The Oncosearch | Oncotarget

Reduced ING1 levels in breast cancer promotes metastasis Research Paper

Satbir Thakur, Arvind K. Singla, Jie Chen, Uyen Tran, Yang Yang, Carolina Salazar, Anthony Magliocco, Alexander Klimowicz, Frank R. Jirik, Karl Riabowol

Published May 19, 2014 · Vol. 5, No. 12 · pp. 4244-4256

Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma Research Paper

Chul-Kee Park, Se-Hoon Lee, Ji Young Kim, Ja Eun Kim, Tae Min Kim, Soon-Tae Lee, Seung Hong Choi, Sung-Hye Park, Il Han Kim

Published May 14, 2014 · Vol. 5, No. 10 · pp. 3399-3407

Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis Research Paper

Sudjit Luanpitpong, Liying Wang, Todd A. Stueckle, William Tse, Yi Charlie Chen, Yon Rojanasakul

Published May 8, 2014 · Vol. 5, No. 11 · pp. 3541-3554

The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors Research Paper

Tun Kiat Ko, Charles T.H. Chuah, John W.J. Huang, King-Pan Ng, S. Tiong Ong

Published Apr 27, 2014 · Vol. 5, No. 19 · pp. 9033-9038

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways Priority Research Paper

Anne Y. Saiki, Sean Caenepeel, Dongyin Yu, Julie A. Lofgren, Tao Osgood, Rebecca Robertson, Jude Canon, Cheng Su, Adrie Jones, Xiaoning Zhao, Chetan Deshpande, Marc Payton, Jebediah Ledell, Paul E. Hughes, Jonathan D. Oliner

Published Apr 23, 2014 · Vol. 5, No. 8 · pp. 2030-2043

miR-17 inhibition enhances the formation of kidney cancer spheres with stem cell/ tumor initiating cell properties Research Paper

Zsuzsanna Lichner, Carol Saleh, Venkateswaran Subramaniam, Annetta Seivwright, Gerald Joseph Prudâ€™homme, George Makram Yousef

Published Apr 16, 2014 · Vol. 6, No. 8 · pp. 5567-5581

Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another â€œdouble hitâ€ lymphoma with very poor outcome? Research Paper

Fazila Asmar, Christoffer Hother, Gorjan Kulosman, Marianne Bach Treppendahl, Helene Myrtue Nielsen, Ulrik Ralfkiaer, Anja Pedersen, Michael Boe MÃ¸ller, Elisabeth Ralfkiaer, Peter de Nully Brown, Kirsten GrÃ¸nbÃ¦k

Published Mar 31, 2014 · Vol. 5, No. 7 · pp. 1912-1925

The immunocytokine NHS-IL12 as a potential cancer therapeutic Research Paper

Jonathan Fallon, Robert Tighe, Giorgio Kradjian, Wilson Guzman, Anna Bernhardt, Berend Neuteboom, Yan Lan, Helen Sabzevari, Jeffrey Schlom, John W. Greiner

Published Mar 24, 2014 · Vol. 5, No. 7 · pp. 1869-1884

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

Alboukadel Kassambara, Claire Gourzones-Dmitriev, Surinder Sahota, Thierry RÃ¨me, JÃ©rÃ´me Moreaux, Hartmut Goldschmidt, Angelos Constantinou, Phillipe Pasero, Dirk Hose, Bernard Klein

Published Feb 24, 2014 · Vol. 5, No. 9 · pp. 2487-2498

Keywords: DNA repair, Multiple Myeloma, prognosis

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Shigeru Kawabata, Chun-Te Chiang, Junji Tsurutani, Hideaki Shiga, Matthew L. Arwood, Takefumi Komiya, Joell J. Gills, Regan M. Memmott, Phillip A. Dennis

Published Feb 16, 2014 · Vol. 5, No. 4 · pp. 1062-1070

Keywords: Rapamycin, Pemetrexed, Drug synergy, mTOR, Thymidylate Synthase, Lung Cancer

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Arnau Montraveta, Silvia Xargay-Torrent, MÃ³nica LÃ³pez-Guerra, Laia Rosich, Patricia PÃ©rez-GalÃ¡n, Itziar Salaverria, Silvia BeÃ, Susana G. Kalko, MercÃ¨ de Frias, Clara CampÃ s, GaÃ«l RouÃ©, Dolors Colomer

Published Jan 25, 2014 · Vol. 5, No. 3 · pp. 726-739

Keywords: Acadesine, rituximab, mantle cell lymphoma, xenograft mouse model

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Adrienne L. Watson, Bryant J. Keller, Kyle A. Williams, Namrata N. Damle, Samuel J. Finnerty, Leah K. Anderson, Andrew D. Greeley, Vincent W. Keng, Eric P. Rahrmann, Amanda L. Halfond, Natasha M. Powell, Margaret H. Collins, Tilat Rizvi, Christopher L. Moertel, Nancy Ratner, David A. Largaespada

Published Jan 20, 2014 · Vol. 5, No. 6 · pp. 1502-1514

Keywords: Malignant peripheral nerve sheath tumors, plexiform neurofibromas, Schwann cells, neurofibromatosis type 1 syndrome, neurofibromin 1, PI3K/AKT/mTOR signaling, MAPK signaling, targeted therapies, genetically engineered mouse models, combination therapy

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

Aline Renneville, Raouf Ben Abdelali, Sylvie Chevret, Olivier Nibourel, Meyling Cheok, Cecile Pautas, Remy Dulery, Thomas Boyer, Jean-Michel Cayuela, Sandrine Hayette, Emmanuel Raffoux, Hassan Farhat, Nicolas Boissel, Christine Terre, Herve Dombret, Sylvie Castaigne, Claude Preudhomme

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 916-932

Keywords: acute myeloid leukemia, SNP array lesions, gene mutations, gemtuzumab ozogamicin, prognosis

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines Research Paper

Ilaria Sciamanna, Alberto Gualtieri, Cristina Cossetti, Emanuele Felice Osimo, Manuela Ferracin, Gianfranco Macchia, Eleonora Arico, Gianni Prosseda, Patrizia Vitullo, Tom Misteli, Corrado Spadafora

Published Oct 14, 2013 · Vol. 4, No. 12 · pp. 2271-2287

Keywords: LINE-1 retrotransposons, reverse transcriptase, transcriptome, miRNAs, DNA:RNA hybrids, cancer genome, reverse transcriptase inhibitor.

Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer Research Paper

Leigh Ellis, ShengYu Ku, Swathi Ramakrishnan, Elena Lasorsa, Gizzou Azabdaftari, Alejandro Godoy, Roberto Pili

Published Sep 27, 2013 · Vol. 4, No. 12 · pp. 2225-2236

Keywords: prostate cancer, BEZ235, panobinostat, DNA damage, ATM, therapy

Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Research Paper

Raffaella Spina, Gessica Filocamo, Enrico Iaccino, Stefania Scicchitano, Michela Lupia, Emanuela Chiarella, Tiziana Mega, Francesca Bernaudo, Daniela Pelaggi, Maria Mesuraca, Simonetta Pazzaglia, Samantha Semenkow, Eli E Bar, Marcel Kool, Stefan Pfister, Heather M Bond, Charles G Eberhart, Christian SteinkÃ¼hler, Giovanni Morrone

Published Jul 27, 2013 · Vol. 4, No. 8 · pp. 1280-1292

Keywords: ZNF521, gene expression, medulloblastoma, cell growth, tumorigenicity, cancer stem cells

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Marc Delord, Philippe Rousselot, Jean-Michel Cayuela, FranÃ§ois Sigaux, JoÃ«lle Guilhot, Claude Preudhomme, FranÃ§ois Guilhot, Pascale Loiseau, Emmanuel Raffoux, Daniela Geromin, Emmanuelle Genin, Fabien Calvo, Heriberto Bruzzoni-Giovanelli

Published Jul 18, 2013 · Vol. 4, No. 10 · pp. 1582-1591

Keywords: CML, Imatinib, SNPs, ABCG2, Pharmacogenetic, molecular response, BCR-ABL

Combining TRAIL with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling Research Paper

Grazia Saturno, Melanie Valenti, Alexis De Haven Brandon, George V. Thomas, Suzanne Eccles, Paul A. Clarke, Paul Workman

Published Jul 14, 2013 · Vol. 4, No. 8 · pp. 1185-1198

Keywords: TRAIL, PI3 Kinase/mTOR, HSP90, apoptosis, colorectal cancer

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

Olga Ritz, Karolin Rommel, Karola Dorsch, Elena Kelsch, Julia Melzner, Michaela Buck, Karen Leroy, Vasiliki Papadopoulou, Simon Wagner, Jochen K Lennerz, Peter MÃ¶ller

Published Jul 13, 2013 · Vol. 4, No. 7 · pp. 1093-1102

Keywords: intratumoral heterogenity, PMBL, BCL6, pSTAT6

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Jennifer J. Wheler, David Hong, Stephen G. Swisher, Gerald S. Falchook, Apostolia Maria Tsimberidou, Thorunn Helgason, Aung Naing, Bettzy Stephen, Filip Janku, Philip J. Stephens, Roman Yelensky, Razelle Kurzrock

Published Jun 10, 2013 · Vol. 4, No. 6 · pp. 890-898

Keywords: advanced thymoma, mTOR inhibitors, targeted therapy, thymic carcinoma

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Reduced ING1 levels in breast cancer promotes metastasis Research Paper

Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma Research Paper

Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis Research Paper

The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors Research Paper

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways Priority Research Paper

miR-17 inhibition enhances the formation of kidney cancer spheres with stem cell/ tumor initiating cell properties Research Paper

Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another â€œdouble hitâ€ lymphoma with very poor outcome? Research Paper

The immunocytokine NHS-IL12 as a potential cancer therapeutic Research Paper

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines Research Paper

Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer Research Paper

Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Research Paper

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Combining TRAIL with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling Research Paper

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Reduced ING1 levels in breast cancer promotes metastasis Research Paper

Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma Research Paper

Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis Research Paper

The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors Research Paper

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways Priority Research Paper

miR-17 inhibition enhances the formation of kidney cancer spheres with stem cell/ tumor initiating cell properties Research Paper

Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another â€œdouble hitâ€ lymphoma with very poor outcome? Research Paper

The immunocytokine NHS-IL12 as a potential cancer therapeutic Research Paper

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines Research Paper

Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer Research Paper

Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Research Paper

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Combining TRAIL with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling Research Paper

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another â€œdouble hitâ€ lymphoma with very poor outcome? Research Paper