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Inactivation of CK1Î± in multiple myeloma empowers drug cytotoxicity by affecting AKT and Î²-catenin survival signaling pathways Research Paper

Sabrina Manni, Marilena Carrino, Martina Manzoni, Ketty Gianesin, Sara Canovas Nunes, Matteo Costacurta, Laura Quotti Tubi, Paolo Macaccaro, Elisa Taiana, Anna Cabrelle, Gregorio BarilÃ, Annalisa Martines, Renato Zambello, Laura Bonaldi, Livio Trentin, Antonino Neri, Gianpietro Semenzato, Francesco Piazza

Published Jan 14, 2017 · Vol. 8, No. 9 · pp. 14604-14619

Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression Review

Patrizia Mondello, Salvatore Cuzzocrea, Michele Navarra, Michael Mian

Published Jan 12, 2017 · Vol. 8, No. 12 · pp. 20394-20409

A phase I clinical study of autologous dendritic cell therapy in patients with relapsed or refractory multiple myeloma Clinical Research Papers

Sung-Hoon Jung, Hyun-Ju Lee, Youn-Kyung Lee, Deok-Hwan Yang, Hyeoung-Joon Kim, Joon Haeng Rhee, Frank Emmrich, Je-Jung Lee

Published Jan 10, 2017 · Vol. 8, No. 25 · pp. 41538-41548

Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases Research Paper

Chong Zhao, Xin Chen, Changshan Yang, Dan Zang, Xiaoying Lan, Siyan Liao, Peiquan Zhang, Jinjie Wu, Xiaofen Li, Ningning Liu, Yuning Liao, Hongbiao Huang, Xianping Shi, Lili Jiang, Xiuhua Liu, Q. Ping Dou, Xuejun Wang, Jinbao Liu

Published Jan 10, 2017 · Vol. 8, No. 8 · pp. 13942-13956

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions Research Paper

Mohammad Alzrigat, Alba Atienza PÃ¡rraga, Prasoon Agarwal, Hadil Zureigat, Anders Ã–sterborg, Hareth Nahi, Anqi Ma, Jian Jin, Kenneth Nilsson, Fredrik Ã–berg, Antonia Kalushkova, Helena Jernberg-Wiklund

Published Dec 30, 2016 · Vol. 8, No. 6 · pp. 10213-10224

Arg-Leu-Tyr-Glu tetrapeptide inhibits tumor progression by suppressing angiogenesis and vascular permeability via VEGF receptor-2 antagonism Research Paper

Yi-Yong Baek, Dong-Keon Lee, Joohwan Kim, Ji-Hee Kim, Wonjin Park, Taesam Kim, Sanghwa Han, Dooil Jeoung, Ji Chang You, Hansoo Lee, Moo-Ho Won, Kwon-Soo Ha, Young-Guen Kwon, Young-Myeong Kim

Published Dec 28, 2016 · Vol. 8, No. 7 · pp. 11763-11777

Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia Research Paper

Alexey Zatula, Aida Dikic, Celine Mulder, Animesh Sharma, Cathrine B. VÃ¥gbÃ¸, Mirta M.L. Sousa, Anders Waage, Geir Slupphaug

Published Dec 27, 2016 · Vol. 8, No. 12 · pp. 19427-19442

Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and Î³Î´ T cell-mediated lysis in multiple myeloma Research Paper

Chao Niu, Haofan Jin, Min Li, Shan Zhu, Lei Zhou, Feng Jin, Yulai Zhou, Dongsheng Xu, Jianting Xu, Lianjing Zhao, Shanshan Hao, Wei Li, Jiuwei Cui

Published Dec 16, 2016 · Vol. 8, No. 4 · pp. 5954-5964

Are neurological complications of monoclonal gammopathy of undetermined significance underestimated? Research Paper

Normann Steiner, Angelika SchwÃ¤rzler, Georg GÃ¶bel, Wolfgang LÃ¶scher, Julia Wanschitz, Eberhard Gunsilius

Published Dec 10, 2016 · Vol. 8, No. 3 · pp. 5081-5091

Predicting the impact of combined therapies on myeloma cell growth using a hybrid multi-scale agent-based model Research Paper

Zhiwei Ji, Jing Su, Dan Wu, Huiming Peng, Weiling Zhao, Brian Nlong Zhao, Xiaobo Zhou

Published Dec 9, 2016 · Vol. 8, No. 5 · pp. 7647-7665

Correction: A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway Correction

Zubin Zhang, Hongwu Mao, Xiaolin Du, Jingyu Zhu, Yujia Xu, Siyu Wang, Xin Xu, Peng Ji, Yang Yu, Biyin Cao, Kunkun Han, Tingjun Hou, Zhuan Xu, Yan Kong, Gaofeng Jiang, Xiaowen Tang, Chunhua Qiao, Xinliang Mao

Published Dec 6, 2016 · Vol. 7, No. 49 · pp. 81972-81972

Blocking EZH2 methylation transferase activity by GSK126 decreases stem cell-like myeloma cells Research Paper

Delong Zeng, Maoxing Liu, Jingxuan Pan

Published Dec 2, 2016 · Vol. 8, No. 2 · pp. 3396-3411

Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models Research Paper

Pengyu Huang, Ingrid Almeciga-Pinto, Matthew Jarpe, John H. van Duzer, Ralph Mazitschek, Min Yang, Simon S. Jones, Steven N. Quayle

Published Dec 1, 2016 · Vol. 8, No. 2 · pp. 2694-2707

LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter Research Paper

Yuan Liu, Yanan Wang, Chunqin Chen, Jiawen Zhang, Wenyan Qian, Yu Dong, Zhiqiang Liu, Xi Zhang, Xiaoyun Wang, Zhenbo Zhang, Xiaobing Shi, Sufang Wu

Published Nov 23, 2016 · Vol. 8, No. 7 · pp. 11329-11342

Sublethal exposure to alpha radiation (²²³Ra dichloride) enhances various carcinomasâ€™ sensitivity to lysis by antigen-specific cytotoxic T lymphocytes through calreticulin-mediated immunogenic modulation Research Paper

Anthony S. Malamas, Sofia R. Gameiro, Karin M. Knudson, James W. Hodge

Published Nov 23, 2016 · Vol. 7, No. 52 · pp. 86937-86947

Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy Research Paper

Wen Yu, De-Dong Cao, Qiu-bai Li, Hui-ling Mei, Yu Hu, Tao Guo

Published Nov 14, 2016 · Vol. 7, No. 52 · pp. 86075-86086

Elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio and decreased platelet-to-lymphocyte ratio are associated with poor prognosis in multiple myeloma Research Paper

Lihui Shi, Xiaoqi Qin, Huijun Wang, Yonghui Xia, Yuanyuan Li, Xuejing Chen, Lei Shang, Yu-Tzu Tai, Xiaoyan Feng, Prakrati Acharya, Chirag Acharya, Yan Xu, Shuhui Deng, Mu Hao, Dehui Zou, Yaozhong Zhao, Kun Ru, Lugui Qiu, Gang An

Published Nov 12, 2016 · Vol. 8, No. 12 · pp. 18792-18801

Magic year for multiple myeloma therapeutics: Key takeaways from the ASH 2015 annual meeting Review

Kejie Zhang, Aakash Desai, Dongfeng Zeng, Tiejun Gong, Peihua Lu, Michael Wang

Published Nov 11, 2016 · Vol. 8, No. 6 · pp. 10748-10759

Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse Research Paper

Patryk Krzeminski, Luis A. Corchete, Juan L. GarcÃa, LucÃa LÃ³pez-Corral, Encarna FermiÃ±Ã¡n, Eva M. GarcÃa, Ana A. MartÃn, JesÃºs M. HernÃ¡ndez-Rivas, RamÃ³n GarcÃa-Sanz, JesÃºs F. San Miguel, Norma C. GutiÃ©rrez

