The Oncosearch | Oncotarget

Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog Research Paper

Bhairavi Tolani, Ngoc T. Hoang, Luis A. Acevedo, Etienne Giroux Leprieur, Hui Li, Biao He, David M. Jablons

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14311-14323

Depleting ovarian cancer stem cells with calcitriol Research Paper

Amit Kumar Srivastava, Asim Rizvi, Tiantian Cui, Chunhua Han, Ananya Banerjee, Imrana Naseem, Yanfang Zheng, Altaf A. Wani, Qi-En Wang

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14481-14491

Novel natural withanolides induce apoptosis and inhibit migration of neuroblastoma cells through down regulation of N-myc and suppression of Akt/mTOR/NF-ÎºB activation Research Paper

Chitra Subramanian, Patrick T. Grogan, Valerie P. Opipari, Barbara N. Timmermann, Mark S. Cohen

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14509-14523

CTBP1 and metabolic syndrome induce an mRNA and miRNA expression profile critical for breast cancer progression and metastasis Research Paper

Paula L. FarrÃ©, Georgina D. Scalise, RocÃo B. Duca, Guillermo N. Dalton, Cintia Massillo, Juliana Porretti, Karen GraÃ±a, Kevin Gardner, Paola De Luca, Adriana De Siervi

Published Feb 13, 2018 · Vol. 9, No. 17 · pp. 13848-13858

Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression Research Paper

Kazuaki Matsuoka, Fumio Nakagawa, Takashi Kobunai, Teiji Takechi

Published Feb 5, 2018 · Vol. 9, No. 17 · pp. 13438-13450

Human tripartite motif protein 52 is required for cell context-dependent proliferation Research Paper

Stefan Benke, Benedikt Agerer, Lisa Haas, Martin StÃ¶ger, Alexander Lercher, Lisa Gabler, Izabella Kiss, Sara Scinicariello, Walter Berger, Andreas Bergthaler, Anna C. Obenauf, Gijs A. Versteeg

Published Feb 5, 2018 · Vol. 9, No. 17 · pp. 13565-13581

Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells Research Paper

Meike Hutt, Sina Fellermeier-Kopf, Oliver Seifert, Lisa C. Schmitt, Klaus Pfizenmaier, Roland E. Kontermann

Published Jan 31, 2018 · Vol. 9, No. 13 · pp. 11322-11335

Colorectal cancer cells require glycogen synthase kinase-3β for sustaining mitosis via translocated promoter region (TPR)-dynein interaction Research Paper

Firli R.P. Dewi, Takahiro Domoto, Masaharu Hazawa, Akiko Kobayashi, Takayuki Douwaki, Toshinari Minamoto, Richard W. Wong

Published Jan 30, 2018 · Vol. 9, No. 17 · pp. 13337-13352

Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression Research Paper

Weihua Li, Huimin Bai, Shiping Liu, Dongyan Cao, Hongying Wu, Keng Shen, Yanhong Tai, Jiaxin Yang

Published Jan 24, 2018 · Vol. 9, No. 15 · pp. 12064-12078

Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development Review

Yousef Zakharia, Arup Bhattacharya, Youcef M. Rustum

Published Jan 23, 2018 · Vol. 9, No. 12 · pp. 10765-10783

MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models Research Paper

Francesca Vena, Ruochen Jia, Arman Esfandiari, Juan J. Garcia-Gomez, Manuel Rodriguez-Justo, Jianguo Ma, Sakeena Syed, Lindsey Crowley, Brian Elenbaas, Samantha Goodstal, John A. Hartley, Daniel Hochhauser

Published Jan 22, 2018 · Vol. 9, No. 14 · pp. 11592-11603

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress Research Paper

Xiangyun Li, Mei Li, Hang Ruan, Wei Qiu, Xiang Xu, Lin Zhang, Jian Yu

Published Jan 22, 2018 · Vol. 8, No. 6 · pp. 9280-9292

Pazopanib radio-sensitization of human sarcoma tumors Research Paper

Feng Wang, Hongyan Li, Ela Markovsky, Ryan Glass, Elisa de Stanchina, Simon N. Powell, Gary K. Schwartz, Adriana Haimovitz-Friedman

Published Jan 20, 2018 · Vol. 9, No. 10 · pp. 9311-9324

Ruxolitinib significantly enhances in vitro apoptosis in Hodgkin lymphoma and primary mediastinal B-cell lymphoma and survival in a lymphoma xenograft murine model Research Paper

Sanghoon Lee, Tishi Shah, Changhong Yin, Jessica Hochberg, Janet Ayello, Erin Morris, Carmella van de Ven, Mitchell S. Cairo

Published Jan 18, 2018 · Vol. 9, No. 11 · pp. 9776-9788

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models Research Paper

Kei Kawaguchi, Qinghong Han, Shukuan Li, Yuying Tan, Kentaro Igarashi, Kentaro Miyake, Tasuku Kiyuna, Masuyo Miyake, Bartosz Bartosz, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Arun S. Singh, Mark A. Eckardt, Michiaki Unno, Fritz C. Eilber, Robert M. Hoffman

Published Jan 17, 2018 · Vol. 9, No. 13 · pp. 11119-11125

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosomeâ€“like acute B-cell lymphoblastic leukemia Research Paper

