The Oncosearch | Oncotarget

Two hits are better than one: synergistic anticancer activity of Î±-helical peptides and doxorubicin/epirubicin Research Paper

Jing Zhao, Yibing Huang, Dong Liu, Yuxin Chen

Published Dec 19, 2014 · Vol. 6, No. 3 · pp. 1769-1778

Keywords: Anticancer peptides, doxorubicin/epirubicin, synergy, mechanism of action, xenograft model

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells Research Paper

Antonella Cusimano, Roberto Puleio, Natale D'Alessandro, Guido R. Loria, James A. McCubrey, Giuseppe Montalto, Melchiorre Cervello

Published Dec 19, 2014 · Vol. 6, No. 3 · pp. 1707-1722

Keywords: HCC, AKT, mTOR, SC66, anoikis.

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Hisato Kawakami, Isamu Okamoto, Kimio Yonesaka, Kunio Okamoto, Kiyoko Shibata, Yume Shinkai, Haruka Sakamoto, Michiko Kitano, Takao Tamura, Kazuto Nishio, Kazuhiko Nakagawa

Published Dec 19, 2014 · Vol. 5, No. 23 · pp. 11847-11856

Keywords: colorectal cancer, heregulin, resistance, cetuximab, patritumab

CD117+ cells in the circulation are predictive of advanced prostate cancer Clinical Research Papers

Bethany A. Kerr, Ranko Miocinovic, Armine K. Smith, Xiaoxia Z. West, Katherine E. Watts, Amanda W. Alzayed, Joseph C. Klink, Maria C. Mir, Tiffany Sturey, Donna E. Hansel, Warren D. Heston, Andrew J. Stephenson, Eric A. Klein, Tatiana V. Byzova

Published Dec 17, 2014 · Vol. 6, No. 3 · pp. 1889-1897

Keywords: CD117/c-kit, CD133, prostate cancer, tumor progression

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper

Guobing Li, Jing Zhou, Amit Budhraja, Xiaoye Hu, Yibiao Chen, Qi Cheng, Lei Liu, Ting Zhou, Ping Li, Ehu Liu, Ning Gao

Published Dec 16, 2014 · Vol. 6, No. 3 · pp. 1834-1849

Keywords: Cofilin, Drp1, mitochondrial fission, erucin, apoptosis

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Chenchen Wang, Quan Zhou, Xiaofeng Wang, Xiongyan Wu, Xuehua Chen, Jianfang Li, Zhenggang Zhu, Bingya Liu, Liping Su

Published Dec 15, 2014 · Vol. 6, No. 3 · pp. 1779-1789

Keywords: TLR7, Treg cells, Immune suppression, Anti-tumor effect

Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer Research Paper

Dong Lin, Xin Dong, Kendric Wang, Alexander W. Wyatt, Francesco Crea, Hui Xue, Yuwei Wang, Rebecca Wu, Robert H. Bell, Anne Haegert, Sonal Brahmbhatt, Antonio Hurtado-Coll, Peter W. Gout, Ladan Fazli, Martin E. Gleave, Colin C. Collins, Yuzhuo Wang

Published Dec 11, 2014 · Vol. 6, No. 3 · pp. 1806-1820

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Teeru Bihani, Scott A. Ezell, Brendon Ladd, Shaun E. Grosskurth, Anne Marie Mazzola, Mark Pietras, Corinne Reimer, Michael Zinda, Stephen Fawell, Celina M. Dâ€™Cruz

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2407-2420

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

Ting-Ting Chao, Cheng-Yi Wang, Yen-Lin Chen, Chih-Cheng Lai, Fang-Yu Chang, Yi-Ting Tsai, Chung-Hao H. Chao, Chung-Wai Shiau, Yuh-Chin T. Huang, Chong-Jen Yu, Kuen-Feng Chen

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2164-2179

Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma Research Paper

Xiaodong He, Jingjing Li, Weidong Guo, Wei Liu, Jia Yu, Wei Song, Lei Dong, Fang Wang, Shuangni Yu, Yi Zheng, Songsen Chen, Yan Kong, Changzheng Liu

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2302-2314

Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget Research Paper

Ya-Qi Qiu, Cheng-Wei Yang, Yue-Zhi Lee, Ruey-Bing Yang, Chih-Hao Lee, Hsing-Yu Hsu, Chien-Chung Chang, Shiow-Ju Lee

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2148-2163

FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells Research Paper

Wen-Tai Chiu, Yu-Fang Huang, Huei-Yu Tsai, Chien-Chin Chen, Chang-Hwa Chang, Soon-Cen Huang, Keng-Fu Hsu, Cheng-Yang Chou

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2349-2365

Î±-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma Research Paper

Katharina Teiluf, Christof Seidl, Birgit Blechert, Florian C. Gaertner, Klaus-Peter Gilbertz, Vanesa Fernandez, Florian Bassermann, Jan Endell, Rainer Boxhammer, Stephane Leclair, Mario Vallon, Michaela Aichler, Annette Feuchtinger, Frank Bruchertseifer, Alfred Morgenstern, Markus Essler

Published Dec 10, 2014 · Vol. 6, No. 7 · pp. 4692-4703

Functional repair of p53 mutation in colorectal cancer cells using trans-splicing Research Paper

Xingxing He, Jiazhi Liao, Fang Liu, Junwei Yan, Jingjun Yan, Haitao Shang, Qian Dou, Ying Chang, Jusheng Lin, Yuhu Song

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2034-2045

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

Michael Ehrhardt, Rogerio B. Craveiro, Martin I. Holst, Torsten Pietsch, Dagmar Dilloo

Published Dec 6, 2014 · Vol. 6, No. 2 · pp. 802-813

Keywords: medulloblastoma, GDC-0941, PI3K inhibitor, targeted therapy, c-myc

A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor Research Paper

Odile Gayet, Celine Loncle, Pauline Duconseil, Marine Gilabert, Maria Belen Lopez, Vincent Moutardier, Olivier Turrini, Ezequiel Calvo, Jacques Ewald, Marc Giovannini, Mohamed Gasmi, Erwan Bories, Marc Barthet, Mehdi Ouaissi, Anthony Goncalves, Flora Poizat, Jean Luc Raoul, Veronique Secq, Stephane Garcia, Patrice Viens, Nelson Dusetti, Juan Iovanna

Published Dec 3, 2014 · Vol. 6, No. 2 · pp. 746-754

Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma Research Paper

Chunyan Li, Gang Meng, Lei Su, Aiping Chen, Mao Xia, Chun Xu, Decai Yu, Aiqin Jiang, Jiwu Wei

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1544-1555

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Two hits are better than one: synergistic anticancer activity of Î±-helical peptides and doxorubicin/epirubicin Research Paper

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

CD117+ cells in the circulation are predictive of advanced prostate cancer Clinical Research Papers

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer Research Paper

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma Research Paper

Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget Research Paper

FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells Research Paper

Î±-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma Research Paper

Functional repair of p53 mutation in colorectal cancer cells using trans-splicing Research Paper

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor Research Paper

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma Research Paper

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Two hits are better than one: synergistic anticancer activity of Î±-helical peptides and doxorubicin/epirubicin Research Paper

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

CD117+ cells in the circulation are predictive of advanced prostate cancer Clinical Research Papers

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer Research Paper

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma Research Paper

Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget Research Paper

FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells Research Paper

Î±-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma Research Paper

Functional repair of p53 mutation in colorectal cancer cells using trans-splicing Research Paper

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor Research Paper

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma Research Paper

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma Research Paper

Î±-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma Research Paper