The Oncosearch | Oncotarget

Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1 Research Paper

Erik L. Brincks, James Adams, Lifu Wang, Benjamin Turner, Agnieszka Marcinowicz, Jiyuan Ke, Michael Essmann, Lucía M. Mautino, Clarissa Van Allen, Sanjeev Kumar, Nicholas Vahanian, Charles Link, Mario R. Mautino

Published Jun 9, 2020 · Vol. 11, No. 25 · pp. 2438-2461

Keywords: indoximod, IDO, TDO, AhR, mTORC1

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Rive Sarfstein, Haim Werner

Published Jun 9, 2020 · Vol. 11, No. 25 · pp. 2424-2437

Keywords: insulin, insulin-like growth factor-1 (IGF1), insulin receptor, IGF1 receptor, p53

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Joshua T. Rose, Eliana Moskovitz, Joseph R. Boyd, Jonathan A. Gordon, Nicole A. Bouffard, Andrew J. Fritz, Anuradha Illendula, John H. Bushweller, Jane B. Lian, Janet L. Stein, Sayyed K. Zaidi, Gary S. Stein

Published May 30, 2020 · Vol. 11, No. 26 · pp. 2512-2530

Keywords: mammary epithelial phenotype, epithelial phenotype, RUNX1, CBFβ, mitotic gene bookmarking

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

Sumit Bhattacharyya, Leo Feferman, Xiaorui Han, Ke Xia, Fuming Zhang, Robert J. Linhardt, Joanne K. Tobacman

Published May 28, 2020 · Vol. 11, No. 24 · pp. 2327-2344

Keywords: sulfotransferase, sulfatase, chondroitin sulfate, Wnt, EMT

Preliminary safety and imaging efficacy of the near-infrared fluorescent contrast agent DA364 during fluorescence-guided surgery in dogs with spontaneous superficial tumors Research Paper

Sophie Favril, Chiara Brioschi, Katrien Vanderperren, Eline Abma, Emmelie Stock, Nausikaa Devriendt, Ingeborgh Polis, Hilde De Cock, Alessia Cordaro, Luigi Miragoli, Paolo Oliva, Giovanni Valbusa, Charline Alleaume, Isabelle Tardy, Alessandro Maiocchi, Fabio Tedoldi, Francesco Blasi, Hilde de Rooster

Published May 28, 2020 · Vol. 11, No. 24 · pp. 2310-2326

Keywords: fluorescence-guided surgery, fluorescent contrast agent, near-infrared fluorescence imaging, spontaneous tumors, canine

BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer Research Paper

Mai Ahmed Shafei, Thomas Forshaw, Jasmine Davis, Arwa Flemban, David Qualtrough, Sarah Dean, Claire Perks, Ming Dong, Robert Newman, Myra Elizabeth Conway

Published May 8, 2020 · Vol. 11, No. 21 · pp. 1971-1987

Keywords: BCAT, PI3K-AKT, ERK, breast cancer

Efficacy of osimertinib against EGFRvIII+ glioblastoma Research Paper

Gustavo Chagoya, Shawn G. Kwatra, Cory W. Nanni, Callie M. Roberts, Samantha M. Phillips, Sarah Nullmeyergh, Samuel P. Gilmore, Ivan Spasojevic, David L. Corcoran, Christopher C. Young, Karla V. Ballman, Rohan Ramakrishna, Darren A. Cross, James M. Markert, Michael Lim, Mark R. Gilbert, Glenn J. Lesser, Madan M. Kwatra

Published May 5, 2020 · Vol. 11, No. 22 · pp. 2074-2082

Keywords: EGFRvIII, tyrosine kinase, glioblastoma stem cells, osimertinib, xenografts

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Anke Vermehren-Schmaedick, Paulette Mhawech-Fauceglia, Byung S. Park, Tanja Pejovic, Shiuh-Wen Luoh

Published May 1, 2020 · Vol. 11, No. 24 · pp. 2273-2289

Keywords: GRB7 expression, breast cancer, ovarian cancer, immunohistochemistry, prognosis

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Cindy K. Miranti, Sara Moore, Yongeun Kim, Venkateshwar Reddy Chappeta, Kui Wu, Biswanath De, Vijay Gokhale, Laurence H. Hurley, Elsa M. Reyes-Reyes

Published Apr 26, 2020 · Vol. 11, No. 19 · pp. 1758-1776

Keywords: prostate cancer, androgen receptor, nucleolin, gene repression, G-quadruplex

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Carmen J. Narvaez, Erika LaPorta, Samantha Robilotto, Jennifer Liang, JoEllen Welsh

Published Apr 25, 2020 · Vol. 11, No. 30 · pp. 2889-2905

Keywords: vitamin D, hyaluronic acid, hyaluronan synthase, HAS2, breast cancer

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

Suparna Mazumder, Valerie Swank, Anton A. Komar, Justin M. Johnson, Vincent K. Tuohy

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1894-1910

Keywords: monoclonal antibody, anti-Müllerian hormone receptor type II, immunotherapy, ovarian cancer, 4D12G1

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Diana Barea Roldán, Matthias Grimmler, Christoph Hartmann, Stefanie Hubich-Rau, Tim Beißert, Claudia Paret, Giuseppe Cagna, Christoph Rohde, Stefan Wöll, Michael Koslowski, Özlem Türeci, Ugur Sahin

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1862-1875

Keywords: PLAC1, tumorigenesis, extracellular matrix, fibroblast growth factor, AKT

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Thao Pham, Kristin Robinson, Terra Vleeshouwer-Neumann, James E. Annis, Eleanor Y. Chen

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1448-1461

Keywords: rhabdomyosarcoma, self-renewal, GRK5, kinase, cell cycle

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Inês Gomes, Bernardo P. de Almeida, Sara Dâmaso, André Mansinho, Inês Correia, Sara Henriques, Raquel Cruz-Duarte, Guilherme Vilhais, Pedro Félix, Patrícia Alves, Patrícia Corredeira, Nuno L. Barbosa-Morais, Luis Costa, Sandra Casimiro

Published Apr 18, 2020 · Vol. 11, No. 19 · pp. 1714-1728

Keywords: RANKL-RANK pathway, ER+ breast cancer, resistance to chemo and hormone therapy, stemness, metastization

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Wen Luo, Changxin Xu, Sarah Phillips, Aliza Gardenswartz, Jeremy M. Rosenblum, Janet Ayello, Stephen L. Lessnick, Huai-Xiang Hao, Mitchell S. Cairo

Published Apr 16, 2020 · Vol. 11, No. 19 · pp. 1691-1704

Keywords: PPP1R1A, cell cycle control, IGF-1R, metastasis, Ewing sarcoma

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

Andy Karabajakian, Thibaut Garrivier, Carole Crozes, Nicolas Gadot, Jean-Yves Blay, Frédéric Bérard, Philippe Céruse, Philippe Zrounba, Pierre Saintigny, Charles Mastier, Jérôme Fayette

Published Apr 11, 2020 · Vol. 11, No. 18 · pp. 1618-1628

Keywords: squamous cell carcinoma of head and neck, immunotherapy, programmed cell death 1 receptor, kinetics

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Matthew H. Taylor, Ajjai S. Alva, Timothy Larson, Sebastian Szpakowski, Das Purkaystha, Alpesh Amin, Linda Karpiak, Sarina A. Piha-Paul

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1235-1243

Keywords: advanced malignancies, basket trial, dovitinib, histology-agnostic, mutation-specific

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Natalia V. Eremina, Vasily I. Kazey, Sergey V. Mishugin, Roman V. Leonenkov, Dmitry Y. Pushkar, Vadim L. Mett, Andrei V. Gudkov

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1273-1288

Keywords: prostate cancer, immunotherapy, mobilan, adenoviral vector, intratumor injection

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Xi Xiao, Carsten Sticht, Libo Yin, Li Liu, Svetlana Karakhanova, Yefeng Yin, Christina Georgikou, Jury Gladkich, Wolfgang Gross, Norbert Gretz, Ingrid Herr

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1203-1217

Keywords: broccoli, broccoletti, Brassica rapa sylvestris, plant microRNAs, cross-kingdom regulation

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Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1 Research Paper

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

Preliminary safety and imaging efficacy of the near-infrared fluorescent contrast agent DA364 during fluorescence-guided surgery in dogs with spontaneous superficial tumors Research Paper

BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer Research Paper

Efficacy of osimertinib against EGFRvIII+ glioblastoma Research Paper

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1 Research Paper

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

Preliminary safety and imaging efficacy of the near-infrared fluorescent contrast agent DA364 during fluorescence-guided surgery in dogs with spontaneous superficial tumors Research Paper

BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer Research Paper

Efficacy of osimertinib against EGFRvIII+ glioblastoma Research Paper

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer Research Paper

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper