The Oncosearch | Oncotarget

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Jennifer Wheler, Gerald Falchook, Apostolia M. Tsimberidou, David Hong, Aung Naing, Sarina Piha-Paul, Su S. Chen, John Heymach, Siqing Fu, Su S. Chen, Bettzy Stephen, Jansina Y. Fok, Filip Janku, Razelle Kurzrock

Published Jun 4, 2013 · Vol. 4, No. 5 · pp. 772-784

Keywords: EGFR mutation, EGFR wild-type, non-small cell lung cancer, phase I trials, resistance, squamous cell

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

Claudia A. Benavente, Justina D. McEvoy, David Finkelstein, Lei Wei, Guolian Kang, Yong-Dong Wang, Geoffrey Neale, Susan Ragsdale, Virginia Valentine, Armita Bahrami, Jamshid Temirov, Stanley Pounds, Jinghui Zhang, Michael A. Dyer

Published Jun 1, 2013 · Vol. 4, No. 6 · pp. 844-859

Keywords: retinoblastoma, RB1, epigenetics

Single circulating tumor cell sequencing for monitoring Editorial

Martina Auer, Ellen Heitzer, Peter Ulz, Jochen B. Geigl, Michael R Speicher

Published May 10, 2013 · Vol. 4, No. 6 · pp. 812-813

Keywords: circulating tumor cells, personalized medicine, disease monitoring, next-generation sequencing

Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene Research Paper

Arnaldur Hall, Kathrine Damm Meyle, Marina Krarup Lange, Martin Klima, May Sanderhoff, Christina Dahl, Cecilie Abildgaard, Katrine Thorup, Seyed Moein Moghimi, Per Bo Jensen, Jiri Bartek, Per Guldberg, Claus Christensen

Published Apr 8, 2013 · Vol. 4, No. 4 · pp. 584-599

Keywords: Oncogene addiction, melanoma, V600EBRAF, the Warburg effect, glycolysis, oxidative phosphorylation

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Chetan Bettegowda, Nishant Agrawal, Yuchen Jiao, Yuxuan Wang, Laura D. Wood, Fausto J. Rodriguez, Ralph H. Hruban, Gary L. Gallia, Zev A. Binder, Callen J. Riggins, Vafi Salmasi, Gregory J. Riggins, Zachary J. Reitman, Ahmed Rasheed, Stephen Keir, Sueli Shinjo, Suely Marie, Roger McLendon, George Jallo, Bert Vogelstein, Darrell Bigner, Hai Yan, Kenneth W. Kinzler, Nickolas Papadopoulos

Published Apr 6, 2013 · Vol. 4, No. 4 · pp. 572-583

Keywords: CNS tumors, PXA, GBM, ependymoma, exomic sequencing, BRAF, mTOR

Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression Research Paper

Joan C Delto, Takashi Kobayashi, Mitchell C Benson, James McKiernan, Cory Abate-Shen

Published Feb 25, 2013 · Vol. 4, No. 2 · pp. 269-276

Keywords: Non-muscle invasive bladder cancer, intravesical therapy, genetically engineered mouse models, preclinical studies

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Meiyun Fan, Susan R. Pfeffer, Henry T. Lynch, Pamela Cassidy, Sancy Leachman, Lawrence M. Pfeffer, Levy Kopelovich

Published Jan 19, 2013 · Vol. 4, No. 1 · pp. 128-141

Keywords: Familial Melanoma, gene expression, CDKN2A, p16, Mutations, Melanoma

Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCIâ€™s provocative questions Research Perspective

Mikhail V. Blagosklonny

Published Dec 30, 2012 · Vol. 3, No. 12 · pp. 1711-1724

SOCS1 Mutation Subtypes Predict Divergent Outcomes in Diffuse Large B-Cell Lymphoma (DLBCL) Patients Research Paper

Birgit Schif, Jochen K Lennerz, Christian W Kohler, Markus Kreuz, Stefan Bentink, Ingo Melzner, Olga Ritz, Lorenz TrÃ¼mper, Markus LÃ¶ffler, Rainer Spang, Peter MÃ¶ller

Published Dec 9, 2012 · Vol. 4, No. 1 · pp. 35-47

Keywords: biomarker, SOCS, JAK/STAT, GCB

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans Research Paper

Kyle M. Walsh, Christopher I. Amos, Angela S. Wenzlaff, Ivan P. Gorlov, Jennette D. Sison, Xifeng Wu, Margaret R. Spitz, Helen M. Hansen, Emily Y. Lu, Chongjuan Wei, Huifeng Zhang, Wei Chen, Stacy M. Lloyd, Marsha L. Frazier, Paige M. Bracci, Michael F. Seldin, Margaret R. Wrensch, Ann G. Schwartz, John K. Wiencke

Published Nov 16, 2012 · Vol. 3, No. 11 · pp. 1428-1438

Keywords: Lung cancer, nicotine dependence, African-Americans, genetic association

Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer Research Paper

AKWASI AGYEMAN, Tapati Mazumdar, Janet A Houghton

Published Aug 20, 2012 · Vol. 3, No. 8 · pp. 854-868

Keywords: Hedgehog, GLI1/2 inhibition, GANT61, DNA damage, colon cancer

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients Research Paper

Elias Bou Samra, Bernard Klein, ThÃ©rÃ¨se Commes, Jerome Moreaux

Published Aug 18, 2012 · Vol. 3, No. 8 · pp. 824-832

Keywords: gene expression-based risk score, cytogenetically normal-acute myeloid leukemia, prognostic gene signature, EVI1 expression

Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts Brief Reports

SÃlvia CufÃ, Bruna Corominas-Faja, Alejandro Vazquez-Martin, Cristina Oliveras-Ferraros, Joan Dorca, Joaquim Bosch-Barrera, BegoÃ±a Martin-Castillo, Javier A Menendez

Published May 4, 2012 · Vol. 3, No. 4 · pp. 395-398

Keywords: metformin, trastuzumab, HER2, cancer stem cells, breast cancer

Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing Methodological Reports

Renee C. Tschumper, Yan W. Asmann, Asif Hossain, Paul M. Huddleston, Xiaosheng Wu, Angela Dispenzieri, Bruce W. Eckloff, Diane F. Jelinek

Published Apr 20, 2012 · Vol. 3, No. 4 · pp. 502-513

Keywords: IGHV, multiple myeloma, massively parallel sequencing

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1 Research Paper

Julie S. Barber-Rotenberg, Saravana P. Selvanathan, Yali Kong, Hayriye V. Erkizan, Tara M. Snyder, S. Peter Hong, Christina L. Kobs, Natalie L. South, Steven Summer, Philip J. Monroe, Maksymilian Chruszcz, Veselin Dobrev, Perrer N. Tosso, Lauren J. Scher, Wladek Minor, Milton L. Brown, Steven J. Metallo, Aykut Ãœren, Jeffrey A. Toretsky

Published Feb 29, 2012 · Vol. 3, No. 2 · pp. 172-182

Will PI3K pathway inhibitors be effective as single agents in patients with cancer? Research Perspective

Joan T. Garrett, Anindita Chakrabarty, Carlos L. Arteaga

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 1314-1321

A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA) Research Paper

Sangeeta Ray Banerjee, Mrudula Pullambhatla, Hassan Shallal, Ala Lisok, Ronnie C. Mease, Martin G. Pomper

Published Dec 29, 2011 · Vol. 2, No. 12 · pp. 1244-1253

Keywords: Prostate-specific membrane antigen (PSMA), NAALADase, bivalent urea inhibitor, molecular imaging, multivalency, SPECT imaging

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Dannis Gilbert Van Vuurden, Esther Hulleman, Olga L.M. Meijer, Laurine E. Wedekind, Marcel Kool, Hendrik Witt, W. Peter Vandertop, Thomas WÃ¼rdinger, David P. Noske, Gertjan J.L. Kaspers, Jacqueline Cloos

Published Dec 15, 2011 · Vol. 2, No. 12 · pp. 984-996

Keywords: PARP, radiation, medulloblastoma, ependymoma, glioma, pediatric

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper

Olivier LaRochelle, Sarah Bertoli, FranÃ§ois Vergez, Jean Emmanuel Sarry, VÃ©ronique Mansat-De Mas, Sophie Dobbelstein, Nicole Dastugue, Anne-Claire Strzelecki, Cindy Cavelier, Laurent Creancier, Arnaud Pillon, Anna Kruczynski, Cecile Demur, Audrey Sarry, FranÃ§oise Huguet, Anne Huynh, Christian RÃ©cher, Eric Delabesse

Published Nov 9, 2011 · Vol. 2, No. 11 · pp. 850-861

Keywords: leukemia, DNMT3A, anthracyclins, idarubicin, AML

Systemic use of tumor necrosis factor alpha as an anticancer agent Review

Nicholas J. Roberts, Shibin Zhou, Luis A. Diaz, Matthias Holdhoff

Published Oct 27, 2011 · Vol. 2, No. 10 · pp. 739-751

Keywords: TNF-Î±, systemic, therapy

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Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

Single circulating tumor cell sequencing for monitoring Editorial

Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene Research Paper

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression Research Paper

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCIâ€™s provocative questions Research Perspective

SOCS1 Mutation Subtypes Predict Divergent Outcomes in Diffuse Large B-Cell Lymphoma (DLBCL) Patients Research Paper

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans Research Paper

Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer Research Paper

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients Research Paper

Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts Brief Reports

Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing Methodological Reports

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1 Research Paper

Will PI3K pathway inhibitors be effective as single agents in patients with cancer? Research Perspective

A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA) Research Paper

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper

Systemic use of tumor necrosis factor alpha as an anticancer agent Review

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European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

Single circulating tumor cell sequencing for monitoring Editorial

Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene Research Paper

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression Research Paper

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCIâ€™s provocative questions Research Perspective

SOCS1 Mutation Subtypes Predict Divergent Outcomes in Diffuse Large B-Cell Lymphoma (DLBCL) Patients Research Paper

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans Research Paper

Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer Research Paper

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients Research Paper

Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts Brief Reports

Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing Methodological Reports

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1 Research Paper

Will PI3K pathway inhibitors be effective as single agents in patients with cancer? Research Perspective

A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA) Research Paper

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper

Systemic use of tumor necrosis factor alpha as an anticancer agent Review