The Oncosearch | Oncotarget

Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget Review

Diana Hatoum, Nahal Haddadi, Yiguang Lin, Najah T. Nassif, Eileen M. McGowan

Published Mar 18, 2017 · Vol. 8, No. 22 · pp. 36898-36929

Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models Research Paper

Chao Jian, Mei-Juan Tu, Pui Yan Ho, Zhijian Duan, Qianyu Zhang, Jing-Xin Qiu, Ralph W. DeVere White, Theodore Wun, Primo N. Lara, Kit S. Lam, Ai-Xi Yu, Ai-Ming Yu

Published Mar 18, 2017 · Vol. 8, No. 19 · pp. 30742-30755

Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset Research Paper

Sathish K.R. Padi, Libia A. Luevano, Ningfei An, Ritu Pandey, Neha Singh, Jin H. Song, Jon C. Aster, Xue-Zhong Yu, Shikhar Mehrotra, Andrew S. Kraft

Published Mar 17, 2017 · Vol. 8, No. 18 · pp. 30199-30216

Recombinant human erythropoietin stimulates melanoma tumor growth through activation of initiation factor eIF4E Research Paper

Annabelle Julius, Anjali Desai, Raymond L. Yung

Published Mar 17, 2017 · Vol. 8, No. 18 · pp. 30317-30327

Signal transduction growth factors: the effective governance of transcription and cellular adhesion in cancer invasion Review

Marina Di Domenico, Antonio Giordano

Published Mar 16, 2017 · Vol. 8, No. 22 · pp. 36869-36884

Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated Î²-catenin stabilization Research Paper

Jeetendra Kumar Nag, Arun Kancharla, Myriam Maoz, Hagit Turm, Daniel Agranovich, Cheddi Lal Gupta, Beatrice Uziely, Rachel Bar-Shavit

Published Mar 16, 2017 · Vol. 8, No. 24 · pp. 38650-38667

Anti-helminthic niclosamide inhibits Ras-driven oncogenic transformation via activation of GSK-3 Research Paper

Sung Yong Ahn, Ji Hye Yang, Nam Hee Kim, Kyungro Lee, Yong Hoon Cha, Jun Seop Yun, Hee Eun Kang, Yoonmi Lee, Jiwon Choi, Hyun Sil Kim, Jong In Yook

Published Mar 16, 2017 · Vol. 8, No. 19 · pp. 31856-31863

Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with pre-adipocytes/adipocytes Research Paper

Ting Wang, Zhihui Zhang, Ke Wang, Jinshu Wang, Yayun Jiang, Jing Xia, Liyao Gou, Mengyao Liu, Lan Zhou, Tongchuan He, Yan Zhang

Published Mar 16, 2017 · Vol. 8, No. 22 · pp. 35890-35901

Hyperglycemia via activation of thromboxane A2 receptor impairs the integrity and function of blood-brain barrier in microvascular endothelial cells Research Paper

Zhihong Zhao, Jue Hu, Xiaoping Gao, Hui Liang, Haiya Yu, Suosi Liu, Zhan Liu

Published Mar 16, 2017 · Vol. 8, No. 18 · pp. 30030-30038

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis Research Paper

Haibo Wang, Bin Peng, Raj K. Pandita, David A. Engler, RisÃ« K. Matsunami, Pavana M. Hegde, Brian E. Butler, Tej K. Pandita, Sankar Mitra, Bo Xu, Muralidhar L. Hegde

Published Mar 15, 2017 · Vol. 8, No. 30 · pp. 48671-48687

Inhibitor of Tec kinase, LFM-A13, decreases pro-inflammatory mediators production in LPS-stimulated RAW264.7 macrophages via NF-ÎºB pathway Research Paper

Fei Wang, Wei Zhang, Chao Wang, Xu Fang, Hao Cheng, Sheng Liu, Xu-Lin Chen

Published Mar 15, 2017 · Vol. 8, No. 21 · pp. 34099-34110

Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors Research Paper

John E. Bisi, Jessica A. Sorrentino, Jamie L. Jordan, David D. Darr, Patrick J. Roberts, Francis X. Tavares, Jay C. Strum

Published Mar 15, 2017 · Vol. 8, No. 26 · pp. 42343-42358

A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer Research Paper

Zu-Jun Sun, Yi Wu, Wei-Hua Hou, Yu-Xiong Wang, Qing-Yun Yuan, Hui-Jie Wang, Min Yu

Published Mar 14, 2017 · Vol. 8, No. 17 · pp. 29067-29079

The Spi1/PU.1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemia Research Paper

Pauline RimmelÃ©, Michela Esposito, Laure DelestrÃ©, Jean-Hugues Guervilly, Maya Ridinger-Saison, Emmanuelle Despras, FranÃ§oise Moreau-Gachelin, Filippo Rosselli, Christel Guillouf

