The Oncosearch | Oncotarget

Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells Research Paper

Masaya Jimbo, Fernando F. Blanco, Yu-Hung Huang, Aristeidis G. Telonis, Brad A. Screnci, Gabriela L. Cosma, Vitali Alexeev, Gregory E. Gonye, Charles J. Yeo, Janet A. Sawicki, Jordan M. Winter, Jonathan R. Brody

Published Jul 25, 2015 · Vol. 6, No. 29 · pp. 27312-27331

High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma Research Paper

Hongwei Guo, Yabin Cheng, Magdalena Martinka, Kevin McElwee

Published Jul 25, 2015 · Vol. 6, No. 28 · pp. 25484-25498

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

Mike I. Walton, Paul D. Eve, Angela Hayes, Alan T. Henley, Melanie R. Valenti, Alexis K. De Haven Brandon, Gary Box, Kathy J. Boxall, Matthew Tall, Karen Swales, Thomas P. Matthews, Tatiana McHardy, Michael Lainchbury, James Osborne, Jill E. Hunter, Neil D. Perkins, G. Wynne Aherne, John C. Reader, Florence I. Raynaud, Suzanne A. Eccles, Ian Collins, Michelle D. Garrett

Published Jul 22, 2015 · Vol. 7, No. 3 · pp. 2329-2342

Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy Research Paper

Sanchaika Gaur, Yunfei Wen, Jian H. Song, Nila U. Parikh, Lingegowda S. Mangala, Alicia M. Blessing, Cristina Ivan, Sherry Y. Wu, Andreas Varkaris, Yan Shi, Gabriel Lopez-Berestein, Daniel E. Frigo, Anil K. Sood, Gary E. Gallick

Published Jul 22, 2015 · Vol. 6, No. 30 · pp. 29161-29177

An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy Research Paper

Jian Xu, Xiu-Jun Liu, Liang Li, Sheng-Hua Zhang, Yi Li, Rui-Juan Gao, Yong-Su Zhen

Published Jul 20, 2015 · Vol. 6, No. 28 · pp. 26322-26334

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells Research Paper

Jessica L. Brusgard, Moran Choe, Saranya Chumsri, Keli Renoud, Alexander D. MacKerell Jr., Marius Sudol, Antonino Passaniti

Published Jul 20, 2015 · Vol. 6, No. 29 · pp. 28132-28150

Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model Research Paper

Devaraja Rajasekaran, Ayesha Siddiq, Jennifer L.S. Willoughby, Jessica M. Biagi, Lisa M. Christadore, Sarah A. Yunes, Rachel Gredler, Nidhi Jariwala, Chadia L. Robertson, Maaged A. Akiel, Xue-Ning Shen, Mark A. Subler, Jolene J. Windle, Scott E. Schaus, Paul B. Fisher, Ulla Hansen, Devanand Sarkar

Published Jul 17, 2015 · Vol. 6, No. 28 · pp. 26266-26277

Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo Research Paper

Andrew K. Kwegyir-Afful, Senthilmurugan Ramalingam, Puranik Purushottamachar, Vidya P. Ramamurthy, Vincent C. O. Njar

Published Jul 14, 2015 · Vol. 6, No. 29 · pp. 27440-27460

Deletion of Smad3 improves cardiac allograft rejection in mice Research Paper

Ying-ying Wang, Hong Jiang, Yu-cheng Wang, Xiao-ru Huang, Jun Pan, Chen Yang, Zhang-fei Shou, Shi-long Xiang, Da-jin Chen, Hui-yao Lan, Jiang-hua Chen

Published Jul 13, 2015 · Vol. 6, No. 19 · pp. 17016-17030

Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma Research Paper

Chonglei Bi, Tae-Hoon Chung, Gaofeng Huang, Jianbiao Zhou, Junli J. Yan, Rafael Fonseca, Wee Joo Chng

Published Jul 3, 2015 · Vol. 6, No. 28 · pp. 26508-26518

Multimodal imaging guided preclinical trials of vascular targeting in prostate cancer Research Paper

James Kalmuk, Margaret Folaron, Julian Buchinger, Roberto Pili, Mukund Seshadri

Published Jul 2, 2015 · Vol. 6, No. 27 · pp. 24376-24392

eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer Research Paper

Min-Wu Chao, Li-Ting Wang, Chin-Yu Lai, Xiao-Ming Yang, Ya-Wen Cheng, Kuo-Hsiung Lee, Shiow-Lin Pan, Che-Ming Teng

Published Jun 29, 2015 · Vol. 6, No. 27 · pp. 24092-24104

ErbB-3 activation by NRG-1Î² sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs) Priority Research Paper

Pramudita R. Prasetyanti, Emily Capone, Daniela Barcaroli, Daniela Dâ€™Agostino, Silvia Volpe, Antonina Benfante, Sander van Hooff, Valentina Iacobelli, Cosmo Rossi, Stefano Iacobelli, Jan Paul Medema, Vincenzo De Laurenzi, Gianluca Sala

