The Oncosearch | Oncotarget

Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes Research Paper

Lisa Ott de Bruin, Wei Yang, Kelly Capuder, Yu Nee Lee, Maddalena Antolini, Robin Meyers, Martin Gellert, Kiran Musunuru, John Manis, Luigi Notarangelo

Published Feb 12, 2016 · Vol. 7, No. 11 · pp. 12962-12974

Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy Research Paper

Helen Creedon, Laura GÃ³mez-Cuadrado, Å½ygimantÄ— TarnauskaitÄ—, Jozef Balla, Marta Canel, Kenneth G. MacLeod, Bryan Serrels, Craig Fraser, Asier Unciti-Broceta, Natasha Tracey, Thierry Le Bihan, Teresa Klinowska, Andrew H. Sims, Adam Byron, Valerie G. Brunton

Published Feb 11, 2016 · Vol. 7, No. 10 · pp. 11539-11552

A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells Research Paper

Chongqiang Zhao, Wenlong Wang, Wenying Yu, David Jou, Yina Wang, Haiyan Ma, Hui Xiao, Hua Qin, Cuntai Zhang, Jiagao LÃ¼, Sheng Li, Chenglong Li, Jiayuh Lin, Li Lin

Published Feb 11, 2016 · Vol. 7, No. 11 · pp. 12917-12926

Comparison of the RECIST 1.0 and RECIST 1.1 in patients treated with targeted agents: a pooled analysis and review Research Paper

Jung Han Kim

Published Feb 11, 2016 · Vol. 7, No. 12 · pp. 13680-13687

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation Research Paper

Nayoung Kim, Ahye Cho, Hideo Watanabe, Yoon-La Choi, Meraj Aziz, Michelle Kassner, Je-Gun Joung, Angela Kyung-Joo Park, Joshua M. Francis, Joon Seol Bae, Soo-min Ahn, Kyoung-Mee Kim, Joon Oh Park, Woong-Yang Park, Myung-Ju Ahn, Keunchil Park, Jaehyung Koo, Hongwei Holly Yin, Jeonghee Cho

Published Feb 11, 2016 · Vol. 7, No. 12 · pp. 13797-13809

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSAâˆ’/lo castration-resistant cells Research Paper

Kiera Rycaj, Eun Jeong Cho, Xin Liu, Hsueh-Ping Chao, Bigang Liu, Qiuhui Li, Ashwini K. Devkota, Dingxiao Zhang, Xin Chen, John Moore, Kevin N. Dalby, Dean G. Tang

Published Feb 10, 2016 · Vol. 7, No. 12 · pp. 14220-14240

Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-ÎºB pathway Research Paper

Si Han Sherman Ho, Azhar Ali, Tan Min Chin, Mei Lin Go

Published Feb 10, 2016 · Vol. 7, No. 10 · pp. 11625-11636

Inverse agonist of estrogen-related receptor Î± suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways Research Paper

Ying-Min Wu, Zhuo-Jia Chen, Guan-Min Jiang, Kun-Shui Zhang, Qiao Liu, Shu-Wei Liang, Yan Zhou, Hong-Bin Huang, Jun Du, Hong-Sheng Wang

Published Feb 9, 2016 · Vol. 7, No. 11 · pp. 12568-12581

Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state Priority Research Paper

Joseph X. Zhou, Zerrin Isik, Caide Xiao, Irit Rubin, Stuart A. Kauffman, Michael Schroeder, Sui Huang

Published Feb 9, 2016 · Vol. 7, No. 7 · pp. 7415-7425

Therapeutic response and side effects of repeated radioligand therapy with ¹⁷⁷Lu-PSMA-DKFZ-617 of castrate-resistant metastatic prostate cancer Research Paper

Hojjat Ahmadzadehfar, Elisabeth Eppard, Stefan KÃ¼rpig, Rolf Fimmers, Anna Yordanova, Carl Diedrich Schlenkhoff, Florian GÃ¤rtner, Sebastian Rogenhofer, Markus Essler

Published Feb 8, 2016 · Vol. 7, No. 11 · pp. 12477-12488

Beyond evidence-based data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma Review

Lorena Incorvaia, Giuseppe Bronte, Viviana Bazan, Giuseppe Badalamenti, Sergio Rizzo, Gianni Pantuso, Clara Natoli, Antonio Russo

Published Feb 8, 2016 · Vol. 7, No. 16 · pp. 21259-21271

Diallyl disulfide suppresses epithelial-mesenchymal transition, invasion and proliferation by downregulation of LIMK1 in gastric cancer Research Paper

Bo Su, Jian Su, Ying Zeng, Fang Liu, Hong Xia, Yan-hua Ma, Zhi-gang Zhou, Shuo Zhang, Bang-min Yang, You-Hua Wu, Xi Zeng, Xiao- Hong Ai, Hui Ling, Hao Jiang, Qi Su

Published Feb 8, 2016 · Vol. 7, No. 9 · pp. 10498-10512

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition Research Paper

Srikumar M. Raja, Swapnil S. Desale, Bhopal Mohapatra, Haitao Luan, Kruti Soni, Jinjin Zhang, Matthew A. Storck, Dan Feng, Timothy A. Bielecki, Vimla Band, Samuel M. Cohen, Tatiana K. Bronich, Hamid Band

