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A vicious cycle between acid sensing and survival signaling in myeloma cells: acid-induced epigenetic alteration Research Paper

Ryota Amachi, Masahiro Hiasa, Jumpei Teramachi, Takeshi Harada, Asuka Oda, Shingen Nakamura, Derek Hanson, Keiichiro Watanabe, Shiro Fujii, Hirokazu Miki, Kumiko Kagawa, Masami Iwasa, Itsuro Endo, Takeshi Kondo, Sumiko Yoshida, Ken-ichi Aihara, Kiyoe Kurahashi, Yoshiaki Kuroda, Hideaki Horikawa, Eiji Tanaka, Toshio Matsumoto, Masahiro Abe

Published Sep 10, 2016 · Vol. 7, No. 43 · pp. 70447-70461

The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma Research Paper

Yusuke Kamihara, Kohichi Takada, Tsutomu Sato, Yutaka Kawano, Kazuyuki Murase, Yohei Arihara, Shohei Kikuchi, Naotaka Hayasaka, Makoto Usami, Satoshi Iyama, Koji Miyanishi, Yasushi Sato, Masayoshi Kobune, Junji Kato

Published Sep 2, 2016 · Vol. 7, No. 39 · pp. 64330-64341

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Haeseong Park, Ignacio Garrido-Laguna, Aung Naing, Siqing Fu, Gerald S. Falchook, Sarina A. Piha-Paul, Jennifer J. Wheler, David S. Hong, Apostolia M. Tsimberidou, Vivek Subbiah, Ralph G. Zinner, Ahmed O. Kaseb, Shreyaskumar Patel, Michelle A. Fanale, Vivianne M. Velez-Bravo, Funda Meric-Bernstam, Razelle Kurzrock, Filip Janku

Published Aug 31, 2016 · Vol. 7, No. 41 · pp. 67521-67531

Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma Research Paper

Katarzyna NiedÅºwiecka, Mariusz DylÄ…g, Daria Augustyniak, GraÅ¼yna Majkowska-Skrobek, Magdalena Cal-BÄ…kowska, Young H. Ko, Peter L. Pedersen, Andre Goffeau, StanisÅ‚aw UÅ‚aszewski

Published Aug 25, 2016 · Vol. 7, No. 40 · pp. 65614-65626

Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma Research Paper

Katharina Blatt, Harald Herrmann, Gabriele Stefanzl, Wolfgang R. Sperr, Peter Valent

Published Aug 25, 2016 · Vol. 7, No. 40 · pp. 65627-65642

Soluble PD-L1: A biomarker to predict progression of autologous transplantation in patients with multiple myeloma Research Paper

Shang-Yi Huang, Hsiu-Hsia Lin, Chung-Wu Lin, Chi-Cheng Li, Ming Yao, Jih-Luh Tang, Hsin-An Hou, Woei Tsay, Sheng-Je Chou, Chieh-Lung Cheng, Hwei-Fang Tien

Published Aug 23, 2016 · Vol. 7, No. 38 · pp. 62490-62502

The novel compound STK405759 is a microtubule-targeting agent with potent and selective cytotoxicity against multiple myeloma in vitro and in vivo Research Paper

Gabriela Rozic, Lena Paukov, Jana Jakubikova, Dikla Ben-Shushan, Adrian Duek, Adi Leiba, Abraham Avigdor, Arnon Nagler, Merav Leiba

Published Aug 23, 2016 · Vol. 7, No. 38 · pp. 62572-62584

The independent association of mean platelet volume with overall survival in multiple myeloma Research Paper

Qiang Zhuang, Lina Xiang, Hanyan Xu, Fang Fang, Chongyun Xing, Bin Liang, Kang Yu, Jianhua Feng

Published Aug 23, 2016 · Vol. 7, No. 38 · pp. 62640-62646

Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins Research Paper

Aneta Schieferdecker, Ofer Shoshani, Benedikt Westner, Dov Zipori, Boris Fehse, Nicolaus KrÃ¶ger, Francis Ayuk

Published Aug 22, 2016 · Vol. 7, No. 41 · pp. 67061-67070

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia Research Paper

Thomas Boyer, Soizic Guihard, Christophe Roumier, Pauline Peyrouze, Fanny Gonzales, CÃ©line Berthon, Bruno Quesnel, Claude Preudhomme, HÃ©lÃ¨ne Behal, Alain Duhamel, Catherine Roche-Lestienne, Meyling Cheok

Published Aug 22, 2016 · Vol. 7, No. 38 · pp. 62377-62385

Application of PET/CT in treatment response evaluation and recurrence prediction in patients with newly-diagnosed multiple myeloma Clinical Research Papers

Ying Li, Junru Liu, Beihui Huang, Meilan Chen, Xiangwen Diao, Juan Li

Published Aug 19, 2016 · Vol. 8, No. 15 · pp. 25637-25649

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

Phaik Ju Teoh, Chonglei Bi, Chirackal Sintosebastian, Liang Seah Tay, Rafael Fonseca, Wee Joo Chng

Published Aug 12, 2016 · Vol. 7, No. 38 · pp. 61806-61819

Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma Research Paper

Petra Schneiderova, Tomas Pika, Petr Gajdos, Regina Fillerova, Pavel Kromer, Milos Kudelka, Jiri Minarik, Tomas Papajik, Vlastimil Scudla, Eva Kriegova

Published Aug 12, 2016 · Vol. 8, No. 41 · pp. 69408-69421

Frequency of expression and generation of T-cell responses against antigens on multiple myeloma cells in patients included in the GMMG-MM5 trial Research Paper

