Chang, David M. Goldenberg

Published Jan 30, 2024 · Vol. 15, No. 1 · pp. 144-158

Keywords: sacituzumab govitecan, Trop-2, SN-38, carboplatin, cisplatin

The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies Research Paper

Fusheng Zhou, Lili Tang, Siyuan Le, Mei Ge, Dragan Cicic, Fubo Xie, Jinmin Ren, Jiong Lan, Qiang Lu

Published Dec 9, 2023 · Vol. 14, No. 1 · pp. 997-1008

Keywords: GFH009, CDK9, cancer, leukemia, cell cycle

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior Research Paper

Fang Cheng, Victor Chérouvrier Hansson, Grigorios Georgolopoulos, Katrin Mani

Published Mar 13, 2023 · Vol. 14, No. 1 · pp. 219-235

Keywords: Glypican-1, TCGA, bladder carcinoma, hepatocellular carcinoma, glioma

PRRX1 induces epithelial-mesenchymal transition in oesophageal cancer Research Paper

Jinbao Guo, Ming Du, Bin Wang, Li Zhong, Zhongxue Fu, Jinlai Wei

Published Mar 10, 2023

Keywords: PRRX1, oesophageal cancer, epithelial–mesenchymal transition, cancer metastasis

Impact of Covid-19 on the management of patients with metastatic melanoma Research Paper

Michèle Welti, Phil F. Cheng, Joanna Mangana, Mitchell P. Levesque, Reinhard Dummer, Laurence Imhof

Published Dec 14, 2022 · Vol. 13, No. 1 · pp. 1370-1379

Keywords: metastatic melanoma, Covid-19, Sars-CoV-2, immunotherapy, targeted therapy

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

Hongyan Yuan, Lu Jin, Handan Xiang, Anannya Bhattacharya, Philip E. Brandish, Gretchen Baltus, Alexander Tong, Changyan Zhou, Robert I. Glazer

Published Dec 10, 2022 · Vol. 13, No. 1 · pp. 1350-1358

Keywords: PD-1, NeuT, Wnt, macrophages, mammary tumorigenesis

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Yehia I. Mohamed, Dan G. Duda, Muhammad O. Awiwi, Sunyoung S. Lee, Lina Altameemi, Lianchun Xiao, Jeffrey S. Morris, Robert A. Wolff, Khaled M. Elsayes, Rikita I. Hatia, Aliya Qayyum, Shadi M. Chamseddine, Asif Rashid, James C. Yao, Armeen Mahvash, Manal M. Hassan, Hesham M. Amin, Ahmed Omar Kaseb

Published Nov 26, 2022 · Vol. 13, No. 1 · pp. 1314-1321

Keywords: growth hormone, hepatocellular carcinoma, immunotherapy, atezolizumab, bevacizumab

Treasures from trash in cancer research Research Perspective

Fabiano Cordeiro Moreira, Dionison Pereira Sarquis, Jorge Estefano Santana de Souza, Daniel de Souza Avelar, Taíssa Maria Thomaz Araújo, André Salim Khayat, Sidney Emanuel Batista dos Santos, Paulo Pimentel de Assumpção

Published Nov 4, 2022 · Vol. 13, No. 1 · pp. 1246-1257

Keywords: cancer metagenomics, cancer sncRNA expression, RNA-Seq variant calling

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Jun Gong, Michelle Guan, Haesoo Kim, Natalie Moshayedi, Sejal Mehta, Galen Cook-Wiens, Brent K. Larson, Jenny Zhou, Rishi Patel, Isaac Lapite, Veronica R. Placencio-Hickok, Richard Tuli, Ronald B. Natale, Andrew E. Hendifar

Published Oct 25, 2022 · Vol. 13, No. 1 · pp. 1202-1214

Keywords: hyaluronan, hyaluronic acid, biomarker, prognostic, predictive

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells Research Paper

Ida Steiro, Esten N. Vandsemb, Samah Elsaadi, Kristine Misund, Anne-Marit Sponaas, Magne Børset, Pegah Abdollahi, Tobias S. Slørdahl

Published Oct 15, 2022 · Vol. 13, No. 1 · pp. 1175-1186

Keywords: matriptase, multiple myeloma, tumor suppressor, migration, Src

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Christine Sanders, Jan-Frederic Lau, Dimo Dietrich, Sebastian Strieth, Peter Brossart, Glen Kristiansen

Published Oct 14, 2022 · Vol. 13, No. 1 · pp. 1166-1173

Keywords: Nectin-4, enfortumab-vedotin, HNSCC, p16

Predicting cancer immunotherapy response from gut microbiomes using machine learning models Research Paper

Hai Liang, Jay-Hyun Jo, Zhiwei Zhang, Margaret A. MacGibeny, Jungmin Han, Diana M. Proctor, Monica E. Taylor, You Che, Paul Juneau, Andrea B. Apolo, John A. McCulloch, Diwakar Davar, Hassane M. Zarour, Amiran K. Dzutsev, Isaac Brownell, Giorgio Trinchieri, James L. Gulley, Heidi H. Kong

Published Jun 28, 2022 · Vol. 13, No. 1 · pp. 876-889

Keywords: gut microbiome, immunotherapy, 16S rRNA, machine learning, metagenomics

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CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC Research Paper

Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival Research Paper

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma Research Paper

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas Research Paper

The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies Research Paper

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior Research Paper

PRRX1 induces epithelial-mesenchymal transition in oesophageal cancer Research Paper

Impact of Covid-19 on the management of patients with metastatic melanoma Research Paper

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Treasures from trash in cancer research Research Perspective

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells Research Paper

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Predicting cancer immunotherapy response from gut microbiomes using machine learning models Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer Research Paper

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC Research Paper

Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival Research Paper

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma Research Paper

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas Research Paper

The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies Research Paper

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior Research Paper

PRRX1 induces epithelial-mesenchymal transition in oesophageal cancer Research Paper

Impact of Covid-19 on the management of patients with metastatic melanoma Research Paper

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Treasures from trash in cancer research Research Perspective

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells Research Paper

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Predicting cancer immunotherapy response from gut microbiomes using machine learning models Research Paper