The Oncosearch | Oncotarget

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Sandeep S. Negi, Patrick Brown

Published Oct 12, 2015 · Vol. 6, No. 33 · pp. 34846-34858

Novel RNA variants in colorectal cancers Research Paper

Andreas M. Hoff, Bjarne Johannessen, Sharmini Alagaratnam, Sen Zhao, Torfinn Nome, Marthe LÃ¸vf, Anne C. Bakken, Merete Hektoen, Anita Sveen, Ragnhild A. Lothe, Rolf I. Skotheim

Published Oct 12, 2015 · Vol. 6, No. 34 · pp. 36587-36602

Aberrant high expression of immunoglobulin G in epithelial stem/progenitor-like cells contributes to tumor initiation and metastasis Research Paper

Qinyuan Liao, Wei Liu, Yang Liu, Fulin Wang, Chong Wang, Jingxuan Zhang, Ming Chu, Dongyang Jiang, Lin Xiao, Wenwei Shao, Zhengzuo Sheng, Xia Tao, Lei Huo, C. Cameron Yin, Youhui Zhang, Gregory Lee, Jing Huang, Zihai Li, Xiaoyan. Qiu

Published Oct 12, 2015 · Vol. 6, No. 37 · pp. 40081-40094

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas Research Perspective

BegoÃ±a Martin-Castillo, Eugeni Lopez-Bonet, Elisabet CuyÃ s, Gemma ViÃ±as, Sonia Pernas, Joan Dorca, Javier A. Menendez

Published Oct 12, 2015 · Vol. 6, No. 32 · pp. 32317-32338

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma Research Paper

Hans Prenen, Dominiek Smeets, Massimiliano Mazzone, Diether Lambrechts, Xavier Sagaert, Raf Sciot, Maria Debiec-Rychter

Published Oct 10, 2015 · Vol. 6, No. 34 · pp. 36418-36425

Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells Research Paper

Simona Camorani, Elvira Crescenzi, David Colecchia, Andrea Carpentieri, Angela Amoresano, Monica Fedele, Mario Chiariello, Laura Cerchia

Published Oct 10, 2015 · Vol. 6, No. 35 · pp. 37570-37587

Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer Research Paper

Baofang Yang, Minxia Zhang, Jian Gao, Jiahuang Li, Lu Fan, Gang Xiang, Xingqi Wang, Xiaoning Wang, Xuefeng Wu, Yang Sun, Xudong Wu, Guang Liang, Yan Shen, Qiang Xu

Published Oct 10, 2015 · Vol. 6, No. 35 · pp. 37613-37625

Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3â€²-shore Research Paper

Jong-Lyul Park, Hee-Jin Kim, Eun-Hye Seo, Oh-Hyung Kwon, Byungho Lim, Mirang Kim, Seon-Young Kim, Kyu-Sang Song, Gyeong Hoon Kang, Hyun Ja Kim, Bo Youl Choi, Yong Sung Kim

Published Oct 10, 2015 · Vol. 6, No. 35 · pp. 37647-37662

Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1 Research Paper

Zongwei Gao, Qingjuan Shang, Zhaoyun Liu, Chun Deng, Chunbao Guo

Published Oct 9, 2015 · Vol. 6, No. 34 · pp. 36338-36353

Inhibiting bladder tumor growth with a cell penetrating R11 peptide derived from the p53 C-terminus Research Paper

Tingting Zhang, Kaijie Wu, Chen Ding, Kangwei Sun, Zhenfeng Guan, Xinyang Wang, Jer-Tsong Hsieh, Dalin He, Jinhai Fan

Published Oct 8, 2015 · Vol. 6, No. 35 · pp. 37782-37791

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients Research Paper

Leticia De Mattos-Arruda, Giulia Bottai, Paolo G. Nuciforo, Luca Di Tommaso, Elisa Giovannetti, Vicente Peg, Agnese Losurdo, JosÃ© PÃ©rez-Garcia, Giovanna Masci, Fabio Corsi, Javier CortÃ©s, Joan Seoane, George A. Calin, Libero Santarpia

Published Oct 7, 2015 · Vol. 6, No. 35 · pp. 37269-37280

Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo Research Paper

Annarita Miluzio, Stefania Oliveto, Elisa Pesce, Luciano Mutti, Bruno Murer, Stefano Grosso, Sara Ricciardi, Daniela Brina, Stefano Biffo

Published Oct 6, 2015 · Vol. 6, No. 35 · pp. 37471-37485

Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients Clinical Research Papers

