The Oncosearch | Oncotarget

Molecular mechanisms of human IRE1 activation through dimerization and ligand binding Research Paper

Amar Joshi, Yvette Newbatt, P. Craig McAndrew, Mark Stubbs, Rosemary Burke, Mark W. Richards, Chitra Bhatia, John J. Caldwell, Tatiana McHardy, Ian Collins, Richard Bayliss

Published Apr 18, 2015 · Vol. 6, No. 15 · pp. 13019-13035

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis Clinical Research Papers

Anish Thomas, Yuanbin Chen, Seth M. Steinberg, Ji Luo, Svetlana Pack, Mark Raffeld, Zied Abdullaev, Christine Alewine, Arun Rajan, Giuseppe Giaccone, Ira Pastan, Markku Miettinen, Raffit Hassan

Published Apr 13, 2015 · Vol. 6, No. 13 · pp. 11694-11703

Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization Research Paper

Shilpa Bhatia, Nimrah A. Baig, Olga Timofeeva, Elena B. Pasquale, Kellen Hirsch, Tobey J. MacDonald, Anatoly Dritschilo, Yi Chien Lee, Mark Henkemeyer, Brian Rood, Mira Jung, Xiao-Jing Wang, Marcel Kool, Olga Rodriguez, Chris Albanese, Sana D. Karam

Published Mar 30, 2015 · Vol. 6, No. 11 · pp. 8929-8946

Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer Research Paper

InÃ¨s Dufait, Julia Katharina Schwarze, Therese Liechtenstein, Wim Leonard, Heng Jiang, David Escors, Mark De Ridder, Karine Breckpot

Published Mar 29, 2015 · Vol. 6, No. 14 · pp. 12369-12382

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

Hui Xu, Shervin Rahimpour, Cody L. Nesvick, Xu Zhang, Jingyun Ma, Min Zhang, Ge Zhang, Li Wang, Chunzhang Yang, Christopher S. Hong, Anand V. Germanwala, J. Bradley Elder, Abhik Ray-Chaudhury, Yu Yao, Mark R. Gilbert, Russell R. Lonser, John D. Heiss, Roscoe O. Brady, Ying Mao, Jianhua Qin, Zhengping Zhuang

Published Mar 14, 2015 · Vol. 6, No. 14 · pp. 11882-11893

C-terminal domain of SMYD3 serves as a unique HSP90-regulated motif in oncogenesis Research Paper

Mark A. Brown, Kenneth Foreman, June Harriss, Chhaya Das, Li Zhu, Melissa Edwards, Salam Shaaban, Haley Tucker

Published Mar 2, 2015 · Vol. 6, No. 6 · pp. 4005-4019

Oncogenic mutations of thyroid hormone receptor Î² Research Paper

Jeong Won Park, Li Zhao, Mark Willingham, Sheue-yann Cheng

Published Feb 28, 2015 · Vol. 6, No. 10 · pp. 8115-8131

Multilevel-analysis identify a cis-expression quantitative trait locus associated with risk of renal cell carcinoma Research Paper

Xiang Shu, Mark P. Purdue, Yuanqing Ye, Christopher G. Wood, Meng Chen, Zhaoming Wang, Demetrius Albanes, Xia Pu, Maosheng Huang, Victoria L. Stevens, W. Ryan Diver, Susan M. Gapstur, Jarmo Virtamo, Wong-Ho Chow, Nizar M. Tannir, Colin P. Dinney, Nathaniel Rothman, Stephen J. Chanock, Xifeng Wu

Published Feb 25, 2015 · Vol. 6, No. 6 · pp. 4097-4109

14q32-encoded microRNAs mediate an oligometastatic phenotype Priority Research Paper

Abhineet Uppal, Sean C. Wightman, Stephen Mallon, Go Oshima, Sean P. Pitroda, Qingbei Zhang, Xiaona Huang, Thomas E. Darga, Lei Huang, Jorge Andrade, Huiping Liu, Mark K. Ferguson, Geoffrey L. Greene, Mitchell C. Posner, Samuel Hellman, Nikolai N. Khodarev, Ralph R. Weichselbaum

Published Feb 18, 2015 · Vol. 6, No. 6 · pp. 3540-3552

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition Research Paper

Marta Kovatcheva, David D. Liu, Mark A. Dickson, Mary E. Klein, Rachael Oâ€™Connor, Fatima O. Wilder, Nicholas D. Socci, William D. Tap, Gary K. Schwartz, Samuel Singer, Aimee M. Crago, Andrew Koff

Published Jan 31, 2015 · Vol. 6, No. 10 · pp. 8226-8243

Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs Research Paper

Isabel Ben-Batalla, Miguel Cubas-Cordova, Florian Udonta, Mark Wroblewski, Jonas S. Waizenegger, Melanie Janning, Stefanie Sawall, Victoria Gensch, Lin Zhao, IÃ±igo Martinez-Zubiaurre, Kristoffer Riecken, Boris Fehse, Klaus Pantel, Carsten Bokemeyer, Sonja Loges

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6341-6358

Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts Research Paper

Ridwana Chowdhury, Jason P. Webber, Mark Gurney, Malcolm D. Mason, Zsuzsanna Tabi, Aled Clayton

Published Jan 22, 2015 · Vol. 6, No. 2 · pp. 715-731

Keywords: exosomes, cancer stroma, mesenchymal stem cells, prostate cancer

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma Research Paper

Ziming Du, Malak Abedalthagafi, Ayal A. Aizer, Allison R. McHenry, Heather H. Sun, Mark-Anthony Bray, Omar Viramontes, Revaz Machaidze, Priscilla K. Brastianos, David A. Reardon, Ian F. Dunn, Gordon J. Freeman, Keith L. Ligon, Anne E. Carpenter, Brian M. Alexander, Nathalie Y. Agar, Scott J. Rodig, Elizabeth M. Bradshaw, Sandro Santagata

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4704-4716

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

Sebastian SchÃ¶lch, Conrad Rauber, Alexandra Tietz, Nuh N. Rahbari, Ulrich Bork, Thomas Schmidt, Christoph Kahlert, Uwe Haberkorn, Mark A. Tomai, Kenneth E. Lipson, Rafael Carretero, JÃ¼rgen Weitz, Moritz Koch, Peter E. Huber

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4663-4676

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Hua Li, Grace Y. Sun, Yongchao Zhao, Dafydd Thomas, Joel K. Greenson, Mark M. Zalupski, Edgar Ben-Josef, Yi Sun

Published Dec 30, 2014 · Vol. 5, No. 24 · pp. 12811-12819

Keywords: DEPTOR, mTOR pathway, pancreatic cancer, growth suppression

Classification of current anticancer immunotherapies Review

Lorenzo Galluzzi, Erika Vacchelli, JosÃ©-Manuel Bravo-San Pedro, Aitziber BuquÃ©, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka FuÄÃkovÃ¡, Dmitry I. Gabrilovich, JÃ©rÃ´me Galon, Abhishek Garg, FranÃ§ois Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk JÃ¤ger, Pawel Kalinski, Klas KÃ¤rre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine SautÃ¨s-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, BenoÃ®t J. Van Den Eynde, Richard Vile, Hermann Wagner, JeffreyÂ S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, Guido Kroemer

Published Dec 18, 2014 · Vol. 5, No. 24 · pp. 12472-12508

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Teeru Bihani, Scott A. Ezell, Brendon Ladd, Shaun E. Grosskurth, Anne Marie Mazzola, Mark Pietras, Corinne Reimer, Michael Zinda, Stephen Fawell, Celina M. Dâ€™Cruz

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2407-2420

Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform Clinical Research Papers

Evelyn Kidess, Kyra Heirich, Matthew Wiggin, Valentina Vysotskaia, Brendan C. Visser, Andre Marziali, Bertram Wiedenmann, Jeffrey A. Norton, Mark Lee, Stefanie S. Jeffrey, George A. Poultsides

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2549-2561

Aspartate Î²-hydroxylase expression promotes a malignant pancreatic cellular phenotype Research Paper

Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Yu Li, Chiung-Kuei Huang, Waihong Chung, Qi Tang, Xuesong Chen, Rolf Carlson, Christina Nadolny, Gregory Gabriel, Mark Olsen, Jack R. Wands

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1231-1248

Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells Research Paper

Vincenzo Desiderio, Petros Papagerakis, Virginia Tirino, Li Zheng, Margarite Matossian, Mark E. Prince, Francesca Paino, Luigi Mele, Federica Papaccio, Roberta Montella, Gianpaolo Papaccio, Silvana Papagerakis

Published Nov 6, 2014 · Vol. 6, No. 1 · pp. 71-84

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Molecular mechanisms of human IRE1 activation through dimerization and ligand binding Research Paper

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis Clinical Research Papers

Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization Research Paper

Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer Research Paper

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

C-terminal domain of SMYD3 serves as a unique HSP90-regulated motif in oncogenesis Research Paper

Oncogenic mutations of thyroid hormone receptor Î² Research Paper

Multilevel-analysis identify a cis-expression quantitative trait locus associated with risk of renal cell carcinoma Research Paper

14q32-encoded microRNAs mediate an oligometastatic phenotype Priority Research Paper

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition Research Paper

Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs Research Paper

Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts Research Paper

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma Research Paper

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Classification of current anticancer immunotherapies Review

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform Clinical Research Papers

Aspartate Î²-hydroxylase expression promotes a malignant pancreatic cellular phenotype Research Paper

Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Molecular mechanisms of human IRE1 activation through dimerization and ligand binding Research Paper

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis Clinical Research Papers

Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization Research Paper

Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer Research Paper

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

C-terminal domain of SMYD3 serves as a unique HSP90-regulated motif in oncogenesis Research Paper

Oncogenic mutations of thyroid hormone receptor Î² Research Paper

Multilevel-analysis identify a cis-expression quantitative trait locus associated with risk of renal cell carcinoma Research Paper

14q32-encoded microRNAs mediate an oligometastatic phenotype Priority Research Paper

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition Research Paper

Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs Research Paper

Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts Research Paper

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma Research Paper

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Classification of current anticancer immunotherapies Review

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform Clinical Research Papers

Aspartate Î²-hydroxylase expression promotes a malignant pancreatic cellular phenotype Research Paper

Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells Research Paper