The Oncosearch | Oncotarget

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA Research Paper

Aishwarya Subramanian, Adrian Andronache, Yao-Cheng Li, Mark Wade

Published Feb 21, 2016 · Vol. 7, No. 13 · pp. 15986-16002

Overcoming resistance of targeted EGFR monotherapy by inhibition of STAT3 escape pathway in soft tissue sarcoma Research Paper

Xiaochun Wang, David Goldstein, Philip J. Crowe, Mark Yang, Kerryn Garrett, Nikolajs Zeps, Jia-Lin Yang

Published Feb 17, 2016 · Vol. 7, No. 16 · pp. 21496-21509

Involvement of calprotectin (S100A8/A9) in molecular pathways associated with HNSCC Research Paper

Ali Khammanivong, Brent S. Sorenson, Karen F. Ross, Erin B. Dickerson, Rifat Hasina, Mark W. Lingen, Mark C. Herzberg

Published Feb 13, 2016 · Vol. 7, No. 12 · pp. 14029-14047

Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS Research Paper

Rashmi Kanagal-Shamanna, Rajyalakshmi Luthra, Cameron C. Yin, Keyur P. Patel, Koichi Takahashi, Xinyan Lu, John Lee, Chong Zhao, Francesco Stingo, Zhuang Zuo, Mark J. Routbort, Rajesh R. Singh, Patricia Fox, Farhad Ravandi, Guillermo Garcia-Manero, L. Jeffrey Medeiros, Carlos E. Bueso-Ramos

Published Feb 12, 2016 · Vol. 7, No. 12 · pp. 14251-14258

Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport Research Paper

Martin Michaelis, Florian Rothweiler, Mario Wurglics, NatÃ¡lia Aniceto, Michaela Dittrich, Heiko Zettl, Michael Wiese, Mark Wass, Taravat Ghafourian, Manfred Schubert-Zsilavecz, Jindrich Cinatl

Published Feb 12, 2016 · Vol. 7, No. 10 · pp. 11664-11676

Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology Research Paper

James Che, Victor Yu, Manjima Dhar, Corinne Renier, Melissa Matsumoto, Kyra Heirich, Edward B. Garon, Jonathan Goldman, Jianyu Rao, George W. Sledge, Mark D. Pegram, Shruti Sheth, Stefanie S. Jeffrey, Rajan P. Kulkarni, Elodie Sollier, Dino Di Carlo

Published Feb 6, 2016 · Vol. 7, No. 11 · pp. 12748-12760

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Eva A. Ebbing, Jan Paul Medema, Helene Damhofer, Sybren L. Meijer, Kausilia K. Krishnadath, Mark I. van Berge Henegouwen, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven

Published Feb 5, 2016 · Vol. 7, No. 9 · pp. 10243-10254

Perlecan/HSPG2 and matrilysin/MMP-7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients Research Paper

Brian Grindel, Quanlin Li, Rebecca Arnold, John Petros, Majd Zayzafoon, Mark Muldoon, James Stave, Leland W. K. Chung, Mary C. Farach-Carson

Published Feb 4, 2016 · Vol. 7, No. 9 · pp. 10433-10447

The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells Research Paper

Mark R. Pickard, Gwyn T. Williams

Published Feb 3, 2016 · Vol. 7, No. 9 · pp. 10104-10116

Small molecule screen for inhibitors of expression from canonical CREB response element-containing promoters Research Paper

Bryan Mitton, Katie Hsu, Ritika Dutta, Bruce C. Tiu, Nick Cox, Kevin G. McLure, Hee-Don Chae, Mark Smith, Elizabeth A. Eklund, David E. Solow-Cordero, Kathleen M. Sakamoto

Published Jan 30, 2016 · Vol. 7, No. 8 · pp. 8653-8662

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas Research Paper

Devin G. Roller, Brian Capaldo, Stefan Bekiranov, Aaron J. Mackey, Mark R. Conaway, Emanuel F. Petricoin, Daniel Gioeli, Michael J. Weber

Published Dec 10, 2015 · Vol. 7, No. 3 · pp. 2734-2753

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

Thanh Kha Phan, Fung T. Lay, Ivan K.H. Poon, Mark G. Hinds, Marc Kvansakul, Mark D. Hulett

Published Dec 9, 2015 · Vol. 7, No. 2 · pp. 2054-2069

Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer Research Paper

Tommaso De Marchi, Anne M. Timmermans, Marcel Smid, Maxime P. Look, Christoph Stingl, Mark Opdam, Sabine C. Linn, Fred C. G. J. Sweep, Paul N. Span, Mike Kliffen, Carolien H. M. van Deurzen, Theo M. Luider, John A. Foekens, John W. Martens, Arzu Umar

