The Oncosearch | Oncotarget

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Katherine M. Bever, Erkut H. Borazanci, Elizabeth A. Thompson, Jennifer N. Durham, Kimberly Pinero, Gayle S. Jameson, Amber Vrana, Meizheng Liu, Cara Wilt, Annie A. Wu, Wei Fu, Hao Wang, Yafu Yin, Jeffrey P. Leal, Ana De Jesus-Acosta, Lei Zheng, Daniel A. Laheru, Daniel D. Von Hoff, Elizabeth M. Jaffee, Jonathan D. Powell, Dung T. Le

Published Apr 23, 2020 · Vol. 11, No. 21 · pp. 1929-1941

Keywords: pancreatic cancer, mTOR inhibition, maintenance therapy, metformin

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

Suparna Mazumder, Valerie Swank, Anton A. Komar, Justin M. Johnson, Vincent K. Tuohy

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1894-1910

Keywords: monoclonal antibody, anti-Müllerian hormone receptor type II, immunotherapy, ovarian cancer, 4D12G1

Clinical implications of chromatin accessibility in human cancers Research Paper

Yuexin Liu

Published Apr 22, 2020 · Vol. 11, No. 18 · pp. 1666-1678

Keywords: ATAC-seq, chromatin accessibility, TCGA, promoter, survival

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1876-1893

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Diana Barea Roldán, Matthias Grimmler, Christoph Hartmann, Stefanie Hubich-Rau, Tim Beißert, Claudia Paret, Giuseppe Cagna, Christoph Rohde, Stefan Wöll, Michael Koslowski, Özlem Türeci, Ugur Sahin

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1862-1875

Keywords: PLAC1, tumorigenesis, extracellular matrix, fibroblast growth factor, AKT

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Masaki Kobayashi, Yuka Ishizaki, Mika Owaki, Yoko Matsumoto, Yuri Kakiyama, Shunsuke Hoshino, Ryoma Tagawa, Yuka Sudo, Naoyuki Okita, Kazunori Akimoto, Yoshikazu Higami

Published Apr 22, 2020 · Vol. 11, No. 18 · pp. 1653-1665

Keywords: nutlin-3a, PARP1, breast cancer, proteasomal degradation, autoPARylation

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Leanne Milton-Harris, Mark Jeeves, Sarah A. Walker, Simon E. Ward, Erika J. Mancini

Published Apr 22, 2020 · Vol. 11, No. 19 · pp. 1737-1748

Keywords: protein-protein interaction, leukaemia, T-ALL, drug discovery, LMO2

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

Lymph nodes may be a source for immunetherapy in gastric cancer Research Paper

Paula Baraúna Assumpção, Erika Couto Canelas, Aline Cruz Ramos, Ana Anaissi, João Felipe Acioli, Geraldo Ishak, Sidney Santos, Samia Demachki, Paulo Assumpção

Published Apr 21, 2020 · Vol. 11, No. 19 · pp. 1729-1736

Keywords: gastric cancer, immunotherapy, lymph nodes

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Mei Zhang, Angela M. Hong

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1417-1426

Keywords: radiosensitivity, oropharyngeal cancer, human papillomavirus, double-strand break, radiobiology

Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Gazanfer Belge, Finja Hennig, Cansu Dumlupinar, Francesca Grobelny, Klaus Junker, Arlo Radtke, Klaus-Peter Dieckmann

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1462-1473

Keywords: testicular germ cell tumors, microRNA-371a-3p, serum, contralateral testes, in situ hybridization

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Thao Pham, Kristin Robinson, Terra Vleeshouwer-Neumann, James E. Annis, Eleanor Y. Chen

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1448-1461

Keywords: rhabdomyosarcoma, self-renewal, GRK5, kinase, cell cycle

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

Al Hassan Kyakulaga, Farrukh Aqil, Radha Munagala, Ramesh C. Gupta

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1399-1416

Keywords: non-small cell lung cancer, withaferin A, synergistic, combination index, paclitaxel

Changes in microRNA expression associated with metastasis and survival in patients with uveal melanoma Research Paper

Ayushi Vashishtha, Tae Jin Lee, Ashok Sharma, John J. Wallbillich

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1435-1447

Keywords: uveal melanoma, metastasis, survival, microRNA, biomarker

Prognostic and predictive factors associated with ipilimumab-related adverse events: a retrospective analysis of 11 NCI-sponsored phase I clinical trials Research Paper

Aman Chauhan, Tanvir Kabir, Jianrong Wu, Jing Wei, Mary Cook, Charles A. Kunos

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1427-1434

Keywords: immunotherapy, toxicity, co-administered agents, metastatic melanoma, immune checkpoint inhibitors

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper

Anindita Tripathy, Sudhir Thakurela, Manoj Kumar Sahu, Kanishka Uthansingh, Ayaskanta Singh, Jimmy Narayan, Amrendra Kumar Ajay, Vinay Singh, Ratna Kumari

Published Apr 20, 2020

Keywords: hepatocellular carcinoma, adiposity, SHH-E2F1 pathway, lipogenic molecules, adiponectin

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Inês Gomes, Bernardo P. de Almeida, Sara Dâmaso, André Mansinho, Inês Correia, Sara Henriques, Raquel Cruz-Duarte, Guilherme Vilhais, Pedro Félix, Patrícia Alves, Patrícia Corredeira, Nuno L. Barbosa-Morais, Luis Costa, Sandra Casimiro

Published Apr 18, 2020 · Vol. 11, No. 19 · pp. 1714-1728

Keywords: RANKL-RANK pathway, ER+ breast cancer, resistance to chemo and hormone therapy, stemness, metastization

Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study Research Paper

Jéssica Reis Santos, Dan Linetzky Waitzberg, Ismael Dale Cotrim Guerreiro da Silva, Tharcisio Citrangulo Tortelli Junior, Luciana Rodrigues Carvalho Barros, Gisele André Baptista Canuto, Andréa Tedesco Faccio, Lydia Fumiko Yamaguchi, Massuo Jorge Kato, Marina Franco Maggi Tavares, Ana Cristina Martinez, Ângela Flavia Logullo, Raquel Suzana M.M. Torrinhas, Graziela Ravacci

Published Apr 18, 2020 · Vol. 11, No. 18 · pp. 1637-1652

Keywords: invasive ductal carcinoma, targeted metabolomics, untargeted metabolomics, tumor metabolism, one-carbon metabolism

Expression of Nrf2 and NF-κB transcription factors in breast cancer and breast fibroadenoma: Insights for a new therapeutic approach Research Paper

Camila Maria Simplicio-Revoredo, Renato de Oliveira Pereira, Mariella de Almeida Melo, Pedro Vitor Lopes-Costa, Paulo de Tarso Moura-Borges, Emerson Brandão Sousa, Fidelis Manes Neto, Viriato Campelo, Ione Maria Ribeiro Soares-Lopes, Maria da Conceição Barros-Oliveira, Cleciton Braga Tavares, Alesse Ribeiro dos Santos, Camila Guedes Borges de Araújo, Eid Gonçalves Coelho, Larysse Cardoso Campos-Verdes, Aldenora Oliveira do Nascimento-Holanda, Jackeline Lopes Viana, Maria Liduina Meneses Bezerra-Chaves, Rodrigo José de Vasconcelos-Valença, Lina Gomes dos Santos, Lauro Rodolpho Soares-Lopes, André Luiz Pinho-Sobral, Luiz Henrique Gebrim, Benedito Borges da Silva

Published Apr 18, 2020 · Vol. 11, No. 18 · pp. 1629-1636

Keywords: breast cancer, fibroadenoma, NRF2, NF-κB, immunohistochemistry

Relationships of handgrip strength with the presence of cerebral microbleeds and platelet count in older Japanese adults Research Paper

Hirotomo Yamanashi, Kenji Nagaoki, Sinsuke Kanbara, Yuji Shimizu, Kunihiko Murase, Akira Tsujino, Takahiro Maeda

Published Apr 17, 2020 · Vol. 11, No. 19 · pp. 1705-1713

Keywords: sarcopenia, frailty, handgrip strength, cerebral microbleeds, platelet

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An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

Clinical implications of chromatin accessibility in human cancers Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Lymph nodes may be a source for immunetherapy in gastric cancer Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

Changes in microRNA expression associated with metastasis and survival in patients with uveal melanoma Research Paper

Prognostic and predictive factors associated with ipilimumab-related adverse events: a retrospective analysis of 11 NCI-sponsored phase I clinical trials Research Paper

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study Research Paper

Expression of Nrf2 and NF-κB transcription factors in breast cancer and breast fibroadenoma: Insights for a new therapeutic approach Research Paper

Relationships of handgrip strength with the presence of cerebral microbleeds and platelet count in older Japanese adults Research Paper

Publication Alerts

European Cancer and Oncology Congress

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Post-Publication Promotion

Search Oncotarget

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

Clinical implications of chromatin accessibility in human cancers Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Lymph nodes may be a source for immunetherapy in gastric cancer Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

Changes in microRNA expression associated with metastasis and survival in patients with uveal melanoma Research Paper

Prognostic and predictive factors associated with ipilimumab-related adverse events: a retrospective analysis of 11 NCI-sponsored phase I clinical trials Research Paper

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study Research Paper

Expression of Nrf2 and NF-κB transcription factors in breast cancer and breast fibroadenoma: Insights for a new therapeutic approach Research Paper

Relationships of handgrip strength with the presence of cerebral microbleeds and platelet count in older Japanese adults Research Paper