The Oncosearch | Oncotarget

Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells Research Paper

Ahmed Abdelbaset-Ismail, Sylwia Borkowska, Anna Janowska-Wieczorek, Torsten Tonn, Cesar Rodriguez, Marcin Moniuszko, Lukasz Bolkun, Janusz Koloczko, Andrzej Eljaszewicz, Janina Ratajczak, Mariusz Z. Ratajczak, Magda Kucia

Published Dec 20, 2015 · Vol. 7, No. 3 · pp. 3033-3046

Interferon-Î³-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation Research Paper

Fuad Bahram, Per Hydbring, Susanna TronnersjÃ¶, Siti Mariam Zakaria, Oliver Frings, Sara FahlÃ©n, HelÃ©n Nilsson, Jacob Goodwin, Natalie von der Lehr, Yingtao Su, Bernhard LÃ¼scher, Alina Castell, Lars-Gunnar Larsson

Published Dec 20, 2015 · Vol. 7, No. 3 · pp. 2837-2854

VE-cadherin cleavage by ovarian cancer microparticles induces Î²-catenin phosphorylation in endothelial cells Research Paper

Hamda Al Thawadi, Nadine Abu-Kaoud, Haleema Al Farsi, Jessica Hoarau-VÃ©chot, Shahin Rafii, Arash Rafii, Jennifer Pasquier

Published Dec 19, 2015 · Vol. 7, No. 5 · pp. 5289-5305

ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells Research Paper

Ka Bian, Naveen Reddy Muppani, Lobna Elkhadragy, Wei Wang, Cheng Zhang, Tenghui Chen, Sungyun Jung, Ole Morten Seternes, Weiwen Long

Published Dec 19, 2015 · Vol. 7, No. 6 · pp. 6665-6675

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling Research Paper

Erna Raja, Kalliopi Tzavlaki, Robin Vuilleumier, Karolina Edlund, Kaoru Kahata, Agata Zieba, Anita MorÃ©n, Yukihide Watanabe, Iryna Voytyuk, Johan Botling, Ola SÃ¶derberg, Patrick Micke, George Pyrowolakis, Carl-Henrik Heldin, Aristidis Moustakas

Published Dec 19, 2015 · Vol. 7, No. 2 · pp. 1120-1143

Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma Research Paper

Shuqun Yang, Chonglin Luo, Qingyang Gu, Qiang Xu, Guan Wang, Hongye Sun, Ziliang Qian, Yexiong Tan, Yuxin Qin, Yuhong Shen, Xiaowei Xu, Shu-Hui Chen, Chi-Chung Chan, Hongyang Wang, Mao Mao, Douglas D. Fang

Published Dec 19, 2015 · Vol. 7, No. 5 · pp. 5461-5469

Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway Research Paper

Fengtao Su, Souparno Bhattacharya, Salim Abdisalaam, Shibani Mukherjee, Hirohiko Yajima, Yanyong Yang, Ritu Mishra, Kalayarasan Srinivasan, Subroto Ghose, David J. Chen, Steven M. Yannone, Aroumougame Asaithamby

Published Dec 18, 2015 · Vol. 7, No. 1 · pp. 46-65

Activated T cells sustain myeloid-derived suppressor cell-mediated immune suppression Research Paper

Laura Pinton, Samantha Solito, Vera Damuzzo, Samuela Francescato, Assunta Pozzuoli, Antonio Berizzi, Simone Mocellin, Carlo Riccardo Rossi, Vincenzo Bronte, Susanna Mandruzzato

Published Dec 18, 2015 · Vol. 7, No. 2 · pp. 1168-1184

A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer Research Paper

David Paladino, Peibin Yue, Hideki Furuya, Jared Acoba, Charles J. Rosser, James Turkson

Published Dec 17, 2015 · Vol. 7, No. 6 · pp. 7253-7267

PKCÎ´ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling Research Paper

Eunji Hwang, Ki-Chun Yoo, Seok-Gu Kang, Rae-Kwon Kim, Yan-Hong Cui, Hae-June Lee, Min-Jung Kim, Jae-Seong Lee, In-Gyu Kim, Yongjoon Suh, Su-Jae Lee

Published Dec 17, 2015 · Vol. 7, No. 4 · pp. 4890-4902

Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells Research Paper

VÃctor GarcÃa, Maribel Lara-Chica, Irene Cantarero, Olov Sterner, Marco A. Calzado, Eduardo MuÃ±oz

Published Dec 14, 2015 · Vol. 7, No. 4 · pp. 4490-4506

The B56Î³3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1 Research Paper

Tai-Yu Lai, Chia-Jui Yen, Hung-Wen Tsai, Yu-San Yang, Wei-Fu Hong, Chi-Wu Chiang

Published Dec 14, 2015 · Vol. 7, No. 4 · pp. 4542-4558

Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome Research Paper

Yujiao He, Junmei Huang, Ping Wang, Xiaofei Shen, Sheng Li, Lijuan Yang, Wanli Liu, Apichart Suksamrarn, Guolin Zhang, Fei Wang

Published Dec 14, 2015 · Vol. 7, No. 4 · pp. 4664-4679

Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells Research Paper

Carminia Maria Della Corte, Vincenza Ciaramella, Concetta Di Mauro, Maria Domenica Castellone, Federica Papaccio, Morena Fasano, Ferdinando Carlo Sasso, Erika Martinelli, Teresa Troiani, Ferdinando De Vita, Michele Orditura, Roberto Bianco, Fortunato Ciardiello, Floriana Morgillo

Published Dec 11, 2015 · Vol. 7, No. 4 · pp. 4265-4278

UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation Research Paper

Cheng Du, Hong Wu, Roger P. Leng

Published Dec 10, 2015 · Vol. 7, No. 3 · pp. 2823-2836

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

Parag P. Patwardhan, Kathryn S. Ivy, Elgilda Musi, Elisa de Stanchina, Gary K. Schwartz

Published Dec 10, 2015 · Vol. 7, No. 4 · pp. 4093-4109

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway Research Paper

Ning Tang, Lei Shi, Zhenlong Yu, Peipei Dong, Chao Wang, Xiaokui Huo, Baojing Zhang, Shanshan Huang, Sa Deng, Kexin Liu, Tonghui Ma, Xiaobo Wang, Lijun Wu, Xiaochi Ma

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3533-3547

MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth Research Paper

Roberta Colladel, Rosanna Pellicani, Eva Andreuzzi, Alice Paulitti, Giulia Tarticchio, Federico Todaro, Alfonso Colombatti, Maurizio Mongiat

Published Dec 9, 2015 · Vol. 7, No. 2 · pp. 2022-2037

Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells Research Paper

Hongyu Li, Jing Hu, Shuhong Wu, Li Wang, Xiaobo Cao, Xiaoshan Zhang, Bingbing Dai, Mengru Cao, Ruping Shao, Ran Zhang, Mourad Majidi, Lin Ji, John V. Heymach, Michael Wang, Shiyang Pan, John Minna, Reza J. Mehran, Stephen G. Swisher, Jack A. Roth, Bingliang Fang

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3548-3558

IL-27 induces the expression of IDO and PD-L1 in human cancer cells Research Paper

Grazia Carbotti, Gaia Barisione, Irma Airoldi, Delia Mezzanzanica, Marina Bagnoli, Simone Ferrero, Andrea Petretto, Marina Fabbi, Silvano Ferrini

Published Dec 9, 2015 · Vol. 6, No. 41 · pp. 43267-43280

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells Research Paper

Interferon-Î³-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation Research Paper

VE-cadherin cleavage by ovarian cancer microparticles induces Î²-catenin phosphorylation in endothelial cells Research Paper

ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells Research Paper

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling Research Paper

Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma Research Paper

Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway Research Paper

Activated T cells sustain myeloid-derived suppressor cell-mediated immune suppression Research Paper

A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer Research Paper

PKCÎ´ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling Research Paper

Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells Research Paper

The B56Î³3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1 Research Paper

Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome Research Paper

Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells Research Paper

UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation Research Paper

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway Research Paper

MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth Research Paper

Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells Research Paper

IL-27 induces the expression of IDO and PD-L1 in human cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells Research Paper

Interferon-Î³-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation Research Paper

VE-cadherin cleavage by ovarian cancer microparticles induces Î²-catenin phosphorylation in endothelial cells Research Paper

ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells Research Paper

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling Research Paper

Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma Research Paper

Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway Research Paper

Activated T cells sustain myeloid-derived suppressor cell-mediated immune suppression Research Paper

A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer Research Paper

PKCÎ´ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling Research Paper

Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells Research Paper

The B56Î³3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1 Research Paper

Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome Research Paper

Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells Research Paper

UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation Research Paper

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway Research Paper

MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth Research Paper

Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells Research Paper

IL-27 induces the expression of IDO and PD-L1 in human cancer cells Research Paper