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3098-3110

Understanding genome structural variations Editorial

Alexej Abyzov, Shantao Li, Mark B. Gerstein

Published Dec 7, 2015 · Vol. 7, No. 7 · pp. 7370-7371

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAF^V600E patient-derived papillary thyroid carcinoma preclinical model Priority Research Paper

Mark Duquette, Peter M. Sadow, Amjad Husain, Jennifer N. Sims, Zeus A. Antonello, Andrew H. Fischer, Chen Song, Elena Castellanos-Rizaldos, G. Mike Makrigiorgos, Junichi Kurebayashi, Vania Nose, Paul Van Hummelen, Roderick T. Bronson, Michelle Vinco, Thomas J. Giordano, Dora Dias-Santagata, Pier Paolo Pandolfi, Carmelo Nucera

Published Nov 30, 2015 · Vol. 6, No. 40 · pp. 42445-42467

Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism Research Paper

Lianne E. Rotin, Marcela Gronda, Neil MacLean, Rose Hurren, XiaoMing Wang, Feng-Hsu Lin, Jeff Wrana, Alessandro Datti, Dwayne L. Barber, Mark D. Minden, Malik Slassi, Aaron D. Schimmer

Published Nov 27, 2015 · Vol. 7, No. 3 · pp. 2765-2779

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation Priority Research Paper

Katerina Mardilovich, Mark Baugh, Diane Crighton, Dominika Kowalczyk, Mads Gabrielsen, June Munro, Daniel R. Croft, Filipe Lourenco, Daniel James, Gabriella Kalna, Lynn McGarry, Oliver Rath, Emma Shanks, Mathew J. Garnett, Ultan McDermott, Joanna Brookfield, Mark Charles, Tim Hammonds, Michael F. Olson

Published Nov 3, 2015 · Vol. 6, No. 36 · pp. 38469-38486

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer Research Paper

Thomas A. Mace, Reena Shakya, Omar Elnaggar, Kristin Wilson, Hannah M. Komar, Jennifer Yang, Jason R. Pitarresi, Gregory S. Young, Michael C. Ostrowski, Thomas Ludwig, Tanios Bekaii-Saab, Mark Bloomston, Gregory B. Lesinski

Published Oct 31, 2015 · Vol. 6, No. 42 · pp. 44509-44522

Phosphorylation of Nucleophosmin at Threonine 234/237 is associated with HCC metastasis Research Paper

Rachel Hiu Ha Ching, Eunice Yuen Ting Lau, Patrick Ming Tat Ling, Joyce Man Fong Lee, Mark Kin Fai Ma, Bowie Yik Ling Cheng, Regina Cheuk Lam Lo, Irene Oi Lin Ng, Terence Kin Wah Lee

Published Oct 30, 2015 · Vol. 6, No. 41 · pp. 43483-43495

The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo Research Paper

Frank P. Vendetti, Alan Lau, Sandra Schamus, Thomas P. Conrads, Mark J. Oâ€™Connor, Christopher J. Bakkenist

Published Oct 27, 2015 · Vol. 6, No. 42 · pp. 44289-44305

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Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA Research Paper

Overcoming resistance of targeted EGFR monotherapy by inhibition of STAT3 escape pathway in soft tissue sarcoma Research Paper

Involvement of calprotectin (S100A8/A9) in molecular pathways associated with HNSCC Research Paper

Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS Research Paper

Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport Research Paper

Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology Research Paper

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Perlecan/HSPG2 and matrilysin/MMP-7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients Research Paper

The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells Research Paper

Small molecule screen for inhibitors of expression from canonical CREB response element-containing promoters Research Paper

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas Research Paper

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer Research Paper

Understanding genome structural variations Editorial

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAF^V600E patient-derived papillary thyroid carcinoma preclinical model Priority Research Paper

Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism Research Paper

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation Priority Research Paper

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer Research Paper

Phosphorylation of Nucleophosmin at Threonine 234/237 is associated with HCC metastasis Research Paper

The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA Research Paper

Overcoming resistance of targeted EGFR monotherapy by inhibition of STAT3 escape pathway in soft tissue sarcoma Research Paper

Involvement of calprotectin (S100A8/A9) in molecular pathways associated with HNSCC Research Paper

Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS Research Paper

Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport Research Paper

Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology Research Paper

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Perlecan/HSPG2 and matrilysin/MMP-7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients Research Paper

The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells Research Paper

Small molecule screen for inhibitors of expression from canonical CREB response element-containing promoters Research Paper

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas Research Paper

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer Research Paper

Understanding genome structural variations Editorial

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model Priority Research Paper

Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism Research Paper

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation Priority Research Paper

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer Research Paper

Phosphorylation of Nucleophosmin at Threonine 234/237 is associated with HCC metastasis Research Paper

The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo Research Paper

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAF^V600E patient-derived papillary thyroid carcinoma preclinical model Priority Research Paper