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Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy Clinical Research Papers

Rossana Berardi, Alessandro Brunelli, Silvia Pagliaretta, Vittorio Paolucci, Alessandro Conti, Gaia Goteri, Majed Refai, Cecilia Pompili, Giulia Marcantognini, Francesca Morgese, Zelmira Ballatore, Agnese Savini, Mariagrazia De Lisa, Miriam Caramanti, Matteo Santoni, Antonio Zizzi, Francesco Piva, Paola Mazzanti, Azzurra Onofri, Armando Sabbatini, Marina Scarpelli, Stefano Cascinu

Published Jun 8, 2015 · Vol. 6, No. 22 · pp. 19305-19315

Therapeutic efficacy of combined BRAF and MEK inhibition in metastatic melanoma: a comprehensive network meta-analysis of randomized controlled trials Clinical Research Papers

Ruiqin Mai, Songxia Zhou, Weixiang Zhong, Siming Rong, Zhichao Cong, Yunxian Li, Qizhi Xie, Huanming Chen, Xiaoyun Li, Shuhui Liu, Yabin Cheng, Yuanshen Huang, Youwen Zhou, Guohong Zhang

Published Jun 8, 2015 · Vol. 6, No. 29 · pp. 28502-28512

Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling Research Paper

Anja Heinemann, Carleen Cullinane, Ricardo De Paoli-Iseppi, James S. Wilmott, Dilini Gunatilake, Jason Madore, Dario Strbenac, Jean Y. Yang, Kavitha Gowrishankar, Jessamy C. Tiffen, Rab K. Prinjha, Nicholas Smithers, Grant A. McArthur, Peter Hersey, Stuart J. Gallagher

Published Jun 5, 2015 · Vol. 6, No. 25 · pp. 21507-21521

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia Research Paper

Jean-Emmanuel Bibault, Martin Figeac, Nathalie HÃ©levaut, CÃ©line Rodriguez, Sabine Quief, ShÃ©hÃ©razade Sebda, Aline Renneville, Olivier Nibourel, Philippe Rousselot, BÃ©rengÃ¨re Gruson, HervÃ© Dombret, Sylvie Castaigne, Claude Preudhomme

Published Jun 2, 2015 · Vol. 6, No. 26 · pp. 22812-22821

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

Michal Podrazil, Rudolf Horvath, Etienne Becht, Daniela Rozkova, Pavla Bilkova, Hana Hromadkova, Jana Kayserova, Katerina Vavrova, Jan Lastovicka, Petra Vrabcova, Katerina Kubackova, Zdenka Gasova, Ladislav Jarolim, Marek Babjuk, Radek Spisek, Jirina Bartunkova, Jitka Fucikova

Published May 29, 2015 · Vol. 6, No. 20 · pp. 18192-18205

Longitudinal study on circulating miRNAs in patients after lung cancer resection Clinical Research Papers

Petra Leidinger, Valentina Galata, Christina Backes, Cord StÃ¤hler, Stefanie Rheinheimer, Hanno Huwer, Eckart Meese, Andreas Keller

Published May 29, 2015 · Vol. 6, No. 18 · pp. 16674-16685

Functional intronic ERCC1 polymorphism from regulomeDB can predict survival in lung cancer after surgery Clinical Research Papers

Shin Yup Lee, Mi Jeong Hong, Hyo-Sung Jeon, Yi Young Choi, Jin Eun Choi, Hyo-Gyoung Kang, Deuk Kju Jung, Chengcheng Jin, Sook Kyung Do, Seung Soo Yoo, Yangki Seok, Eung Bae Lee, Kyung Min Shin, Ji Yun Jeong, Won Kee Lee, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Young Tae Kim, Sanghoon Jheon, Jae Yong Park

Published May 27, 2015 · Vol. 6, No. 27 · pp. 24522-24532

Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development Research Paper

Qingyang Gu, Bin Zhang, Hongye Sun, Qiang Xu, Yexiong Tan, Guan Wang, Qin Luo, Weiguo Xu, Shuqun Yang, Jian Li, Jing Fu, Lei Chen, Shengxian Yuan, Guibai Liang, Qunsheng Ji, Shu-Hui Chen, Chi-Chung Chan, Weiping Zhou, Xiaowei Xu, Hongyang Wang, Douglas D. Fang

Published May 21, 2015 · Vol. 6, No. 24 · pp. 20160-20176

Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy Research Paper

Oshrat Levi, Olga Genin, Corrado Angelini, Orna Halevy, Mark Pines

Published May 21, 2015 · Vol. 6, No. 27 · pp. 23249-23260

DNA methylation and cognitive aging Review

Xiangru Xu

Published May 20, 2015 · Vol. 6, No. 16 · pp. 13922-13932

Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma Research Paper

Matthew B. Siegel, Selina Qiuying Liu, Monika A. Davare, Stephen E. Spurgeon, Marc M. Loriaux, Brian J. Druker, Emma C. Scott, Jeffrey W. Tyner

Published May 20, 2015 · Vol. 6, No. 22 · pp. 18921-18932

Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: a randomized, open-label, prospective trial Clinical Research Papers

Jack P. Wang, Chen-Yi Wu, Yi-Cheng Yeh, Yi-Ming Shyr, Ying-Ying Wu, Chen-Yu Kuo, Yi-Ping Hung, Ming-Huang Chen, Wei-Ping Lee, Jiing-Chyuan Luo, Yee Chao, Chung-Pin Li

Published May 20, 2015 · Vol. 6, No. 20 · pp. 18162-18173

Virus-Clip: a fast and memory-efficient viral integration site detection tool at single-base resolution with annotation capability Research Paper

Daniel WH Ho, Karen MF Sze, Irene OL Ng

Published May 19, 2015 · Vol. 6, No. 25 · pp. 20959-20963

RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients Clinical Research Papers

Talia Golan, Elina Zorde Khvalevsky, Ayala Hubert, Rachel Malka Gabai, Naama Hen, Amiel Segal, Abraham Domb, Gil Harari, Eliel Ben David, Stephen Raskin, Yuri Goldes, Eran Goldin, Rami Eliakim, Maor Lahav, Yael Kopleman, Alain Dancour, Amotz Shemi, Eithan Galun

Published May 19, 2015 · Vol. 6, No. 27 · pp. 24560-24570

Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade Research Paper

Ijeoma Adaku Umelo, Olivier De Wever, Peter Kronenberger, Jan Van Deun, Alfiah Noor, Kshitiz Singh, Erik Teugels, Gang Chen, Marc Bracke, Jacques De GrÃ¨ve

Published May 15, 2015 · Vol. 6, No. 24 · pp. 20132-20144

A combination of YM-155, a small molecule survivin inhibitor, and IL-2 potently suppresses renal cell carcinoma in murine model Research Paper

Kai Guo, Peng Huang, Naijin Xu, Peng Xu, Haruki Kaku, Shaobo Zheng, Abai Xu, Eiji Matsuura, Chunxiao Liu, Hiromi Kumon

Published May 12, 2015 · Vol. 6, No. 25 · pp. 21137-21147

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells Research Paper

Marijke C.C. Sachweh, William C. Stafford, Catherine J. Drummond, Anna R. McCarthy, Maureen Higgins, Johanna Campbell, Bertha Brodin, Elias S.J. ArnÃ©r, Sonia LaÃn

Published May 12, 2015 · Vol. 6, No. 18 · pp. 16488-16506

Molecularâ€“genetic and clinical characteristics of gliomas with astrocytic appearance and total 1p19q loss in a single institutional consecutive cohort Research Paper

Saeko Hayashi, Hikaru Sasaki, Tokuhiro Kimura, Takayuki Abe, Takumi Nakamura, Yohei Kitamura, Tomoru Miwa, Kaori Kameyama, Yuichi Hirose, Kazunari Yoshida

Published May 11, 2015 · Vol. 6, No. 18 · pp. 15871-15881

YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network Research Paper

EloÃ¯se VÃ©quaud, CÃ©line SÃ©veno, Delphine Loussouarn, Lucie Engelhart, Mario Campone, Philippe Juin, Sophie BarillÃ©-Nion

Published May 6, 2015 · Vol. 6, No. 15 · pp. 13476-13486

Systemic attenuation of the TGF-Î² pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal Research Paper

Hanadie Yousef, Michael J. Conboy, Adam Morgenthaler, Christina Schlesinger, Lukasz Bugaj, Preeti Paliwal, Christopher Greer, Irina M. Conboy, David Schaffer

Published May 6, 2015 · Vol. 6, No. 14 · pp. 11959-11978

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Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy Clinical Research Papers

Therapeutic efficacy of combined BRAF and MEK inhibition in metastatic melanoma: a comprehensive network meta-analysis of randomized controlled trials Clinical Research Papers

Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling Research Paper

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia Research Paper

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

Longitudinal study on circulating miRNAs in patients after lung cancer resection Clinical Research Papers

Functional intronic ERCC1 polymorphism from regulomeDB can predict survival in lung cancer after surgery Clinical Research Papers

Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development Research Paper

Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy Research Paper

DNA methylation and cognitive aging Review

Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma Research Paper

Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: a randomized, open-label, prospective trial Clinical Research Papers

Virus-Clip: a fast and memory-efficient viral integration site detection tool at single-base resolution with annotation capability Research Paper

RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients Clinical Research Papers

Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade Research Paper

A combination of YM-155, a small molecule survivin inhibitor, and IL-2 potently suppresses renal cell carcinoma in murine model Research Paper

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells Research Paper

Molecularâ€“genetic and clinical characteristics of gliomas with astrocytic appearance and total 1p19q loss in a single institutional consecutive cohort Research Paper

YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network Research Paper

Systemic attenuation of the TGF-Î² pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy Clinical Research Papers

Therapeutic efficacy of combined BRAF and MEK inhibition in metastatic melanoma: a comprehensive network meta-analysis of randomized controlled trials Clinical Research Papers

Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling Research Paper

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia Research Paper

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

Longitudinal study on circulating miRNAs in patients after lung cancer resection Clinical Research Papers

Functional intronic ERCC1 polymorphism from regulomeDB can predict survival in lung cancer after surgery Clinical Research Papers

Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development Research Paper

Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy Research Paper

DNA methylation and cognitive aging Review

Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma Research Paper

Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: a randomized, open-label, prospective trial Clinical Research Papers

Virus-Clip: a fast and memory-efficient viral integration site detection tool at single-base resolution with annotation capability Research Paper

RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients Clinical Research Papers

Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade Research Paper

A combination of YM-155, a small molecule survivin inhibitor, and IL-2 potently suppresses renal cell carcinoma in murine model Research Paper

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells Research Paper

Molecularâ€“genetic and clinical characteristics of gliomas with astrocytic appearance and total 1p19q loss in a single institutional consecutive cohort Research Paper

YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network Research Paper

Systemic attenuation of the TGF-Î² pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal Research Paper