The Oncosearch | Oncotarget

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Abhijit Chakraborty, Faisal Aziz, Eunmiri Roh, Le Thi My Le, Raja Dey, Tianshun Zhang, Moeez G. Rathore, Aalekhya Sharma Biswas, Ann M. Bode, Zigang Dong

Published Apr 17, 2020 · Vol. 11, No. 20 · pp. 1846-1861

Keywords: TIMELESS, TIPIN, apoptosis, xenograft, Cryo-EM

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Wen Luo, Changxin Xu, Sarah Phillips, Aliza Gardenswartz, Jeremy M. Rosenblum, Janet Ayello, Stephen L. Lessnick, Huai-Xiang Hao, Mitchell S. Cairo

Published Apr 16, 2020 · Vol. 11, No. 19 · pp. 1691-1704

Keywords: PPP1R1A, cell cycle control, IGF-1R, metastasis, Ewing sarcoma

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

James R. Browning, Paige Derr, Kristy Derr, Nicole Doudican, Sam Michael, Samantha R. Lish, Nicholas A. Taylor, James G. Krueger, Marc Ferrer, John A. Carucci, Daniel S. Gareau

Published Apr 16, 2020 · Vol. 11, No. 27 · pp. 2587-2596

Keywords: squamous cell carcinoma, screening, 3D printing, in vitro model, confocal microscopy

Lack of CD8⁺ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors Research Paper

Salum J. Lidenge, For Yue Tso, Owen Ngalamika, Jaydeep Kolape, John R. Ngowi, Julius Mwaiselage, Charles Wood, John T. West

Published Apr 16, 2020 · Vol. 11, No. 17 · pp. 1556-1572

Keywords: Kaposi’s sarcoma, HIV-1, KSHV, immune cells, tumor microenvironment

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D’Amico, Antonino Maiorana, Pamela Sighinolfi, Alessandro Stefani, Uliano Morandi, Massimo Dominici, Beatrice Aramini

Published Apr 16, 2020 · Vol. 11, No. 17 · pp. 1545-1555

Keywords: immunophenotype, cancer stem cells, cancer stem-like cells, non-small cell lung cancer (NSCLC), target therapy

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Hisham S. Alhajala, John L. Markley, Jin Hae Kim, Mona M. Al-Gizawiy, Kathleen M. Schmainda, John S. Kuo, Christopher R. Chitambar

Published Apr 15, 2020 · Vol. 11, No. 17 · pp. 1531-1544

Keywords: glioblastoma, iron, gallium, metformin, mitochondrial complex I

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Beatriz Ballester, Javier Milara, Julio Cortijo

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1306-1320

Keywords: pirfenidone, idiopathic pulmonary fibrosis, MUC1, transforming growth factor beta-1, fibroblasts

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Vijay R. Gupta, Adam Root, Timothy Fisher, Rand Norberg, John David, Tracey Clark, Justin Cohen, Chad May, Anand Giddabasappa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1344-1357

Keywords: bispecific antibody, tumor targeting, biodistribution, T cells, molecular imaging

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuwei Liu, Kazuhiro Ooe, Takahiro Teramoto, Atsushi Toyoshima, Eku Shimosegawa, Takashi Nakano, Yoshikatsu Kanai, Atsushi Shinohara, Jun Hatazawa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1388-1398

Keywords: alpha therapy, astatine, glioma, LAT1, phenylalanine

Gene expression dynamic analysis reveals co-activation of Sonic Hedgehog and epidermal growth factor followed by dynamic silencing Research Paper

Vahed Maroufy, Pankil Shah, Arvand Asghari, Nan Deng, Rosemarie N.U. Le, Juan C. Ramirez, Ashraf Yaseen, W. Jim Zheng, Michihisa Umetani, Hulin Wu

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1358-1372

Keywords: pathway cross-talk, gene expression dynamics, gene regulatory network, Sonic Hedgehog, epidermal growth factor

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Marina P. Antoch, Michelle Wrobel, Bryan Gillard, Karen K. Kuropatwinski, Ilia Toshkov, Anatoli S. Gleiberman, Ellen Karasik, Michael T. Moser, Barbara A. Foster, Ekaterina L. Andrianova, Olga V. Chernova, Andrei V. Gudkov

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1373-1387

Keywords: prostate cancer, rapamycin, prevention, mTOR, PTEN

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Indu Kohaar, Qiyuan Li, Yongmei Chen, Lakshmi Ravindranath, Denise Young, Amina Ali, Isabell A. Sesterhenn, Inger L. Rosner, Jennifer Cullen, Shiv Srivastava, Matthew Freedman, Gyorgy Petrovics

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1321-1333

Keywords: prostate cancer, TMPRSS2-ERG, molecular subtype, ERG fusion, SNP

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Cathy Eng, Marwan Fakih, Manik Amin, Van Morris, Howard S. Hochster, Patrick M. Boland, Hope Uronis

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1334-1343

Keywords: anal neoplasms, immunotherapy, Listeria monocytogenes, papillomaviridae, phase II clinical trial

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Gilseung Park, Jessica Burroughs-Garcia, Clay A. Foster, Ameera Hasan, Chiara Borga, J. Kimble Frazer

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1292-1305

Keywords: acute lymphoblastic leukemia, ALL, zebrafish, lymphocyte, MYC

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Vaishali Kapoor, Andrea Collins, Kaylan Griffith, Subhajit Ghosh, Nathan Wong, Xiaowei Wang, Grant A. Challen, Joseph Krambs, Dan Link, Dennis E. Hallahan, Dinesh Thotala

Published Apr 13, 2020 · Vol. 11, No. 19 · pp. 1681-1690

Keywords: radiation, lymphopenia, mass cytometry RNA sequencing

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

Andy Karabajakian, Thibaut Garrivier, Carole Crozes, Nicolas Gadot, Jean-Yves Blay, Frédéric Bérard, Philippe Céruse, Philippe Zrounba, Pierre Saintigny, Charles Mastier, Jérôme Fayette

Published Apr 11, 2020 · Vol. 11, No. 18 · pp. 1618-1628

Keywords: squamous cell carcinoma of head and neck, immunotherapy, programmed cell death 1 receptor, kinetics

Correction: Tacrolimus dose requirement based on the CYP3A5 genotype in renal transplant patients Correction

Lihui Qu, Yingying Lu, Meike Ying, Bingjue Li, Chunhua Weng, Zhoutao Xie, Ludan Liang, Chuan Lin, Xian Yang, Shi Feng, Yucheng Wang, Xiujin Shen, Qin Zhou, Ying Chen, Zhimin Chen, Jianyong Wu, Weiqiang Lin, Yi Shen, Jing Qin, Hang Xu, Feng Xu, Junwen Wang, Jianghua Chen, Hong Jiang, Hongfeng Huang

Published Apr 7, 2020 · Vol. 11, No. 16 · pp. 1474-1477

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

Noora K. Porkka, Alisa Olkinuora, Teijo Kuopio, Maarit Ahtiainen, Samuli Eldfors, Henrikki Almusa, Jukka-Pekka Mecklin, Päivi Peltomäki

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1244-1256

Keywords: Lynch syndrome, breast carcinoma, MSI, DNA mismatch repair, somatic mutation

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

Nagi B. Kumar, Julio Pow-Sang, Philippe Spiess, Shohreh Dickinson, Michael J. Schell

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1218-1234

Keywords: isoflavones, chemoprevention, prostate cancer, African American men, Caucasian men

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Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

Lack of CD8⁺ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Gene expression dynamic analysis reveals co-activation of Sonic Hedgehog and epidermal growth factor followed by dynamic silencing Research Paper

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

Correction: Tacrolimus dose requirement based on the CYP3A5 genotype in renal transplant patients Correction

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

Lack of CD8+ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDHhigh cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1 Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Targeted alpha therapy using astatine (211At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Gene expression dynamic analysis reveals co-activation of Sonic Hedgehog and epidermal growth factor followed by dynamic silencing Research Paper

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

Correction: Tacrolimus dose requirement based on the CYP3A5 genotype in renal transplant patients Correction

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

Lack of CD8⁺ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper