The Oncosearch | Oncotarget

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

Claudia Pivonello, Mariarosaria Negri, Maria Cristina De Martino, Maria Napolitano, Cristina de Angelis, Donatella Paola Provvisiero, Gaia Cuomo, Renata Simona Auriemma, Chiara Simeoli, Francesco Izzo, Annamaria Colao, Leo J. Hofland, Rosario Pivonello

Published Jan 7, 2016 · Vol. 7, No. 9 · pp. 9718-9731

TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-Jun Research Paper

Ying Li, Zhiwei Yang, Weijie Li, Shudi Xu, Tao Wang, Ting Wang, Mengjie Niu, Shengli Zhang, Lintao Jia, Shengqing Li

Published Jan 6, 2016 · Vol. 7, No. 6 · pp. 6748-6764

HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress Research Paper

Ming-Da Wang, Han Wu, Shuai Huang, Hui-Lu Zhang, Chen-Jie Qin, Ling-Hao Zhao, Gong-Bo Fu, Xu Zhou, Xian-Ming Wang, Liang Tang, Wen Wen, We Yang, Shan-Hua Tang, Dan Cao, Lin-Na Guo, Min Zeng, Meng-Chao Wu, He-Xin Yan, Hong-Yang Wang

Published Jan 4, 2016 · Vol. 7, No. 6 · pp. 6711-6726

Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A Research Paper

Nadine Rohwer, Fabian Bindel, Christina Grimm, Suling J. Lin, Jessica Wappler, Bertram Klinger, Nils BlÃ¼thgen, Ilona Du Bois, Bernd Schmeck, Hans Lehrach, Marjo de Graauw, Emanuel Goncalves, Julio Saez-Rodriguez, Patrick Tan, Heike I. Grabsch, Alessandro Prigione, Stefan Kempa, Thorsten Cramer

Published Dec 29, 2015 · Vol. 7, No. 6 · pp. 6693-6710

Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells Research Paper

Elyse K. Hanly, Neha Y. Tuli, Robert B. Bednarczyk, Robert Suriano, Jan Geliebter, Augustine L. Moscatello, Zbigniew Darzynkiewicz, Raj K. Tiwari

Published Dec 28, 2015 · Vol. 7, No. 8 · pp. 8676-8687

Combating autophagy is a strategy to increase cytotoxic effects of novel ALK inhibitor entrectinib in neuroblastoma cells Research Paper

Sanja Aveic, Marcella Pantile, Anke Seydel, Maria Rosaria Esposito, Carlo Zanon, Gary Li, Gian Paolo Tonini

Published Dec 28, 2015 · Vol. 7, No. 5 · pp. 5646-5663

Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer Research Paper

Shu-Heng Jiang, Yang Wang, Jian-Yu Yang, Jun Li, Ming-Xuan Feng, Ya-Hui Wang, Xiao-Mei Yang, Ping He, Guang-Ang Tian, Xiao-Xin Zhang, Qing Li, Xiao-Yan Cao, Yan-Miao Huo, Min-Wei Yang, Xue-Liang Fu, Jiao Li, De-Jun Liu, Miao Dai, Shan-Yun Wen, Jian-Ren Gu, Jie Hong, Rong Hua, Zhi-Gang Zhang, Yong-Wei Sun

Published Dec 28, 2015 · Vol. 7, No. 4 · pp. 4226-4240

HER-3 targeting alters the dimerization pattern of ErbB protein family members in breast carcinomas Research Paper

Michalis V. Karamouzis, Georgia Dalagiorgou, Urania Georgopoulou, Afroditi Nonni, Michalis Kontos, Athanasios G. Papavassiliou

Published Dec 26, 2015 · Vol. 7, No. 5 · pp. 5576-5597

Combination therapy of RY10-4 with the Î³-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer Research Paper

Feng Su, Shilin Zhu, Jinlan Ruan, Yagmur Muftuoglu, Longbo Zhang, Qianying Yuan

Published Dec 26, 2015 · Vol. 7, No. 4 · pp. 4142-4154

Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer Research Paper

Naoki Takahashi, Koh Furuta, Hirokazu Taniguchi, Yusuke Sasaki, Hirokazu Shoji, Yoshitaka Honma, Satoru Iwasa, Natsuko Okita, Atsuo Takashima, Ken Kato, Tetsuya Hamaguchi, Yasuhiro Shimada, Yasuhide Yamada

Published Dec 24, 2015 · Vol. 7, No. 4 · pp. 4925-4938

High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells Research Paper

Shigeki Nanjo, Hiromichi Ebi, Sachiko Arai, Shinji Takeuchi, Tadaaki Yamada, Satsuki Mochizuki, Yasunori Okada, Mitsutoshi Nakada, Takashi Murakami, Seiji Yano

Published Dec 24, 2015 · Vol. 7, No. 4 · pp. 3847-3856

FZD7 regulates BMSCs-mediated protection of CML cells Research Paper

Na Liu, Shaolei Zang, Yan Liu, Yingqiao Wang, Wei Li, Qiang Liu, Min Ji, Daoxin Ma, Chunyan Ji

