The Oncosearch | Oncotarget

Distinct histone modifications denote early stress-induced drug tolerance in cancer Priority Research Paper

Abdullah Al Emran, Diego M. Marzese, Dinoop Ravindran Menon, Mitchell S. Stark, Joachim Torrano, Heinz Hammerlindl, Gao Zhang, Patricia Brafford, Matthew P. Salomon, Nellie Nelson, Sabrina Hammerlindl, Deepesh Gupta, Gordon B. Mills, Yiling Lu, Richard A. Sturm, Keith Flaherty, Dave S. B. Hoon, Brian Gabrielli, Meenhard Herlyn, Helmut Schaider

Published Dec 24, 2017 · Vol. 9, No. 9 · pp. 8206-8222

Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo Research Paper

Ho-Chung Chen, Jairo Sierra, Lumeng Jenny Yu, Robert Cerchio Jr., Brian A. Wall, James Goydos, Suzie Chen

Published Dec 23, 2017 · Vol. 9, No. 5 · pp. 5861-5875

Targeting the cyclin dependent kinase and retinoblastoma axis overcomes standard of care resistance in BRAF^V600E-mutant melanoma Research Paper

Antoneicka L. Harris, Samantha E. Lee, Louis K. Dawson, Laura A. Marlow, Brandy H. Edenfield, William F. Durham, Thomas J. Flotte, Michael Thompson, Daniel L. Small, Aidan J. Synnott, Svetomir N. Markovic, John A. Copland

Published Dec 23, 2017 · Vol. 9, No. 13 · pp. 10905-10919

Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer Research Paper

Hironori Aoki, Eiichiro Yamamoto, Akira Takasawa, Takeshi Niinuma, Hiro-O Yamano, Taku Harada, Hiro-O Matsushita, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada, Yoshihito Tanaka, Yuko Yoshida, Tomoyuki Aoyama, Makoto Eizuka, Akira Yorozu, Hiroshi Kitajima, Masahiro Kai, Norimasa Sawada, Tamotsu Sugai, Hiroshi Nakase, Hiromu Suzuki

Published Dec 20, 2017 · Vol. 9, No. 4 · pp. 4707-4721

Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement Research Paper

Reeta Kangas, Cristina Morsiani, Grazia Pizza, Catia Lanzarini, Pauliina Aukee, Jaakko Kaprio, Sarianna SipilÃ¤, Claudio Franceschi, Vuokko Kovanen, Eija K. Laakkonen, Miriam Capri

Published Dec 18, 2017 · Vol. 9, No. 2 · pp. 2279-2294

A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma Research Paper

Alessia Parascandolo, Mikko O. Laukkanen, Nancy De Rosa, Clara Ugolini, Maria Carmela Cantisani, Anna Maria Cirafici, Fulvio Basolo, Massimo Santoro, Maria Domenica Castellone

Published Dec 17, 2017 · Vol. 9, No. 4 · pp. 4496-4510

The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth Research Paper

Kimberley Hanson, Stephen D. Robinson, Karamallah Al-Yousuf, Adam E. Hendry, Darren W. Sexton, Victoria Sherwood, Grant N. Wheeler

Published Dec 17, 2017 · Vol. 9, No. 3 · pp. 3815-3829

Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma Research Paper

Renier Heijkants, Karen Willekens, Mark Schoonderwoerd, Amina Teunisse, Maaike Nieveen, Enrico Radaelli, Luuk Hawinkels, Jean-Christophe Marine, Aart Jochemsen

Published Dec 15, 2017 · Vol. 9, No. 5 · pp. 6174-6187

Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis Research Paper

Kuan-Fu Ding, Emanuel F. Petricoin, Darren Finlay, Hongwei Yin, William P.D. Hendricks, Chris Sereduk, Jeffrey Kiefer, Aleksandar Sekulic, Patricia M. LoRusso, Kristiina Vuori, Jeffrey M. Trent, Nicholas J. Schork

Published Dec 15, 2017 · Vol. 9, No. 4 · pp. 5044-5057

Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations Research Paper

William Bruno, Claudia Martinuzzi, Bruna Dalmasso, Virginia Andreotti, Lorenza Pastorino, Francesco Cabiddu, Marina Gualco, Francesco Spagnolo, Alberto Ballestrero, Paola Queirolo, Federica Grillo, Luca Mastracci, Paola Ghiorzo

Published Dec 14, 2017 · Vol. 9, No. 5 · pp. 5691-5702

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models Research Paper

Kei Kawaguchi, Kentaro Igarashi, Shukuan Li, Qinghong Han, Yuying Tan, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Takashi Murakami, Bartosz Chmielowski, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li5, Michiaki Unno, Fritz C. Eilber, Robert M. Hoffman

Published Dec 12, 2017 · Vol. 9, No. 1 · pp. 915-923

Targeting the PTTG1 oncogene impairs proliferation and invasiveness of melanoma cells sensitive or with acquired resistance to the BRAF inhibitor dabrafenib Research Paper

Simona Caporali, Ester Alvino, Pedro Miguel Lacal, Federica Ruffini, Lauretta Levati, Laura Bonmassar, Alessandro Scoppola, Paolo Marchetti, Simona Mastroeni, Gian Carlo Antonini Cappellini, Stefania Dâ€™Atri

Published Dec 9, 2017 · Vol. 8, No. 69 · pp. 113472-113493

LKB1 loss cooperating with BRAF V600E promotes melanoma cell invasion and migration by up-regulation MMP-2 via PI3K/Akt/mTOR pathway Research Paper

Weiming Zhang, Li Yin, Guoxin Song, Xue Han, Zhiqiang Yin, Dan Luo

Published Dec 5, 2017 · Vol. 8, No. 69 · pp. 113847-113857

Hypoxia-activated prodrug enhances therapeutic effect of sunitinib in melanoma Research Paper

Shujing Liu, Michael T. Tetzlaff, Tao Wang, Xiang Chen, Ruifeng Yang, Suresh M. Kumar, Adina Vultur, Pengxiang Li, James S. Martin, Meenhard Herlyn, Ravi Amaravadi, Bin Li, Xiaowei Xu

Published Dec 5, 2017 · Vol. 8, No. 70 · pp. 115140-115152

Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas Research Paper

Tomotaka Shimura, Yuichiro Tada, Hideaki Hirai, Daisuke Kawakita, Satoshi Kano, Kiyoaki Tsukahara, Akira Shimizu, Soichiro Takase, Yorihisa Imanishi, Hiroyuki Ozawa, Kenji Okami, Yuichiro Sato, Yukiko Sato, Chihiro Fushimi, Hideaki Takahashi, Takuro Okada, Hiroki Sato, Kuninori Otsuka, Yoshihiro Watanabe, Akihiro Sakai, Koji Ebisumoto, Takafumi Togashi, Yushi Ueki, Hisayuki Ota, Mizuo Ando, Shinji Kohsaka, Toyoyuki Hanazawa, Hideaki Chazono, Yoshiyuki Kadokura, Hitome Kobayashi, Toshitaka Nagao

Published Dec 4, 2017 · Vol. 9, No. 2 · pp. 1852-1867

Comparing the genomes of cutaneous melanoma tumors to commercially available cell lines Research Paper

Stephen A. Luebker, Weiwei Zhang, Scott A. Koepsell

Published Dec 4, 2017 · Vol. 8, No. 70 · pp. 114877-114893

New role of ID3 in melanoma adaptive drug-resistance Research Paper

Sachindra , Lionel LarribÃ¨re, Daniel Novak, Huizi Wu, Laura HÃ¼ser, Karol Granados, Elias Orouji, Jochen Utikal

Published Nov 27, 2017 · Vol. 8, No. 66 · pp. 110166-110175

Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

Doris Helbig, Alexander Quaas, Cornelia Mauch, Sabine Merkelbach-Bruse, Reinhard BÃ¼ttner, Michael Emberger, Marion Wobser, Vanessa RÃ¼sseler, Katharina PÃ¼tz, Elke Binot, Jan Rehker, Jan Budczies, Michaela Angelika Ihle

Published Nov 25, 2017 · Vol. 8, No. 65 · pp. 109457-109467

Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression Research Paper

Yea Eun Kang, Jin-Man Kim, Koon Soon Kim, Joon Young Chang, Mingyu Jung, Junguee Lee, Shinae Yi, Hyeon Woo Kim, Jung Tae Kim, Kyungmin Lee, Min Jeong Choi, Seul Ki Kang, Seong Eun Lee, Hyon-Seung Yi, Bon Seok Koo, Minho Shong

Published Nov 25, 2017 · Vol. 8, No. 70 · pp. 114980-114994

Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells Research Paper

Matthew L. Fisher, Daniel Grun, Gautam Adhikary, Wen Xu, Richard L. Eckert

Published Nov 22, 2017 · Vol. 8, No. 66 · pp. 110257-110272

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Distinct histone modifications denote early stress-induced drug tolerance in cancer Priority Research Paper

Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo Research Paper

Targeting the cyclin dependent kinase and retinoblastoma axis overcomes standard of care resistance in BRAF^V600E-mutant melanoma Research Paper

Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer Research Paper

Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement Research Paper

A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma Research Paper

The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth Research Paper

Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma Research Paper

Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis Research Paper

Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations Research Paper

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models Research Paper

Targeting the PTTG1 oncogene impairs proliferation and invasiveness of melanoma cells sensitive or with acquired resistance to the BRAF inhibitor dabrafenib Research Paper

LKB1 loss cooperating with BRAF V600E promotes melanoma cell invasion and migration by up-regulation MMP-2 via PI3K/Akt/mTOR pathway Research Paper

Hypoxia-activated prodrug enhances therapeutic effect of sunitinib in melanoma Research Paper

Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas Research Paper

Comparing the genomes of cutaneous melanoma tumors to commercially available cell lines Research Paper

New role of ID3 in melanoma adaptive drug-resistance Research Paper

Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression Research Paper

Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Distinct histone modifications denote early stress-induced drug tolerance in cancer Priority Research Paper

Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo Research Paper

Targeting the cyclin dependent kinase and retinoblastoma axis overcomes standard of care resistance in BRAFV600E-mutant melanoma Research Paper

Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer Research Paper

Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement Research Paper

A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma Research Paper

The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth Research Paper

Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma Research Paper

Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis Research Paper

Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations Research Paper

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models Research Paper

Targeting the PTTG1 oncogene impairs proliferation and invasiveness of melanoma cells sensitive or with acquired resistance to the BRAF inhibitor dabrafenib Research Paper

LKB1 loss cooperating with BRAF V600E promotes melanoma cell invasion and migration by up-regulation MMP-2 via PI3K/Akt/mTOR pathway Research Paper

Hypoxia-activated prodrug enhances therapeutic effect of sunitinib in melanoma Research Paper

Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas Research Paper

Comparing the genomes of cutaneous melanoma tumors to commercially available cell lines Research Paper

New role of ID3 in melanoma adaptive drug-resistance Research Paper

Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression Research Paper

Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells Research Paper

Targeting the cyclin dependent kinase and retinoblastoma axis overcomes standard of care resistance in BRAF^V600E-mutant melanoma Research Paper