Published Mar 14, 2017 · Vol. 8, No. 23 · pp. 37104-37114

Lipid degradation promotes prostate cancer cell survival Research Paper

Harri M. Itkonen, Michael Brown, Alfonso Urbanucci, Gregory Tredwell, Chung Ho Lau, Stefan Barfeld, Claire Hart, Ingrid J. Guldvik, Mandeep Takhar, Hannelore V. Heemers, Nicholas Erho, Katarzyna Bloch, Elai Davicioni, Rita Derua, Etienne Waelkens, James L. Mohler, Noel Clarke, Johan V. Swinnen, Hector C. Keun, Ole P. Rekvig, Ian G. Mills

Published Mar 11, 2017 · Vol. 8, No. 24 · pp. 38264-38275

Stat3 phosphorylation is required for embryonic stem cells ground state maintenance in 2i culture media Research Paper

Dan Wang, Hui Sang, Kaiyue Zhang, Yan Nie, Shuang Zhao, Yan Zhang, Ningning He, Yuebing Wang, Yang Xu, Xiaoyan Xie, Zongjin Li, Na Liu

Published Mar 10, 2017 · Vol. 8, No. 19 · pp. 31227-31237

Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells Research Paper

Chia-Hao Chang, Krikor Bijian, Dinghong Qiu, Jie Su, Amine Saad, Michael S. Dahabieh, Wilson H. Miller Jr., Moulay A. Alaoui-Jamali

Published Mar 10, 2017 · Vol. 8, No. 19 · pp. 31199-31214

Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion Research Paper

Chongxiang Xiong, Xiujuan Zang, Xiaoxu Zhou, Lirong Liu, Monica V. Masucci, Jinhua Tang, Xuezhu Li, Na Liu, George Bayliss, Ting C. Zhao, Shougang Zhuang

Published Mar 10, 2017 · Vol. 8, No. 19 · pp. 31238-31253

PGE₂/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells Research Paper

Lorenzo Bazzani, Sandra Donnini, Federica Finetti, Gerhard Christofori, Marina Ziche

Published Mar 10, 2017 · Vol. 8, No. 19 · pp. 31270-31287

Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain Research Paper

Jia-Wei Min, Wei-Lin Kong, Song Han, Nageeb Bsoul, Wan-Hong Liu, Xiao-Hua He, Russell M. Sanchez, Bi-Wen Peng

Published Mar 10, 2017 · Vol. 8, No. 15 · pp. 25513-25524

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Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget Review

Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models Research Paper

Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset Research Paper

Recombinant human erythropoietin stimulates melanoma tumor growth through activation of initiation factor eIF4E Research Paper

Signal transduction growth factors: the effective governance of transcription and cellular adhesion in cancer invasion Review

Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated Î²-catenin stabilization Research Paper

Anti-helminthic niclosamide inhibits Ras-driven oncogenic transformation via activation of GSK-3 Research Paper

Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with pre-adipocytes/adipocytes Research Paper

Hyperglycemia via activation of thromboxane A2 receptor impairs the integrity and function of blood-brain barrier in microvascular endothelial cells Research Paper

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis Research Paper

Inhibitor of Tec kinase, LFM-A13, decreases pro-inflammatory mediators production in LPS-stimulated RAW264.7 macrophages via NF-ÎºB pathway Research Paper

Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors Research Paper

A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer Research Paper

The Spi1/PU.1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemia Research Paper

Lipid degradation promotes prostate cancer cell survival Research Paper

Stat3 phosphorylation is required for embryonic stem cells ground state maintenance in 2i culture media Research Paper

Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells Research Paper

Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion Research Paper

PGE₂/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells Research Paper

Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget Review

Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models Research Paper

Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset Research Paper

Recombinant human erythropoietin stimulates melanoma tumor growth through activation of initiation factor eIF4E Research Paper

Signal transduction growth factors: the effective governance of transcription and cellular adhesion in cancer invasion Review

Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated Î²-catenin stabilization Research Paper

Anti-helminthic niclosamide inhibits Ras-driven oncogenic transformation via activation of GSK-3 Research Paper

Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with pre-adipocytes/adipocytes Research Paper

Hyperglycemia via activation of thromboxane A2 receptor impairs the integrity and function of blood-brain barrier in microvascular endothelial cells Research Paper

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis Research Paper

Inhibitor of Tec kinase, LFM-A13, decreases pro-inflammatory mediators production in LPS-stimulated RAW264.7 macrophages via NF-ÎºB pathway Research Paper

Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors Research Paper

A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer Research Paper

The Spi1/PU.1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemia Research Paper

Lipid degradation promotes prostate cancer cell survival Research Paper

Stat3 phosphorylation is required for embryonic stem cells ground state maintenance in 2i culture media Research Paper

Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells Research Paper

Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion Research Paper

PGE2/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells Research Paper

Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain Research Paper

PGE₂/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells Research Paper