The Oncosearch | Oncotarget

Delivering a RAS protease halts tumor growth Editorial

Vania Vidimar, Roman A. Melnyk, Karla J.F. Satchell

Published Aug 13, 2020 · Vol. 11, No. 35 · pp. 3265-3266

Keywords: RAS, RRSP, chimeric toxins, cancer, xenografts

Diversifying the platinum-based chemotherapy toolkit for immunogenic cancer cell death Editorial

Abhishek D. Garg, Patrizia Agostinis

Published Aug 13, 2020 · Vol. 11, No. 36 · pp. 3352-3353

Keywords: PT-112, immunogenic cell death (ICD), immune-checkpoint blockers (ICBs), tumour microenvironment, apoptosis

Down syndrome iPSC model: endothelial perspective on tumor development Research Paper

Mariana Perepitchka, Yekaterina Galat, Igor P. Beletsky, Philip M. Iannaccone, Vasiliy Galat

Published Aug 12, 2020 · Vol. 11, No. 36 · pp. 3387-3404

Keywords: Down syndrome, iPSC-derived endothelial model, T21 genome-wide Implications, meta-analysis, tumor microenvironment

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements Research Paper

Adélia Mendes, Ramona Jühlen, Valérie Martinelli, Birthe Fahrenkrog

Published Aug 11, 2020 · Vol. 11, No. 36 · pp. 3371-3386

Keywords: CRM1, NUP214, leukemia, nuclear export, nucleoporin

Therapeutic applications of the selective high affinity ligand drug SH7139 extend beyond non-Hodgkin’s lymphoma to many other types of solid cancers Research Paper

Rod Balhorn, Monique Cosman Balhorn

Published Aug 5, 2020 · Vol. 11, No. 35 · pp. 3315-3349

Keywords: HLA-DR, selective high affinity ligand, SH7139, SH7129, solid cancers

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

Angel Núñez-Marrero, Nelly Arroyo, Lenin Godoy, Mohammad Zillur Rahman, Jaime L. Matta, Julie Dutil

Published Aug 5, 2020 · Vol. 11, No. 37 · pp. 3420-3431

Keywords: breast cancer, interleukin-12 (IL-12), IL-12 signaling, genetic association, single nucleotide polymorphisms

The temporal effects of topical NF-κB inhibition, in the in vivo prevention of bile-related oncogenic mRNA and miRNA phenotypes in murine hypopharyngeal mucosa: a preclinical model Research Paper

Dimitra P. Vageli, David Kasle, Sotirios G. Doukas, Panagiotis G. Doukas, Clarence T. Sasaki

Published Aug 3, 2020 · Vol. 11, No. 35 · pp. 3303-3314

Keywords: NF-κB inhibition, BAY 11-7082, bile, laryngopharyngeal reflux, hypopharyngeal cancer

Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways Research Paper

Haiming Liu, Jiaohua Luo, Bobby Guillory, Ji-an Chen, Pu Zang, Jordan K. Yoeli, Yamileth Hernandez, Ian (In-gi) Lee, Barbara Anderson, Mackenzie Storie, Alison Tewnion, Jose M. Garcia

Published Aug 3, 2020 · Vol. 11, No. 35 · pp. 3286-3302

Keywords: cachexia, cancer, muscle, ghrelin, adipose tissue

Sequencing for an interdisciplinary molecular tumor board in patients with advanced breast cancer: experiences from a case series Research Paper

Christina Walter, Andreas Hartkopf, Andre Koch, Marion Klaumünzer, Martin Schulze, Eva-Maria Grischke, Florin-Andrei Taran, Sara Brucker, Florian Battke, Saskia Biskup

Published Aug 1, 2020 · Vol. 11, No. 35 · pp. 3279-3285

Keywords: breast cancer, genetics, next-generation sequencing, actionable mutations

GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma and APOBEC3B is directly transcriptionally regulated by GATA3 Research Paper

Sudheer Kumar Gara, Monica Varun Tyagi, Dhaval Thakkur Patel, Kelli Gaskins, Justin Lack, Yi Liu, Electron Kebebew

Published Jul 30, 2020 · Vol. 11, No. 36 · pp. 3354-3370

Keywords: adrenocortical carcinoma, APOBEC3B, GATA3, prognosis, DNA damage

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Matthew J. Kling, Nagendra K. Chaturvedi, Varun Kesherwani, Don W. Coulter, Timothy R. McGuire, J. Graham Sharp, Shantaram S. Joshi

Published Jul 30, 2020 · Vol. 11, No. 40 · pp. 3633-3645

Keywords: exosomes, hypoxia, Ewing’s sarcoma, stemness, miR-210

A case report of metastatic giant sarcomatoid melanoma with BRAF V600E mutation: a complete response to targeted therapy Case Report

Matteo Torresetti, Donatella Brancorsini, Francesca Morgese, Valeria Cognigni, Alessandro Scalise, Rossana Berardi, Giovanni Di Benedetto

Published Jul 30, 2020 · Vol. 11, No. 34 · pp. 3256-3262

Keywords: sarcomatoid melanoma, giant melanoma, BRAF mutation, targeted therapy, next-generation sequencing

Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer Research Paper

Thomas R. Holmes, Jenan Al-Matouq, Matti Holmes, Lauren Nicola, Justin C. Rudd, Sándor Lovas, Laura A. Hansen

Published Jul 30, 2020 · Vol. 11, No. 35 · pp. 3267-3278

Keywords: skin cancer, squamous cell carcinoma, CDC25A, 14-3-3ε, apoptosis

The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling Research Paper

Annamil Alvarez-Trotta, Zhiqiang Wang, Elena Shersher, Bin Li, Jun Long, Ines Lohse, Claes Wahlestedt, Wael El-Rifai, David J. Robbins, Anthony J. Capobianco

Published Jul 28, 2020 · Vol. 11, No. 33 · pp. 3174-3187

Keywords: IBET-151, esophageal adenocarcinoma, GDC-0449 resistance, patient-derived xenografts, Hedgehog/GLI signaling pathway

An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course Research Paper

Guilherme Rossi Assis-Mendonça, André Fattori, Rafael Malagoli Rocha, Gustavo Jacob Lourenço, Márcia Torresan Delamain, Suely Nonogaki, Vladmir Cláudio Cordeiro de Lima, Gisele Wally Braga Colleoni, Cármino Antonio de Souza, Fernando Augusto Soares, Carmen Silvia Passos Lima, José Vassallo

Published Jul 25, 2020 · Vol. 11, No. 33 · pp. 3153-3173

Keywords: follicular lymphoma, tumor microenvironment, immunohistochemistry, single nucleotide polymorphisms, prognosis

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Rachael A. Clark, Sora Lee, Jingbo Qiao, Dai H. Chung

Published Jul 23, 2020 · Vol. 11, No. 32 · pp. 3069-3077

Keywords: neuroblastoma, pralatrexate, N-myc, folate metabolism

Urinary glycoproteomic profiling of non-muscle invasive and muscle invasive bladder carcinoma patients reveals distinct N-glycosylation pattern of CD44, MGAM, and GINM1 Research Paper

Gajanan Sathe, Irene A. George, Barnali Deb, Ankit P. Jain, Krishna Patel, Brusabhanu Nayak, Subhradip Karmakar, Amlesh Seth, Akhilesh Pandey, Prashant Kumar

Published Jul 23, 2020 · Vol. 11, No. 34 · pp. 3244-3255

Keywords: urothelial carcinoma, N-linked glycoproteomics, urine proteomics, NMIBC, MIBC

Post FDA approval analysis of 200 gallium-68 DOTATATE imaging: A retrospective analysis in neuroendocrine tumor patients Research Paper

Aman Chauhan, Riham El-Khouli, Timothy Waits, Rohitashva Agrawal, Fariha Siddiqui, Zachary Tarter, Millicent Horn, Heidi Weiss, Elizabeth Oates, B. Mark Evers, Lowell Anthony

Published Jul 22, 2020 · Vol. 11, No. 32 · pp. 3061-3068

Keywords: gallium-68 DOTATATE, neuroendocrine diagnosis, NET

Losartan improves the therapeutic effect of metronomic cyclophosphamide in triple negative mammary cancer models Research Paper

Leandro E. Mainetti, María José Rico, Cintia Daniela Kaufman, Monica Carolina Grillo, Julian Guercetti, María Virginia Baglioni, Antonela Del Giúdice, Maria Celeste Capitani, Matias Fusini, Viviana Rosa Rozados, O. Graciela Scharovsky