Published Jun 25, 2015 · Vol. 6, No. 19 · pp. 16902-16911

Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells Research Paper

Xin Liu, Xin Chen, Kiera Rycaj, Hsueh-Ping Chao, Qu Deng, Collene Jeter, Can Liu, Sofia Honorio, Hangwen Li, Tammy Davis, Mahipal Suraneni, Brian Laffin, Jichao Qin, Qiuhui Li, Tao Yang, Pamela Whitney, Jianjun Shen, Jiaoti Huang, Dean G. Tang

Published Jun 24, 2015 · Vol. 6, No. 27 · pp. 23959-23986

Exploring response signals and targets in aggressive unresectable hepatocellular carcinoma: an analysis of targeted therapy phase 1 trials Clinical Research Papers

Ishwaria M. Subbiah, Gerald S. Falchook, Ahmed O. Kaseb, Kenneth R. Hess, Apostolia M. Tsimberidou, Siqing Fu, Vivek Subbiah, David S. Hong, Aung Naing, Sarina A. Piha-Paul, Owais Akmal, Filip Janku, Razelle Kurzrock

Published Jun 23, 2015 · Vol. 6, No. 29 · pp. 28453-28462

Predominant Rab-GTPase amplicons contributing to oral squamous cell carcinoma progression to metastasis Research Paper

Sabrina Daniela da Silva, Fabio Albuquerque Marchi, Bin Xu, Krikor Bijian, Faisal Alobaid, Alex Mlynarek, Silvia Regina Rogatto, Michael Hier, Luiz Paulo Kowalski, Moulay A. Alaoui-Jamali

Published Jun 15, 2015 · Vol. 6, No. 26 · pp. 21950-21963

Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition Research Paper

Hanbing An, Sydney L. Stoops, Natasha G. Deane, Jing Zhu, Jinghuan Zi, Connie Weaver, Alex G. Waterson, Andries Zijlstra, Craig W. Lindsley, Robert Daniel Beauchamp

Published Jun 15, 2015 · Vol. 6, No. 26 · pp. 22934-22948

Targeting cancer cell metabolism in pancreatic adenocarcinoma Review

Romain Cohen, Cindy Neuzillet, AnnemilaÃ¯ Tijeras-Raballand, Sandrine Faivre, Armand de Gramont, Eric Raymond

Published Jun 10, 2015 · Vol. 6, No. 19 · pp. 16832-16847

Digesting dietary miRNA therapeutics Editorial

Mark Yarmarkovich, Kendal D. Hirschi

Published Jun 8, 2015 · Vol. 6, No. 16 · pp. 13848-13849

The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia Research Paper

SÃlvia Xargay-Torrent, MÃ³nica LÃ³pez-Guerra, Laia Rosich, Arnau Montraveta, Jocabed RoldÃ¡n, Vanina RodrÃguez, Neus Villamor, Marta Aymerich, Chandraiah Lagisetti, Thomas R. Webb, Carlos LÃ³pez-OtÃn, Elias Campo, Dolors Colomer

Published Jun 8, 2015 · Vol. 6, No. 26 · pp. 22734-22749

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Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells Research Paper

High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma Research Paper

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy Research Paper

An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy Research Paper

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells Research Paper

Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model Research Paper

Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo Research Paper

Deletion of Smad3 improves cardiac allograft rejection in mice Research Paper

Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma Research Paper

Multimodal imaging guided preclinical trials of vascular targeting in prostate cancer Research Paper

eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer Research Paper

ErbB-3 activation by NRG-1Î² sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs) Priority Research Paper

Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells Research Paper

Exploring response signals and targets in aggressive unresectable hepatocellular carcinoma: an analysis of targeted therapy phase 1 trials Clinical Research Papers

Predominant Rab-GTPase amplicons contributing to oral squamous cell carcinoma progression to metastasis Research Paper

Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition Research Paper

Targeting cancer cell metabolism in pancreatic adenocarcinoma Review

Digesting dietary miRNA therapeutics Editorial

The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells Research Paper

High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma Research Paper

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy Research Paper

An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy Research Paper

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells Research Paper

Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model Research Paper

Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo Research Paper

Deletion of Smad3 improves cardiac allograft rejection in mice Research Paper

Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma Research Paper

Multimodal imaging guided preclinical trials of vascular targeting in prostate cancer Research Paper

eIF4E binding protein 1 expression is associated with clinical survival outcomes in colorectal cancer Research Paper

ErbB-3 activation by NRG-1Î² sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs) Priority Research Paper

Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells Research Paper

Exploring response signals and targets in aggressive unresectable hepatocellular carcinoma: an analysis of targeted therapy phase 1 trials Clinical Research Papers

Predominant Rab-GTPase amplicons contributing to oral squamous cell carcinoma progression to metastasis Research Paper

Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition Research Paper

Targeting cancer cell metabolism in pancreatic adenocarcinoma Review

Digesting dietary miRNA therapeutics Editorial

The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia Research Paper