The Oncosearch | Oncotarget

Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway Research Paper

Rui Cao, Zhe Meng, Tongzu Liu, Gang Wang, Guofeng Qian, Tingting Cao, Xinyuan Guan, Hancai Dan, Yu Xiao, Xinghuan Wang

Published Sep 20, 2016 · Vol. 7, No. 45 · pp. 72941-72960

SMAD4 loss enables EGF, TGFÎ²1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells Research Paper

Stefania Moz, Daniela Basso, Dania Bozzato, Paola Galozzi, Filippo Navaglia, Ola H. Negm, Giorgio Arrigoni, Carlo-Federico Zambon, Andrea Padoan, Paddy Tighe, Ian Todd, Cinzia Franchin, Sergio Pedrazzoli, Leonardo Punzi, Mario Plebani

Published Sep 16, 2016 · Vol. 7, No. 43 · pp. 69927-69944

A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL Clinical Research Papers

Nitin Jain, Kumudha Balakrishnan, Alessandra Ferrajoli, Susan M. Oâ€™Brien, Jan A. Burger, Tapan M. Kadia, Jorge E. Cortes, Mary L. Ayres, Francesco Paolo Tambaro, Michael J. Keating, Varsha Gandhi, William G. Wierda

Published Sep 15, 2016 · Vol. 8, No. 13 · pp. 22104-22112

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC Research Paper

Francesco Perrone, Gustavo Baldassarre, Stefano Indraccolo, Simona Signoriello, Gennaro Chiappetta, Franca Esposito, Gabriella Ferrandina, Renato Franco, Delia Mezzanzanica, Maura Sonego, Elisabetta Zulato, Gian F. Zannoni, Vincenzo Canzonieri, Giovanni Scambia, Roberto Sorio, Antonella Savarese, Enrico Breda, Paolo Scollo, Antonella Ferro, Stefano Tamberi, Antonio Febbraro, Donato Natale, Massimo Di Maio, Daniela Califano, GiosuÃ¨ Scognamiglio, Domenica Lorusso, Silvana Canevari, Simona Losito, Ciro Gallo, Sandro Pignata

Published Sep 15, 2016 · Vol. 7, No. 45 · pp. 72654-72661

Shikonin potentiates the effect of arsenic trioxide against human hepatocellular carcinoma in vitro and in vivo Research Paper

Jingjing Song, Zhongwei Zhao, Xiaoxi Fan, Minjiang Chen, Xingyao Cheng, Dengke Zhang, Fazong Wu, Xihui Ying, Jiansong Ji

Published Sep 15, 2016 · Vol. 7, No. 43 · pp. 70504-70515

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial Clinical Research Papers

Emilie Desportes, Mathilde Wagner, Maud Kamal, Anne Vincent Salomon, Gabrielle Deniziaut, GaÃ«lle Pierron, Etienne Rouleau, Thomas Jouffroy, Christophe Le Tourneau, Xavier Paoletti, Vincent Servois

Published Sep 15, 2016 · Vol. 8, No. 1 · pp. 1760-1773

Heterozygous mutation of cysteine₅₂₈ in XPO1 is sufficient for resistance to selective inhibitors of nuclear export Research Paper

Jasper Edgar Neggers, Els Vanstreels, Erkan Baloglu, Sharon Shacham, Yosef Landesman, Dirk Daelemans

Published Sep 13, 2016 · Vol. 7, No. 42 · pp. 68842-68850

DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation Research Paper

Li Lu, Yanrong Lv, Ji Dong, Shaohua Hu, Ruiyun Peng

Published Sep 12, 2016 · Vol. 7, No. 45 · pp. 72795-72806

Predictive value of homocysteine for depression after acute coronary syndrome Clinical Research Papers

Hee Ju Kang, Robert Stewart, Kyung Yeol Bae, Sung Wan Kim, Il Seon Shin, Hyuno Kang, Won Jin Moon, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Jin Sang Yoon, Jae Min Kim

Published Sep 10, 2016 · Vol. 7, No. 42 · pp. 69032-69040

Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-Î² signaling pathway Research Paper

Amber A. Bokhari, Tabari M. Baker, Batsukh Dorjbal, Sana Waheed, Christopher M. Zahn, Chad A. Hamilton, G. Larry Maxwell, Viqar Syed

Published Sep 10, 2016 · Vol. 7, No. 43 · pp. 69733-69748

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status Research Paper

Kenney R. Roodakker, Tamador Elsir, Per-Henrik D. Edqvist, Daniel HÃ¤gerstrand, Joseph Carlson, Malgorzata Lysiak, Roger Henriksson, Fredrik PontÃ©n, Johan Rosell, Peter SÃ¶derkvist, Roger Stupp, Elena Tchougounova, Monica NistÃ©r, Annika MalmstrÃ¶m, Anja Smits

Published Sep 10, 2016 · Vol. 7, No. 45 · pp. 72431-72442

Diisopropylamine dichloroacetate enhances radiosensitization in esophageal squamous cell carcinoma by increasing mitochondria-derived reactive oxygen species levels Research Paper

Gaochao Dong, Qiang Chen, Feng Jiang, Decai Yu, Qixing Mao, Wenjie Xia, Run Shi, Jie Wang, Lin Xu

Published Sep 8, 2016 · Vol. 7, No. 42 · pp. 68170-68178

Role of TP53 mutations in triple negative and HER2-positive breast cancer treated with neoadjuvant anthracycline/taxane-based chemotherapy Priority Research Paper

Silvia Darb-Esfahani, Carsten Denkert, Albrecht Stenzinger, Christoph Salat, Bruno Sinn, Christian Schem, Volker Endris, Peter Klare, Wolfgang Schmitt, Jens-Uwe Blohmer, Wilko Weichert, Markus MÃ¶bs, Hans Tesch, Sherko KÃ¼mmel, Peter Sinn, Christian Jackisch, Manfred Dietel, Toralf Reimer, Sherene Loi, Michael Untch, Gunter von Minckwitz, Valentina Nekljudova, Sibylle Loibl

Published Sep 7, 2016 · Vol. 7, No. 42 · pp. 67686-67698

DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically Research Paper

Li-liang Xia, Ya-bin Tang, Fei-fei Song, Ling Xu, Ping Ji, Shu-jun Wang, Ji-min Zhu, Yong Zhang, Guo-ping Zhao, Ying Wang, Tao-tao Liu

Published Sep 6, 2016 · Vol. 7, No. 42 · pp. 68623-68637

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication Research Paper

Seong Joo Koo, Amaury E. FernÃ¡ndez-MontalvÃ¡n, Volker Badock, Christopher J. Ott, Simon J. Holton, Oliver von Ahsen, Joern Toedling, Sarah Vittori, James E. Bradner, MÃ¡tyÃ¡s GorjÃ¡nÃ¡cz

Published Sep 6, 2016 · Vol. 7, No. 43 · pp. 70323-70335

Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells Research Paper

Yadong Wang, Haiyu Wang, Teng Pan, Li Li, Jiangmin Li, Haiyan Yang

Published Sep 2, 2016 · Vol. 7, No. 39 · pp. 64360-64370

Thermo-sensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors Research Paper

Lili Huang, Ming Shen, Rongxin Li, Xiangyu Zhang, Ying Sun, Pei Gao, Hao Fu, Hongqiang Liu, Yang He, Yuqing Du, Jun Cao, Yourong Duan

Published Sep 1, 2016 · Vol. 7, No. 45 · pp. 73280-73291

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment Research Paper

Bregje van Oorschot, Giovanna Granata, Simone Di Franco, Rosemarie ten Cate, Hans M. Rodermond, Matilde Todaro, Jan Paul Medema, Nicolaas A.P. Franken

