The Oncosearch | Oncotarget

Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma Research Paper

Clemens Krepler, Min Xiao, Minu Samanta, Adina Vultur, Hsin-Yi Chen, Patricia Brafford, Patricia I. Reyes-Uribe, Molly Halloran, Thomas Chen, Xu He, Denitsa Hristova, Qin Liu, Ahmed A. Samatar, Michael A. Davies, Katherine L. Nathanson, Mizuho Fukunaga-Kalabis, Meenhard Herlyn, Jessie Villanueva

Published Sep 16, 2016 · Vol. 7, No. 44 · pp. 71211-71222

Clinical benefit from EGFR-TKI plus ginsenoside Rg3 in patients with advanced non-small cell lung cancer harboring EGFR active mutation Research Paper

Yan Li, Yanmei Wang, Kai Niu, Xiewan Chen, Liqin Xia, Dingxi Lu, Rui Kong, Zhengtang Chen, Yuzhong Duan, Jianguo Sun

Published Sep 16, 2016 · Vol. 7, No. 43 · pp. 70535-70545

CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy Research Paper

Fenne L. Komdeur, Maartje C.A. Wouters, Hagma H. Workel, Aline M. Tijans, Anouk L.J. Terwindt, Kim L. Brunekreeft, Annechien Plat, Harry G. Klip, Florine A. Eggink, Ninke Leffers, Wijnand Helfrich, Douwe F. Samplonius, Edwin Bremer, G. Bea A. Wisman, Toos Daemen, Evelien W. Duiker, Harry Hollema, Hans W. Nijman, Marco de Bruyn

Published Sep 16, 2016 · Vol. 7, No. 46 · pp. 75130-75144

SHP2 phosphatase as a novel therapeutic target for melanoma treatment Research Paper

Ruo-Yu Zhang, Zhi-Hong Yu, Lifan Zeng, Sheng Zhang, Yunpeng Bai, Jinmin Miao, Lan Chen, Jingwu Xie, Zhong-Yin Zhang

Published Sep 16, 2016 · Vol. 7, No. 45 · pp. 73817-73829

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network Research Paper

Elana J. Fertig, Hiroyuki Ozawa, Manjusha Thakar, Jason D. Howard, Luciane T. Kagohara, Gabriel Krigsfeld, Ruchira S. Ranaweera, Robert M. Hughes, Jimena Perez, SiÃ¢n Jones, Alexander V. Favorov, Jacob Carey, Genevieve Stein-Oâ€™Brien, Daria A. Gaykalova, Daria A. Gaykalova, Michael F. Ochs, Christine H. Chung

Published Sep 16, 2016 · Vol. 7, No. 45 · pp. 73845-73864

Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer Research Paper

Abderrahim El Guerrab, Mahchid Bamdad, Fabrice Kwiatkowski, Yves-Jean Bignon, FrÃ©dÃ©rique Penault-Llorca, Corinne Aubel

Published Sep 15, 2016 · Vol. 7, No. 45 · pp. 73618-73637

Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyloid light-chain amyloidosis Research Paper

Seok Jin Kim, Hyun-Tae Shin, Hae-Ock Lee, Nayoung K.D. Kim, Jae Won Yun, Jee Hyang Hwang, Kihyun Kim, Woong-Yang Park

Published Sep 15, 2016 · Vol. 7, No. 42 · pp. 68350-68359

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial Clinical Research Papers

Emilie Desportes, Mathilde Wagner, Maud Kamal, Anne Vincent Salomon, Gabrielle Deniziaut, GaÃ«lle Pierron, Etienne Rouleau, Thomas Jouffroy, Christophe Le Tourneau, Xavier Paoletti, Vincent Servois

Published Sep 15, 2016 · Vol. 8, No. 1 · pp. 1760-1773

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer Research Paper

Alexander Schinagl, Michael Thiele, Patrice Douillard, Dirk VÃ¶lkel, Lukas Kenner, Zahra Kazemi, Michael Freissmuth, Friedrich Scheiflinger, Randolf J. Kerschbaumer

Published Sep 12, 2016 · Vol. 7, No. 45 · pp. 73486-73496

Combination treatment including targeted therapy for advanced hepatocellular carcinoma Review

Jianzhen Lin, Liangcai Wu, Xue Bai, Yuan Xie, Anqiang Wang, Haohai Zhang, Xiaobo Yang, Xueshuai Wan, Xin Lu, Xinting Sang, Haitao Zhao

Published Sep 10, 2016 · Vol. 7, No. 43 · pp. 71036-71051

Identification of a structurally novel BTK mutation that drives ibrutinib resistance in CLL Research Paper

Shruti Sharma, Natalie Galanina, Ailin Guo, Jimmy Lee, Sabah Kadri, Charles Van Slambrouck, Bradley Long, Weige Wang, Mei Ming, Larissa V. Furtado, Jeremy P. Segal, Wendy Stock, Girish Venkataraman, Wei-Jen Tang, Pin Lu, Yue Lynn Wang

Published Sep 10, 2016 · Vol. 7, No. 42 · pp. 68833-68841

TumorNext: A comprehensive tumor profiling assay that incorporates high resolution copy number analysis and germline status to improve testing accuracy Research Paper

Phillip N. Gray, Huy Vuong, Pei Tsai, Hsaio-Mei Lu, Wenbo Mu, Vickie Hsuan, Jayne Hoo, Swati Shah, Lisa Uyeda, Susanne Fox, Harshil Patel, Mike Janicek, Sandra Brown, Lavinia Dobrea, Lawrence Wagman, Elizabeth Plimack, Ranee Mehra, Erica A. Golemis, Marijo Bilusic, Matthew Zibelman, Aaron Elliott

Published Sep 8, 2016 · Vol. 7, No. 42 · pp. 68206-68228

Oncogenic function and clinical implications of SLC3A2-NRG1 fusion in invasive mucinous adenocarcinoma of the lung Research Paper

Dong Hoon Shin, Donghoon Lee, Dong Wan Hong, Seung Hyun Hong, Jung-Ah Hwang, Byung Il Lee, Hye Jin You, Geon Kook Lee, In-Hoo Kim, Yeon-Su Lee, Ji-Youn Han

Published Sep 8, 2016 · Vol. 7, No. 43 · pp. 69450-69465

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma Research Paper

Christine M. Heske, Arnulfo Mendoza, Leah D. Edessa, Joshua T. Baumgart, Sunmin Lee, Jane Trepel, David A. Proia, Len Neckers, Lee J. Helman

Published Sep 6, 2016 · Vol. 7, No. 40 · pp. 65540-65552

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas Research Paper

Gabrielle Deniziaut, Jean Christophe Tille, FranÃ§ois-ClÃ©ment Bidard, Sophie Vacher, Anne Schnitzler, Walid Chemlali, Laurence Tremoulet, Laetitia Fuhrmann, Paul Cottu, Roman Rouzier, Ivan BiÃ¨che, Anne Vincent-Salomon

Published Sep 2, 2016 · Vol. 7, No. 45 · pp. 73337-73346

Quantification of nucleic acid quality in postmortem tissues from a cancer research autopsy program Research Paper

Jun Fan, Raya Khanin, Hitomi Sakamoto, Yi Zhong, Chelsea Michael, Derwin Pena, Breanna Javier, Laura D. Wood, Christine A. Iacobuzio-Donahue

Published Sep 2, 2016 · Vol. 7, No. 41 · pp. 66906-66921

Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers Research Paper

Published Sep 2, 2016 · Vol. 7, No. 42 · pp. 68546-68558

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy Research Paper

Fei Ma, Wenjie Zhu, Yanfang Guan, Ling Yang, Xuefeng Xia, Shanshan Chen, Qiao Li, Xiuwen Guan, Zongbi Yi, Haili Qian, Xin Yi, Binghe Xu

Published Sep 1, 2016 · Vol. 7, No. 40 · pp. 66020-66031

Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer Research Paper

Victoria Villaflor, Brian Won, Rebecca Nagy, Kimberly Banks, Richard B. Lanman, AmirAli Talasaz, Ravi Salgia

Published Sep 1, 2016 · Vol. 7, No. 41 · pp. 66880-66891

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts Research Paper

Beatriz Morancho, Mariano ZacarÃas-Fluck, Antonio Esgueva, Cristina BernadÃ³-Morales, Serena Di Cosimo, Aleix Prat, Javier CortÃ©s, JoaquÃn Arribas, Isabel T. Rubio

Published Sep 1, 2016 · Vol. 7, No. 42 · pp. 67956-67965

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Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma Research Paper

Clinical benefit from EGFR-TKI plus ginsenoside Rg3 in patients with advanced non-small cell lung cancer harboring EGFR active mutation Research Paper

CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy Research Paper

SHP2 phosphatase as a novel therapeutic target for melanoma treatment Research Paper

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network Research Paper

Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer Research Paper

Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyloid light-chain amyloidosis Research Paper

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial Clinical Research Papers

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer Research Paper

Combination treatment including targeted therapy for advanced hepatocellular carcinoma Review

Identification of a structurally novel BTK mutation that drives ibrutinib resistance in CLL Research Paper

TumorNext: A comprehensive tumor profiling assay that incorporates high resolution copy number analysis and germline status to improve testing accuracy Research Paper

Oncogenic function and clinical implications of SLC3A2-NRG1 fusion in invasive mucinous adenocarcinoma of the lung Research Paper

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma Research Paper

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas Research Paper

Quantification of nucleic acid quality in postmortem tissues from a cancer research autopsy program Research Paper

Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers Research Paper

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy Research Paper

Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer Research Paper

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma Research Paper

Clinical benefit from EGFR-TKI plus ginsenoside Rg3 in patients with advanced non-small cell lung cancer harboring EGFR active mutation Research Paper

CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy Research Paper

SHP2 phosphatase as a novel therapeutic target for melanoma treatment Research Paper

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network Research Paper

Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer Research Paper

Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyloid light-chain amyloidosis Research Paper

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial Clinical Research Papers

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer Research Paper

Combination treatment including targeted therapy for advanced hepatocellular carcinoma Review

Identification of a structurally novel BTK mutation that drives ibrutinib resistance in CLL Research Paper

TumorNext: A comprehensive tumor profiling assay that incorporates high resolution copy number analysis and germline status to improve testing accuracy Research Paper

Oncogenic function and clinical implications of SLC3A2-NRG1 fusion in invasive mucinous adenocarcinoma of the lung Research Paper

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma Research Paper

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas Research Paper

Quantification of nucleic acid quality in postmortem tissues from a cancer research autopsy program Research Paper

Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers Research Paper

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy Research Paper

Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer Research Paper

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts Research Paper