Published Feb 7, 2016 · Vol. 7, No. 9 · pp. 10522-10535

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus Research Paper

Sun Min Lim, Hyung Soon Park, Sangwoo Kim, Sora Kim, Siraj M. Ali, Joel R. Greenbowe, In Seok Yang, Nak-Jung Kwon, Jae Lyun Lee, Min-Hee Ryu, Jin-Hee Ahn, Jeeyun Lee, Min Goo Lee, Hyo Song Kim, Hyunki Kim, Hye Ryun Kim, Yong Wha Moon, Hyun Cheol Chung, Joo-Hang Kim, Yoon-Koo Kang, Byoung Chul Cho

Published Feb 7, 2016 · Vol. 7, No. 9 · pp. 10547-10556

Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity Research Paper

Li Yuan, Hong-Mei Yi, Hong Yi, Jia-Quan Qu, Jin-Feng Zhu, Li-Na Li, Ta Xiao, Zhen Zheng, Shan-Shan Lu, Zhi-Qiang Xiao

Published Feb 5, 2016 · Vol. 7, No. 10 · pp. 11463-11477

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Eva A. Ebbing, Jan Paul Medema, Helene Damhofer, Sybren L. Meijer, Kausilia K. Krishnadath, Mark I. van Berge Henegouwen, Maarten F. Bijlsma, Hanneke W. M. van Laarhoven

Published Feb 5, 2016 · Vol. 7, No. 9 · pp. 10243-10254

Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide Research Paper

Charles C. Cates, Angelo D. Arias, Lynn S. Nakayama Wong, Michael W. LamÃ©, Maxim Sidorov, Geraldine Cayanan, Douglas J. Rowland, Jennifer Fung, Georg Karpel-Massler, Markus D. Siegelin, Lloyd A. Greene, James M. Angelastro

Published Feb 5, 2016 · Vol. 7, No. 11 · pp. 12718-12730

Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation Research Paper

Yue Jin, Qingsong Cai, Anitha K. Shenoy, Sangbin Lim, Ying Zhang, Steve Charles, Miriam Tarrash, Xueqi Fu, Sushama Kamarajugadda, Jose G. Trevino, Ming Tan, Jianrong Lu

Published Feb 3, 2016 · Vol. 7, No. 18 · pp. 25113-25124

Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways Research Paper

Li-Jyun Syu, Xinyi Zhao, Yaqing Zhang, Marina Grachtchouk, Elise Demitrack, Alexandre Ermilov, Dawn M. Wilbert, Xinlei Zheng, Ashley Kaatz, Joel K. Greenson, Deborah L. Gumucio, Juanita L. Merchant, Marina Pasca di Magliano, Linda C. Samuelson, Andrzej A. Dlugosz

Published Feb 3, 2016 · Vol. 7, No. 9 · pp. 10255-10270

Stereotactic radiosurgery (SRS) in the modern management of patients with brain metastases Review

Hany Soliman, Sunit Das, David A. Larson, Arjun Sahgal

Published Feb 2, 2016 · Vol. 7, No. 11 · pp. 12318-12330

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Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes Research Paper

Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy Research Paper

A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells Research Paper

Comparison of the RECIST 1.0 and RECIST 1.1 in patients treated with targeted agents: a pooled analysis and review Research Paper

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation Research Paper

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSAâˆ’/lo castration-resistant cells Research Paper

Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-ÎºB pathway Research Paper

Inverse agonist of estrogen-related receptor Î± suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways Research Paper

Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state Priority Research Paper

Therapeutic response and side effects of repeated radioligand therapy with ¹⁷⁷Lu-PSMA-DKFZ-617 of castrate-resistant metastatic prostate cancer Research Paper

Beyond evidence-based data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma Review

Diallyl disulfide suppresses epithelial-mesenchymal transition, invasion and proliferation by downregulation of LIMK1 in gastric cancer Research Paper

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition Research Paper

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus Research Paper

Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity Research Paper

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide Research Paper

Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation Research Paper

Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways Research Paper

Stereotactic radiosurgery (SRS) in the modern management of patients with brain metastases Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes Research Paper

Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy Research Paper

A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells Research Paper

Comparison of the RECIST 1.0 and RECIST 1.1 in patients treated with targeted agents: a pooled analysis and review Research Paper

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation Research Paper

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSAâˆ’/lo castration-resistant cells Research Paper

Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-ÎºB pathway Research Paper

Inverse agonist of estrogen-related receptor Î± suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways Research Paper

Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state Priority Research Paper

Therapeutic response and side effects of repeated radioligand therapy with 177Lu-PSMA-DKFZ-617 of castrate-resistant metastatic prostate cancer Research Paper

Beyond evidence-based data: scientific rationale and tumor behavior to drive sequential and personalized therapeutic strategies for the treatment of metastatic renal cell carcinoma Review

Diallyl disulfide suppresses epithelial-mesenchymal transition, invasion and proliferation by downregulation of LIMK1 in gastric cancer Research Paper

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition Research Paper

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus Research Paper

Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity Research Paper

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3 Research Paper

Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide Research Paper

Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation Research Paper

Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways Research Paper

Stereotactic radiosurgery (SRS) in the modern management of patients with brain metastases Review

Therapeutic response and side effects of repeated radioligand therapy with ¹⁷⁷Lu-PSMA-DKFZ-617 of castrate-resistant metastatic prostate cancer Research Paper