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Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Valentina Restelli, Rosaria ChilÃ, Monica Lupi, Andrea Rinaldi, Ivo Kwee, Francesco Bertoni, Giovanna Damia, Laura Carrassa

Published Oct 2, 2015 · Vol. 6, No. 35 · pp. 37229-37240

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts Research Paper

Christopher H. Lieu, Peter J. Klauck, Patrick K. Henthorn, John J. Tentler, Aik-Choon Tan, Anna Spreafico, Heather M. Selby, Blair C. Britt, Stacey M. Bagby, John J. Arcaroli, Wells A. Messersmith, Todd M. Pitts, S. Gail Eckhardt

Published Oct 1, 2015 · Vol. 6, No. 33 · pp. 34561-34572

Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design Research Paper

Andrew J. Massey, Stephen Stokes, Helen Browne, Nicolas Foloppe, AndreÃ¡ Fiumana, Simon Scrace, Mandy Fallowfield, Simon Bedford, Paul Webb, Lisa Baker, Mark Christie, Martin J. Drysdale, Mike Wood

Published Sep 30, 2015 · Vol. 6, No. 34 · pp. 35797-35812

Depletion of mucin in mucin-producing human gastrointestinal carcinoma: Results from in vitro and in vivo studies with bromelain and N-acetylcysteine Research Paper

Afshin Amini, Samar Masoumi-Moghaddam, Anahid Ehteda, Winston Liauw, David L Morris

Published Sep 30, 2015 · Vol. 6, No. 32 · pp. 33329-33344

Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma Research Paper

Chinthalapally V. Rao, Naveena B. Janakiram, Venkateshwar Madka, Vishal Devarkonda, Misty Brewer, Laura Biddick, Stan Lightfoot, Vernon E. Steele, Altaf Mohammed

Published Sep 28, 2015 · Vol. 6, No. 32 · pp. 33290-33305

Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases Research Paper

Valerio Leoni, Valentina Gatta, Arianna Palladini, Giordano Nicoletti, Dario Ranieri, Massimiliano Dallâ€™Ora, Valentina Grosso, Martina Rossi, Francesco Alviano, Laura Bonsi, Patrizia Nanni, Pier-Luigi Lollini, Gabriella Campadelli-Fiume

Published Sep 27, 2015 · Vol. 6, No. 33 · pp. 34774-34787

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes Research Paper

Kathy L. McGraw, Thomas Cluzeau, David A. Sallman, Ashley A. Basiorka, Brittany A. Irvine, Ling Zhang, P.K. Epling-Burnette, Dana E. Rollison, Mar Mallo, Lubomir Sokol, Francesc SolÃ©, Jaroslaw Maciejewski, Alan F. List

Published Sep 25, 2015 · Vol. 6, No. 33 · pp. 34437-34445

HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide Research Paper

Alessandro Canella, Hector Cordero Nieves, Douglas W. Sborov, Luciano Cascione, Hanna S. Radomska, Emily Smith, Andrew Stiff, Jessica Consiglio, Enrico Caserta, Lara Rizzotto, Nicola Zanesi, Volinia Stefano, Balveen Kaur, Xiaokui Mo, John C. Byrd, Yvonne A. Efebera, Craig C. Hofmeister, Flavia Pichiorri

Published Sep 25, 2015 · Vol. 6, No. 31 · pp. 31134-31150

Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction? Review

Reinaldo Franqui-Machin, Erik B. Wendlandt, Siegfried Janz, Fenghuang Zhan, Guido Tricot

Published Sep 22, 2015 · Vol. 6, No. 38 · pp. 40496-40506

Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats Research Paper

Sabzali Javadov, Sehwan Jang, Natividad Rodriguez-Reyes, Ana E. Rodriguez-Zayas, Jessica Soto Hernandez, Tanja Krainz, Peter Wipf, Walter Frontera

Published Sep 22, 2015 · Vol. 6, No. 37 · pp. 39469-39481

A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer Research Paper

Edward J. Richards, Jennifer Permuth-Wey, Yajuan Li, Y. Ann Chen, Domenico Coppola, Brett M. Reid, Hui-Yi Lin, Jamie K. Teer, Andrew Berchuck, Michael J. Birrer, Kate Lawrenson, Alvaro N.A. Monteiro, Joellen M. Schildkraut, Ellen L. Goode, Simon A. Gayther, Thomas A. Sellers, Jin Q. Cheng

Published Sep 22, 2015 · Vol. 6, No. 33 · pp. 34745-34757

Next generation sequencing in synovial sarcoma reveals novel gene mutations Research Paper

Myrella Vlenterie, Melissa H.S. Hillebrandt-Roeffen, Uta E. Flucke, Patricia J.T.A. Groenen, Bastiaan B.J. Tops, Eveline J. Kamping, Rolph Pfundt, Diederik R.H. de Bruijn, Ad H.M. Geurts van Kessel, Han J.H.J.M. van Krieken, Winette T.A. van der Graaf, Yvonne M.H. Versleijen-Jonkers

Published Sep 22, 2015 · Vol. 6, No. 33 · pp. 34680-34690

Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death Research Paper

Melissa Rosso, Alla Polotskaia, Jill Bargonetti

Published Sep 19, 2015 · Vol. 6, No. 33 · pp. 34573-34591

Validation of a rectal cancer outcome prediction model with a cohort of Chinese patients Clinical Research Papers

Lijun Shen, Johan van Soest, Jiazhou Wang, Jialu Yu, Weigang Hu, Yutao U. T. Gong, Vincenzo Valentini, Ying Xiao, Andre Dekker, Zhen Zhang

Published Sep 18, 2015 · Vol. 6, No. 35 · pp. 38327-38335

Age-related somatic mutations in the cancer genome Priority Research Paper

Brandon Milholland, Adam Auton, Yousin Suh, Jan Vijg

Published Sep 17, 2015 · Vol. 6, No. 28 · pp. 24627-24635

Imaging of carbonic anhydrase IX with an ¹¹¹In-labeled dual-motif inhibitor Research Paper

Xing Yang, Il Minn, Steven P. Rowe, Sangeeta Ray Banerjee, Michael A. Gorin, Mary Brummet, Hye Soo Lee, Soo Min Koo, Polina Sysa-Shah, Ronnie C. Mease, Sridhar Nimmagadda, Mohamad E. Allaf, Martin G. Pomper

Published Sep 16, 2015 · Vol. 6, No. 32 · pp. 33733-33742

Multibeam inverse intensity-modulated radiotherapy (IMRT) for whole breast irradiation: a single center experience in China Clinical Research Papers

Zhaozhi Yang, Li Zhang, Xingxing Chen, Jinli Ma, Xin Mei, Jiayi Chen, Xiaoli Yu, Xiaomao Guo

Published Sep 16, 2015 · Vol. 6, No. 33 · pp. 35063-35072

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Stefano Iacovelli, Maria Rosaria Ricciardi, Matteo Allegretti, Simone Mirabilii, Roberto Licchetta, Paola Bergamo, Cinzia Rinaldo, Ann Zeuner, Robin FoÃ, Michele Milella, James A. McCubrey, Alberto M. Martelli, Agostino Tafuri

Published Sep 16, 2015 · Vol. 6, No. 31 · pp. 32089-32103

Molecular inimitability amongst tumors: implications for precision cancer medicine in the age of personalized oncology Research Paper

Sandip Pravin Patel, Maria Schwaederle, Gregory A. Daniels, Paul T. Fanta, Richard B. Schwab, Kelly A. Shimabukuro, Santosh Kesari, David E. Piccioni, Lyudmila A. Bazhenova, Teresa L. Helsten, Scott M. Lippman, Barbara A. Parker, Razelle Kurzrock

Published Sep 16, 2015 · Vol. 6, No. 32 · pp. 32602-32609

HER2-specific immunoligands engaging NKp30 or NKp80 trigger NK-cell-mediated lysis of tumor cells and enhance antibody-dependent cell-mediated cytotoxicity Research Paper

Matthias Peipp, Stefanie Derer, Stefan Lohse, Matthias Staudinger, Katja Klausz, Thomas Valerius, Martin Gramatzki, Christian Kellner

Published Sep 15, 2015 · Vol. 6, No. 31 · pp. 32075-32088

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Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts Research Paper

Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design Research Paper

Depletion of mucin in mucin-producing human gastrointestinal carcinoma: Results from in vitro and in vivo studies with bromelain and N-acetylcysteine Research Paper

Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma Research Paper

Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases Research Paper

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes Research Paper

HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide Research Paper

Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction? Review

Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats Research Paper

A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer Research Paper

Next generation sequencing in synovial sarcoma reveals novel gene mutations Research Paper

Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death Research Paper

Validation of a rectal cancer outcome prediction model with a cohort of Chinese patients Clinical Research Papers

Age-related somatic mutations in the cancer genome Priority Research Paper

Imaging of carbonic anhydrase IX with an ¹¹¹In-labeled dual-motif inhibitor Research Paper

Multibeam inverse intensity-modulated radiotherapy (IMRT) for whole breast irradiation: a single center experience in China Clinical Research Papers

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Molecular inimitability amongst tumors: implications for precision cancer medicine in the age of personalized oncology Research Paper

HER2-specific immunoligands engaging NKp30 or NKp80 trigger NK-cell-mediated lysis of tumor cells and enhance antibody-dependent cell-mediated cytotoxicity Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts Research Paper

Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design Research Paper

Depletion of mucin in mucin-producing human gastrointestinal carcinoma: Results from in vitro and in vivo studies with bromelain and N-acetylcysteine Research Paper

Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma Research Paper

Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases Research Paper

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes Research Paper

HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide Research Paper

Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction? Review

Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats Research Paper

A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer Research Paper

Next generation sequencing in synovial sarcoma reveals novel gene mutations Research Paper

Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death Research Paper

Validation of a rectal cancer outcome prediction model with a cohort of Chinese patients Clinical Research Papers

Age-related somatic mutations in the cancer genome Priority Research Paper

Imaging of carbonic anhydrase IX with an 111In-labeled dual-motif inhibitor Research Paper

Multibeam inverse intensity-modulated radiotherapy (IMRT) for whole breast irradiation: a single center experience in China Clinical Research Papers

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Molecular inimitability amongst tumors: implications for precision cancer medicine in the age of personalized oncology Research Paper

HER2-specific immunoligands engaging NKp30 or NKp80 trigger NK-cell-mediated lysis of tumor cells and enhance antibody-dependent cell-mediated cytotoxicity Research Paper

Imaging of carbonic anhydrase IX with an ¹¹¹In-labeled dual-motif inhibitor Research Paper