The Oncosearch | Oncotarget

Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia Research Paper

Hassan Ashktorab, Hamed Azimi, Sudhir Varma, Edward L. Lee, Adeyinka O. Laiyemo, Michael L. Nickerson, Hassan Brim

Published Apr 5, 2019 · Vol. 10, No. 27 · pp. 2607-2624

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

Ruth Halaban, Antonella Bacchiocchi, Robert Straub, Jian Cao, Mario Sznol, Deepak Narayan, Ahmed Allam, Michael Krauthammer, Tarek S. Mansour

Published Mar 19, 2019 · Vol. 10, No. 23 · pp. 2237-2251

Keywords: melanoma, SRC-family kinase inhibitors, MAPK, MITF

Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma Research Paper

Carla M.L. van Herpen, Sanjiv S. Agarwala, Axel Hauschild, Carola Berking, J. Thaddeus Beck, Dirk Schadendorf, Rob Jansen, Paola Queirolo, Paolo A. Ascierto, Christian U. Blank, Michael C. Heinrich, Rupam R. Pal, Adnan Derti, Victor Antona, Heidi Nauwelaerts, Angela Zubel, Reinhard Dummer

Published Mar 5, 2019 · Vol. 10, No. 19 · pp. 1850-1859

A targeted genomic alteration analysis predicts survival of melanoma patients under BRAF inhibitors Research Paper

Baptiste Louveau, Julie Delyon, Coralie Reger De Moura, Maxime Battistella, Fanelie Jouenne, Lisa Golmard, Aurelie Sadoux, Marie-Pierre Podgorniak, Ichrak Chami, Oren Marco, Julie Caramel, Stephane Dalle, Jean-Paul Feugeas, Nicolas Dumaz, Celeste Lebbe, Samia Mourah

Published Mar 1, 2019 · Vol. 10, No. 18 · pp. 1669-1687

CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition Research Paper

Jasmin B. Post, Nizar Hami, Alexander E.E. Mertens, Suraya Elfrink, Johannes L. Bos, Hugo J.G. Snippert

Published Feb 15, 2019 · Vol. 10, No. 14 · pp. 1440-1457

Recurrent hotspot SF3B1 mutations at codon 625 in vulvovaginal mucosal melanoma identified in a study of 27 Australian mucosal melanomas Research Paper

Camelia Quek, Robert V. Rawson, Peter M. Ferguson, Ping Shang, Ines Silva, Robyn P.M. Saw, Kerwin Shannon, John F. Thompson, Nicholas K. Hayward, Georgina V. Long, Graham J. Mann, Richard A. Scolyer, James S. Wilmott

Published Jan 29, 2019 · Vol. 10, No. 9 · pp. 930-941

Sustained response of three pediatric BRAF^V600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy Case Report

Stephanie A. Toll, Hung N. Tran, Jennifer Cotter, Alexander R. Judkins, Benita Tamrazi, Jaclyn A Biegel, Girish Dhall, Nathan J. Robison, Kaaren Waters, Palak Patel, Robert Cooper, Ashley S. Margol

Published Jan 11, 2019 · Vol. 10, No. 4 · pp. 551-557

Monitoring melanoma recurrence with circulating tumor DNA: a proof of concept from three case studies Research Paper

Ashleigh C. McEvoy, Michelle R. Pereira, Anna Reid, Robert Pearce, Lester Cowell, Zeyad Al-Ogaili, Muhammad A. Khattak, Michael Millward, Tarek M. Meniawy, Elin S. Gray, Melanie Ziman

Published Jan 4, 2019 · Vol. 10, No. 2 · pp. 113-122

Targeted therapies for advanced non-small cell lung cancer Review

Xiaojuan Ai, Xialing Guo, Jun Wang, Andreea L. Stancu, Patrick M.N. Joslin, Dianzheng Zhang, Shudong Zhu

Published Dec 25, 2018 · Vol. 9, No. 101 · pp. 37589-37607

Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas Research Paper

James L. Figarola, Jyotsana Singhal, Sharad Singhal, Jyotirmoy Kusari, Arthur Riggs

Published Dec 11, 2018 · Vol. 9, No. 97 · pp. 36945-36965

NEO412: A temozolomide analog with transdermal activity in melanoma in vitro and in vivo Research Paper

Steve Swenson, Catalina Silva-Hirschberg, Weijun Wang, Anupam Singh, Florence M. Hofman, Kristen L. Chen, Axel H. SchÃ¶nthal, Thomas C. Chen

Published Dec 11, 2018 · Vol. 9, No. 97 · pp. 37026-37041

Establishment of a novel cell line from a rare human duodenal poorly differentiated neuroendocrine carcinoma Research Paper

Kazuyoshi Yanagihara, Takanori Kubo, Keichiro Mihara, Takeshi Kuwata, Atsushi Ochiai, Toshio Seyama, Hiroshi Yokozaki

Published Nov 23, 2018 · Vol. 9, No. 92 · pp. 36503-36514

Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients Research Paper

Elodie Long-Mira, Marius Ilie, Emmanuel Chamorey, Florence Leduff-Blanc, Henri MontaudiÃ©, Virginie Tanga, Maryline AllÃ©gra, Virginie Lespinet-Fabre, Olivier Bordone, Christelle Bonnetaud, Renaud Schiappa, Catherine Butori, Coraline Bence, Jean-Philippe Lacour, VÃ©ronique Hofman, Paul Hofman

Published Nov 16, 2018 · Vol. 9, No. 90 · pp. 36238-36249

New insights in melanoma resistance to BRAF inhibitors: a role for microRNAs Editorial

