The Oncosearch | Oncotarget

Retraction: miR-101 targeting ZFX suppresses tumor proliferation and metastasis by regulating the MAPK/Erk and Smad pathways in gallbladder carcinoma Retraction

Run-Fa Bao, Yi-Jun Shu, Yun-Ping Hu, Xu-An Wang, Fei Zhang, Hai-Bin Liang, Yuan-Yuan Ye, Huai-Feng Li, Shan-Shan Xiang, Hao Weng, Yang Cao, Xiang-Song Wu, Mao-Lan Li, Wen-guang Wu, Yi-Jian Zhang, Lin Jiang, Qian Dong, Ying-Bin Liu

Published Dec 2, 2025 · Vol. 16, No. 1 · pp. 859-859

Machine learning-based survival prediction in colorectal cancer combining clinical and biological features Research Paper

Lucas M. Vieira, Natasha A.N. Jorge, João B. Sousa, João C. Setubal, Peter F. Stadler, Maria E.M.T. Walter

Published Dec 2, 2025 · Vol. 16, No. 1 · pp. 834-847

Keywords: colorectal cancer, machine learning, feature selection, non-coding RNAs, genes

Mechanism of anticancer action of bifidobacterium: Insights from gut microbiota Review

Hoang Do, Esther Asiamah, Mayanijesu Olorife, Arathi Pillai, Sakshi Patel, Ponniah Selvakumar, Sidhartha D. Ray, Ashakumary Lakshmikuttyamma

Published Nov 6, 2025 · Vol. 16, No. 1 · pp. 818-833

Keywords: cancer, gut microbiota, bifidobacterium

Correction: Enhanced proteasomal activity is essential for long term survival and recurrence of innately radiation resistant residual glioblastoma cells Correction

Jacinth Rajendra, Keshava K. Datta, Sheikh Burhan Ud Din Farooqee, Rahul Thorat, Kiran Kumar, Nilesh Gardi, Ekjot Kaur, Jyothi Nair, Sameer Salunkhe, Ketaki Patkar, Sanket Desai, Jayant Sastri Goda, Aliasgar Moiyadi, Amit Dutt, Prasanna Venkatraman, Harsha Gowda, Shilpee Dutt

Published Nov 6, 2025 · Vol. 16, No. 1 · pp. 791-792

A personal perspective of patient-centred clinical trials Research Perspective

Trevor Tyne, Elizabeth Ivimey, Leanne Duggan, Jia Liu

Published Nov 5, 2025 · Vol. 16, No. 1 · pp. 808-812

Keywords: precision oncology, patient-centric care, clinical trials, tumor agnostic, drug development

LRIG1-3 in gliomas: LRIG1 protein expression decreased in higher grade gliomas Research Paper

Marlene Happe, Saskia Kuhl, Lukas Görtz, Roland Goldbrunner, Marco Timmer

Published Oct 27, 2025 · Vol. 16, No. 1 · pp. 793-807

Keywords: glioma, glioblastoma, LRIG1, LRIG2, LRIG3

Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Ashley C. Dodd, Nitin R. Wadhwani, Alison Lehane, Rom Brown, Kyle L. MacQuarrie, Seth D. Goldstein, Timothy B. Lautz

Published Oct 13, 2025 · Vol. 16, No. 1 · pp. 759-767

Keywords: folate receptor, fluorescent-guided surgery, pediatric tumors, pafolacianine, RNA sequencing

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields Research Paper

Hugo Jimenez, Denise Gibo, Sambad Sharma, Michael Pennison, Lance D. Miller, Minghui Wang, Kimberly Sheffield, Liyue Zhang, Allan Johansen, Preeya Achari, Callum Mcgrath, Sean Lester, Jason Tang, Kojo Agyemang, Annette Johnson, Christopher T. Whitlow, Michael Chan, Kounosuke Watabe, Ralph D’Agostino Jr., Janaka Liyanage, Asfar Azmi, Geoffrey Barger, Alexandre Barbault, Glenn J. Lesser, Waldemar Debinski, Boris C. Pasche

Published Oct 2, 2025 · Vol. 16, No. 1 · pp. 741-757

Keywords: amplitude-modulated radiofrequency electromagnetic fields, glioblastoma, TheraBionic, CACNA1H, Ca_v3.2

ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response Research Paper

Kyle R. Cron, Ping Fang, Oanh Pham, Julie Janes, John Brandenburg, William Lu, Jonathan Zhu, Bret Peterson, Sara Tribble, Haixing Kehoe, Anastasia Makarova, Alex Iannello, Jean Chan, Justin Skoble, Hailey He, Chris Rae, Christopher D. Thanos, Akshata R. Udyavar

Published Oct 2, 2025 · Vol. 16, No. 1 · pp. 721-740

Keywords: tumor microenvironment, bacterial vector, myeloid cells, STING, IL-15

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

Jacob Haagsma, Yudith Ramos Valdes, Xuejin Ou, Rasheduzzaman Rashu, S.M. Mansour Haeryfar, Jim Petrik, Trevor G. Shepherd

Published Sep 16, 2025 · Vol. 16, No. 1 · pp. 697-718

Keywords: high-grade serous ovarian carcinoma, orthotopic models, inflammation, microenvironment

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Kristen Kwong, Yue Pan, Jacqueline Morales, Matthew Watson, David V. Allegakoen, Alex G. Lee, Trever G. Bivona, Peter Wipf, Christopher J. Guerriero, Jeffrey L. Brodsky, Amit J. Sabnis

Published Aug 23, 2025 · Vol. 16, No. 1 · pp. 681-696

Keywords: protein homeostasis, rhabdomyosarcoma, unfolded protein response, preclinical therapeutics, p97

The SCD1 inhibitor aramchol interacts with regorafenib to kill GI tumor cells in vitro and in vivo Research Paper

Laurence Booth, Michael R. Booth, Jane L. Roberts, Yang Yue, Emily Kinsey, Andrew Poklepovic, David Boone, L. Ashley Cowhart, Allen Baharaff, Paul Dent

Published Aug 14, 2025 · Vol. 16, No. 1 · pp. 662-678

Keywords: macroautophagy, flux, ER stress, aramchol, regorafenib

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Valeriy Domenyuk, Kasey Benson, Peggy Carter, Daniel Magee, Jian Zhang, Nitin Bhardwaj, Hongseok Tae, James Wacker, Foram Rathi, Siobhan Miick, Aastha Kohli, Joshua Carroll, Lori Cuyugan, Evelyn Perez, Wayeesha Zhang, John Collins, Patrick Kennedy, Jeremy Ellis, Adam Stark, Andrey Loskutov, Brittany Cuttone, Blake Taylor, Rebecca Feldman, Jeff Swenson, David Bryant, Robert Hahn-Lowry, Raunaq Kaushal, Jennifer R. Ribeiro, Jim Abraham, Milan Radovich, George W. Sledge, Matthew Oberley, David Spetzler

Published Aug 6, 2025 · Vol. 16, No. 1 · pp. 642-659

Keywords: companion diagnostic, molecular profiling, solid tumors, precision oncology, next-generation sequencing

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Aiden Deacon, Ava Gustafson, Allison Makovec, Ella Boytim, Gabriella von Dohlen, David Moline, Elin Kairies, Sam Kellen, Khalid Ishani, Megan L. Ludwig, Emily John, Alexis Anike, Hai Dang Nguyen, Scott M. Dehm, Justin M. Drake, Emmanuel S. Antonarakis, Justin Hwang

Published Jul 19, 2025 · Vol. 16, No. 1 · pp. 606-620

Keywords: RSPO2, prostate cancer, Wnt signaling, genomics, therapeutics

Comprehensive genomic profiling of over 10,000 advanced solid tumors Research Paper

Jean-Paul De La O, Jess R. Hoag, Angela K. Deem, Min Wang, Arthur Starodynov, Sameer S. Udhane, Janine R. LoBello, Nishitha Therala, David W. Hall, Gargi D. Basu, Frederick L. Baehner

Published Jul 19, 2025 · Vol. 16, No. 1 · pp. 587-603

Keywords: solid tumors, comprehensive genomic profiling, matched therapy, gene fusions, limit of detection

Extracorporeal blood filtration leading to tumor growth arrest and reduced analgesic requirements in Stage IV poorly differentiated pancreatic adenocarcinoma: A case report Case Report

Susanna Ulahannan, Peyton Smith, Jennifer Rios, Lakhmir Chawla

Published Jul 18, 2025 · Vol. 16, No. 1 · pp. 582-586

Keywords: extracorporeal blood filtration, circulating tumor cells, metastatic pancreatic cancer, seraph 100, OncoBind

