The Oncosearch | Oncotarget

Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice Research Paper

Harshul Pandit, Yan Li, Qianqian Zheng, Wei Guo, Youxi Yu, Suping Li, Robert C.G. Martin

Published Jan 17, 2020 · Vol. 11, No. 22 · pp. 2047-2060

Keywords: hepatocellular carcinoma, Wnt/β-catenin signaling, cancer stem cells, epithelial cell adhesion molecule (EpCAM), tumor-initiating cells

Correction: Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo Correction

Songping Zheng, Yongzhong Cheng, Yan Teng, Xiaoxiao Liu, Ting Yu, Yi Wang, Jiagang Liu, Yuzhu Hu, Cong Wu, Xiang Wang, Yanhui Liu, Chao You, Xiang Gao, Yuquan Wei

Published Jan 16, 2020

Circulating tumor DNA analysis in the era of precision oncology Review

Rabih Said, Nicolas Guibert, Geoffrey R. Oxnard, Apostolia M. Tsimberidou

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 188-211

Keywords: circulating tumor DNA analysis, clinical trials, targeted therapy, genomic profiling

Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice Research Paper

Jabril R. Johnson, Justin B. Lack, Corinne A. Boulanger, Lauren E. Ragle, Gilbert H. Smith

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 161-174

Keywords: mitochondrial DNA, next-generation sequencing, clonal expansion, mammary cancer

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

Keisuke Taniuchi, Mitsunari Ogasawara

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 131-147

Keywords: RNA-binding protein, small nucleolar RNA, pancreatic cancer, cell invasion, metastasis

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Klara Fodor, Nikoletta Dobos, Andrew Schally, Zita Steiber, Gabor Olah, Eva Sipos, Lorant Szekvolgyi, Gabor Halmos

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 175-187

Keywords: uveal melanoma, luteinizing hormone-releasing hormone (LHRH) receptor, angiogenesis, MASPIN/SERPINB5, AEZS-108 (AN-152/Zoptarelin Doxorubicin Acetate)

Toxoplasma gondii GRA8-derived peptide immunotherapy improves tumor targeting of colorectal cancer Research Paper

Jae-Sung Kim, Daeun Lee, Donggyu Kim, Seok-Jun Mun, Euni Cho, Wooic Son, Chul-Su Yang

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 62-73

Keywords: Toxoplasma gondii GRA8 peptide, mitochondria, tumor-targeting, metabolism

Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Pharavee Jaiprasart, Samrita Dogra, Deepika Neelakantan, Bharat Devapatla, Sukyung Woo

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 99-114

Keywords: anti-VEGF resistance, angiogenesis, bevacizumab, next-generation sequencing (NGS), apelin

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

Elena Fountzilas, Vassiliki Kotoula, Georgia-Angeliki Koliou, Eleni Giannoulatou, Helen Gogas, Christos Papadimitriou, Ioannis Tikas, Jianhua Zhang, Kyriaki Papadopoulou, Flora Zagouri, Christos Christodoulou, Angelos Koutras, Thomas Makatsoris, Sofia Chrisafi, Helena Linardou, Ioannis Varthalitis, George Papatsibas, Evangelia Razis, Pavlos Papakostas, Epaminontas Samantas, Gerasimos Aravantinos, Dimitrios Bafaloukos, Paris Kosmidis, Anna Koumarianou, Amanda Psyrri, Georgios Pentheroudakis, Dimitrios Pectasides, Andrew Futreal, George Fountzilas, Apostolia M. Tsimberidou

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 1-14

Keywords: actionable gene, next-generation sequencing, pathogenic mutation, precision oncology, prognosis

PDLIM4/RIL-mediated regulation of Src and malignant properties of breast cancer cells Research Paper

Dmitry Sergeevich Kravchenko, Anna Evgenyevna Ivanova, Elizaveta Sergeevna Podshivalova, Stepan Petrovich Chumakov

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 22-30

Keywords: RIL, PDLIM4, Src, breast cancer, metastases

Evaluation of the genomic alterations in the androgen receptor gene during treatment with high-dose testosterone for metastatic castrate-resistant prostate cancer Research Paper

Marcus Moses, Ulkuhan Koksal, Elisa Ledet, Charlotte Manogue, Patrick Cotogno, Brian Lewis, Jodi Layton, A. Oliver Sartor, Pedro Barata

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 15-21

Keywords: castration-resistant prostate cancer, high-dose testosterone, next-generation sequencing, androgen receptor

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Kouki Okita, Shogo Okazaki, Shinya Uejima, Erina Yamada, Hiroki Kaminaka, Misa Kondo, Shiho Ueda, Ryo Tokiwa, Nami Iwata, Akitaka Yamasaki, Natsumi Hayashi, Dai Ogura, Kenji Hirotani, Toshiaki Yoshioka, Masahiro Inoue, Kazue Masuko, Takashi Masuko

