The Oncosearch | Oncotarget

A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase Research Paper

Nandini Sakurikar, Ruth Thompson, Ryan Montano, Alan Eastman

Published Nov 22, 2015 · Vol. 7, No. 2 · pp. 1380-1394

KIAA0101 is associated with human renal cell carcinoma proliferation and migration induced by erythropoietin Research Paper

Shengjun Fan, Xin Li, Lu Tie, Yan Pan, Xuejun Li

Published Nov 12, 2015 · Vol. 7, No. 12 · pp. 13520-13537

Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) beyond KIT/PDGFRÎ± genotype evaluated by next generation sequencing (NGS) Research Paper

Maristella Saponara, Milena Urbini, Annalisa Astolfi, Valentina Indio, Giorgio Ercolani, Massimo Del Gaudio, Donatella Santini, Maria Giulia Pirini, Michelangelo Fiorentino, Margherita Nannini, Cristian Lolli, Anna Mandrioli, Lidia Gatto, Giovanni Brandi, Guido Biasco, Antonio Daniele Pinna, Maria Abbondanza Pantaleo

Published Nov 2, 2015 · Vol. 6, No. 39 · pp. 42243-42257

Isothiocyanatostilbenes as novel c-Met inhibitors Research Paper

Alana L. Gray, David T. Coleman, Reneau F. Castore, Mohamed M. Mohyeldin, Khalid A. El Sayed, James A. Cardelli

Published Oct 31, 2015 · Vol. 6, No. 38 · pp. 41180-41193

Tumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugs Review

Che-Hsin Lee, Cheng-Chia Yu, Bing-Yen Wang, Wen-Wei Chang

Published Oct 31, 2015 · Vol. 7, No. 2 · pp. 1215-1226

Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma Research Paper

Igor F. Tsigelny, Rajesh Mukthavaram, Valentina L. Kouznetsova, Ying Chao, Ivan Babic, Elmar Nurmemmedov, Sandra Pastorino, Pengfei Jiang, David Calligaris, Nathalie Agar, Miriam Scadeng, Sandeep C. Pingle, Wolfgang Wrasidlo, Milan T. Makale, Santosh Kesari

Published Oct 30, 2015 · Vol. 8, No. 14 · pp. 22370-22384

Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways Research Paper

David W. Greening, Sze Ting Lee, Hong Ji, Richard J. Simpson, Angela Rigopoulos, Carmel Murone, Catherine Fang, Sylvia Gong, Graeme Oâ€™Keefe, Andrew M. Scott

Published Oct 26, 2015 · Vol. 6, No. 35 · pp. 38166-38180

Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer Review

Wei Hu, Chongxi Fan, Peng Jiang, Zhiqiang Ma, Xiaolong Yan, Shouyin Di, Shuai Jiang, Tian Li, Yedong Cheng, Yang Yang

Published Oct 25, 2015 · Vol. 7, No. 1 · pp. 209-223

Tumors with high-density tumor infiltrating lymphocytes constitute a favorable entity in breast cancer: a pooled analysis of four prospective adjuvant trials Clinical Research Papers

Vassiliki Kotoula, Kyriakos Chatzopoulos, Sotiris Lakis, Zoi Alexopoulou, Eleni Timotheadou, Flora Zagouri, George Pentheroudakis, Helen Gogas, Eleni Galani, Ioannis Efstratiou, Thomas Zaramboukas, Angelos Koutras, Gerasimos Aravantinos, Epaminontas Samantas, Amanda Psyrri, Helen Kourea, Mattheos Bobos, Pavlos Papakostas, Paris Kosmidis, Dimitrios Pectasides, George Fountzilas

Published Oct 25, 2015 · Vol. 7, No. 4 · pp. 5074-5087

5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53 Research Paper

Birce Akpinar, Ethiene V. Bracht, Dorin Reijnders, Barbora Safarikova, Iva Jelinkova, Alf Grandien, Alena Hyrslova Vaculova, Boris Zhivotovsky, Magnus Olsson

Published Oct 24, 2015 · Vol. 6, No. 41 · pp. 43679-43697

Novel C6-substituted 1,3,4-oxadiazinones as potential anti-cancer agents Research Paper

Maqusood Md. Alam, Su-Chan Lee, Yujin Jung, Hye Jeong Yun, Hye-Young Min, Ho Jin Lee, Phuong Chi Pham, Jayoung Moon, Dah In Kwon, Bumhee Lim, Young-Ger Suh, Jeeyeon Lee, Ho-Young Lee

Published Oct 23, 2015 · Vol. 6, No. 38 · pp. 40598-40610

Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer Research Paper

Wei-Ching Chen, Yung-Sheng Chang, Hui-Ping Hsu, Meng-Chi Yen, Hau-Lun Huang, Chien-Yu Cho, Chih-Yang Wang, Tzu-Yang Weng, Po-Ting Lai, Ching-Shih Chen, Yih-Jyh Lin, Ming-Derg Lai

Published Oct 22, 2015 · Vol. 6, No. 40 · pp. 42923-42937

Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation Research Paper

Sung-Wook Kim, Ju-Hee Lee, Ji-Hong Moon, Uddin M.D. Nazim, You-Jin Lee, Jae-Won Seol, Jin Hur, Seong-Kug Eo, John-Hwa Lee, Sang-Youel Park