Published Sep 1, 2016 · Vol. 7, No. 40 · pp. 65504-65513

Discovery and clinical introduction of first-in-class imipridone ONC201 Review

Joshua E. Allen, C. Leah B. Kline, Varun V. Prabhu, Jessica Wagner, Jo Ishizawa, Neel Madhukar, Avital Lev, Marie Baumeister, Lanlan Zhou, Amriti Lulla, Martin Stogniew, Lee Schalop, Cyril Benes, Howard L. Kaufman, Richard S. Pottorf, B. Rao Nallaganchu, Gary L. Olson, Fahd Al-Mulla, Madeleine Duvic, Gen Sheng Wu, David T. Dicker, Mala K. Talekar, Bora Lim, Olivier Elemento, Wolfgang Oster, Joseph Bertino, Keith Flaherty, Michael L. Wang, Gautam Borthakur, Michael Andreeff, Mark Stein, Wafik S. El-Deiry

Published Sep 1, 2016 · Vol. 7, No. 45 · pp. 74380-74392

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Haeseong Park, Ignacio Garrido-Laguna, Aung Naing, Siqing Fu, Gerald S. Falchook, Sarina A. Piha-Paul, Jennifer J. Wheler, David S. Hong, Apostolia M. Tsimberidou, Vivek Subbiah, Ralph G. Zinner, Ahmed O. Kaseb, Shreyaskumar Patel, Michelle A. Fanale, Vivianne M. Velez-Bravo, Funda Meric-Bernstam, Razelle Kurzrock, Filip Janku

Published Aug 31, 2016 · Vol. 7, No. 41 · pp. 67521-67531

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Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway Research Paper

SMAD4 loss enables EGF, TGFÎ²1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells Research Paper

A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL Clinical Research Papers

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC Research Paper

Shikonin potentiates the effect of arsenic trioxide against human hepatocellular carcinoma in vitro and in vivo Research Paper

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial Clinical Research Papers

Heterozygous mutation of cysteine₅₂₈ in XPO1 is sufficient for resistance to selective inhibitors of nuclear export Research Paper

DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation Research Paper

Predictive value of homocysteine for depression after acute coronary syndrome Clinical Research Papers

Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-Î² signaling pathway Research Paper

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status Research Paper

Diisopropylamine dichloroacetate enhances radiosensitization in esophageal squamous cell carcinoma by increasing mitochondria-derived reactive oxygen species levels Research Paper

Role of TP53 mutations in triple negative and HER2-positive breast cancer treated with neoadjuvant anthracycline/taxane-based chemotherapy Priority Research Paper

DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically Research Paper

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication Research Paper

Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells Research Paper

Thermo-sensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors Research Paper

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment Research Paper

Discovery and clinical introduction of first-in-class imipridone ONC201 Review

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway Research Paper

SMAD4 loss enables EGF, TGFÎ²1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells Research Paper

A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL Clinical Research Papers

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC Research Paper

Shikonin potentiates the effect of arsenic trioxide against human hepatocellular carcinoma in vitro and in vivo Research Paper

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial Clinical Research Papers

Heterozygous mutation of cysteine528 in XPO1 is sufficient for resistance to selective inhibitors of nuclear export Research Paper

DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation Research Paper

Predictive value of homocysteine for depression after acute coronary syndrome Clinical Research Papers

Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-Î² signaling pathway Research Paper

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status Research Paper

Diisopropylamine dichloroacetate enhances radiosensitization in esophageal squamous cell carcinoma by increasing mitochondria-derived reactive oxygen species levels Research Paper

Role of TP53 mutations in triple negative and HER2-positive breast cancer treated with neoadjuvant anthracycline/taxane-based chemotherapy Priority Research Paper

DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically Research Paper

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication Research Paper

Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells Research Paper

Thermo-sensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors Research Paper

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment Research Paper

Discovery and clinical introduction of first-in-class imipridone ONC201 Review

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Heterozygous mutation of cysteine₅₂₈ in XPO1 is sufficient for resistance to selective inhibitors of nuclear export Research Paper