The Oncosearch | Oncotarget

A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care. Review

Richard E. Kast, John A. Boockvar, Ansgar BrÃ¼ning, Francesco Cappello, Wen-Wei Chang, Boris Cvek, Q Ping Dou, Alfonso Duenas-Gonzalez, Thomas Efferth, Daniele Focosi, Seyed H. Ghaffari, Georg Karpel-Massler, Kirsi Ketola, Alireza Khoshnevisan, Daniel Keizman, Nicolas MagnÃ©, Christine Marosi, Kerrie McDonald, Miguel MuÃ±oz, Nathan David Sassoon, Mohammad H. Pourgholami, Iacopo Sardi, Avishay Sella, Kalkunte S. Srivenugopal, Marco Tuccori, Weiguang Wang, Christian R. Wirtz, Marc-Eric Halatsch

Published Apr 13, 2013 · Vol. 4, No. 4 · pp. 502-530

Keywords: angiotensin, aprepitant, artesunate, auranofin, captopril, cytokines, disulfiram, glioblastoma, ketoconazole, nelfinavir, neurokinin, sertraline, temozolomide

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Chetan Bettegowda, Nishant Agrawal, Yuchen Jiao, Yuxuan Wang, Laura D. Wood, Fausto J. Rodriguez, Ralph H. Hruban, Gary L. Gallia, Zev A. Binder, Callen J. Riggins, Vafi Salmasi, Gregory J. Riggins, Zachary J. Reitman, Ahmed Rasheed, Stephen Keir, Sueli Shinjo, Suely Marie, Roger McLendon, George Jallo, Bert Vogelstein, Darrell Bigner, Hai Yan, Kenneth W. Kinzler, Nickolas Papadopoulos

Published Apr 6, 2013 · Vol. 4, No. 4 · pp. 572-583

Keywords: CNS tumors, PXA, GBM, ependymoma, exomic sequencing, BRAF, mTOR

Galectin-3: a possible complementary marker to the PSA blood test Research Paper

Vitaly Balan, Yi Wang, Pratima Nangia-Makker, Dhonghyo Kho, Madhuri Bajaj, Daryn Smith, Lance Heilbrun, Avraham Raz, Elisabeth Heath

Published Mar 30, 2013 · Vol. 4, No. 4 · pp. 542-549

Keywords: PSA, Galectin-3, blood test, cleavage

Tumorigenic potential of circulating prostate tumor cells Research Paper

Filipe LF. Carvalho, Brian W. Simons, Emmanuel S. Antonarakis, Zeshaan Rasheed, Nora Douglas, Daniela Villegas, William Matsui, David M. Berman

Published Mar 5, 2013 · Vol. 4, No. 3 · pp. 413-421

Keywords: Circulating tumor cells, EpCAM, prostate cancer, prostate-specific antigen, TRAMP mouse

Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression Research Paper

Joan C Delto, Takashi Kobayashi, Mitchell C Benson, James McKiernan, Cory Abate-Shen

Published Feb 25, 2013 · Vol. 4, No. 2 · pp. 269-276

Keywords: Non-muscle invasive bladder cancer, intravesical therapy, genetically engineered mouse models, preclinical studies

Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells Research Paper

Mareike Roscher, Inis Hormann, Oliver Leib, Sebastian Marx, Josue Moreno, Erich Miltner, Claudia Friesen

Published Feb 24, 2013 · Vol. 4, No. 2 · pp. 218-230

Keywords: non-Hodgkin lymphoma, targeted alpha-therapy, anti-CD20, Bismuth-213, radioresistance, apoptosis

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Jun-jie Chen, Constantinos M. Mikelis, Yaqin Zhang, J. Silvio Gutkind, Baolin Zhang

Published Feb 23, 2013 · Vol. 4, No. 2 · pp. 206-217

Keywords: oral cancer, TRAIL, death receptors, apoptosis, Ras, oncotarget

Dual EGFR inhibition in combination with anti-VEGF treatment: A phase I clinical trial in non-small cell lung cancer Research Paper