Statins exhibit anti-tumor potential by modulating Wnt/β-catenin signaling in colorectal cancer Research Paper

Sneha Tripathi, Ekta Gupta, Rutika Naik, Satyajeet Khare, Rafeeq Mir, Siddhesh Kamat, Sanjeev Galande

Published Jul 12, 2025 · Vol. 16, No. 1 · pp. 562-581

Keywords: colorectal cancer, statins, SATB1, Wnt/β-catenin signaling, tumor-suppressive phenotype

A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment Research Paper

Maja Buszko, Madalyn Jones, Sruthi Chempati, Lyra Morina, Kirstin Ward, Habtom Habte, Michael Dziegielewski, Ethan M. Shevach

Published Jun 30, 2025 · Vol. 16, No. 1 · pp. 545-558

Keywords: T_reg, CD25, TME, mAb, GVHD

Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer Research Paper

Shailender S. Chauhan, Andres D. Vizzerra, Hope Liou, Caitlyn E. Flores, Ashley J. Snider, Justin M. Snider, Noel A. Warfel

Published Jun 18, 2025 · Vol. 16, No. 1 · pp. 532-544

Keywords: hypoxia, lipid droplets, ferroptosis, resistance, prostate

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Shreya Shyamsunder, Zhixin Lu, Vinita Takiar, Susan E. Waltz

Published Jun 16, 2025 · Vol. 16, No. 1 · pp. 508-530

Keywords: EGFR, RTKs, breast cancer, head and neck cancer, resistance mechanisms

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Retraction: miR-101 targeting ZFX suppresses tumor proliferation and metastasis by regulating the MAPK/Erk and Smad pathways in gallbladder carcinoma Retraction

Machine learning-based survival prediction in colorectal cancer combining clinical and biological features Research Paper

Mechanism of anticancer action of bifidobacterium: Insights from gut microbiota Review

Correction: Enhanced proteasomal activity is essential for long term survival and recurrence of innately radiation resistant residual glioblastoma cells Correction

A personal perspective of patient-centred clinical trials Research Perspective

LRIG1-3 in gliomas: LRIG1 protein expression decreased in higher grade gliomas Research Paper

Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields Research Paper

ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response Research Paper

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

The SCD1 inhibitor aramchol interacts with regorafenib to kill GI tumor cells in vitro and in vivo Research Paper

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Comprehensive genomic profiling of over 10,000 advanced solid tumors Research Paper

Extracorporeal blood filtration leading to tumor growth arrest and reduced analgesic requirements in Stage IV poorly differentiated pancreatic adenocarcinoma: A case report Case Report

Statins exhibit anti-tumor potential by modulating Wnt/β-catenin signaling in colorectal cancer Research Paper

A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment Research Paper

Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer Research Paper

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Retraction: miR-101 targeting ZFX suppresses tumor proliferation and metastasis by regulating the MAPK/Erk and Smad pathways in gallbladder carcinoma Retraction

Machine learning-based survival prediction in colorectal cancer combining clinical and biological features Research Paper

Mechanism of anticancer action of bifidobacterium: Insights from gut microbiota Review

Correction: Enhanced proteasomal activity is essential for long term survival and recurrence of innately radiation resistant residual glioblastoma cells Correction

A personal perspective of patient-centred clinical trials Research Perspective

LRIG1-3 in gliomas: LRIG1 protein expression decreased in higher grade gliomas Research Paper

Widespread folate receptor expression in pediatric and adolescent solid tumors - opportunity for intraoperative visualization with the novel fluorescent agent pafolacianine Research Paper

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields Research Paper

ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response Research Paper

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

The SCD1 inhibitor aramchol interacts with regorafenib to kill GI tumor cells in vitro and in vivo Research Paper

Clinical and analytical validation of MI Cancer Seek®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer Research Paper

Comprehensive genomic profiling of over 10,000 advanced solid tumors Research Paper

Extracorporeal blood filtration leading to tumor growth arrest and reduced analgesic requirements in Stage IV poorly differentiated pancreatic adenocarcinoma: A case report Case Report

Statins exhibit anti-tumor potential by modulating Wnt/β-catenin signaling in colorectal cancer Research Paper

A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment Research Paper

Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer Research Paper

Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms Review

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper