The Oncosearch | Oncotarget

Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma Research Paper

Valerie B. Sampson, Nancy S. Vetter, Wendong Zhang, Pratima U. Patil, Robert W. Mason, Erika George, Richard Gorlick, Edward A. Kolb

Published Nov 15, 2016 · Vol. 7, No. 52 · pp. 86594-86607

Synthetic paclitaxel-octreotide conjugate reversing the resistance of A2780/Taxol to paclitaxel in xenografted tumor in nude mice Research Paper

Xi Chen, Xiao-Yu Zhang, Yang Shen, Li-Li Fan, Mu-Lan Ren, Yong-Ping Wu

Published Nov 4, 2016 · Vol. 7, No. 50 · pp. 83451-83461

Stimulation of the toll-like receptor 3 promotes metabolic reprogramming in head and neck carcinoma cells Research Paper

Mathieu Veyrat, SylvÃ¨re Durand, Marion Classe, Tanja Matijevic Glavan, Natalie Oker, Nikiforos-Ioannis Kapetanakis, Xiaojun Jiang, Aurore Gelin, Philippe Herman, Odile Casiraghi, David Zagzag, David Enot, Pierre Busson, Benjamin VÃ©rillaud

Published Oct 25, 2016 · Vol. 7, No. 50 · pp. 82580-82593

CDDO-Me reveals USP7 as a novel target in ovarian cancer cells Research Paper

Dongjun Qin, Weiwei Wang, Hu Lei, Hao Luo, Haiyan Cai, Caixia Tang, Yunzhao Wu, Yingying Wang, Jin Jin, Weilie Xiao, Tongdan Wang, Chunmin Ma, Hanzhang Xu, Jinfu Zhang, Fenghou Gao, Ying-Li Wu

Published Oct 21, 2016 · Vol. 7, No. 47 · pp. 77096-77109

DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation Research Paper

Francesca Megiorni, Simona Camero, Simona Ceccarelli, Heather P. McDowell, Olga Mannarino, Francesco Marampon, Barry Pizer, Rajeev Shukla, Antonio Pizzuti, Cinzia Marchese, Anna Clerico, Carlo Dominici

Published Oct 15, 2016 · Vol. 7, No. 48 · pp. 79342-79356

Androgen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles Review

David T. Hoang, Kenneth A. Iczkowski, Deepak Kilari, William See, Marja T. Nevalainen

Published Oct 10, 2016 · Vol. 8, No. 2 · pp. 3724-3745

SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis Research Paper

Kaname Akamata, Jun Wei, Mitra Bhattacharyya, Paul Cheresh, Michael Y. Bonner, Jack L. Arbiser, Kirtee Raparia, Mahesh P. Gupta, David W. Kamp, John Varga

Published Oct 6, 2016 · Vol. 7, No. 43 · pp. 69321-69336

Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma Research Paper

Lan V. Pham, Jerry L. Bryant, Richard Mendez, Juan Chen, Archito T. Tamayo, Zijun Y. Xu-Monette, Ken H. Young, Ganiraju C. Manyam, David Yang, David Yang, L. Jeffrey Medeiros, Richard J. Ford

Published Oct 3, 2016 · Vol. 7, No. 49 · pp. 80599-80611

The andean anticancer herbal product BIRM causes destabilization of androgen receptor and induces caspase-8 mediated-apoptosis in prostate cancer Research Paper

Nagarajarao Shamaladevi, Shinako Araki, Dominic A. Lyn, Rajnikanth Ayyathurai, Jie Gao, Vinata B. Lokeshwar, Hugo Navarrete, Bal L. Lokeshwar

Published Oct 1, 2016 · Vol. 7, No. 51 · pp. 84201-84213

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation Research Paper

Yan Long, Wen-Bin Tsai, Jeffrey T. Chang, Marcos Estecio, Medhi Wangpaichitr, Naramol Savaraj, Lynn G. Feun, Helen H.W. Chen, Macus Tien Kuo

Published Sep 28, 2016 · Vol. 7, No. 50 · pp. 82658-82670

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas Research Paper

MaÅ‚gorzata CzyÅ¼, Monika Toma, Anna Gajos-Michniewicz, Kinga Majchrzak, Grazyna Hoser, Janusz Szemraj, Margaret Nieborowska-Skorska, Phil Cheng, Daniel Gritsyuk, Mitchell Levesque, Reinhard Dummer, Tomasz Sliwinski, Tomasz Skorski

Published Sep 27, 2016 · Vol. 7, No. 46 · pp. 75551-75560

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids Research Paper

Anindita Dutta, David N. Potier, Michael J. Walker, Oliver J. Gray, Catriona Parker, Mark Holland, Andrew J.K. Williamson, Andrew Pierce, Richard D. Unwin, Shekhar Krishnan, Vaskar Saha, Anthony D. Whetton

Published Sep 23, 2016 · Vol. 7, No. 43 · pp. 70822-70831

Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma Research Paper

Jan-Gowth Chang, Chia-Cheng Chen, Yi-Ying Wu, Ting-Fang Che, Yi-Syuan Huang, Kun-Tu Yeh, Grace S. Shieh, Pan-Chyr Yang

Published Sep 15, 2016 · Vol. 7, No. 45 · pp. 73664-73680

Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation Research Paper

Aoli Wang, Xiao-E Yan, Hong Wu, Wenchao Wang, Chen Hu, Cheng Chen, Zheng Zhao, Peng Zhao, Xixiang Li, Li Wang, Beilei Wang, Zi Ye, Jinhua Wang, Chu Wang, Wei Zhang, Nathanael S. Gray, Ellen L. Weisberg, Liang Chen, Jing Liu, Cai-Hong Yun, Qingsong Liu

Published Sep 10, 2016 · Vol. 7, No. 43 · pp. 69760-69769

Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the Apc^Min/+ model Research Paper

Makiko Kawaguchi, Koji Yamamoto, Ai Kanemaru, Hiroyuki Tanaka, Kazuo Umezawa, Tsuyoshi Fukushima, Hiroaki Kataoka

Published Sep 6, 2016 · Vol. 7, No. 42 · pp. 68614-68622

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer Priority Research Paper

Amanda R. Oran, Clare M. Adams, Xiao-yong Zhang, Victoria J. Gennaro, Harla K. Pfeiffer, Hestia S. Mellert, Hans E. Seidel, Kirsten Mascioli, Jordan Kaplan, Mahmoud R. Gaballa, Chen Shen, Isidore Rigoutsos, Michael P. King, Justin L. Cotney, Jamie J. Arnold, Suresh D. Sharma, Ubaldo E. Martinez-Outschoorn, Christopher R. Vakoc, Lewis A. Chodosh, James E. Thompson, James E. Bradner, Craig E. Cameron, Gerald S. Shadel, Christine M. Eischen, Steven B. McMahon

Published Aug 31, 2016 · Vol. 7, No. 45 · pp. 72395-72414

The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas Priority Research Paper

Aleco Dâ€™Andrea, Ilaria Gritti, Paola Nicoli, Marco Giorgio, Mirko Doni, Annalisa Conti, Valerio Bianchi, Lucia Casoli, Arianna SabÃ², Alexandre Mironov, Galina V. Beznoussenko, Bruno Amati

Published Aug 31, 2016 · Vol. 7, No. 45 · pp. 72415-72430

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients Research Paper

Gijs G. Zom, Marij J.P. Welters, Nikki M. Loof, Renske Goedemans, SinÃ©ad Lougheed, Rob R.P.M. Valentijn, Maarten L. Zandvliet, Nico J. Meeuwenoord, Cornelis J.M. Melief, Tanja D. de Gruijl, Gijsbert A. Van der Marel, Dmitri V. Filippov, Ferry Ossendorp, Sjoerd H. Van der Burg

Published Aug 23, 2016 · Vol. 7, No. 41 · pp. 67087-67100

Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor Research Paper

Megan E. Zavorka, Christopher M. Connelly, Rosslyn Grosely, Richard G. MacDonald

Published Aug 22, 2016 · Vol. 7, No. 38 · pp. 62386-62410

Sensitizing thermochemotherapy with a PARP1-inhibitor Research Paper

Arlene L. Oei, Lianne E.M. Vriend, Caspar M. van Leeuwen, Hans M. Rodermond, Rosemarie ten Cate, Anneke M. Westermann, Lukas J.A. Stalpers, Johannes Crezee, Roland Kanaar, H. Petra Kok, Przemek M. Krawczyk, Nicolaas A.P. Franken

Published Aug 19, 2016 · Vol. 8, No. 10 · pp. 16303-16312

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Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma Research Paper

Synthetic paclitaxel-octreotide conjugate reversing the resistance of A2780/Taxol to paclitaxel in xenografted tumor in nude mice Research Paper

Stimulation of the toll-like receptor 3 promotes metabolic reprogramming in head and neck carcinoma cells Research Paper

CDDO-Me reveals USP7 as a novel target in ovarian cancer cells Research Paper

DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation Research Paper

Androgen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles Review

SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis Research Paper

Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma Research Paper

The andean anticancer herbal product BIRM causes destabilization of androgen receptor and induces caspase-8 mediated-apoptosis in prostate cancer Research Paper

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation Research Paper

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas Research Paper

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids Research Paper

Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma Research Paper

Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation Research Paper

Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the Apc^Min/+ model Research Paper

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer Priority Research Paper

The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas Priority Research Paper

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients Research Paper

Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor Research Paper

Sensitizing thermochemotherapy with a PARP1-inhibitor Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma Research Paper

Synthetic paclitaxel-octreotide conjugate reversing the resistance of A2780/Taxol to paclitaxel in xenografted tumor in nude mice Research Paper

Stimulation of the toll-like receptor 3 promotes metabolic reprogramming in head and neck carcinoma cells Research Paper

CDDO-Me reveals USP7 as a novel target in ovarian cancer cells Research Paper

DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation Research Paper

Androgen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles Review

SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis Research Paper

Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma Research Paper

The andean anticancer herbal product BIRM causes destabilization of androgen receptor and induces caspase-8 mediated-apoptosis in prostate cancer Research Paper

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation Research Paper

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas Research Paper

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids Research Paper

Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma Research Paper

Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation Research Paper

Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the ApcMin/+ model Research Paper

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer Priority Research Paper

The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas Priority Research Paper

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients Research Paper

Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor Research Paper

Sensitizing thermochemotherapy with a PARP1-inhibitor Research Paper

Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the Apc^Min/+ model Research Paper