Published Dec 23, 2015 · Vol. 7, No. 5 · pp. 6175-6187

Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells Research Paper

Haiying Cheng, Zhenfeng Zhang, Ruth Rodriguez-Barrueco, Alain Borczuk, Huijie Liu, Jiyang Yu, Jose M. Silva, Simon K. Cheng, Roman Perez-Soler, Balazs Halmos

Published Dec 22, 2015 · Vol. 7, No. 20 · pp. 28976-28988

miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG Research Paper

Longtao Huangfu, Haihai Liang, Guojie Wang, Xiaomin Su, Linqiang Li, Zhimin Du, Meiyu Hu, Yuechao Dong, Xue Bai, Tianyi Liu, Baofeng Yang, Hongli Shan

Published Dec 22, 2015 · Vol. 7, No. 4 · pp. 4735-4745

Targeting Notch to overcome radiation resistance Review

Sanaz Yahyanejad, Jan Theys, Marc Vooijs

Published Dec 21, 2015 · Vol. 7, No. 7 · pp. 7610-7628

Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma Research Paper

Pi-Lin Sung, Yi-Hua Jan, Shih-Chieh Lin, Chao-Cheng Huang, Hao Lin, Kuo-Chang Wen, Kuan-Chong Chao, Chiung-Ru Lai, Peng-Hui Wang, Chi-Mu Chuang, Hua-Hsi Wu, Nae-Fang Twu, Ming-Shyen Yen, Michael Hsiao, Chi-Ying F. Huang

Published Dec 21, 2015 · Vol. 7, No. 4 · pp. 4036-4047

p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy Research Paper

Brigitte Bisaro, Marianna Sciortino, Shana Colombo, Maria Pilar Camacho Leal, Andrea Costamagna, Isabella Castellano, Filippo Montemurro, Valentina Rossi, Giorgio Valabrega, Emilia Turco, Paola Defilippi, Sara Cabodi

Published Dec 21, 2015 · Vol. 7, No. 4 · pp. 4442-4453

Tea nanoparticle, a safe and biocompatible nanocarrier, greatly potentiates the anticancer activity of doxorubicin Research Paper

Yi-Jun Wang, Yujian Huang, Nagaraju Anreddy, Guan-Nan Zhang, Yun-Kai Zhang, Meina Xie, Derrick Lin, Dong-Hua Yang, Mingjun Zhang, Zhe-Sheng Chen

Published Dec 21, 2015 · Vol. 7, No. 5 · pp. 5877-5891

The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma Research Paper

David Y.A. Dadey, Vaishali Kapoor, Arpine Khudanyan, Fumihiko Urano, Albert H. Kim, Dinesh Thotala, Dennis E. Hallahan

Published Dec 21, 2015 · Vol. 7, No. 2 · pp. 2080-2092

Novel strategies to target the ubiquitin proteasome system in multiple myeloma Review

Susanne Lub, Ken Maes, Eline Menu, Elke De Bruyne, Karin Vanderkerken, Els Van Valckenborgh

Published Dec 18, 2015 · Vol. 7, No. 6 · pp. 6521-6537

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The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-Jun Research Paper

HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress Research Paper

Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A Research Paper

Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells Research Paper

Combating autophagy is a strategy to increase cytotoxic effects of novel ALK inhibitor entrectinib in neuroblastoma cells Research Paper

Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer Research Paper

HER-3 targeting alters the dimerization pattern of ErbB protein family members in breast carcinomas Research Paper

Combination therapy of RY10-4 with the Î³-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer Research Paper

Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer Research Paper

High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells Research Paper

FZD7 regulates BMSCs-mediated protection of CML cells Research Paper

Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells Research Paper

miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG Research Paper

Targeting Notch to overcome radiation resistance Review

Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma Research Paper

p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy Research Paper

Tea nanoparticle, a safe and biocompatible nanocarrier, greatly potentiates the anticancer activity of doxorubicin Research Paper

The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma Research Paper

Novel strategies to target the ubiquitin proteasome system in multiple myeloma Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-Jun Research Paper

HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress Research Paper

Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A Research Paper

Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells Research Paper

Combating autophagy is a strategy to increase cytotoxic effects of novel ALK inhibitor entrectinib in neuroblastoma cells Research Paper

Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer Research Paper

HER-3 targeting alters the dimerization pattern of ErbB protein family members in breast carcinomas Research Paper

Combination therapy of RY10-4 with the Î³-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer Research Paper

Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer Research Paper

High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells Research Paper

FZD7 regulates BMSCs-mediated protection of CML cells Research Paper

Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells Research Paper

miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG Research Paper

Targeting Notch to overcome radiation resistance Review

Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma Research Paper

p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy Research Paper

Tea nanoparticle, a safe and biocompatible nanocarrier, greatly potentiates the anticancer activity of doxorubicin Research Paper

The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma Research Paper

Novel strategies to target the ubiquitin proteasome system in multiple myeloma Review