Oncotarget

Vol 11, No 46

November 17, 2020

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About The Cover

The cover for issue 46 of Oncotarget features Figure 6, "Establishment of a SARS-CoV-2 pseudovirus that expresses SPIKE protein variants on the envelope of a lentiviral core, infection of human airway epithelial cells or lung cancer cells, and demonstration of MEKi attenuation of infectivity on primary human cells," by Zhou, et al.

Table of Contents

Priority Research Papers

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection

https://doi.org/10.18632/oncotarget.27799

Lanlan Zhou, Kelsey Huntington, Shengliang Zhang, Lindsey Carlsen, Eui-Young So, Cassandra Parker, Ilyas Sahin, Howard Safran, Suchitra Kamle, Chang-Min Lee, Chun Geun Lee, Jack A. Elias, Kerry S. Campbell, Mandar T. Naik, Walter J. Atwood, Emile Youssef, Jonathan A. Pachter, Arunasalam Navaraj, Attila A. Seyhan, Olin Liang,  and Wafik S. El-Deiry
4201-4223
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism

https://doi.org/10.18632/oncotarget.27815

Abram Calderon, Samantha S. Soldan, Alessandra De Leo, Zhong Deng, Drew M. Frase, Emma M. Anderson, Yue Zhang, Olga Vladimirova, Fang Lu, Jessica C. Leung, Maureen E. Murphy,  and Paul M. Lieberman
4224-4242
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer

Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer

https://doi.org/10.18632/oncotarget.27818

Bigang Liu, Rahul Kumar, Hseuh-Ping Chao, Rashid Mehmood, Yibing Ji, Amanda Tracz,  and Dean G. Tang
4243-4252
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Immune profiling of the bone marrow microenvironment in patients with high-risk localized prostate cancer

Immune profiling of the bone marrow microenvironment in patients with high-risk localized prostate cancer

https://doi.org/10.18632/oncotarget.27817

Erika Heninger, Nan Sethakorn, David Kosoff, Peiman Hematti, Morgan D. Kuczler, Kenneth J. Pienta,  and Joshua M. Lang
4253-4265
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Auto-antibodies against apolipoprotein A-1 block cancer cells proliferation and induce apoptosis

Auto-antibodies against apolipoprotein A-1 block cancer cells proliferation and induce apoptosis

https://doi.org/10.18632/oncotarget.27814

Nathalie Satta, Rémy Weppe, Sabrina Pagano, Miguel Frias, Catherine Juillard,  and Nicolas Vuilleumier
4266-4280
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Phase I dose escalation study of 12b80 (hydroxybisphosphonate linked doxorubicin) in naturally occurring osteosarcoma

Phase I dose escalation study of 12b80 (hydroxybisphosphonate linked doxorubicin) in naturally occurring osteosarcoma

https://doi.org/10.18632/oncotarget.27801

Pierre Boyé, Emmanuelle David, François Serres, Quentin Pascal, Franck Floch, Kévyn Geeraert, Virginie Coste, Laurent Marescaux, Sébastien Cagnol, Jean-Yves Goujon, Maxim Egorov, Ronan Le Bot,  and Dominique Tierny
4281-4292
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Identification of novel prognostic markers of survival time in high-risk neuroblastoma using gene expression profiles

Identification of novel prognostic markers of survival time in high-risk neuroblastoma using gene expression profiles

https://doi.org/10.18632/oncotarget.27808

Abdulazeez Giwa, Azeez Fatai, Junaid Gamieldien, Alan Christoffels,  and Hocine Bendou
4293-4305
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

MicroRNA-based regulation of Aurora A kinase in breast cancer

MicroRNA-based regulation of Aurora A kinase in breast cancer

https://doi.org/10.18632/oncotarget.27811

Adewale Oluwaseun Fadaka, Nicole Remaliah Samantha Sibuyi, Abram Madimabe Madiehe,  and Mervin Meyer
4306-4324
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Intracellular hyaluronic acid-binding protein 4 (HABP4): a candidate tumor suppressor in colorectal cancer

Intracellular hyaluronic acid-binding protein 4 (HABP4): a candidate tumor suppressor in colorectal cancer

https://doi.org/10.18632/oncotarget.27804

Talita Diniz Melo-Hanchuk, Carolina Colleti, Ângela Saito, Maria Carolina Santos Mendes, José Barreto Campello Carvalheira, Jose Vassallo,  and Jörg Kobarg
4325-4337
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Reviews

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes

https://doi.org/10.18632/oncotarget.27789

Vic Hart, Hannah Gautrey, John Kirby,  and Alison Tyson-Capper
4338-4357
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Case Reports

A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer

A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer

https://doi.org/10.18632/oncotarget.27809

Sewanti Limaye, Prashant Kumar, Ramya Pragya, Janani Sambath, Darshana Patil, Ajay Srinivasan, Sachin Apurva, Navin Srivastava, Sanket Patil, Revati Patil, Vineet Datta, Dadasaheb Akolkar,  and Rajan Datar
4358-4363
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Order a Reprint

Corrections

Correction: Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines

Correction: Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines

https://doi.org/10.18632/oncotarget.27821

Makhan Kumar, Ansie Martin, Snehal Nirgude, Bibha Chaudhary, Sukanta Mondal,  and Angshuman Sarkar
4364-4365
Correction  |  PDF  |  How to cite


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