Qi Zhang, Ce Shi, Lina Han, Nitin Jain, Kathryn G. Roberts, Helen Ma, Tianyu Cai, Antonio Cavazos, Yoko Tabe, Rodrigo O. Jacamo, Hong Mu, Yang Zhao, Jing Wang, Shuo-Chieh Wu, Fenglin Cao, Zhihong Zeng, Jin Zhou, Yingchang Mi, Elias J. Jabbour, Ross Levine, Sarah K. Tasian, Charles G. Mullighan, David M. Weinstock, David A. Fruman, Marina Konopleva

Published Jan 17, 2018 · Vol. 9, No. 8 · pp. 8027-8041

The PCAT3/PCAT9-miR-203-SNAI2 axis functions as a key mediator for prostate tumor growth and progression Research Paper

Fangfang Tao, Xinxin Tian, Zhiqian Zhang

Published Jan 12, 2018 · Vol. 9, No. 15 · pp. 12212-12225

CD30-targeted oncolytic viruses as novel therapeutic approach against classical Hodgkin lymphoma Research Paper

Julia D.S. Hanauer, Benjamin Rengstl, Dina KleinlÃ¼tzum, Johanna Reul, Anett Pfeiffer, Thorsten Friedel, Irene C. Schneider, Sebastian Newrzela, Martin- Leo Hansmann, Christian J. Buchholz, Alexander Muik

Published Jan 12, 2018 · Vol. 9, No. 16 · pp. 12971-12981

Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system Research Paper

Ji Min Oh, Senthilkumar Kalimuthu, Prakash Gangadaran, Se Hwan Baek, Liya Zhu, Ho Won Lee, Ramya Lakshmi Rajendran, Chae Moon Hong, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn

Published Jan 11, 2018 · Vol. 9, No. 6 · pp. 7075-7087

Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers Research Paper

Carole Sourbier, Pei-Jyun Liao, Christopher J. Ricketts, Darmood Wei, Youfeng Yang, Sarah M. Baranes, Benjamin K. Gibbs, Lernik Ohanjanian, L.Spencer Krane, Bradley T. Scroggins, J. Keith Killian, Ming-Hui Wei, Toshiki Kijima, Paul S. Meltzer, Deborah E. Citrin, Len Neckers, Cathy D. Vocke, W. Marston Linehan

Published Jan 10, 2018 · Vol. 9, No. 12 · pp. 10723-10733

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Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog Research Paper

Depleting ovarian cancer stem cells with calcitriol Research Paper

Novel natural withanolides induce apoptosis and inhibit migration of neuroblastoma cells through down regulation of N-myc and suppression of Akt/mTOR/NF-ÎºB activation Research Paper

CTBP1 and metabolic syndrome induce an mRNA and miRNA expression profile critical for breast cancer progression and metastasis Research Paper

Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression Research Paper

Human tripartite motif protein 52 is required for cell context-dependent proliferation Research Paper

Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells Research Paper

Colorectal cancer cells require glycogen synthase kinase-3β for sustaining mitosis via translocated promoter region (TPR)-dynein interaction Research Paper

Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression Research Paper

Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development Review

MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models Research Paper

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress Research Paper

Pazopanib radio-sensitization of human sarcoma tumors Research Paper

Ruxolitinib significantly enhances in vitro apoptosis in Hodgkin lymphoma and primary mediastinal B-cell lymphoma and survival in a lymphoma xenograft murine model Research Paper

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models Research Paper

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosomeâ€“like acute B-cell lymphoblastic leukemia Research Paper

The PCAT3/PCAT9-miR-203-SNAI2 axis functions as a key mediator for prostate tumor growth and progression Research Paper

CD30-targeted oncolytic viruses as novel therapeutic approach against classical Hodgkin lymphoma Research Paper

Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system Research Paper

Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog Research Paper

Depleting ovarian cancer stem cells with calcitriol Research Paper

Novel natural withanolides induce apoptosis and inhibit migration of neuroblastoma cells through down regulation of N-myc and suppression of Akt/mTOR/NF-ÎºB activation Research Paper

CTBP1 and metabolic syndrome induce an mRNA and miRNA expression profile critical for breast cancer progression and metastasis Research Paper

Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression Research Paper

Human tripartite motif protein 52 is required for cell context-dependent proliferation Research Paper

Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells Research Paper

Colorectal cancer cells require glycogen synthase kinase-3β for sustaining mitosis via translocated promoter region (TPR)-dynein interaction Research Paper

Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression Research Paper

Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development Review

MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models Research Paper

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress Research Paper

Pazopanib radio-sensitization of human sarcoma tumors Research Paper

Ruxolitinib significantly enhances in vitro apoptosis in Hodgkin lymphoma and primary mediastinal B-cell lymphoma and survival in a lymphoma xenograft murine model Research Paper

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models Research Paper

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosomeâ€“like acute B-cell lymphoblastic leukemia Research Paper

The PCAT3/PCAT9-miR-203-SNAI2 axis functions as a key mediator for prostate tumor growth and progression Research Paper

CD30-targeted oncolytic viruses as novel therapeutic approach against classical Hodgkin lymphoma Research Paper

Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system Research Paper

Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers Research Paper