The Oncosearch | Oncotarget

Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment Research Paper

Elham Hosseini-Beheshti, Wendy Choi, Louis-Bastien Weiswald, Geetanjali Kharmate, Mazyar Ghaffari, Mani Roshan-Moniri, Mohamed D. Hassona, Leslie Chan, Mei Yieng Chin, Isabella T. Tai, Paul S. Rennie, Ladan Fazli, Emma S. Tomlinson Guns

Published Jan 28, 2016 · Vol. 7, No. 12 · pp. 14639-14658

JNK pathway inhibition selectively primes pancreatic cancer stem cells to TRAIL-induced apoptosis without affecting the physiology of normal tissue resident stem cells Research Paper

Alejandro Recio-Boiles, Matthias Ilmer, P. Robyn Rhea, Claudia Kettlun, Mitja L. Heinemann, Jennifer Ruetering, Jody Vykoukal, Eckhard Alt

Published Jan 28, 2016 · Vol. 7, No. 9 · pp. 9890-9906

Mechanisms of resistance and sensitivity to anti-HER2 therapies in HER2+ breast cancer Review

Debora de Melo Gagliato, Denis Leonardo Fontes Jardim, Mario Sergio Pereira Marchesi, Gabriel N. Hortobagyi

Published Jan 27, 2016 · Vol. 7, No. 39 · pp. 64431-64446

Differential regulation of mTOR signaling determines sensitivity to AKT inhibition in diffuse large B cell lymphoma Research Paper

Scott A. Ezell, Suping Wang, Teeru Bihani, Zhongwu Lai, Shaun E. Grosskurth, Suprawee Tepsuporn, Barry R. Davies, Dennis Huszar, Kate F. Byth

Published Jan 27, 2016 · Vol. 7, No. 8 · pp. 9163-9174

Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1 Research Paper

Dimitri Topalis, Tatiane C. Nogueira, Tim De Schutter, Chahrazade El Amri, Marcela KreÄmerovÃ¡, Lieve Naesens, Jan Balzarini, Graciela Andrei, Robert Snoeck

Published Jan 25, 2016 · Vol. 7, No. 9 · pp. 10386-10401

Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway Research Paper

Yiying Wang, Yue Wang, Zhenbo Zhang, Ji-Young Park, Donghui Guo, Hong Liao, Xiaofang Yi, Yu Zheng, Donna Zhang, Setsuko K. Chambers, Wenxin Zheng

Published Jan 25, 2016 · Vol. 7, No. 9 · pp. 10363-10372

A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function Research Paper

Gang Chen, Junhua Liu, Wantao Chen, Qin Xu, Meng Xiao, Lihong Hu, Li Mao, Xu Wang

Published Jan 25, 2016 · Vol. 7, No. 8 · pp. 9388-9403

Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations Research Paper

Yi Sun, Wei Zhang, Yunqin Chen, Qin Ma, Jia Wei, Qi Liu

Published Jan 25, 2016 · Vol. 7, No. 8 · pp. 9404-9419

MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes Research Paper

Aroa Soriano, Laia ParÃs-Coderch, Luz Jubierre, Alba MartÃnez, Xiangyu Zhou, Olga Piskareva, Isabella Bray, Isaac Vidal, Ana AlmazÃ¡n-Moga, Carla Molist, Josep Roma, JosÃ© R. Bayascas, Oriol Casanovas, Raymond L. Stallings, JosÃ© SÃ¡nchez de Toledo, Soledad Gallego, Miguel F. Segura

Published Jan 25, 2016 · Vol. 7, No. 8 · pp. 9271-9287

Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer? Research Paper

Valentin DerangÃ¨re, Jean David Fumet, Romain Boidot, Leila Bengrine, Emeric Limagne, AngÃ©lique Chevriaux, Julie Vincent, Sylvain Ladoire, Lionel Apetoh, CÃ©dric RÃ©bÃ©, FranÃ§ois Ghiringhelli

Published Jan 25, 2016 · Vol. 7, No. 8 · pp. 9309-9321

Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers Research Paper

Sariah Liu, Mina Nikanjam, Razelle Kurzrock

Published Jan 25, 2016 · Vol. 7, No. 10 · pp. 11310-11320

Tumor resistance to vascular disrupting agents: mechanisms, imaging, and solutions Review

Wenjie Liang, Yicheng Ni, Feng Chen

Published Jan 24, 2016 · Vol. 7, No. 13 · pp. 15444-15459

CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression Research Paper

Partha Mitra, Ren-Ming Yang, James Sutton, Robert G. Ramsay, Thomas J. Gonda

Published Jan 24, 2016 · Vol. 7, No. 8 · pp. 9069-9083

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Milica Stefanovic, Anna Tutusaus, Guillermo A. Martinez-Nieto, Cristina BÃ¡rcena, Estefania de Gregorio, Catia Moutinho, Elisabet Barbero-Camps, Alberto Villanueva, Anna Colell, Montserrat MarÃ, Carmen GarcÃa-Ruiz, Jose C. Fernandez-Checa, Albert Morales