Published Jul 22, 2020 · Vol. 11, No. 32 · pp. 3048-3060

Keywords: mammary cancer, metronomic chemotherapy, drug repurposing, cyclophosphamide, losartan

Differentially expressed full-length, fusion and novel isoforms transcripts-based signature of well-differentiated keratinized oral squamous cell carcinoma Research Paper

Neetu Singh, Dinesh Kumar Sahu, Ratnesh Kumar Tripathi, Archana Mishra, Hari Shyam, Pratap Shankar, Mayank Jain, Nawazish Alam, Anil Kumar, Abhishek Mishra, Rebecca Chowdhry, Anjana Singh, Sameer Gupta, Divya Mehrotra, Preeti Agarwal, Madhu Mati Goel, Arun Chaturvedi, Satya Prakash Agarwal, Manish Bajpai, Devendra Kumar Gupta, Madan Lal Brahma Bhatt, Ravi Kant

Published Jul 22, 2020 · Vol. 11, No. 34 · pp. 3227-3243

Keywords: oral tongue squamous cell carcinoma, microarray, transcriptomics, integrative bioinformatics, differentially expressed gene

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Delivering a RAS protease halts tumor growth Editorial

Diversifying the platinum-based chemotherapy toolkit for immunogenic cancer cell death Editorial

Down syndrome iPSC model: endothelial perspective on tumor development Research Paper

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements Research Paper

Therapeutic applications of the selective high affinity ligand drug SH7139 extend beyond non-Hodgkin’s lymphoma to many other types of solid cancers Research Paper

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

The temporal effects of topical NF-κB inhibition, in the in vivo prevention of bile-related oncogenic mRNA and miRNA phenotypes in murine hypopharyngeal mucosa: a preclinical model Research Paper

Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways Research Paper

Sequencing for an interdisciplinary molecular tumor board in patients with advanced breast cancer: experiences from a case series Research Paper

GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma and APOBEC3B is directly transcriptionally regulated by GATA3 Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

A case report of metastatic giant sarcomatoid melanoma with BRAF V600E mutation: a complete response to targeted therapy Case Report

Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer Research Paper

The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling Research Paper

An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course Research Paper

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Urinary glycoproteomic profiling of non-muscle invasive and muscle invasive bladder carcinoma patients reveals distinct N-glycosylation pattern of CD44, MGAM, and GINM1 Research Paper

Post FDA approval analysis of 200 gallium-68 DOTATATE imaging: A retrospective analysis in neuroendocrine tumor patients Research Paper

Losartan improves the therapeutic effect of metronomic cyclophosphamide in triple negative mammary cancer models Research Paper

Differentially expressed full-length, fusion and novel isoforms transcripts-based signature of well-differentiated keratinized oral squamous cell carcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Delivering a RAS protease halts tumor growth Editorial

Diversifying the platinum-based chemotherapy toolkit for immunogenic cancer cell death Editorial

Down syndrome iPSC model: endothelial perspective on tumor development Research Paper

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements Research Paper

Therapeutic applications of the selective high affinity ligand drug SH7139 extend beyond non-Hodgkin’s lymphoma to many other types of solid cancers Research Paper

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

The temporal effects of topical NF-κB inhibition, in the in vivo prevention of bile-related oncogenic mRNA and miRNA phenotypes in murine hypopharyngeal mucosa: a preclinical model Research Paper

Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways Research Paper

Sequencing for an interdisciplinary molecular tumor board in patients with advanced breast cancer: experiences from a case series Research Paper

GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma and APOBEC3B is directly transcriptionally regulated by GATA3 Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

A case report of metastatic giant sarcomatoid melanoma with BRAF V600E mutation: a complete response to targeted therapy Case Report

Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer Research Paper

The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling Research Paper

An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course Research Paper

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Urinary glycoproteomic profiling of non-muscle invasive and muscle invasive bladder carcinoma patients reveals distinct N-glycosylation pattern of CD44, MGAM, and GINM1 Research Paper

Post FDA approval analysis of 200 gallium-68 DOTATATE imaging: A retrospective analysis in neuroendocrine tumor patients Research Paper

Losartan improves the therapeutic effect of metronomic cyclophosphamide in triple negative mammary cancer models Research Paper

Differentially expressed full-length, fusion and novel isoforms transcripts-based signature of well-differentiated keratinized oral squamous cell carcinoma Research Paper