Gerald S. Falchook, Aung Naing, David S. Hong, Ralph G. Zinner, Siqing Fu, Sarina A. Piha-Paul, Apostolia M. Tsimberidou, Sonia K. Morgan-Linnell, Yunfang Jiang, Christel C. Bastida, Jennifer J. Wheler, Razelle Kurzrock

Published Jan 14, 2013 · Vol. 4, No. 1 · pp. 118-127

Gene expression-based risk score in diffuse large B-cell lymphoma Research Paper

Caroline Bret, Bernard Klein, JÃ©rÃ´me Moreaux

Published Dec 31, 2012 · Vol. 3, No. 12 · pp. 1700-1710

Keywords: DLBCL, gene expression profile, risk score, prognosis

Enhancing the Efficacy of Drug-loaded Nanocarriers against Brain Tumors by Targeted Radiation Therapy Research Paper

Brian C. Baumann, Gary D. Kao, Abdullah Mahmud, Takamasa Harada, Joe Swift, Christina Chapman, Xiangsheng Xu, Dennis E. Discher, Jay F. Dorsey

Published Dec 23, 2012 · Vol. 4, No. 1 · pp. 64-79

Keywords: glioblastoma multiforme, nanocarrier, radiation therapy, brain tumors, chemotherapy

SOCS1 Mutation Subtypes Predict Divergent Outcomes in Diffuse Large B-Cell Lymphoma (DLBCL) Patients Research Paper

Birgit Schif, Jochen K Lennerz, Christian W Kohler, Markus Kreuz, Stefan Bentink, Ingo Melzner, Olga Ritz, Lorenz TrÃ¼mper, Markus LÃ¶ffler, Rainer Spang, Peter MÃ¶ller

Published Dec 9, 2012 · Vol. 4, No. 1 · pp. 35-47

Keywords: biomarker, SOCS, JAK/STAT, GCB

Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine Research Paper

Kyung H Yi, Jossette Axtmayer, John P Gustin, Anandita Rajpurohit, Josh Lauring

Published Nov 29, 2012 · Vol. 4, No. 1 · pp. 29-34

Keywords: AKT1, mutation, personalized, cancer, therapy

Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma Research Paper

Takashi Kinoshita, Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Hideki Enokida, Hirofumi Yoshino, Takeshi Yamasaki, Hideo Hidaka, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki

Published Nov 7, 2012 · Vol. 3, No. 11 · pp. 1386-1400

Keywords: microRNA, miR-218, tumor suppressor, focal adhesion, laminin-332, head and neck squamous cell carcinoma

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

Andrew D Beggs, Enric Domingo, Megan McGregor, Mikael Presz, Elaine Johnstone, Rachel Midgley, David Kerr, Dahmane Oukrif, Marco Novelli, Muti Abulafi, Shirley V Hodgson, Wakkas Fadhil, Mohammed Ilyas, Ian P Tomlinson

Published Oct 28, 2012 · Vol. 3, No. 11 · pp. 1348-1355

Keywords: Double strand break repair, ATM, g-H2AX, colorectal cancer, prognosis

High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells Research

Parvinder Hothi, Timothy J. Martins, LiPing Chen, Loic Deleyrolle, Jae-Geun Yoon, Brent Reynolds, Greg Foltz

Published Oct 23, 2012 · Vol. 3, No. 10 · pp. 1124-1136

Keywords: disulfiram, glioblastoma, high-throughput chemical screens, stem cells

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

Nicola Amodio, Marzia Leotta, Dina Bellizzi, Maria Teresa Di Martino, Patrizia D'Aquila, Marta Lionetti, Fernanda Fabiani, Emanuela Leone, Anna Maria GullÃ, Giuseppe Passarino, Michele Caraglia, Massimo Negrini, Antonino Neri, Antonio Giordano, Pierosandro Tagliaferri, Pierfrancesco Tassone

Published Oct 21, 2012 · Vol. 3, No. 10 · pp. 1246-1258

Keywords: miRNA, miR-29b, multiple myeloma, DNMT

Recurrent targets of aberrant somatic hypermutation in lymphoma Research Paper

Alireza Hadj Khodabakhshi, Ryan D Morin, Anthony P Fejes, Andrew J Mungall, Karen L Mungall, Madison Bolger-Munro, Nathalie A Johnson, Joseph M Connors, Randy D Gascoyne, Marco A Marra, Inanc Birol, Steven JM Jones

Published Oct 12, 2012 · Vol. 3, No. 11 · pp. 1308-1319

Keywords: Aberrant somatic hypermutation, Genome wide study, Diffuse large B-cell lymphoma, Genomic rearrangements.