Published Oct 22, 2015 · Vol. 7, No. 4 · pp. 4356-4368

Inhibition of Lyn is a promising treatment for mantle cell lymphoma with bortezomib resistance Research Paper

Areumnuri Kim, Ki Moon Seong, Hye Jin Kang, Sunhoo Park, Seung-Sook Lee

Published Oct 21, 2015 · Vol. 6, No. 35 · pp. 38225-38238

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling Research Paper

Sharon McGonigle, Zhihong Chen, Jiayi Wu, Paul Chang, Donna Kolber-Simonds, Karen Ackermann, Natalie C. Twine, Jue-lon Shie, Jingzang Tao Miu, Kuan-Chun Huang, George A. Moniz, Kenichi Nomoto

Published Oct 20, 2015 · Vol. 6, No. 38 · pp. 41307-41323

Dysregulated expression of cell surface glycoprotein CDCP1 in prostate cancer Research Paper

Lifang Yang, Sucharita M. Dutta, Dean A. Troyer, Jefferson B. Lin, Raymond A. Lance, Julius O. Nyalwidhe, Richard R Drake, O. John Semmes

Published Oct 20, 2015 · Vol. 6, No. 41 · pp. 43743-43758

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro Research Paper

Abdo Mahli, Wolfgang E. Thasler, Eleonora Patsenker, Sebastian MÃ¼ller, Felix Stickel, Martina MÃ¼ller, Helmut K. Seitz, Arthur I. Cederbaum, Claus Hellerbrand

Published Oct 20, 2015 · Vol. 6, No. 39 · pp. 41464-41478

Is lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells? Review

Geoffrey Brown, Isidro Sanchez-Garcia

Published Oct 19, 2015 · Vol. 6, No. 41 · pp. 43326-43341

Bis-cyclopropane analog of disorazole C₁ is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells Research Paper

Shaoyu Wu, Zhijian Guo, Chad D. Hopkins, Ning Wei, Edward Chu, Peter Wipf, John C. Schmitz

Published Oct 19, 2015 · Vol. 6, No. 38 · pp. 40866-40879

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR Research Paper

Sue Ellen Verbrugge, Marjon Al, Yehuda G. Assaraf, Sarah Kammerer, Durga M.S.H. Chandrupatla, Richard Honeywell, Rene P.J. Musters, Elisa Giovannetti, Tom Oâ€™Toole, George L. Scheffer, David Krige, Tanja D. de Gruijl, Hans W.M. Niessen, Willem F. Lems, Pieternella A. Kramer, Rik J. Scheper, Jacqueline Cloos, Gert J. Ossenkoppele, Godefridus J. Peters, Gerrit Jansen

Published Oct 19, 2015 · Vol. 7, No. 5 · pp. 5240-5257

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A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase Research Paper

KIAA0101 is associated with human renal cell carcinoma proliferation and migration induced by erythropoietin Research Paper

Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) beyond KIT/PDGFRÎ± genotype evaluated by next generation sequencing (NGS) Research Paper

Isothiocyanatostilbenes as novel c-Met inhibitors Research Paper

Tumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugs Review

Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma Research Paper

Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways Research Paper

Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer Review

Tumors with high-density tumor infiltrating lymphocytes constitute a favorable entity in breast cancer: a pooled analysis of four prospective adjuvant trials Clinical Research Papers

5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53 Research Paper

Novel C6-substituted 1,3,4-oxadiazinones as potential anti-cancer agents Research Paper

Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer Research Paper

Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation Research Paper

Inhibition of Lyn is a promising treatment for mantle cell lymphoma with bortezomib resistance Research Paper

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling Research Paper

Dysregulated expression of cell surface glycoprotein CDCP1 in prostate cancer Research Paper

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro Research Paper

Is lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells? Review

Bis-cyclopropane analog of disorazole C₁ is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells Research Paper

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase Research Paper

KIAA0101 is associated with human renal cell carcinoma proliferation and migration induced by erythropoietin Research Paper

Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) beyond KIT/PDGFRÎ± genotype evaluated by next generation sequencing (NGS) Research Paper

Isothiocyanatostilbenes as novel c-Met inhibitors Research Paper

Tumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugs Review

Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma Research Paper

Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways Research Paper

Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer Review

Tumors with high-density tumor infiltrating lymphocytes constitute a favorable entity in breast cancer: a pooled analysis of four prospective adjuvant trials Clinical Research Papers

5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53 Research Paper

Novel C6-substituted 1,3,4-oxadiazinones as potential anti-cancer agents Research Paper

Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer Research Paper

Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation Research Paper

Inhibition of Lyn is a promising treatment for mantle cell lymphoma with bortezomib resistance Research Paper

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling Research Paper

Dysregulated expression of cell surface glycoprotein CDCP1 in prostate cancer Research Paper

Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro Research Paper

Is lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells? Review

Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells Research Paper

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR Research Paper

Bis-cyclopropane analog of disorazole C₁ is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells Research Paper