Seung Tae Kim, Won Suk Lee, Richard B. Lanman, Stefanie Mortimer, Oliver A. Zill, Kyoung-Mee Kim, Kee Taek Jang, Seok-Hyung Kim, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Helmy Eltoukhy, Won Ki Kang, Woo Yong Lee, Hee-Cheol Kim, Keunchil Park, Jeeyun Lee, AmirAli Talasaz

Published Oct 5, 2015 · Vol. 6, No. 37 · pp. 40360-40369

Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses Review

Alberto Ocana, Josee-Lyne Ethier, Laura DÃez-GonzÃ¡lez, VerÃ³nica Corrales-SÃ¡nchez, Amirrtha Srikanthan, MarÃa J. GascÃ³n-Escribano, Arnoud J. Templeton, Francisco Vera-Badillo, Bostjan Seruga, Saroj Niraula, Atanasio Pandiella, Eitan Amir

Published Oct 4, 2015 · Vol. 6, No. 37 · pp. 39538-39549

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Valentina Restelli, Rosaria ChilÃ, Monica Lupi, Andrea Rinaldi, Ivo Kwee, Francesco Bertoni, Giovanna Damia, Laura Carrassa

Published Oct 2, 2015 · Vol. 6, No. 35 · pp. 37229-37240

Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9 Research Paper

Published Oct 2, 2015 · Vol. 6, No. 31 · pp. 31740-31757

Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas Research Paper

Yari Ciribilli, Prashant Singh, Reinhard Spanel, Alberto Inga, JÃ¼rgen Borlak

Published Oct 2, 2015 · Vol. 6, No. 31 · pp. 31569-31592

PRIMA-1^met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms Research Paper

Xiao-Lan Li, Jianbiao Zhou, Zit-Liang Chan, Jing-Yuan Chooi, Zhi-Rong Chen, Wee-Joo Chng

Published Oct 1, 2015 · Vol. 6, No. 34 · pp. 36689-36699

microRNA-7 as a tumor suppressor and novel therapeutic for adrenocortical carcinoma Research Paper

Anthony R Glover, Jing Ting Zhao, Anthony J Gill, Jocelyn Weiss, Nancy Mugridge, Edward Kim, Alex L Feeney, Julian C Ip, Glen Reid, Stephen Clarke, Patsy S H Soon, Bruce G Robinson, Himanshu Brahmbhatt, Jennifer A. MacDiarmid, Stan B Sidhu

Published Oct 1, 2015 · Vol. 6, No. 34 · pp. 36675-36688

Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice Research Paper

LuÃs Felipe Campesato, Romualdo Barroso-Sousa, Leandro Jimenez, Bruna R. Correa, Jorge Sabbaga, Paulo M. Hoff, Luiz F. L. Reis, Pedro Alexandre F. Galante, Anamaria A. Camargo

Published Oct 1, 2015 · Vol. 6, No. 33 · pp. 34221-34227

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Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Novel RNA variants in colorectal cancers Research Paper

Aberrant high expression of immunoglobulin G in epithelial stem/progenitor-like cells contributes to tumor initiation and metastasis Research Paper

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas Research Perspective

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma Research Paper

Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells Research Paper

Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer Research Paper

Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3â€²-shore Research Paper

Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1 Research Paper

Inhibiting bladder tumor growth with a cell penetrating R11 peptide derived from the p53 C-terminus Research Paper

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients Research Paper

Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo Research Paper

Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients Clinical Research Papers

Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses Review

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9 Research Paper

Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas Research Paper

PRIMA-1^met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms Research Paper

microRNA-7 as a tumor suppressor and novel therapeutic for adrenocortical carcinoma Research Paper

Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Novel RNA variants in colorectal cancers Research Paper

Aberrant high expression of immunoglobulin G in epithelial stem/progenitor-like cells contributes to tumor initiation and metastasis Research Paper

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas Research Perspective

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma Research Paper

Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells Research Paper

Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer Research Paper

Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3â€²-shore Research Paper

Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1 Research Paper

Inhibiting bladder tumor growth with a cell penetrating R11 peptide derived from the p53 C-terminus Research Paper

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients Research Paper

Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo Research Paper

Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients Clinical Research Papers

Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses Review

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9 Research Paper

Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas Research Paper

PRIMA-1met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms Research Paper

microRNA-7 as a tumor suppressor and novel therapeutic for adrenocortical carcinoma Research Paper

Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice Research Paper

PRIMA-1^met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms Research Paper