Notching up a new therapeutic strategy for Non-Small Cell Lung Carcinoma (NSCLC) Editorial

Antonio Maraver, Manuel Serrano

Published Sep 20, 2012 · Vol. 3, No. 9 · pp. 917-918

Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma Research Paper

John de Groot, Ji Liang, Ling-Yuan Kong, Jun Wei, Yuji Piao, Gregory Fuller, Wei Qiao, Amy B Heimberger

Published Sep 19, 2012 · Vol. 3, No. 9 · pp. 1036-1048

Keywords: bevacizumab, anti-vascular endothelial growth factor, signal transducer and activator of transcription 3, treatment failure, invasion

DNA damage-induced activation of ATM promotes Î²-TRCP-mediated Mdm2 ubiquitination and destruction Research Paper

Zhiwei Wang, Hiroyuki Inuzuka, Jiateng Zhong, Hidefumi Fukushima, Lixin Wan, Pengda Liu, Wenyi Wei

Published Sep 11, 2012 · Vol. 3, No. 9 · pp. 1026-1035

Keywords: Mdm2, ATM, CKI, phosphorylation, beta-TRCP, ubiquitination, DNA damage

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A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care. Review

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Galectin-3: a possible complementary marker to the PSA blood test Research Paper

Tumorigenic potential of circulating prostate tumor cells Research Paper

Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression Research Paper

Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells Research Paper

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Dual EGFR inhibition in combination with anti-VEGF treatment: A phase I clinical trial in non-small cell lung cancer Research Paper

Gene expression-based risk score in diffuse large B-cell lymphoma Research Paper

Enhancing the Efficacy of Drug-loaded Nanocarriers against Brain Tumors by Targeted Radiation Therapy Research Paper

SOCS1 Mutation Subtypes Predict Divergent Outcomes in Diffuse Large B-Cell Lymphoma (DLBCL) Patients Research Paper

Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine Research Paper

Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma Research Paper

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells Research

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

Recurrent targets of aberrant somatic hypermutation in lymphoma Research Paper

Notching up a new therapeutic strategy for Non-Small Cell Lung Carcinoma (NSCLC) Editorial

Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma Research Paper

DNA damage-induced activation of ATM promotes Î²-TRCP-mediated Mdm2 ubiquitination and destruction Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care. Review

Exomic Sequencing of Four Rare Central Nervous System Tumor Types Research Paper

Galectin-3: a possible complementary marker to the PSA blood test Research Paper

Tumorigenic potential of circulating prostate tumor cells Research Paper

Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression Research Paper

Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells Research Paper

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Dual EGFR inhibition in combination with anti-VEGF treatment: A phase I clinical trial in non-small cell lung cancer Research Paper

Gene expression-based risk score in diffuse large B-cell lymphoma Research Paper

Enhancing the Efficacy of Drug-loaded Nanocarriers against Brain Tumors by Targeted Radiation Therapy Research Paper

SOCS1 Mutation Subtypes Predict Divergent Outcomes in Diffuse Large B-Cell Lymphoma (DLBCL) Patients Research Paper

Functional analysis of non-hotspot AKT1 mutants found in human breast cancers identifies novel driver mutations: implications for personalized medicine Research Paper

Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma Research Paper

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells Research

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

Recurrent targets of aberrant somatic hypermutation in lymphoma Research Paper

Notching up a new therapeutic strategy for Non-Small Cell Lung Carcinoma (NSCLC) Editorial

Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma Research Paper

DNA damage-induced activation of ATM promotes Î²-TRCP-mediated Mdm2 ubiquitination and destruction Research Paper