Michael Schmitt, Angela G. HÃ¼ckelhoven, Michael Hundemer, Anita Schmitt, Susanne Lipp, Martina Emde, Hans Salwender, Mathias HÃ¤nel, Katja Weisel, Uta Bertsch, Jan DÃ¼rig, Anthony D. Ho, Igor Wolfgang Blau, Hartmut Goldschmidt, Anja Seckinger, Dirk Hose

Published Aug 11, 2016 · Vol. 8, No. 49 · pp. 84847-84862

Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy Research Paper

Dominik Dytfeld, Magdalena Luczak, Tomasz Wrobel, Lidia Usnarska-Zubkiewicz, Katarzyna Brzezniakiewicz, Krzysztof Jamroziak, Krzysztof Giannopoulos, Anna Przybylowicz-Chalecka, Blazej Ratajczak, Joanna Czerwinska-Rybak, Adam Nowicki, Monika Joks, Elzbieta Czechowska, Magdalena Zawartko, Tomasz Szczepaniak, Norbert Grzasko, Marta Morawska, Maciej Bochenek, Tadeusz Kubicki, Michalina Morawska, Katarzyna Tusznio, Andrzej Jakubowiak, MieczysÅ‚aw Komarnicki

Published Aug 4, 2016 · Vol. 7, No. 35 · pp. 56726-56736

Role of micro-RNAs in drug resistance of multiple myeloma Review

Jahangir Abdi, Hou Jian, Hong Chang

Published Aug 2, 2016 · Vol. 7, No. 37 · pp. 60723-60735

Smac mimetic LCL161 overcomes protective ER stress induced by obatoclax, synergistically causing cell death in multiple myeloma Research Paper

Vijay Ramakrishnan, Marcus Gomez, Vivek Prasad, Teresa Kimlinger, Utkarsh Painuly, Bedabrata Mukhopadhyay, Jessica Haug, Lintao Bi, S. Vincent Rajkumar, Shaji Kumar

Published Aug 2, 2016 · Vol. 7, No. 35 · pp. 56253-56265

Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation Research Paper

Shardule P. Shah, Ajay K. Nooka, David L. Jaye, Nizar J. Bahlis, Sagar Lonial, Lawrence H. Boise

Published Jul 26, 2016 · Vol. 7, No. 37 · pp. 59727-59741

Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche Research Paper

Michela Colombo, Serena Galletti, Gaetano Bulfamante, Monica Falleni, Delfina Tosi, Katia Todoerti, Elisa Lazzari, Leslie A. Crews, Catriona H.M. Jamieson, Sara Ravaioli, Francesco Baccianti, Silvia Garavelli, Natalia Platonova, Antonino Neri, Raffaella Chiaramonte

Published Jul 24, 2016 · Vol. 7, No. 35 · pp. 56013-56029

Carfilzomib/pomalidomide single-agent or in combination with other agents for the management of relapsed/refractory multiple myeloma: a meta-analysis of 37 trials Review

Yandun Zou, Xiaoyan Ma, Haiying Yu, Chunling Hu, Limei Fan, Xuehong Ran

Published Jul 21, 2016 · Vol. 8, No. 24 · pp. 39805-39817

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A vicious cycle between acid sensing and survival signaling in myeloma cells: acid-induced epigenetic alteration Research Paper

The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma Research Paper

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma Research Paper

Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma Research Paper

Soluble PD-L1: A biomarker to predict progression of autologous transplantation in patients with multiple myeloma Research Paper

The novel compound STK405759 is a microtubule-targeting agent with potent and selective cytotoxicity against multiple myeloma in vitro and in vivo Research Paper

The independent association of mean platelet volume with overall survival in multiple myeloma Research Paper

Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins Research Paper

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia Research Paper

Application of PET/CT in treatment response evaluation and recurrence prediction in patients with newly-diagnosed multiple myeloma Clinical Research Papers

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma Research Paper

Frequency of expression and generation of T-cell responses against antigens on multiple myeloma cells in patients included in the GMMG-MM5 trial Research Paper

Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy Research Paper

Role of micro-RNAs in drug resistance of multiple myeloma Review

Smac mimetic LCL161 overcomes protective ER stress induced by obatoclax, synergistically causing cell death in multiple myeloma Research Paper

Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation Research Paper

Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche Research Paper

Carfilzomib/pomalidomide single-agent or in combination with other agents for the management of relapsed/refractory multiple myeloma: a meta-analysis of 37 trials Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A vicious cycle between acid sensing and survival signaling in myeloma cells: acid-induced epigenetic alteration Research Paper

The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma Research Paper

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma Research Paper

Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma Research Paper

Soluble PD-L1: A biomarker to predict progression of autologous transplantation in patients with multiple myeloma Research Paper

The novel compound STK405759 is a microtubule-targeting agent with potent and selective cytotoxicity against multiple myeloma in vitro and in vivo Research Paper

The independent association of mean platelet volume with overall survival in multiple myeloma Research Paper

Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins Research Paper

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia Research Paper

Application of PET/CT in treatment response evaluation and recurrence prediction in patients with newly-diagnosed multiple myeloma Clinical Research Papers

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma Research Paper

Frequency of expression and generation of T-cell responses against antigens on multiple myeloma cells in patients included in the GMMG-MM5 trial Research Paper

Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy Research Paper

Role of micro-RNAs in drug resistance of multiple myeloma Review

Smac mimetic LCL161 overcomes protective ER stress induced by obatoclax, synergistically causing cell death in multiple myeloma Research Paper

Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation Research Paper

Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche Research Paper

Carfilzomib/pomalidomide single-agent or in combination with other agents for the management of relapsed/refractory multiple myeloma: a meta-analysis of 37 trials Review