The Oncosearch | Oncotarget

SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells Research Paper

Wenjun Zhang, Haixia Wu, Meng Yang, Shiguang Ye, Liang Li, Hong Zhang, Jiong Hu, Xuguang Wang, Jun Xu, Aibin Liang

Published Dec 3, 2015 · Vol. 7, No. 12 · pp. 13538-13550

NF-Y activates genes of metabolic pathways altered in cancer cells Research Paper

Paolo Benatti, Maria Luisa Chiaramonte, Mariangela Lorenzo, John A. Hartley, Daniel Hochhauser, Nerina Gnesutta, Roberto Mantovani, Carol Imbriano, Diletta Dolfini

Published Dec 3, 2015 · Vol. 7, No. 2 · pp. 1633-1650

HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer Research Paper

Naoki Takegawa, Kimio Yonesaka, Kazuko Sakai, Hiroto Ueda, Satomi Watanabe, Yoshikane Nonagase, Tatsuya Okuno, Masayuki Takeda, Osamu Maenishi, Junji Tsurutani, Taroh Satoh, Isamu Okamoto, Kazuto Nishio, Takao Tamura, Kazuhiko Nakagawa

Published Dec 2, 2015 · Vol. 7, No. 3 · pp. 3453-3460

Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response Research Paper

Arun Pradhan, Vladimir Ustiyan, Yufang Zhang, Tanya V. Kalin, Vladimir V. Kalinichenko

Published Nov 28, 2015 · Vol. 7, No. 2 · pp. 1912-1926

Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1 Research Paper

Diana G. Wright, Claire Marchal, Kimson Hoang, John A. Ankney, Stephanie T. Nguyen, Amanda W. Rushing, Nicholas Polakowski, Benoit Miotto, Isabelle Lemasson

Published Nov 28, 2015 · Vol. 7, No. 2 · pp. 1687-1706

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs Research Paper

Vanesa Nogales, William C. Reinhold, Sudhir Varma, Anna Martinez-Cardus, Catia Moutinho, Sebastian Moran, Holger Heyn, Ana Sebio, Agusti Barnadas, Yves Pommier, Manel Esteller

Published Nov 27, 2015 · Vol. 7, No. 3 · pp. 3084-3097

Mitochondrial retrograde signaling inhibits the survival during prolong S/G2 arrest in Saccharomyces cerevisiae Priority Research Paper

Anna N. Zyrina, Maksim I. Sorokin, Sviatoslav S. Sokolov, Dmitry A. Knorre, Fedor F. Severin

Published Nov 27, 2015 · Vol. 6, No. 42 · pp. 44084-44094

Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation Research Paper

Li Xie, Xingguo Song, Wei Guo, Xingwu Wang, Ling Wei, Yang Li, Liyan Lv, Weijun Wang, Thomas C. Chen, Xianrang Song

Published Nov 27, 2015 · Vol. 7, No. 2 · pp. 1651-1662

BAG3 elevation inhibits cell proliferation via direct interaction with G6PD in hepatocellular carcinomas Research Paper

De-Hui Kong, Si Li, Zhen-Xian Du, Chuan Liu, Bao-Qin Liu, Chao Li, Zhi-Hong Zong, Hua-Qin Wang

Published Nov 26, 2015 · Vol. 7, No. 1 · pp. 700-711

Implications of a peroxisome proliferator-activated receptor alpha (PPARÎ±) ligand clofibrate in breast cancer Research Paper

Karthic Chandran, Sudeshna Goswami, Neelam Sharma-Walia

Published Nov 26, 2015 · Vol. 7, No. 13 · pp. 15577-15599

miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response Research Paper

Alessandra Cataldo, Douglas G. Cheung, Andrea Balsari, Elda Tagliabue, Vincenzo Coppola, Marilena V. Iorio, Dario Palmieri, Carlo M. Croce

Published Nov 25, 2015 · Vol. 7, No. 1 · pp. 786-797

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Namrata Rastogi, Shivali Duggal, Shailendra Kumar Singh, Konica Porwal, Vikas Kumar Srivastava, Rakesh Maurya, Madan L.B. Bhatt, Durga Prasad Mishra

Published Nov 25, 2015 · Vol. 6, No. 41 · pp. 43310-43325

The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells Research Paper

Christian Mayr, Andrej Wagner, Magdalena Loeffelberger, Daniela Bruckner, Martin Jakab, Frieder Berr, Pietro Di Fazio, Matthias Ocker, Daniel Neureiter, Martin Pichler, Tobias Kiesslich

Published Nov 24, 2015 · Vol. 7, No. 1 · pp. 745-758

Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations Research Paper

Shaohua Peng, Banibrata Sen, Tuhina Mazumdar, Lauren A. Byers, Lixia Diao, Jing Wang, Pan Tong, Uma Giri, John V. Heymach, Humam N. Kadara, Faye M. Johnson

Published Nov 23, 2015 · Vol. 7, No. 1 · pp. 565-579

A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase Research Paper

Nandini Sakurikar, Ruth Thompson, Ryan Montano, Alan Eastman

Published Nov 22, 2015 · Vol. 7, No. 2 · pp. 1380-1394

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex Priority Research Paper

Martin Fischer, Marianne Quaas, Annina Nickel, Kurt Engeland

Published Nov 22, 2015 · Vol. 6, No. 39 · pp. 41402-41417

Epigenetic repression of PDZ-LIM domain-containing protein 2 promotes ovarian cancer via NOS2-derived nitric oxide signaling Research Paper

Linjie Zhao, Chuan Yu, Shengtao Zhou, Wayne Bond Lau, Bonnie Lau, Zhongyue Luo, Qiao Lin, Huiliang Yang, Yu Xuan, Tao Yi, Xia Zhao, Yuquan Wei

Published Nov 22, 2015 · Vol. 7, No. 2 · pp. 1408-1420

miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer Research Paper

Xiaohui Tan, Yebo Fu, Liang Chen, Woojin Lee, Yinglei Lai, Katayoon Rezaei, Sana Tabbara, Patricia Latham, Christine B. Teal, Yan-Gao Man, Robert S. Siegel, Rachel F. Brem, Sidney W. Fu

Published Nov 18, 2015 · Vol. 7, No. 1 · pp. 293-307

Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells Research Paper

Maciej Kliszczak, Hana Sedlackova, Ganesha P. Pitchai, Werner W. Streicher, Lumir Krejci, Ian D. Hickson

Published Nov 17, 2015 · Vol. 6, No. 38 · pp. 40464-40479

Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein Priority Research Paper

Yanxiao Zhang, Jingcheng Yu, Chee Lee, Bin Xu, Maureen A. Sartor, Ronald J. Koenig

Published Nov 16, 2015 · Vol. 6, No. 38 · pp. 40418-40432

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SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells Research Paper

NF-Y activates genes of metabolic pathways altered in cancer cells Research Paper

HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer Research Paper

Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response Research Paper

Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1 Research Paper

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs Research Paper

Mitochondrial retrograde signaling inhibits the survival during prolong S/G2 arrest in Saccharomyces cerevisiae Priority Research Paper

Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation Research Paper

BAG3 elevation inhibits cell proliferation via direct interaction with G6PD in hepatocellular carcinomas Research Paper

Implications of a peroxisome proliferator-activated receptor alpha (PPARÎ±) ligand clofibrate in breast cancer Research Paper

miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response Research Paper

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells Research Paper

Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations Research Paper

A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase Research Paper

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex Priority Research Paper

Epigenetic repression of PDZ-LIM domain-containing protein 2 promotes ovarian cancer via NOS2-derived nitric oxide signaling Research Paper

miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer Research Paper

Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells Research Paper

Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells Research Paper

NF-Y activates genes of metabolic pathways altered in cancer cells Research Paper

HER2 genomic amplification in circulating tumor DNA from patients with cetuximab-resistant colorectal cancer Research Paper

Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response Research Paper

Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1 Research Paper

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs Research Paper

Mitochondrial retrograde signaling inhibits the survival during prolong S/G2 arrest in Saccharomyces cerevisiae Priority Research Paper

Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation Research Paper

BAG3 elevation inhibits cell proliferation via direct interaction with G6PD in hepatocellular carcinomas Research Paper

Implications of a peroxisome proliferator-activated receptor alpha (PPARÎ±) ligand clofibrate in breast cancer Research Paper

miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response Research Paper

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells Research Paper

Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations Research Paper

A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase Research Paper

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex Priority Research Paper

Epigenetic repression of PDZ-LIM domain-containing protein 2 promotes ovarian cancer via NOS2-derived nitric oxide signaling Research Paper

miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer Research Paper

Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells Research Paper

Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein Priority Research Paper