The Oncosearch | Oncotarget

Metanephric adenoma: molecular study and review of the literature Research Paper

Enrique Rodríguez-Zarco, Jesús Machuca-Aguado, Laura Macías-García, Ana Vallejo-Benítez, Juan José Ríos-Martín

Published Feb 1, 2022 · Vol. 13, No. 1 · pp. 387-392

Keywords: metanephric adenoma, BRAF, renal neoplasms

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

Robert Hsu, Yasmine Baca, Joanne Xiu, Rongfu Wang, J. Nicholas Bodor, Chul Kim, Hina Khan, Hirva Mamdani, Misako Nagasaka, Sonam Puri, Stephen V. Liu, W. Michael Korn, Jorge J. Nieva

Published Nov 13, 2021 · Vol. 12, No. 25 · pp. 2449-2458

Keywords: lung cancer, tumor microenvironment, diagnostic biomarkers, biomarkers for immunotherapy, cancer testis antigen

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Kelsey E. Huntington, Anna Louie, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 11, 2021 · Vol. 12, No. 20 · pp. 1980-1991

Keywords: cytokine profiling, inflammatory response, chemokine, growth factor, immune profiling

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

Alice Augenlicht, Manuel Saiselet, Myriam Decaussin-Petrucci, Guy Andry, Jacques E. Dumont, Carine Maenhaut

Published Jul 17, 2021 · Vol. 12, No. 16 · pp. 1587-1599

Keywords: miRNA, papillary thyroid carcinoma, IRS2, MAPK, PI3K

Correction: BRAF^V600E-mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma Correction

M. Herman Chui, Susanne K. Kjaer, Kirsten Frederiksen, Charlotte G. Hannibal, Tian-Li Wang, Russell Vang, Ie-Ming Shih

Published Jun 16, 2021 · Vol. 12, No. 13 · pp. 1323-1324

Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra^® Research Paper

Tracey White, Szabolcs Szelinger, Janine LoBello, Amy King, Jessica Aldrich, Nathan Garinger, Matthew Halbert, Ryan F. Richholt, Stephen D. Mastrian, Cody Babb, Audrey A. Ozols, Laurie J. Goodman, Gargi D. Basu, Thomas Royce

Published Apr 7, 2021 · Vol. 12, No. 8 · pp. 726-739

Keywords: comprehensive genomic profiling, whole exome sequencing, RNA sequencing, precision medicine, pan-cancer

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Aditya Kulkarni, Joseph Ryan McDermott, Umesh Kathad, Rama Modali, Jean-Philippe Richard, Panna Sharma, Kishor Bhatia

Published Apr 5, 2021 · Vol. 12, No. 8 · pp. 791-806

Keywords: non-small cell lung cancer, acylfulvene, alkylating agent, PTGR1, LP-184

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

Leonardo G. da Fonseca, Carla Fuster-Anglada, Cristina Carrera, Cristina Millán, Esther Samper, Victor Sapena, Álvaro Díaz-González, Marco Sanduzzi-Zamparelli, Cassia Leal, Alejandro Forner, Jordi Bruix, Maria Reig, Loreto Boix, Alba Díaz

Published Feb 5, 2021 · Vol. 12, No. 5 · pp. 440-449

Keywords: hepatocellular carcinoma, tyrosine kinase inhibitors, treatment adverse events, skin lesions, molecular profiling

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Harish Potu, Malathi Kandarpa, Luke F. Peterson, Alison Durham, Nicholas J. Donato, Moshe Talpaz

Published Jan 12, 2021 · Vol. 12, No. 3 · pp. 160-172

Keywords: melanoma, deubiquitinase (DUB) enzyme, transcription factors, USP9X, DUB inhibitor

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Rolando Pérez-Lorenzo, Stephanie O. Erjavec, Angela M. Christiano, Raphael Clynes

Published Jan 6, 2021 · Vol. 12, No. 2 · pp. 66-80

Keywords: anti-tumor antibodies, targeted therapy, immunotherapy, combination therapies, melanoma

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Marie-Luise Hilbers, Regula Brändli, Beda Mühleisen, Sandra N. Freiberger, Joanna Mangana, Reinhard Dummer

Published Dec 18, 2020 · Vol. 12, No. 2 · pp. 125-130

Keywords: spitzoid nevi, melanocytic lesion, dermatopathology, pediatric dermatology, diagnostic algorithm

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Vânia Gonçalves, Andreia F.A. Henriques, Paulo Matos, Peter Jordan

Published Nov 9, 2020 · Vol. 11, No. 47 · pp. 4421-4437

Keywords: ibuprofen, protein kinase, RAC1B, alternative splicing, colorectal cancer cells

Detection of BRAF splicing variants in plasma-derived cell-free nucleic acids and extracellular vesicles of melanoma patients failing targeted therapy therapies Research Paper

Michael E. Clark, Helen Rizos, Michelle R. Pereira, Ashleigh C. McEvoy, Gabriela Marsavela, Leslie Calapre, Katie Meehan, Olivia Ruhen, Muhammad A. Khattak, Tarek M. Meniawy, Georgina V. Long, Matteo S. Carlino, Alexander M. Menzies, Michael Millward, Melanie Ziman, Elin S. Gray