Published Jan 22, 2016 · Vol. 7, No. 7 · pp. 8253-8267

Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers Research Paper

Betty Yuen Kwan Law, Simon Wing Fai Mok, Wai Kit Chan, Su Wei Xu, An Guo Wu, Xiao Jun Yao, Jing Rong Wang, Liang Liu, Vincent Kam Wai Wong

Published Jan 22, 2016 · Vol. 7, No. 7 · pp. 8090-8104

PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells Research Paper

Winson S. Ho, Michael J. Feldman, Dragan Maric, Lauren Amable, Matthew D. Hall, Gerald M. Feldman, Abhik Ray-Chaudhury, Martin J. Lizak, Juan-Carlos Vera, R. Aaron Robison, Zhengping Zhuang, John D. Heiss

Published Jan 21, 2016 · Vol. 7, No. 11 · pp. 12447-12463

Blocking the survival of the nastiest by HSP90 inhibition Research Perspective

Paul Workman, Paul A. Clarke, Bissan Al-Lazikani

Published Jan 21, 2016 · Vol. 7, No. 4 · pp. 3658-3661

Deletions of multidrug resistance gene loci in breast cancer leads to the down-regulation of its expression and predict tumor response to neoadjuvant chemotherapy Research Paper

Nikolai V. Litviakov, Nadezhda V. Cherdyntseva, Matvey M. Tsyganov, Ð•lena Ðœ. Slonimskaya, Marina K. Ibragimova, Polina V. Kazantseva, Julia Kzhyshkowska, Eugeniy L. Choinzonov

Published Jan 20, 2016 · Vol. 7, No. 7 · pp. 7829-7841

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA Research Paper

Marzia Del Re, Marcello Tiseo, Paola Bordi, Armida Dâ€™Incecco, Andrea Camerini, Iacopo Petrini, Maurizio Lucchesi, Alessandro Inno, Daniele Spada, Enrico Vasile, Valentina Citi, Giorgio Malpeli, Enrica Testa, Stefania Gori, Alfredo Falcone, Domenico Amoroso, Antonio Chella, Federico Cappuzzo, Andrea Ardizzoni, Aldo Scarpa, Romano Danesi

Published Jan 20, 2016 · Vol. 8, No. 8 · pp. 13611-13619

miR-493 mediated DKK1 down-regulation confers proliferation, invasion and chemo-resistance in gastric cancer cells Research Paper

Xiaoting Jia, Nan Li, Cong Peng, Yingen Deng, Jia Wang, Min Deng, Minying Lu, Jiang Yin, Guopei Zheng, Haiying Liu, Zhimin He

Published Jan 20, 2016 · Vol. 7, No. 6 · pp. 7044-7054

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Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment Research Paper

JNK pathway inhibition selectively primes pancreatic cancer stem cells to TRAIL-induced apoptosis without affecting the physiology of normal tissue resident stem cells Research Paper

Mechanisms of resistance and sensitivity to anti-HER2 therapies in HER2+ breast cancer Review

Differential regulation of mTOR signaling determines sensitivity to AKT inhibition in diffuse large B cell lymphoma Research Paper

Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1 Research Paper

Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway Research Paper

A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function Research Paper

Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations Research Paper

MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes Research Paper

Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer? Research Paper

Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers Research Paper

Tumor resistance to vascular disrupting agents: mechanisms, imaging, and solutions Review

CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression Research Paper

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers Research Paper

PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells Research Paper

Blocking the survival of the nastiest by HSP90 inhibition Research Perspective

Deletions of multidrug resistance gene loci in breast cancer leads to the down-regulation of its expression and predict tumor response to neoadjuvant chemotherapy Research Paper

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA Research Paper

miR-493 mediated DKK1 down-regulation confers proliferation, invasion and chemo-resistance in gastric cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment Research Paper

JNK pathway inhibition selectively primes pancreatic cancer stem cells to TRAIL-induced apoptosis without affecting the physiology of normal tissue resident stem cells Research Paper

Mechanisms of resistance and sensitivity to anti-HER2 therapies in HER2+ breast cancer Review

Differential regulation of mTOR signaling determines sensitivity to AKT inhibition in diffuse large B cell lymphoma Research Paper

Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1 Research Paper

Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway Research Paper

A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function Research Paper

Identifying anti-cancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell line-based drug perturbations Research Paper

MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes Research Paper

Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer? Research Paper

Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers Research Paper

Tumor resistance to vascular disrupting agents: mechanisms, imaging, and solutions Review

CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression Research Paper

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers Research Paper

PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells Research Paper

Blocking the survival of the nastiest by HSP90 inhibition Research Perspective

Deletions of multidrug resistance gene loci in breast cancer leads to the down-regulation of its expression and predict tumor response to neoadjuvant chemotherapy Research Paper

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA Research Paper

miR-493 mediated DKK1 down-regulation confers proliferation, invasion and chemo-resistance in gastric cancer cells Research Paper