The Oncosearch | Oncotarget

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

Md. Nabiul Hasan, Manon Queudeville, Luca Trentin, Sarah Mirjam Eckhoff, Ilaria Bronzini, Chiara Palmi, Thomas Barth, Giovanni Cazzaniga, Geertruy te Kronnie, Klaus-Michael Debatin, LÃ¼der Hinrich Meyer

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1382-1395

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

Huanzhang Hu, Yinghe Qiu, Minggao Guo, Yao Huang, Lin Fang, Zhangxiao Peng, Weidan Ji, Yang Xu, Shuwen Shen, Yan Yan, Xuandong Huang, Junnian Zheng, Changqing Su

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1079-1089

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

Schammim Ray Amith, Jodi Marie Wilkinson, Shairaz Baksh, Larry Fliegel

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1262-1275

Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells Research Paper

Keita Shibuya, Masashi Okada, Shuhei Suzuki, Manabu Seino, Shizuka Seino, Hiroyuki Takeda, Chifumi Kitanaka

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 651-661

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer Research Paper

Wei-Yu Chen, Shih-Yang Liu, Yung-Sheng Chang, Juan Juan Yin, Hsiu-lien Yeh, Tarek H. Mouhieddine, Ola Hadadeh, Wassim Abou-Kheir, Yen-Nien Liu

Published Nov 25, 2014 · Vol. 6, No. 1 · pp. 441-457

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer Priority Research Paper

Frank P. Vendetti, Michael Topper, Peng Huang, Irina Dobromilskaya, Hariharan Easwaran, John Wrangle, Stephen B. Baylin, J. T. Poirier, Charles M. Rudin

Published Nov 25, 2014 · Vol. 6, No. 1 · pp. 56-70

Keywords: epigenetic, azacitidine, entinostat, priming, chemosensitivity, non-small cell lung cancer (NSCLC)

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Hon-Yi Lin, Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Tze-Ta Huang, Chih-En Tseng, Liang-Yu Shih, Ru-Inn Lin, Jora M.J. Lin, Yi-Hui Lai, Chia-Bin Chang, Feng-Chun Hsu, Liang-Cheng Chen, Shiang-Jiun Tsai, Yu-Chieh Su, Szu-Chi Li, Hung-Chih Lai, Wen-Lin Hsu, Dai-Wei Liu, Chien-Kuo Tai, Shu-Fen Wu, Michael W.Y. Chan

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 915-934

Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Research Paper

Igor Vujic, Martina Sanlorenzo, Christian Posch, Rosaura Esteve-Puig, Adam J. Yen, Andrew Kwong, Aaron Tsumura, Ryan Murphy, Klemens Rappersberger, Susana Ortiz-Urda

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 969-978

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Takuya Nakamura, Satoru Shinriki, Hirofumi Jono, Jianying Guo, Mitsuharu Ueda, Mitsuhiro Hayashi, Satoshi Yamashita, Andries Zijlstra, Hideki Nakayama, Akimitsu Hiraki, Masanori Shinohara, Yukio Ando

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 1008-1019

Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer Research Paper

Fengjin Zhao, Tianxin Lin, Wang He, Jinli Han, Dingjun Zhu, Kaishun Hu, Weicong Li, Zaosong Zheng, Jian Huang, Wenlian Xie

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 1064-1078

Afatinib circumvents multidrug resistance via dually inhibiting ATP binding cassette subfamily G member 2 in vitro and in vivo Research Paper

Xiao-kun Wang, Kenneth Kin Wah To, Li-yan Huang, Jing-hong Xu, Ke Yang, Fang Wang, Zhen-cong Huang, Sheng Ye, Li-wu Fu

Published Nov 24, 2014 · Vol. 5, No. 23 · pp. 11971-11985

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

Galina Kochneva, Evgeniy Zonov, Antonina Grazhdantseva, Anastasiya Yunusova, Galina Sibolobova, Evgeniy Popov, Oleg Taranov, Sergei Netesov, Peter Chumakov, Elena Ryabchikova

Published Nov 19, 2014 · Vol. 5, No. 22 · pp. 11269-11282

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation Priority Research Paper

Ulrike Keitel, Andreas Scheel, JÃ¼rgen Thomale, Rovena Halpape, Silke KaulfuÃŸ, Christina Scheel, Matthias Dobbelstein

Published Nov 17, 2014 · Vol. 5, No. 23 · pp. 11778-11791

Keywords: Bcl-xL, Chemo-resistance, Epithelial Mesenchymal Transition, Apoptosis, BH3-mimetic

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells Research Paper

Martin Puhr, Julia Hoefer, Hannes Neuwirt, Iris E. Eder, Johann Kern, Georg SchÃ¤fer, Stephan Geley, Isabel Heidegger, Helmut Klocker, Zoran Culig

Published Nov 17, 2014 · Vol. 5, No. 23 · pp. 12043-12056

Keywords: prostate cancer, PIAS1, docetaxel, chemotherapy resistance, apoptosis

Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia Clinical Research Papers

Rene Cortese, Isaac Almendros, Yang Wang, David Gozal

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 556-569

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1 Research Paper

Yi-Fang Chang, Ya-Fen Hsu, Pei-Ting Chiu, Wei-Jan Huang, Shiu-Wen Huang, George Ou, Joen-Rong Sheu, Ming-Jen Hsu

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 85-100

MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis Research Paper

Ming-Yi Ho, Chi-Ming Liang, Shu-Mei Liang

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 381-393

Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A Research Paper

Hongxia Chen, Lingmin Li, Shaojun Wang, Yupeng Lei, Qi Ge, Nonghua Lv, Xiaodong Zhou, Changyan Chen

Published Nov 15, 2014 · Vol. 5, No. 23 · pp. 11873-11885

Keywords: miR-126, gastric cancer, angiogenesis, VEGF, Akt/m-TOR phosphorylation

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Francesca Pretto, Carmen Ghilardi, Michele Moschetta, Andrea Bassi, Alessandra Rovida, Valentina Scarlato, Laura Talamini, Fabio Fiordaliso, Cinzia Bisighini, Giovanna Damia, Maria Rosa Bani, Rosanna Piccirillo, Raffaella Giavazzi

Published Nov 15, 2014 · Vol. 6, No. 5 · pp. 3043-3054

Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells Research Paper

Wangbing Chen, Jianjun Lu, Yu Qin, Jingshu Wang, Yun Tian, Dingbo Shi, Shusen Wang, Yao Xiao, Meng Dai, Lu Liu, Guo Wei, Taihua Wu, Bilian Jin, Xiangsheng Xiao, Tie-Bang Kang, Wenlin Huang, Wuguo Deng

Published Nov 13, 2014 · Vol. 5, No. 23 · pp. 11909-11923

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Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells Research Paper

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer Research Paper

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer Priority Research Paper

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Research Paper

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer Research Paper

Afatinib circumvents multidrug resistance via dually inhibiting ATP binding cassette subfamily G member 2 in vitro and in vivo Research Paper

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation Priority Research Paper

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells Research Paper

Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia Clinical Research Papers

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1 Research Paper

MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis Research Paper

Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A Research Paper

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

The Na+/H+ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells Research Paper

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer Research Paper

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer Priority Research Paper

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Research Paper

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer Research Paper

Afatinib circumvents multidrug resistance via dually inhibiting ATP binding cassette subfamily G member 2 in vitro and in vivo Research Paper

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation Priority Research Paper

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells Research Paper

Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia Clinical Research Papers

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1 Research Paper

MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis Research Paper

Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A Research Paper

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells Research Paper

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper