The Oncosearch | Oncotarget

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer Research Paper

Hassan Ashktorab, Pooneh Mokarram, Hamed Azimi, Hasti Olumi, Sudhir Varma, Michael L. Nickerson, Hassan Brim

Published Dec 16, 2016 · Vol. 8, No. 5 · pp. 7852-7866

Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes Research Paper

Emily Kolyvas, Michael Rudloff, Marianne Poruchynsky, Rebekah Landsman, Kevin Hollevoet, David Venzon, Christine Alewine

Published Dec 16, 2016 · Vol. 8, No. 6 · pp. 9189-9199

Management of salivary gland carcinomas - a review Research Paper

Xiaoli Wang, Yijun Luo, Minghuan Li, Hongjiang Yan, Mingping Sun, Tingyong Fan

Published Dec 15, 2016 · Vol. 8, No. 3 · pp. 3946-3956

Leptin-Notch signaling axis is involved in pancreatic cancer progression Research Paper

Adriana Harbuzariu, Antonio Rampoldi, Danielle S Daley-Brown, Pierre Candelaria, Tia L Harmon, Crystal C Lipsey, Derrick J Beech, Alexander Quarshie, Gabriela Oprea Ilies, Ruben R Gonzalez-Perez

Published Dec 15, 2016 · Vol. 8, No. 5 · pp. 7740-7752

The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins Research Paper

Liangshun You, Hui Liu, Jian Huang, Wanzhuo Xie, Jueying Wei, Xiujin Ye, Wenbin Qian

Published Dec 15, 2016 · Vol. 8, No. 5 · pp. 7777-7790

Novel phenotypes of NF1 patients from unrelated Chinese families with tibial pseudarthrosis and anemia Clinical Research Papers

Santasree Banerjee, Dongzhu Lei, Shengran Liang, Li Yang, Saijun Liu, Zhu Wei, Jian Ping Tang

Published Dec 14, 2016 · Vol. 8, No. 24 · pp. 39695-39702

Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer Research Paper

Bernardo Queralt, Elisabet CuyÃ s, Joaquim Bosch-Barrera, Anna Massaguer, Rafael de Llorens, BegoÃ±a Martin-Castillo, Joan Brunet, Ramon Salazar, Javier A. Menendez

Published Dec 13, 2016 · Vol. 7, No. 50 · pp. 82185-82199

Guide to detecting epidermal growth factor receptor (EGFR) mutations in ctDNA of patients with advanced non-small-cell lung cancer Review

Nicola Normanno, Marc G. Denis, Kenneth S. Thress, Marianne Ratcliffe, MartinÂ Reck

Published Dec 12, 2016 · Vol. 8, No. 7 · pp. 12501-12516

Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate Research Paper

Jessica L. Rausch, Sergei Boichuk, Areej A. Ali, Sneha S. Patil, Lijun Liu, Donna M. Lee, Matthew F. Brown, Kathleen R. Makielski, Ying Liu, Takahiro Taguchi, Shih-Fan Kuan, Anette Duensing

Published Dec 10, 2016 · Vol. 8, No. 3 · pp. 4471-4483

Detection of ALK rearrangements in lung cancer patients using a homebrew PCR assay Research Paper

Hui Yu, JianHua Chang, Fang Liu, Qifeng Wang, YongMing Lu, ZhuanXu Zhang, Jiabing Shen, Qing Zhai, Xia Meng, Jialei Wang, Xun Ye

Published Dec 10, 2016 · Vol. 8, No. 5 · pp. 7722-7728

VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers Research Paper

RubÃ©n A. BartolomÃ©, SofÃa Torres, Soledad Isern de Val, Beatriz Escudero-Paniagua, Eva CalviÃ±o, JoaquÃn TeixidÃ³, J. Ignacio Casal

Published Dec 9, 2016 · Vol. 8, No. 1 · pp. 215-227

HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs) Research Paper

Sonia Paget, Marion Dubuissez, Vanessa Dehennaut, Joe Nassour, Brennan T. Harmon, Nathalie Spruyt, Ingrid Loison, Corinne Abbadie, Brian R. Rood, Dominique Leprince

Published Dec 7, 2016 · Vol. 8, No. 2 · pp. 2916-2935

The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus Research Paper

Ramiro VÃ¡zquez, MarÃa E. Riveiro, Lucile Astorgues-Xerri, Elodie Odore, Keyvan Rezai, Eugenio Erba, NicolÃ² Panini, Andrea Rinaldi, Ivo Kwee, Luca Beltrame, Mohamed Bekradda, Esteban Cvitkovic, Francesco Bertoni, Roberta Frapolli, Maurizio D'Incalci

Published Dec 7, 2016 · Vol. 8, No. 5 · pp. 7598-7613

Toward the use of precision medicine for the treatment of head and neck squamous cell carcinoma Research Paper

Wang Gong, Yandi Xiao, Zihao Wei, Yao Yuan, Min Qiu, Chongkui Sun, Xin Zeng, Xinhua Liang, Mingye Feng, Qianming Chen Chen

Published Dec 4, 2016 · Vol. 8, No. 2 · pp. 2141-2152

An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high EGFR gene copy number Clinical Research Papers

Ewa Szutowicz-ZieliÅ„ska, Krzysztof Konopa, Anna Kowalczyk, MaÅ‚gorzata Suszko-KaÅ¼arnowicz, Renata Duchnowska, Aleksandra SzczÄ™sna, Magdalena Ratajska, Aleksander Sowa, Janusz Limon, Wojciech Biernat, Tomasz Burzykowski, Jacek Jassem, RafaÅ‚ Dziadziuszko

Published Dec 4, 2016 · Vol. 8, No. 10 · pp. 17270-17278

The association between clinical prognostic factors and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer patients: a retrospective assessment of 94 cases with EGFR mutations Research Paper

Jing-Hui Lin, Dong Lin, Ling Xu, Qiang Wang, Hui-Hua Hu, Hai-Peng Xu, Zhi-Yong He

Published Dec 3, 2016 · Vol. 8, No. 2 · pp. 3412-3421

Developmental therapeutics for inflammatory breast cancer: Biology and translational directions Review

Ricardo Costa, Cesar A. Santa-Maria, Giovanna Rossi, Benedito A. Carneiro, Young Kwang Chae, William J. Gradishar, Francis J. Giles, Massimo Cristofanilli

Published Dec 2, 2016 · Vol. 8, No. 7 · pp. 12417-12432

The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors Research Paper

Hazel A. Rogers, Jasper Estranero, Keshni Gudka, Richard G. Grundy

Published Dec 2, 2016 · Vol. 8, No. 2 · pp. 2083-2095

Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma Research Paper

Maj Rabjerg, Barbara Guerra, Aida OlivÃ¡n-Viguera, Minne Line Nedergaard Mikkelsen, Ralf KÃ¶hler, Olaf-Georg Issinger, Niels Marcussen

Published Nov 29, 2016 · Vol. 8, No. 1 · pp. 1613-1627

Oncogenic secretory clusterin in hepatocellular carcinoma: Expression at early staging and emerging molecular target Research Paper

Wenjie Zheng, Min Yao, Qi Qian, Wenli Sai, Liwei Qiu, Junling Yang, Wei Wu, Zhizhen Dong, Dengfu Yao

Published Nov 29, 2016 · Vol. 8, No. 32 · pp. 52321-52332

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Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer Research Paper

Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes Research Paper

Management of salivary gland carcinomas - a review Research Paper

Leptin-Notch signaling axis is involved in pancreatic cancer progression Research Paper

The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins Research Paper

Novel phenotypes of NF1 patients from unrelated Chinese families with tibial pseudarthrosis and anemia Clinical Research Papers

Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer Research Paper

Guide to detecting epidermal growth factor receptor (EGFR) mutations in ctDNA of patients with advanced non-small-cell lung cancer Review

Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate Research Paper

Detection of ALK rearrangements in lung cancer patients using a homebrew PCR assay Research Paper

VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers Research Paper

HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs) Research Paper

The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus Research Paper

Toward the use of precision medicine for the treatment of head and neck squamous cell carcinoma Research Paper

An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high EGFR gene copy number Clinical Research Papers

The association between clinical prognostic factors and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer patients: a retrospective assessment of 94 cases with EGFR mutations Research Paper

Developmental therapeutics for inflammatory breast cancer: Biology and translational directions Review

The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors Research Paper

Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma Research Paper

Oncogenic secretory clusterin in hepatocellular carcinoma: Expression at early staging and emerging molecular target Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer Research Paper

Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes Research Paper

Management of salivary gland carcinomas - a review Research Paper

Leptin-Notch signaling axis is involved in pancreatic cancer progression Research Paper

The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins Research Paper

Novel phenotypes of NF1 patients from unrelated Chinese families with tibial pseudarthrosis and anemia Clinical Research Papers

Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer Research Paper

Guide to detecting epidermal growth factor receptor (EGFR) mutations in ctDNA of patients with advanced non-small-cell lung cancer Review

Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate Research Paper

Detection of ALK rearrangements in lung cancer patients using a homebrew PCR assay Research Paper

VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers Research Paper

HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs) Research Paper

The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus Research Paper

Toward the use of precision medicine for the treatment of head and neck squamous cell carcinoma Research Paper

An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high EGFR gene copy number Clinical Research Papers

The association between clinical prognostic factors and epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) efficacy in advanced non-small-cell lung cancer patients: a retrospective assessment of 94 cases with EGFR mutations Research Paper

Developmental therapeutics for inflammatory breast cancer: Biology and translational directions Review

The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors Research Paper

Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma Research Paper

Oncogenic secretory clusterin in hepatocellular carcinoma: Expression at early staging and emerging molecular target Research Paper