Marta DÃaz-MartÃnez, LucÃa Benito-JardÃ³n, Joaquin TeixidÃ³

Published Oct 14, 2018 · Vol. 9, No. 83 · pp. 35374-35375

MEK/CDK4,6 co-targeting is effective in a subset of NRAS, BRAF and 'wild type' melanomas Research Paper

Christian Posch, Martina Sanlorenzo, Jeffrey Ma, Sarasa T. Kim, Mitchell Zekhtser, Susana Ortiz-Urda

Published Oct 9, 2018 · Vol. 9, No. 79 · pp. 34990-34995

The efficacy of re-challenge with BRAF inhibitors after previous progression to BRAF inhibitors in melanoma: A retrospective multicenter study Research Paper

Julia K. Tietze, Andrea Forschner, Carmen Loquai, Heidrun Mitzel-Rink, Lisa Zimmer, Frank Meiss, David Rafei-Shamsabadi, Jochen Utikal, Maike Bergmann, Friedegund Meier, Nicole Kreuzberg, Max Schlaak, Carsten Weishaupt, Claudia PfÃ¶hler, Mirjana Ziemer, Michael Fluck, Jessica Rainer, Markus V. Heppt, Carola Berking

Published Sep 28, 2018 · Vol. 9, No. 76 · pp. 34336-34346

Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach Research Paper

SofÃa del Carmen, JosÃ© MarÃa SayaguÃ©s, Oscar Bengoechea, MarÃa Fernanda Anduaga, Jose Antonio Alcazar, Ruth Gervas, Jacinto GarcÃa, Alberto Orfao, Luis MuÃ±oz Bellvis, MarÃa Eugenia Sarasquete, MarÃa del Mar Abad

Published Sep 28, 2018 · Vol. 9, No. 76 · pp. 34279-34288

A new B-Raf inhibitor combo for advanced melanoma Editorial

Marjam-Jeanette Barysch, Joanna Mangana, Reinhard Dummer

Published Sep 18, 2018 · Vol. 9, No. 77 · pp. 34457-34458

SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk Research Paper

Masashi Muramatsu, Shin Akakura, Lingqiu Gao, Jennifer Peresie, Benjamin Balderman, Irwin H. Gelman

Published Sep 11, 2018 · Vol. 9, No. 71 · pp. 33515-33527

Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer Research Paper

Yudong Wang, Zhijie Wang, Sarina Piha-Paul, Filip Janku, Vivek Subbiah, Naiyi Shi, Kenneth Hess, Russell Broaddus, Baoen Shan, Aung Naing, David Hong, Apostolia M. Tsimberidou, Daniel Karp, Charles Lu, Vali Papadimitrakopoulou, John Heymach, Funda Meric-Bernstam, Siqing Fu

Published Sep 7, 2018 · Vol. 9, No. 70 · pp. 33258-33270

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Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia Research Paper

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma Research Paper

A targeted genomic alteration analysis predicts survival of melanoma patients under BRAF inhibitors Research Paper

CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition Research Paper

Recurrent hotspot SF3B1 mutations at codon 625 in vulvovaginal mucosal melanoma identified in a study of 27 Australian mucosal melanomas Research Paper

Sustained response of three pediatric BRAF^V600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy Case Report

Monitoring melanoma recurrence with circulating tumor DNA: a proof of concept from three case studies Research Paper

Targeted therapies for advanced non-small cell lung cancer Review

Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas Research Paper

NEO412: A temozolomide analog with transdermal activity in melanoma in vitro and in vivo Research Paper

Establishment of a novel cell line from a rare human duodenal poorly differentiated neuroendocrine carcinoma Research Paper

Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients Research Paper

New insights in melanoma resistance to BRAF inhibitors: a role for microRNAs Editorial

MEK/CDK4,6 co-targeting is effective in a subset of NRAS, BRAF and 'wild type' melanomas Research Paper

The efficacy of re-challenge with BRAF inhibitors after previous progression to BRAF inhibitors in melanoma: A retrospective multicenter study Research Paper

Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach Research Paper

A new B-Raf inhibitor combo for advanced melanoma Editorial

SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk Research Paper

Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia Research Paper

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma Research Paper

A targeted genomic alteration analysis predicts survival of melanoma patients under BRAF inhibitors Research Paper

CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition Research Paper

Recurrent hotspot SF3B1 mutations at codon 625 in vulvovaginal mucosal melanoma identified in a study of 27 Australian mucosal melanomas Research Paper

Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy Case Report

Monitoring melanoma recurrence with circulating tumor DNA: a proof of concept from three case studies Research Paper

Targeted therapies for advanced non-small cell lung cancer Review

Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas Research Paper

NEO412: A temozolomide analog with transdermal activity in melanoma in vitro and in vivo Research Paper

Establishment of a novel cell line from a rare human duodenal poorly differentiated neuroendocrine carcinoma Research Paper

Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients Research Paper

New insights in melanoma resistance to BRAF inhibitors: a role for microRNAs Editorial

MEK/CDK4,6 co-targeting is effective in a subset of NRAS, BRAF and 'wild type' melanomas Research Paper

The efficacy of re-challenge with BRAF inhibitors after previous progression to BRAF inhibitors in melanoma: A retrospective multicenter study Research Paper

Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach Research Paper

A new B-Raf inhibitor combo for advanced melanoma Editorial

SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk Research Paper

Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer Research Paper

Sustained response of three pediatric BRAF^V600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy Case Report