The Oncosearch | Oncotarget

Retraction: Hsa-miR-875-5p exerts tumor suppressor function through down-regulation of EGFR in colorectal carcinoma (CRC) Retraction

Tiening Zhang, Xun Cai, Qi Li, Peng Xue, Zhixiao Chen, Xiao Dong, Ying Xue

Published Jul 11, 2024

How to deal with runaway metastatic disease? Editorial

Justine Paris, Guilhem Bousquet

Published Jul 5, 2024 · Vol. 15, No. 1 · pp. 466-467

Keywords: metastatic disease, PROM2, biomarker, tumor growth models

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Chantal L. Duurland, Thijs de Gunst, Harm C. den Boer, Marion T.J. van den Bosch, Bryony J. Telford, Rogier M. Vos, Xiaolei Xie, Mingfa Zang, Fang Wang, Yingying Shao, Xiaoyu An, Jingjing Wang, Jie Cai, Ludovic Bourré, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot, Sanaz Yahyanejad

Published Jul 4, 2024 · Vol. 15, No. 1 · pp. 470-485

Keywords: miR-193a-3p, microRNA mimic, T cell mediated immunity, immunogenic cell death, cancer

Rapid but nondurable response of a BRAF exon 15 double-mutated spindle cell sarcoma to a combination of BRAF and MEK inhibitors Case Report

Kseniya Sinichenkova, Iliya Sidorov, Nataliya Kriventsova, Dmitriy Konovalov, Ruslan Abasov, Nataliya Usman, Alexander Karachunskiy, Galina Novichkova, Dmitriy Litvinov, Alexander Druy

Published Jul 1, 2024 · Vol. 15, No. 1 · pp. 493-500

Keywords: undifferentiated sarcoma, BRAF V600E mutation, low grade spindle cell sarcoma, abdominal cocoon

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Alexandra Jackovich, Barbara J. Gitlitz, Justin Wayne Wong Tiu-lim, Vinay Duddalwar, Kevin George King, Anthony B. El-Khoueiry, Jacob Stephen Thomas, Denice Tsao-Wei, David I. Quinn, Parkash S. Gill, Jorge J. Nieva

Published Jun 29, 2024 · Vol. 15, No. 1 · pp. 444-458

Keywords: EphrinB2, EphB4, HNSCC, pembrolizumab, HPV-negative

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Jun Zhang, Lanlan Zhou, Shuai Zhao, Wafik S. El-Deiry

Published Jun 24, 2024 · Vol. 15, No. 1 · pp. 424-438

Keywords: TAS102, regorafenib, ERK1/2, angiogenesis, microvessel density

Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer Editorial

S.H. Tolmeijer, E. Boerrigter, N.P. Van Erp, Niven Mehra

Published Jun 19, 2024 · Vol. 15, No. 1 · pp. 421-423

Keywords: ctDNA, prostate cancer, liquid biopsy, biomarker, androgen receptor pathway inhibitors

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

Aashirwad Shahi, Dawit Kidane

Published Jun 12, 2024 · Vol. 15, No. 1 · pp. 392-399

Keywords: amino acid depletion, DNA damage, DNA repair, Immunotherapy, tumor immunity

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma Research Paper

Kazuhiro Kitajima, Kozo Kuribayashi, Toshiyuki Minami, Hiroyuki Yokoyama, Akifumi Nakamura, Masaki Hashimoto, Takashi Kijima, Seiki Hasegawa, Hayato Kaida, Koichiro Yamakado

Published Jun 11, 2024 · Vol. 15, No. 1 · pp. 408-417

Keywords: mesothelioma, immunotherapy, FDG (fluorodeoxyglucose), PET-CT (positron emission tomography-computed tomography), immunotherapy-modified PERCIST (positron emission tomography response criteria in solid tumors)

Leveraging gold nanostars for precision laser interstitial thermal therapy Editorial

Aden P. Haskell-Mendoza, Ethan S. Srinivasan, Tuan Vo-Dinh, Peter E. Fecci

Published Jun 6, 2024 · Vol. 15, No. 1 · pp. 389-391

Keywords: laser interstitial thermal therapy, gold nanostars, brain tumors, thermal ablation, immunotherapy

When does a melanoma metastasize? Implications for management Research Perspective

John F. Thompson, Gabrielle J. Williams

Published Jun 4, 2024 · Vol. 15, No. 1 · pp. 374-378

Keywords: melanoma, metastasis, time, adjuvant systemic therapy, tumor doubling time

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

Laurence Booth, Jane L. Roberts, Ivan Spasojevic, Kaitlyn C. Baker, Andrew Poklepovic, Cameron West, John M. Kirkwood, Paul Dent

Published May 9, 2024 · Vol. 15, No. 1 · pp. 328-344

Keywords: autophagy, ER stress, GZ17-6.02, doxorubicin, afatinib, neratinib

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Lulzim Shkreta, Johanne Toutant, Aurélie Delannoy, David Durantel, Anna Salvetti, Sophie Ehresmann, Martin Sauvageau, Julien A. Delbrouck, Alice Gravel-Trudeau, Christian Comeau, Caroline Huard, Jasmin Coulombe-Huntington, Mike Tyers, David Grierson, Pierre-Luc Boudreault, Benoit Chabot

Published May 9, 2024 · Vol. 15, No. 1 · pp. 313-325

Keywords: CLK kinases inhibitors, EMT, antiviral immune response, microtubules, metastasis