Published Oct 22, 2020 · Vol. 11, No. 44 · pp. 4016-4027

Keywords: melanoma, targeted therapy, drug resistance, BRAF splicing, extracellular vesicles

MEK inhibitors in non-V600 BRAF mutations and fusions Research Perspective

Douglas B. Johnson, Caroline A. Nebhan, Marcus S. Noel

Published Oct 22, 2020 · Vol. 11, No. 44 · pp. 3900-3903

Keywords: trametinib, MEK, BRAF, atypical, fusion

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

Rikio Suzuki, Yuka Kitamura, Yoshihiko Nakamura, Hibiki Akashi, Yoshiaki Ogawa, Hiroshi Kawada, Kiyoshi Ando

Published Oct 7, 2020 · Vol. 11, No. 44 · pp. 3984-3997

Keywords: pan-RAF inhibitor, Bim, FOXO3a, bortezomib, lenalidomide

A case report of metastatic giant sarcomatoid melanoma with BRAF V600E mutation: a complete response to targeted therapy Case Report

Matteo Torresetti, Donatella Brancorsini, Francesca Morgese, Valeria Cognigni, Alessandro Scalise, Rossana Berardi, Giovanni Di Benedetto

Published Jul 30, 2020 · Vol. 11, No. 34 · pp. 3256-3262

Keywords: sarcomatoid melanoma, giant melanoma, BRAF mutation, targeted therapy, next-generation sequencing

Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases Research Paper

Gino K. In, Kelsey Poorman, Michelle Saul, Steven O’Day, Jeffrey M. Farma, Anthony J. Olszanski, Michael S. Gordon, Jacob S. Thomas, Burton Eisenberg, Lawrence Flaherty, Amy Weise, Steven Daveluy, Geoffrey Gibney, Michael B. Atkins, Ari Vanderwalde

Published Jul 16, 2020 · Vol. 11, No. 33 · pp. 3118-3128

Keywords: melanoma, brain metastases, BRAF, PD-L1, TMB

Paradox breaker BRAF inhibitors have comparable potency and MAPK pathway reactivation to encorafenib in BRAF mutant colorectal cancer Research Paper

Oliver J. Pickles, Aneta Drozd, Louise Tee, Andrew D. Beggs, Gary W. Middleton

Published Jul 13, 2020 · Vol. 11, No. 34 · pp. 3188-3197

Keywords: colorectal cancer, BRAF, paradox breaker, encorafenib, PLX8394

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Aneta Borkowska, Anna Szumera-Ciećkiewicz, Mateusz Spałek, Paweł Teterycz, Anna Czarnecka, Artur Kowalik, Piotr Rutkowski

Published Jun 8, 2020 · Vol. 11, No. 25 · pp. 2404-2413

Keywords: melanoma, acral melanoma, subungual melanoma, nail apparatus melanoma, SMAD4

Phase I study of vemurafenib in children with recurrent or progressive BRAF^V600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) Research Paper

Theodore Nicolaides, Kellie J. Nazemi, John Crawford, Lindsay Kilburn, Jane Minturn, Amar Gajjar, Karen Gauvain, Sarah Leary, Girish Dhall, Mariam Aboian, Giles Robinson, Janel Long-Boyle, Hechuan Wang, Annette M. Molinaro, Sabine Mueller, Michael Prados

Published May 5, 2020 · Vol. 11, No. 21 · pp. 1942-1952

Keywords: BRAF^V600E, pediatric glioma, vemurafenib, clinical trial

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Metanephric adenoma: molecular study and review of the literature Research Paper

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

Correction: BRAF^V600E-mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma Correction

Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra^® Research Paper

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Detection of BRAF splicing variants in plasma-derived cell-free nucleic acids and extracellular vesicles of melanoma patients failing targeted therapy therapies Research Paper

MEK inhibitors in non-V600 BRAF mutations and fusions Research Perspective

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

A case report of metastatic giant sarcomatoid melanoma with BRAF V600E mutation: a complete response to targeted therapy Case Report

Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases Research Paper

Paradox breaker BRAF inhibitors have comparable potency and MAPK pathway reactivation to encorafenib in BRAF mutant colorectal cancer Research Paper

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Phase I study of vemurafenib in children with recurrent or progressive BRAF^V600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Metanephric adenoma: molecular study and review of the literature Research Paper

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

Correction: BRAFV600E-mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma Correction

Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra® Research Paper

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Detection of BRAF splicing variants in plasma-derived cell-free nucleic acids and extracellular vesicles of melanoma patients failing targeted therapy therapies Research Paper

MEK inhibitors in non-V600 BRAF mutations and fusions Research Perspective

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

A case report of metastatic giant sarcomatoid melanoma with BRAF V600E mutation: a complete response to targeted therapy Case Report

Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases Research Paper

Paradox breaker BRAF inhibitors have comparable potency and MAPK pathway reactivation to encorafenib in BRAF mutant colorectal cancer Research Paper

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) Research Paper

Correction: BRAF^V600E-mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma Correction

Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra^® Research Paper

Phase I study of vemurafenib in children with recurrent or progressive BRAF^V600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) Research Paper