The Oncosearch | Oncotarget

WWOX modulates the ATR-mediated DNA damage checkpoint response Research Paper

Mohammad Abu-Odeh, Nyla A. Hereema, Rami I. Aqeilan

Published Dec 12, 2015 · Vol. 7, No. 4 · pp. 4344-4355

Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations Research Paper

Susanne Lorenz, Tale BarÃ¸y, Jinchang Sun, Torfinn Nome, Daniel VodÃ¡k, Jan-Christian Bryne, Anne-Mari HÃ¥kelien, Lynnette Fernandez-Cuesta, Birte MÃ¶hlendick, Harald Rieder, Karoly Szuhai, Olga Zaikova, Terje C. Ahlquist, Gard O. S. Thomassen, Rolf I. Skotheim, Ragnhild A. Lothe, Patrick S. Tarpey, Peter Campbell, Adrienne Flanagan, Ola Myklebost, Leonardo A. Meza-Zepeda

Published Dec 11, 2015 · Vol. 7, No. 5 · pp. 5273-5288

UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation Research Paper

Cheng Du, Hong Wu, Roger P. Leng

Published Dec 10, 2015 · Vol. 7, No. 3 · pp. 2823-2836

Epigenetic modification of TLR4 promotes activation of NF-ÎºB by regulating methyl-CpG-binding domain protein 2 and Sp1 in gastric cancer Research Paper

Tae Woo Kim, Seon-Jin Lee, Byung Moo Oh, Heesoo Lee, Tae Gi Uhm, Jeong-Ki Min, Young-Jun Park, Suk Ran Yoon, Bo-Yeon Kim, Jong Wan Kim, Yong-Kyung Choe, Hee Gu Lee

Published Dec 10, 2015 · Vol. 7, No. 4 · pp. 4195-4209

A novel PAD4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute promyelocytic leukemia cells into granulocytic cells Research Paper

Guanhua Song, Lulu Shi, Yuqi Guo, Linchang Yu, Lin Wang, Xiaoyu Zhang, Lianlian Li, Yang Han, Xia Ren, Qiang Guo, Kehong Bi, Guosheng Jiang

Published Dec 10, 2015 · Vol. 7, No. 3 · pp. 3144-3157

Epigenetic effects of RRx-001: a possible unifying mechanism of anticancer activity Priority Research Paper

Hongjuan Zhao, Shoucheng Ning, Jan Scicinski, Bryan Oronsky, Susan J. Knox, Donna M. Peehl

Published Dec 9, 2015 · Vol. 6, No. 41 · pp. 43172-43181

The CNGRC-GG-_D(KLAKLAK)₂ peptide induces a caspase-independent, Ca²⁺-dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13 Research Paper

Sandrine Bouchet, Ruoping Tang, Fanny Fava, Ollivier Legrand, Brigitte Bauvois

Published Dec 9, 2015 · Vol. 7, No. 15 · pp. 19445-19467

Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence Research Paper

Sabine Taschner-Mandl, Magdalena Schwarz, Johanna Blaha, Maximilian Kauer, Florian Kromp, Nelli Frank, Fikret Rifatbegovic, Tamara Weiss, Ruth Ladenstein, Martin Hohenegger, Inge M. Ambros, Peter F. Ambros

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3571-3586

Towards understanding the breast cancer epigenome: a comparison of genome-wide DNA methylation and gene expression data Research Paper

Sandeep K. Singhal, Nawaid Usmani, Stefan Michiels, Otto Metzger-Filho, Kamal S. Saini, Olga Kovalchuk, Matthew Parliament

Published Dec 8, 2015 · Vol. 7, No. 3 · pp. 3002-3017

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

Gerald Goh, Trent Walradt, Vladimir Markarov, Astrid Blom, Nadeem Riaz, Ryan Doumani, Krista Stafstrom, Ata Moshiri, Lola Yelistratova, Jonathan Levinsohn, Timothy A. Chan, Paul Nghiem, Richard P. Lifton, Jaehyuk Choi

Published Dec 7, 2015 · Vol. 7, No. 3 · pp. 3403-3415

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma Research Paper

Anneleen Decock, MatÃ© Ongenaert, Robrecht Cannoodt, Kimberly Verniers, Bram De Wilde, GeneviÃ¨ve Laureys, Nadine Van Roy, Ana P. Berbegall, Julie Bienertova-Vasku, Nick Bown, Nathalie ClÃ©ment, ValÃ©rie Combaret, Michelle Haber, Claire Hoyoux, Jayne Murray, Rosa Noguera, Gaelle Pierron, Gudrun Schleiermacher, Johannes H. Schulte, Ray L. Stallings, Deborah A. Tweddle, for the Childrenâ€™s Cancer and Leukaemi Group (CCLG), Katleen De Preter, Frank Speleman, Jo Vandesompele

Published Dec 6, 2015 · Vol. 7, No. 2 · pp. 1960-1972

Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma Research Paper

Rochelle L. Tiedemann, Ryan A. Hlady, Paul D. Hanavan, Douglas F. Lake, Raoul Tibes, Jeong-Heon Lee, Jeong-Hyeon Choi, Thai H. Ho, Keith D. Robertson

Published Dec 5, 2015 · Vol. 7, No. 2 · pp. 1927-1946

Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-ÎºB Priority Research Paper

Ying Hu, Wenjie Ge, Xingwen Wang, Gopinath Sutendra, Kunming Zhao, Zinaida DedeiÄ‡, Elizabeth A. Slee, Caroline Baer, Xin Lu

Published Dec 5, 2015 · Vol. 6, No. 40 · pp. 42478-42490

Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer Research Paper

Mariko Kikuchi, Keishi Yamashita, Mina Waraya, Naoko Minatani, Hideki Ushiku, Ken Kojo, Akira Ema, Yoshimasa Kosaka, Hiroshi Katoh, Norihiko Sengoku, Takumo Enomoto, Hirokazu Tanino, Masakazu Sawanobori, Masahiko Watanabe

Published Dec 5, 2015 · Vol. 7, No. 2 · pp. 1741-1753

ATR-Chk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer Research Paper

Ching-Chia Li, Juan-Cheng Yang, Mei-Chin Lu, Chia-Lin Lee, Chieh-Yu Peng, Wei-Yu Hsu, Yun-Hao Dai, Fang-Rong Chang, Da-Yong Zhang, Wen-Jeng Wu, Yang-Chang Wu

Published Dec 5, 2015 · Vol. 7, No. 2 · pp. 1947-1959

Genomic landscape of liposarcoma Priority Research Paper

Deepika Kanojia, Yasunobu Nagata, Manoj Garg, Dhong Hyun Lee, Aiko Sato, Kenichi Yoshida, Yusuke Sato, Masashi Sanada, Anand Mayakonda, Christoph Bartenhagen, Hans-Ulrich Klein, Ngan B. Doan, Jonathan W. Said, S. Mohith, Swetha Gunasekar, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Ola Myklebost, Henry Yang, Martin Dugas, Leonardo A. Meza-Zepeda, Allan W. Silberman, Charles Forscher, Jeffrey W. Tyner, Seishi Ogawa, H. Phillip Koeffler

Published Dec 4, 2015 · Vol. 6, No. 40 · pp. 42429-42444

Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk Research Paper

Ying Ye, Ling Xiao, Su-Juan Wang, Wei Yue, Qiao-Shan Yin, Meng-Yao Sun, Wei Xia, Zhi-Yi Shao, Hong Zhang

Published Dec 4, 2015 · Vol. 7, No. 4 · pp. 3921-3933

Hormone stimulation of androgen receptor mediates dynamic changes in DNA methylation patterns at regulatory elements Research Paper

Vineet K. Dhiman, Kristopher Attwood, Moray J. Campbell, Dominic J. Smiraglia

Published Dec 4, 2015 · Vol. 6, No. 40 · pp. 42575-42589

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Serguei A. Gordeev, Tatiana V. Bykova, Svetlana G. Zubova, Olga A. Bystrova, Marina G. Martynova, Valery A. Pospelov, Tatiana V. Pospelova

Published Dec 4, 2015 · Vol. 6, No. 42 · pp. 44905-44926

Molecular analyses reveal close similarities between small cell carcinoma of the ovary, hypercalcemic type and atypical teratoid/rhabdoid tumor Research Paper

Somayyeh Fahiminiya, Leora Witkowski, Javad Nadaf, Jian Carrot-Zhang, Catherine Goudie, Martin Hasselblatt, Pascal Johann, Marcel Kool, Ryan S. Lee, Tenzin Gayden, Charles W. M. Roberts, Jaclyn A. Biegel, Nada Jabado, Jacek Majewski, William D. Foulkes

Published Dec 4, 2015 · Vol. 7, No. 2 · pp. 1732-1740

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WWOX modulates the ATR-mediated DNA damage checkpoint response Research Paper

Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations Research Paper

UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation Research Paper

Epigenetic modification of TLR4 promotes activation of NF-ÎºB by regulating methyl-CpG-binding domain protein 2 and Sp1 in gastric cancer Research Paper

A novel PAD4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute promyelocytic leukemia cells into granulocytic cells Research Paper

Epigenetic effects of RRx-001: a possible unifying mechanism of anticancer activity Priority Research Paper

The CNGRC-GG-_D(KLAKLAK)₂ peptide induces a caspase-independent, Ca²⁺-dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13 Research Paper

Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence Research Paper

Towards understanding the breast cancer epigenome: a comparison of genome-wide DNA methylation and gene expression data Research Paper

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma Research Paper

Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma Research Paper

Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-ÎºB Priority Research Paper

Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer Research Paper

ATR-Chk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer Research Paper

Genomic landscape of liposarcoma Priority Research Paper

Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk Research Paper

Hormone stimulation of androgen receptor mediates dynamic changes in DNA methylation patterns at regulatory elements Research Paper

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Molecular analyses reveal close similarities between small cell carcinoma of the ovary, hypercalcemic type and atypical teratoid/rhabdoid tumor Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

WWOX modulates the ATR-mediated DNA damage checkpoint response Research Paper

Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations Research Paper

UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation Research Paper

Epigenetic modification of TLR4 promotes activation of NF-ÎºB by regulating methyl-CpG-binding domain protein 2 and Sp1 in gastric cancer Research Paper

A novel PAD4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute promyelocytic leukemia cells into granulocytic cells Research Paper

Epigenetic effects of RRx-001: a possible unifying mechanism of anticancer activity Priority Research Paper

The CNGRC-GG-D(KLAKLAK)2 peptide induces a caspase-independent, Ca2+-dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13 Research Paper

Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence Research Paper

Towards understanding the breast cancer epigenome: a comparison of genome-wide DNA methylation and gene expression data Research Paper

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma Research Paper

Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma Research Paper

Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-ÎºB Priority Research Paper

Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer Research Paper

ATR-Chk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer Research Paper

Genomic landscape of liposarcoma Priority Research Paper

Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk Research Paper

Hormone stimulation of androgen receptor mediates dynamic changes in DNA methylation patterns at regulatory elements Research Paper

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Molecular analyses reveal close similarities between small cell carcinoma of the ovary, hypercalcemic type and atypical teratoid/rhabdoid tumor Research Paper

The CNGRC-GG-_D(KLAKLAK)₂ peptide induces a caspase-independent, Ca²⁺-dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13 Research Paper