The Oncosearch | Oncotarget

ATM is the primary kinase responsible for phosphorylation of Hsp90Î± after ionizing radiation Research Paper

Ameer L. Elaimy, Aarif Ahsan, Katherine Marsh, William B. Pratt, Dipankar Ray, Theodore S. Lawrence, Mukesh K. Nyati

Published Oct 11, 2016 · Vol. 7, No. 50 · pp. 82450-82457

7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells Research Paper

Mei-Chi Chang, Yi-Jane Chen, Eric Jein-Wein Liou, Wan-Yu Tseng, Chiu-Po Chan, Hseuh-Jen Lin, Wan-Chuen Liao, Ya-Ching Chang, Po-Yuan Jeng, Jiiang-Huei Jeng

Published Oct 11, 2016 · Vol. 7, No. 46 · pp. 74473-74483

Coordination of signalling networks and tumorigenic properties by ABL in glioblastoma cells Research Paper

Fabienne Lamballe, Sara Toscano, Filippo Conti, Maria Arechederra, Nathalie Baeza, Dominique Figarella-Branger, FranÃ§oise Helmbacher, Flavio Maina

Published Oct 9, 2016 · Vol. 7, No. 46 · pp. 74747-74767

Phosphoproteomics reveals ALK promote cell progress via RAS/ JNK pathway in neuroblastoma Research Paper

Kai Chen, Fan Lv, Guofeng Xu, Min Zhang, Yeming Wu, Zhixiang Wu

Published Oct 7, 2016 · Vol. 7, No. 46 · pp. 75968-75980

Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis Research Paper

Chongxiang Xiong, Monica V. Masucci, Xiaoxu Zhou, Na Liu, Xiujuan Zang, Evelyn Tolbert, Ting C. Zhao, Shougang Zhuang

Published Oct 6, 2016 · Vol. 7, No. 43 · pp. 69291-69308

Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing Research Paper

Q-Schick Auh, Kyung-Ran Park, Hyung-Mun Yun, Hyun-Chang Lim, Ga-Hyun Kim, Dong-Sung Lee, Youn-Chul Kim, Hyuncheol Oh, Eun-Cheol Kim

Published Oct 4, 2016 · Vol. 7, No. 48 · pp. 78320-78330

Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes Research Paper

Shih-Yu Huang, Yao-Chang Chen, Yu-Hsun Kao, Ming-Hsiung Hsieh, Yung-Kuo Lin, Cheng-Chih Chung, Ting-I Lee, Wen-Chin Tsai, Shih-Ann Chen, Yi-Jen Chen

Published Oct 4, 2016 · Vol. 7, No. 43 · pp. 69231-69242

Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis Research Paper

Shan Guan, Yanling Zhao, Jiaxiong Lu, Yang Yu, Wenjing Sun, Xinfang Mao, Zhenghu Chen, Xin Xu, Jessie Pan, Surong Sun, Jianhua Yang

Published Oct 4, 2016 · Vol. 7, No. 46 · pp. 75914-75925

Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-ÎºB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death Research Paper

Trinayan Kashyap, Christian Argueta, Amro Aboukameel, Thaddeus John Unger, Boris Klebanov, Ramzi M. Mohammad, Irfana Muqbil, Asfar S. Azmi, Claire Drolen, William Senapedis, Margaret Lee, Michael Kauffman, Sharon Shacham, Yosef Landesman

Published Oct 4, 2016 · Vol. 7, No. 48 · pp. 78883-78895

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma Research Paper

Atish Mohanty, Natalie Sandoval, Manasi Das, Raju Pillai, Lu Chen, Robert W. Chen, Hesham M. Amin, Michael Wang, Guido Marcucci, Dennis D. Weisenburger, Steven T. Rosen, Lan V. Pham, Vu N. Ngo

Published Oct 4, 2016 · Vol. 7, No. 45 · pp. 73558-73572

Prostate-specific membrane antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells â€œin vitroâ€ and correlating with progression â€œin vivoâ€ Research Paper

Maria Elisa Perico, Silvia Grasso, Matteo Brunelli, Guido Martignoni, Enrico Munari, Enrico Moiso, Giulio Fracasso, Tiziana Cestari, Hassan Y. Naim, Vincenzo Bronte, Marco Colombatti, Dunia Ramarli

Published Oct 3, 2016 · Vol. 7, No. 45 · pp. 74189-74202

Ran GTPase promotes cancer progression via Met receptor-mediated downstream signaling Research Paper

Hiu-Fung Yuen, Ka-Kui Chan, Angela Platt-Higgins, EL-Habib Dakir, Kyle B. Matchett, Yusuf Ahmed Haggag, Puthen V. Jithesh, Tanwir Habib, Ahmed Faheem, Fennell A. Dean, Richard Morgan, Philip S. Rudland, Mohamed El-Tanani

Published Oct 3, 2016 · Vol. 7, No. 46 · pp. 75854-75864

JWA down-regulates HER2 expression via c-Cbl and induces lapatinib resistance in human gastric cancer cells Research Paper

Ling Ma, Weiyou Zhu, Qiang Wang, Fengming Yang, Jing Qian, Tongpeng Xu, Shouyu Wang, Jianwei Zhou, Yongqian Shu

Published Sep 30, 2016 · Vol. 7, No. 44 · pp. 71790-71801

Targeting the ERK pathway for the treatment of Cushingâ€™s disease Priority Research Paper

Dongyun Zhang, Marvin Bergsneider, Marilene B. Wang, Anthony P. Heaney

Published Sep 30, 2016 · Vol. 7, No. 43 · pp. 69149-69158

Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity Research Paper

Takayuki Kishi, Taira Mayanagi, Sadahiro Iwabuchi, Toshihide Akasaka, Kenji Sobue

Published Sep 30, 2016 · Vol. 7, No. 44 · pp. 72113-72130

LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors Research Paper

Yi-Shu Wang, Jianfeng Chen, Fengmei Cui, Huibo Wang, Shuai Wang, Wei Hang, Qinghua Zeng, Cheng-Shi Quan, Ying-Xian Zhai, Jian-Wei Wang, Xiang-Feng Shen, Yong-Ping Jian, Rui-Xun Zhao, Kaitlin D. Werle, Rutao Cui, Jiyong Liang, Yu-Lin Li, Zhi-Xiang Xu

Published Sep 29, 2016 · Vol. 7, No. 45 · pp. 73389-73401

Asporin enhances colorectal cancer metastasis through activating the EGFR/Src/cortactin signaling pathway Research Paper

Huo Wu, Xiaoqian Jing, Xi Cheng, Yonggang He, Lei Hu, Haoxuan Wu, Feng Ye, Ren Zhao

Published Sep 29, 2016 · Vol. 7, No. 45 · pp. 73402-73413

Smoking-associated lung cancer prevention by blockade of the beta-adrenergic receptor-mediated insulin-like growth factor receptor activation Research Paper

Hye-Young Min, Hye-Jin Boo, Ho Jin Lee, Hyun-Ji Jang, Hye Jeong Yun, Su Jung Hwang, John Kendal Smith, Hyo-Jong Lee, Ho-Young Lee

Published Sep 29, 2016 · Vol. 7, No. 43 · pp. 70936-70947

Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-ÎºB in esophageal squamous cell carcinoma cells Research Paper

Won-Sik Shin, Yuri Hong, Hae Won Lee, Seung-Taek Lee

Published Sep 28, 2016 · Vol. 7, No. 45 · pp. 73242-73256

The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer Research Paper

Ming Yang, Haiyong Wang, Mo Zhou, Weilin Liu, Pengqun Kuang, Hao Liang, Qipeng Yuan

Published Sep 28, 2016 · Vol. 7, No. 47 · pp. 76656-76666

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ATM is the primary kinase responsible for phosphorylation of Hsp90Î± after ionizing radiation Research Paper

7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells Research Paper

Coordination of signalling networks and tumorigenic properties by ABL in glioblastoma cells Research Paper

Phosphoproteomics reveals ALK promote cell progress via RAS/ JNK pathway in neuroblastoma Research Paper

Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis Research Paper

Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing Research Paper

Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes Research Paper

Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis Research Paper

Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-ÎºB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death Research Paper

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma Research Paper

Prostate-specific membrane antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells â€œin vitroâ€ and correlating with progression â€œin vivoâ€ Research Paper

Ran GTPase promotes cancer progression via Met receptor-mediated downstream signaling Research Paper

JWA down-regulates HER2 expression via c-Cbl and induces lapatinib resistance in human gastric cancer cells Research Paper

Targeting the ERK pathway for the treatment of Cushingâ€™s disease Priority Research Paper

Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity Research Paper

LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors Research Paper

Asporin enhances colorectal cancer metastasis through activating the EGFR/Src/cortactin signaling pathway Research Paper

Smoking-associated lung cancer prevention by blockade of the beta-adrenergic receptor-mediated insulin-like growth factor receptor activation Research Paper

Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-ÎºB in esophageal squamous cell carcinoma cells Research Paper

The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

ATM is the primary kinase responsible for phosphorylation of Hsp90Î± after ionizing radiation Research Paper

7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells Research Paper

Coordination of signalling networks and tumorigenic properties by ABL in glioblastoma cells Research Paper

Phosphoproteomics reveals ALK promote cell progress via RAS/ JNK pathway in neuroblastoma Research Paper

Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis Research Paper

Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing Research Paper

Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes Research Paper

Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis Research Paper

Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-ÎºB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death Research Paper

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma Research Paper

Prostate-specific membrane antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells â€œin vitroâ€ and correlating with progression â€œin vivoâ€ Research Paper

Ran GTPase promotes cancer progression via Met receptor-mediated downstream signaling Research Paper

JWA down-regulates HER2 expression via c-Cbl and induces lapatinib resistance in human gastric cancer cells Research Paper

Targeting the ERK pathway for the treatment of Cushingâ€™s disease Priority Research Paper

Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity Research Paper

LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors Research Paper

Asporin enhances colorectal cancer metastasis through activating the EGFR/Src/cortactin signaling pathway Research Paper

Smoking-associated lung cancer prevention by blockade of the beta-adrenergic receptor-mediated insulin-like growth factor receptor activation Research Paper

Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-ÎºB in esophageal squamous cell carcinoma cells Research Paper

The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer Research Paper

Prostate-specific membrane antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells â€œin vitroâ€ and correlating with progression â€œin vivoâ€ Research Paper