Published Nov 2, 2016 · Vol. 7, No. 49 · pp. 80664-80679

XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma Research Paper

Joel G. Turner, Trinayan Kashyap, Jana L. Dawson, Juan Gomez, Alexis A. Bauer, Steven Grant, Yun Dai, Kenneth H. Shain, Mark Meads, Yosef Landesman, Daniel M. Sullivan

Published Oct 28, 2016 · Vol. 7, No. 48 · pp. 78896-78909

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Inactivation of CK1Î± in multiple myeloma empowers drug cytotoxicity by affecting AKT and Î²-catenin survival signaling pathways Research Paper

Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression Review

A phase I clinical study of autologous dendritic cell therapy in patients with relapsed or refractory multiple myeloma Clinical Research Papers

Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases Research Paper

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions Research Paper

Arg-Leu-Tyr-Glu tetrapeptide inhibits tumor progression by suppressing angiogenesis and vascular permeability via VEGF receptor-2 antagonism Research Paper

Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia Research Paper

Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and Î³Î´ T cell-mediated lysis in multiple myeloma Research Paper

Are neurological complications of monoclonal gammopathy of undetermined significance underestimated? Research Paper

Predicting the impact of combined therapies on myeloma cell growth using a hybrid multi-scale agent-based model Research Paper

Correction: A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway Correction

Blocking EZH2 methylation transferase activity by GSK126 decreases stem cell-like myeloma cells Research Paper

Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models Research Paper

LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter Research Paper

Sublethal exposure to alpha radiation (²²³Ra dichloride) enhances various carcinomasâ€™ sensitivity to lysis by antigen-specific cytotoxic T lymphocytes through calreticulin-mediated immunogenic modulation Research Paper

Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy Research Paper

Elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio and decreased platelet-to-lymphocyte ratio are associated with poor prognosis in multiple myeloma Research Paper

Magic year for multiple myeloma therapeutics: Key takeaways from the ASH 2015 annual meeting Review

Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse Research Paper

XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inactivation of CK1Î± in multiple myeloma empowers drug cytotoxicity by affecting AKT and Î²-catenin survival signaling pathways Research Paper

Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression Review

A phase I clinical study of autologous dendritic cell therapy in patients with relapsed or refractory multiple myeloma Clinical Research Papers

Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases Research Paper

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions Research Paper

Arg-Leu-Tyr-Glu tetrapeptide inhibits tumor progression by suppressing angiogenesis and vascular permeability via VEGF receptor-2 antagonism Research Paper

Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia Research Paper

Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and Î³Î´ T cell-mediated lysis in multiple myeloma Research Paper

Are neurological complications of monoclonal gammopathy of undetermined significance underestimated? Research Paper

Predicting the impact of combined therapies on myeloma cell growth using a hybrid multi-scale agent-based model Research Paper

Correction: A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway Correction

Blocking EZH2 methylation transferase activity by GSK126 decreases stem cell-like myeloma cells Research Paper

Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models Research Paper

LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter Research Paper

Sublethal exposure to alpha radiation (223Ra dichloride) enhances various carcinomasâ€™ sensitivity to lysis by antigen-specific cytotoxic T lymphocytes through calreticulin-mediated immunogenic modulation Research Paper

Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy Research Paper

Elevated neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio and decreased platelet-to-lymphocyte ratio are associated with poor prognosis in multiple myeloma Research Paper

Magic year for multiple myeloma therapeutics: Key takeaways from the ASH 2015 annual meeting Review

Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse Research Paper

XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma Research Paper

Sublethal exposure to alpha radiation (²²³Ra dichloride) enhances various carcinomasâ€™ sensitivity to lysis by antigen-specific cytotoxic T lymphocytes through calreticulin-mediated immunogenic modulation Research Paper