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 31-45

Keywords: CDR, HER3, internalization, mAb, NRG1

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Hengyu Lu, Chen Liu, Hung Huynh, Thi Bich Uyen Le, Matthew LaMarche, Morvarid Mohseni, Jeffrey A. Engelman, Peter S. Hammerman, Giordano Caponigro, Huai-Xiang Hao

Published Jan 6, 2020

Keywords: SHP2, FGFR, resistance, feedback activation

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Farah Ballout, Alissar Monzer, Maamoun Fatfat, Hala El Ouweini, Miran A. Jaffa, Rana Abdel-Samad, Nadine Darwiche, Wassim Abou-Kheir, Hala Gali-Muhtasib

Published Jan 3, 2020 · Vol. 11, No. 31 · pp. 2959-2972

Keywords: thymoquinone, colorectal cancer stem cells, 5-Fluorouracil resistance, colonospheres, apoptosis

Dysregulation of adenosine kinase isoforms in breast cancer Research Paper

Bahar Shamloo, Nandita Kumar, Randall H. Owen, Jesica Reemmer, John Ost, R. Serene Perkins, Hai-Ying Shen

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7238-7250

Keywords: adenosine kinase, breast cancer, adenosine kinase isoforms, metastasis, proliferation

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Brandi L. Carofino, Kayla M. Dinshaw, Pui Yan Ho, Christophe Cataisson, Aleksandra M. Michalowski, Andrew Ryscavage, Addie Alkhas, Nathan W. Wong, Vishal Koparde, Stuart H. Yuspa

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7251-7275

Keywords: in situ hybridization, single-cell RNA-sequencing, stroma, miRNA, immune infiltration

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

Weng In Leong, Rachel Y. Ames, Jessica M. Haverkamp, Laura Torres, Janine Kline, Ashil Bans, Lauren Rocha, Marilena Gallotta, Cristiana Guiducci, Robert L. Coffman, Mary J. Janatpour

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7220-7237

Keywords: TLR9, SD-101, cyclophosphamide, immune therapy, innate immunity

Schwann cell reprogramming and lung cancer progression: a meta-analysis of transcriptome data Meta-Analysis

Victor Menezes Silva, Jessica Alves Gomes, Liliane Patrícia Gonçalves Tenório, Genilda Castro de Omena Neta, Karen da Costa Paixão, Ana Kelly Fernandes Duarte, Gabriel Cerqueira Braz da Silva, Ricardo Jansen Santos Ferreira, Bruna Del Vechio Koike, Carolinne de Sales Marques, Rafael Danyllo da Silva Miguel, Aline Cavalcanti de Queiroz, Luciana Xavier Pereira, Carlos Alberto de Carvalho Fraga

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7288-7307

Keywords: bioinformatic, lung squamous cell carcinoma, lung adenocarcinoma, neuroactive ligand-receptor interaction

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

Caroline K. Søgaard, Anala Nepal, Voin Petrovic, Animesh Sharma, Nina-Beate Liabakk, Tonje S. Steigedal, Marit Otterlei

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7185-7197

Keywords: APIM, multi-targeting therapy, signaling pathways, autophagy, cancer

Effects of neoadjuvant FOLFIRINOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper

Li Xie, Leizhou Xia, Ulla Klaiber, Milena Sachsenmaier, Ulf Hinz, Frank Bergmann, Oliver Strobel, Markus W. Büchler, John P. Neoptolemos, Franco Fortunato, Thilo Hackert

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7276-7287

Keywords: autophagy, cell death, stroma, neoadjuvant therapy, prognosis

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice Research Paper

Correction: Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo Correction

Circulating tumor DNA analysis in the era of precision oncology Review

Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice Research Paper

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Toxoplasma gondii GRA8-derived peptide immunotherapy improves tumor targeting of colorectal cancer Research Paper

Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

PDLIM4/RIL-mediated regulation of Src and malignant properties of breast cancer cells Research Paper

Evaluation of the genomic alterations in the androgen receptor gene during treatment with high-dose testosterone for metastatic castrate-resistant prostate cancer Research Paper

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Dysregulation of adenosine kinase isoforms in breast cancer Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

Schwann cell reprogramming and lung cancer progression: a meta-analysis of transcriptome data Meta-Analysis

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

Effects of neoadjuvant FOLFIRINOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice Research Paper

Correction: Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo Correction

Circulating tumor DNA analysis in the era of precision oncology Review

Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice Research Paper

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Toxoplasma gondii GRA8-derived peptide immunotherapy improves tumor targeting of colorectal cancer Research Paper

Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

PDLIM4/RIL-mediated regulation of Src and malignant properties of breast cancer cells Research Paper

Evaluation of the genomic alterations in the androgen receptor gene during treatment with high-dose testosterone for metastatic castrate-resistant prostate cancer Research Paper

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Dysregulation of adenosine kinase isoforms in breast cancer Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

Schwann cell reprogramming and lung cancer progression: a meta-analysis of transcriptome data Meta-Analysis

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

Effects of neoadjuvant FOLFIRINOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper