The Oncosearch | Oncotarget

In vitro and in vivo anti-leukemic effects of cladoloside C₂ are mediated by activation of Fas/ceramide synthase 6/p38 kinase/ c-Jun NH₂-terminal kinase/caspase-8 Research Paper

Seong-Hoon Yun, Eun-Hye Sim, Sang-Heum Han, Tae-Rang Kim, Mi-Ha Ju, Jin-Yeong Han, Jin-Sook Jeong, Sung-Hyun Kim, Alexandra S. Silchenko, Valentin A. Stonik, Joo-In Park

Published Dec 8, 2017 · Vol. 9, No. 1 · pp. 495-511

Elucidating mechanisms of sunitinib resistance in renal cancer: an integrated pathological-molecular analysis Research Paper

Henriett Butz, Qiang Ding, Roy Nofech-Mozes, Zsuzsanna Lichner, Heyu Ni, George M. Yousef

Published Dec 8, 2017 · Vol. 9, No. 4 · pp. 4661-4674

Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor action Research Paper

Mi Seon Kim, Byong Chul Yoo, Woo Seok Yang, Sang Yun Han, Deok Jeong, Jun Min Song, Kyung Hee Kim, Adithan Aravinthan, Ji Hye Kim, Jong-Hoon Kim, Seung Cheol Kim, Jae Youl Cho

Published Dec 8, 2017 · Vol. 9, No. 5 · pp. 5979-5992

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer Research Paper

Mi Ran Byun, Jin Woo Choi

Published Dec 8, 2017 · Vol. 9, No. 1 · pp. 1041-1047

C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC Research Paper

Xiyan Chen, Weiting Gu, Qi Wang, Xucheng Fu, Ying Wang, Xin Xu, Yong Wen

Published Dec 7, 2017 · Vol. 9, No. 1 · pp. 668-679

Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites Research Paper

Shan Xu, XiaoBo Du, Gang Feng, Yu Zhang, Jie Li, Binwei Lin, LingLin Yang, ShaoZhi Fu, JingBo Wu

Published Dec 6, 2017 · Vol. 9, No. 1 · pp. 282-292

MAEL contributes to gastric cancer progression by promoting ILKAP degradation Research Paper

Xing Zhang, Yichong Ning, Yuzhong Xiao, Huaxin Duan, Guifang Qu, Xin Liu, Yan Du, Dejian Jiang, Jianlin Zhou

Published Dec 6, 2017 · Vol. 8, No. 69 · pp. 113331-113344

Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer Research Paper

Hee Jin Lee, Young-Ae Kim, Chan Kyu Sim, Sun-Hee Heo, In Hye Song, Hye Seon Park, Suk Young Park, Won Seon Bang, In Ah Park, Miseon Lee, Jung Hoon Lee, Yeon Sook Cho, Suhwan Chang, Jaeyun Jung, Jisun Kim, Sae Byul Lee, Sung Youl Kim, Myeong Sup Lee, Gyungyub Gong

Published Dec 6, 2017 · Vol. 8, No. 69 · pp. 113345-113359

Evaluation of the combination of the dual m-TORC1/2 inhibitor vistusertib (AZD2014) and paclitaxel in ovarian cancer models Research Paper

Anne-Christine Wong Te Fong, Parames Thavasu, Sladjana Gagrica, Karen E. Swales, Martin O. Leach, Sabina C. Cosulich, Yuen-Li Chung, Udai Banerji

Published Dec 6, 2017 · Vol. 8, No. 69 · pp. 113874-113884

Polo-like-kinase 1 (PLK-1) and c-myc inhibition with the dual kinase-bromodomain inhibitor volasertib in aggressive lymphomas Research Paper

Carlos Murga-Zamalloa, Avery Polk, Walter Hanel, Pinki Chowdhury, Noah Brown, Alexandra C. Hristov, Nathanael G. Bailey, Tianjiao Wang, Tycel Phillips, Sumana Devata, Pradeep Poonnen, Juan Gomez-Gelvez, Kedar V. Inamdar, Ryan A. Wilcox

Published Dec 6, 2017 · Vol. 8, No. 70 · pp. 114474-114480

The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy Research Paper

Justin Greene, Anna Nguyen, Stacey M. Bagby, Gemma N. Jones, WM. Tai, Kevin S. Quackenbush, Anna Schreiber, Wells A. Messersmith, Kalpana M. Devaraj, Patrick Blatchford, S. Gail Eckhardt, Elaine B. Cadogan, Gareth D. Hughes, Aaron Smith, Todd M. Pitts, John J. Arcaroli

Published Dec 5, 2017 · Vol. 8, No. 67 · pp. 110904-110913

Chitosan composite scaffold combined with bone marrow-derived mesenchymal stem cells for bone regeneration: in vitro and in vivo evaluation Research Paper

Shengqi Zang, Lei Zhu, Kefu Luo, Rui Mu, Feng Chen, Xiaocui Wei, Xiaodong Yan, Biyao Han, Xiaolei Shi, Qintao Wang, Lei Jin

Published Dec 5, 2017 · Vol. 8, No. 67 · pp. 110890-110903

Three-dimensional tumor model mimics stromal â€“ breast cancer cells signaling Research Paper

Stephanie Lemmo Ham, Pradip Shahi Thakuri, Madison Plaster, Jun Li, Kathryn E. Luker, Gary D. Luker, Hossein Tavana

Published Dec 5, 2017 · Vol. 9, No. 1 · pp. 249-267

Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model Research Paper

Kentaro Igarashi, Kei Kawaguchi, Tasuku Kiyuna, Kentaro Miyake, Masuyo Miyake, Yunfeng Li, Scott D. Nelson, Sarah M. Dry, Arun S. Singh, Irmina A. Elliott, Tara A. Russell, Mark A. Eckardt, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Hiroyuki Tsuchiya, Fritz C. Eilber, Robert M. Hoffman

Published Dec 4, 2017 · Vol. 9, No. 8 · pp. 7774-7781

YM155 exerts potent cytotoxic activity against quiescent (G₀/G₁) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1 Research Paper

Miyuki Ookura, Tatsuya Fujii, Hideki Yagi, Takuya Ogawa, Shinji Kishi, Naoko Hosono, Hiroko Shigemi, Takahiro Yamauchi, Takanori Ueda, Akira Yoshida

Published Dec 4, 2017 · Vol. 8, No. 67 · pp. 111535-111550

Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis Research Paper

Sang-Hun Kim, Kwang-Youn Kim, Sul-Gi Park, Sun-Nyoung Yu, Young-Wook Kim, Hyo-Won Nam, Hyun-Hee An, Young-Woo Kim, Soon-Cheol Ahn

Published Dec 4, 2017 · Vol. 8, No. 67 · pp. 111581-111596

Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells Research Paper

Monika Bhardwaj, Hee Jun Cho, Souren Paul, Rekha Jakhar, Imran Khan, Seon-Jin Lee, Bo-Yeon Kim, Manigandan Krishnan, Tejinder Pal Khaket, Hee Gu Lee, Sun Chul Kang

Published Dec 4, 2017 · Vol. 9, No. 3 · pp. 3278-3291

Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production Research Paper

Mingguo Huang, Shintaro Narita, Takamitsu Inoue, Atsushi Koizumi, Mitsuru Saito, Hiroshi Tsuruta, Kazuyuki Numakura, Shigeru Satoh, Hiroshi Nanjo, Takehiko Sasaki, Tomonori Habuchi

Published Dec 4, 2017 · Vol. 8, No. 67 · pp. 111780-111794

Bridging the divide: preclinical research discrepancies between triple-negative breast cancer cell lines and patient tumors Review

Andrew Sulaiman, Lisheng Wang

Published Dec 4, 2017 · Vol. 8, No. 68 · pp. 113269-113281

A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models Research Paper

Nannan Zhang, Guo Zhang, Ning Liu, Wanting Lin, Sen Ji, Mingwu Zheng, Kai Chen, Xiao Liang, Guobo Li, Yu Ma, Jun Zhu, Ting Niu, Lin-Li Li, Jiong Li, Yu-Quan Wei, Sheng-Yong Yang

Published Dec 1, 2017 · Vol. 8, No. 67 · pp. 111495-111507

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In vitro and in vivo anti-leukemic effects of cladoloside C₂ are mediated by activation of Fas/ceramide synthase 6/p38 kinase/ c-Jun NH₂-terminal kinase/caspase-8 Research Paper

Elucidating mechanisms of sunitinib resistance in renal cancer: an integrated pathological-molecular analysis Research Paper

Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor action Research Paper

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer Research Paper

C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC Research Paper

Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites Research Paper

MAEL contributes to gastric cancer progression by promoting ILKAP degradation Research Paper

Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer Research Paper

Evaluation of the combination of the dual m-TORC1/2 inhibitor vistusertib (AZD2014) and paclitaxel in ovarian cancer models Research Paper

Polo-like-kinase 1 (PLK-1) and c-myc inhibition with the dual kinase-bromodomain inhibitor volasertib in aggressive lymphomas Research Paper

The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy Research Paper

Chitosan composite scaffold combined with bone marrow-derived mesenchymal stem cells for bone regeneration: in vitro and in vivo evaluation Research Paper

Three-dimensional tumor model mimics stromal â€“ breast cancer cells signaling Research Paper

Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model Research Paper

YM155 exerts potent cytotoxic activity against quiescent (G₀/G₁) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1 Research Paper

Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis Research Paper

Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells Research Paper

Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production Research Paper

Bridging the divide: preclinical research discrepancies between triple-negative breast cancer cell lines and patient tumors Review

A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models Research Paper

Publication Alerts

European Cancer and Oncology Congress

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Post-Publication Promotion

Search Oncotarget

In vitro and in vivo anti-leukemic effects of cladoloside C2 are mediated by activation of Fas/ceramide synthase 6/p38 kinase/ c-Jun NH2-terminal kinase/caspase-8 Research Paper

Elucidating mechanisms of sunitinib resistance in renal cancer: an integrated pathological-molecular analysis Research Paper

Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor action Research Paper

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer Research Paper

C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC Research Paper

Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites Research Paper

MAEL contributes to gastric cancer progression by promoting ILKAP degradation Research Paper

Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer Research Paper

Evaluation of the combination of the dual m-TORC1/2 inhibitor vistusertib (AZD2014) and paclitaxel in ovarian cancer models Research Paper

Polo-like-kinase 1 (PLK-1) and c-myc inhibition with the dual kinase-bromodomain inhibitor volasertib in aggressive lymphomas Research Paper

The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy Research Paper

Chitosan composite scaffold combined with bone marrow-derived mesenchymal stem cells for bone regeneration: in vitro and in vivo evaluation Research Paper

Three-dimensional tumor model mimics stromal â€“ breast cancer cells signaling Research Paper

Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model Research Paper

YM155 exerts potent cytotoxic activity against quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1 Research Paper

Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis Research Paper

Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells Research Paper

Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production Research Paper

Bridging the divide: preclinical research discrepancies between triple-negative breast cancer cell lines and patient tumors Review

A novel orally available Syk/Src/Jak2 inhibitor, SKLB-850, showed potent anti-tumor activities in B cell lymphoma (BCL) models Research Paper

In vitro and in vivo anti-leukemic effects of cladoloside C₂ are mediated by activation of Fas/ceramide synthase 6/p38 kinase/ c-Jun NH₂-terminal kinase/caspase-8 Research Paper

YM155 exerts potent cytotoxic activity against quiescent (G₀/G₁) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1 Research Paper