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

Shengliang Zhang, Wafik S. El-Deiry

Published Apr 29, 2024 · Vol. 15, No. 1 · pp. 275-284

Keywords: SARS-COV2 spike, p53, MDM2, chemotherapy, cancer

Correction: Analytical validation of NeXT Personal^®, an ultra-sensitive personalized circulating tumor DNA assay Correction

Josette Northcott, Gabor Bartha, Jason Harris, Conan Li, Fabio C.P. Navarro, Rachel Marty Pyke, Manqing Hong, Qi Zhang, Shuyuan Ma, Tina X. Chen, Janet Lai, Nitin Udar, Juan-Sebastian Saldivar, Erin Ayash, Joshua Anderson, Jiang Li, Tiange Cui, Tu Le, Ruthie Chow, Randy Jerel Velasco, Chris Mallo, Rose Santiago, Robert C. Bruce, Laurie J. Goodman, Yi Chen, Dan Norton, Richard O. Chen, John M. Lyle

Published Apr 23, 2024 · Vol. 15, No. 1 · pp. 407-407

Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia Research Paper

Simonetta I. Gaumond, Rama Abdin, Joel Costoya, Andrew V. Schally, Joaquin J. Jimenez

Published Mar 30, 2024 · Vol. 15, No. 1 · pp. 248-254

Keywords: leukemia, AML, resistance, growth hormone-releasing hormone, MIA-602

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

Takahiro Ohashi, Sayuri Terada, Shinsuke Hiramoto, Yuko Nagata, Hirokazu Suzuki, Hitoshi Miyashita, Tetsuo Sasaki, Yasukatsu Tsukada, Keiko Fukushima

Published Mar 29, 2024 · Vol. 15, No. 1 · pp. 256-274

Keywords: bispecific antibody, Cys1m, IgM, lymphoma, cynomolgus monkey

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Haven R. Garber, Sreyashi Basu, Sonali Jindal, Zhong He, Khoi Chu, Akshara Singareeka Raghavendra, Clinton Yam, Lumarie Santiago, Beatriz E. Adrada, Padmanee Sharma, Elizabeth A. Mittendorf, Jennifer K. Litton

Published Mar 2, 2024 · Vol. 15, No. 1 · pp. 238-247

Keywords: breast cancer, ER positive, immunotherapy, neoadjuvant chemotherapy, tumor microenvironment

Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management Research Paper

Scott Strum, Mark Vincent, Meghan Gipson, Eric McArthur, Daniel Breadner

Published Feb 28, 2024 · Vol. 15, No. 1 · pp. 381-388

Keywords: tumor marker, biomarker, lung cancer, NSCLC, translational research

Analytical validation of NeXT Personal^®, an ultra-sensitive personalized circulating tumor DNA assay Research Paper

Josette Northcott, Gabor Bartha, Jason Harris, Conan Li, Fabio C.P. Navarro, Rachel Marty Pyke, Manqing Hong, Qi Zhang, Shuyuan Ma, Tina X. Chen, Janet Lai, Nitin Udar, Juan-Sebastian Saldivar, Erin Ayash, Joshua Anderson, Jiang Li, Tiange Cui, Tu Le, Ruthie Chow, Randy Jerel Velasco, Chris Mallo, Rose Santiago, Robert C. Bruce, Laurie J. Goodman, Yi Chen, Dan Norton, Richard O. Chen, John M. Lyle

Published Feb 21, 2024 · Vol. 15, No. 1 · pp. 200-218

Keywords: circulating tumor DNA, whole genome sequencing, molecular residual disease, tumor-informed assay, analytical validation

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Retraction: Hsa-miR-875-5p exerts tumor suppressor function through down-regulation of EGFR in colorectal carcinoma (CRC) Retraction

How to deal with runaway metastatic disease? Editorial

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Rapid but nondurable response of a BRAF exon 15 double-mutated spindle cell sarcoma to a combination of BRAF and MEK inhibitors Case Report

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer Editorial

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma Research Paper

Leveraging gold nanostars for precision laser interstitial thermal therapy Editorial

When does a melanoma metastasize? Implications for management Research Perspective

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

Correction: Analytical validation of NeXT Personal^®, an ultra-sensitive personalized circulating tumor DNA assay Correction

Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia Research Paper

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management Research Paper

Analytical validation of NeXT Personal^®, an ultra-sensitive personalized circulating tumor DNA assay Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Retraction: Hsa-miR-875-5p exerts tumor suppressor function through down-regulation of EGFR in colorectal carcinoma (CRC) Retraction

How to deal with runaway metastatic disease? Editorial

INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death Research Paper

Rapid but nondurable response of a BRAF exon 15 double-mutated spindle cell sarcoma to a combination of BRAF and MEK inhibitors Case Report

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper

Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer Editorial

Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective

Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma Research Paper

Leveraging gold nanostars for precision laser interstitial thermal therapy Editorial

When does a melanoma metastasize? Implications for management Research Perspective

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response Research Paper

Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure Research Paper

Correction: Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay Correction

Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia Research Paper

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer Research Paper

Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management Research Paper

Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay Research Paper

Correction: Analytical validation of NeXT Personal^®, an ultra-sensitive personalized circulating tumor DNA assay Correction

Analytical validation of NeXT Personal^®, an ultra-sensitive personalized circulating tumor DNA assay Research Paper