The Oncosearch | Oncotarget

MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer Review

Lina Cekaite, Peter W. Eide, Guro E. Lind, Rolf I. Skotheim, Ragnhild A. Lothe

Published Nov 25, 2015 · Vol. 7, No. 6 · pp. 6476-6505

Different prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer Clinical Research Papers

Nicolas PÃ©cuchet, Pierre Laurent-Puig, Audrey Mansuet-Lupo, Antoine Legras, Marco Alifano, Karine Pallier, Audrey Didelot, Laure Gibault, Claire Danel, Pierre-Alexandre Just, Marc Riquet, FranÃ§oise Le Pimpec-Barthes, Diane Damotte, Elisabeth Fabre, HÃ©lÃ¨ne Blons

Published Nov 25, 2015 · Vol. 8, No. 14 · pp. 23831-23840

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Namrata Rastogi, Shivali Duggal, Shailendra Kumar Singh, Konica Porwal, Vikas Kumar Srivastava, Rakesh Maurya, Madan L.B. Bhatt, Durga Prasad Mishra

Published Nov 25, 2015 · Vol. 6, No. 41 · pp. 43310-43325

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents Priority Research Paper

Vit Sestak, Jan Stariat, Jolana Cermanova, Eliska Potuckova, Jaroslav Chladek, Jaroslav Roh, Jan Bures, Hana Jansova, Petr Prusa, Martin Sterba, Stanislav Micuda, Tomas Simunek, Danuta S. Kalinowski, Des R. Richardson, Petra Kovarikova

Published Nov 25, 2015 · Vol. 6, No. 40 · pp. 42411-42428

Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients Research Paper

Renata Duchnowska, Piotr J. Wysocki, Konstanty Korski, BogumiÅ‚a Czartoryska- ArÅ‚ukowicz, Anna NiwiÅ„ska, Marlena Orlikowska, Barbara Radecka, Maciej StudziÅ„ski, Regina Demlova, Barbara ZiÃ³Å‚kowska, Monika Merdalska, Åukasz Hajac, Paulina MyÅ›liwiec, Dorota Zuziak, Sylwia DÄ™bska-Szmich, Istvan Lang, MaÅ‚gorzata FoszczyÅ„ska-KÅ‚oda, BoÅ¼enna Karczmarek-Borowska, Anton Å»awrocki, Anna Kowalczyk, Wojciech Biernat, Jacek Jassem, for the Central and East European Oncology Group (CEEOG)

Published Nov 24, 2015 · Vol. 7, No. 1 · pp. 550-564

Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer Priority Research Paper

Teresa Di Desidero, Ping Xu, Shan Man, Guido Bocci, Robert S. Kerbel

Published Nov 24, 2015 · Vol. 6, No. 40 · pp. 42396-42410

The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells Research Paper

Christian Mayr, Andrej Wagner, Magdalena Loeffelberger, Daniela Bruckner, Martin Jakab, Frieder Berr, Pietro Di Fazio, Matthias Ocker, Daniel Neureiter, Martin Pichler, Tobias Kiesslich

Published Nov 24, 2015 · Vol. 7, No. 1 · pp. 745-758

Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations Research Paper

Shaohua Peng, Banibrata Sen, Tuhina Mazumdar, Lauren A. Byers, Lixia Diao, Jing Wang, Pan Tong, Uma Giri, John V. Heymach, Humam N. Kadara, Faye M. Johnson

Published Nov 23, 2015 · Vol. 7, No. 1 · pp. 565-579

Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-ÎºB Research Paper

Francesca Buontempo, Ester Orsini, Annalisa Lonetti, Alessandra Cappellini, Francesca Chiarini, Camilla Evangelisti, Cecilia Evangelisti, Fraia Melchionda, Andrea Pession, Alice Bertaina, Franco Locatelli, Jessika Bertacchini, Luca Maria Neri, James A. McCubrey, Alberto Maria Martelli

Published Nov 22, 2015 · Vol. 7, No. 2 · pp. 1323-1340

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex Priority Research Paper

Martin Fischer, Marianne Quaas, Annina Nickel, Kurt Engeland

Published Nov 22, 2015 · Vol. 6, No. 39 · pp. 41402-41417

An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation Research Paper

Linda Smit, Katrien Berns, Katherine Spence, W. David Ryder, Nik Zeps, Mandy Madiredjo, Roderick Beijersbergen, RenÃ© Bernards, Robert B. Clarke

Published Nov 22, 2015 · Vol. 7, No. 3 · pp. 2596-2610

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism Research Paper

Urszula Liwak-Muir, Christine C. Dobson, Thet Naing, Quinlan Wylie, Lucia Chehade, Stephen D. Baird, Pranesh K. Chakraborty, Martin Holcik

Published Nov 22, 2015 · Vol. 7, No. 2 · pp. 1439-1450

ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments Research Paper

Pingzhao Zhang, Yuanyuan Zhang, Kun Gao, Yuqi Wang, Xiaofeng Jin, Youheng Wei, Heige Saiyin, Dejie Wang, Jintao Peng, Jian Ma, Yan Tang, Reziya Wumaier, Hongxiu Yu, Yimin Dong, Haojie Huang, Long Yu, Chenji Wang

Published Nov 22, 2015 · Vol. 6, No. 39 · pp. 41550-41565

Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state Research Paper

Fulvio Santacatterina, Laura SÃ¡nchez-Cenizo, Laura Formentini, Maysa A. Mobasher, Estela Casas, Carlos B. Rueda, Inmaculada MartÃnez-Reyes, Cristina NÃºÃ±ez de Arenas, Javier GarcÃa-BermÃºdez, Juan M. Zapata, MarÃa SÃ¡nchez-AragÃ³, Jorgina SatrÃºstegui, Ãngela M. Valverde, JosÃ© M. Cuezva

Published Nov 22, 2015 · Vol. 7, No. 1 · pp. 490-508

A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer Research Paper

Published Nov 22, 2015 · Vol. 7, No. 2 · pp. 1300-1310

Epigenetic repression of PDZ-LIM domain-containing protein 2 promotes ovarian cancer via NOS2-derived nitric oxide signaling Research Paper

Linjie Zhao, Chuan Yu, Shengtao Zhou, Wayne Bond Lau, Bonnie Lau, Zhongyue Luo, Qiao Lin, Huiliang Yang, Yu Xuan, Tao Yi, Xia Zhao, Yuquan Wei

Published Nov 22, 2015 · Vol. 7, No. 2 · pp. 1408-1420

Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition Research Paper

Martina Di Modica, Lucia Sfondrini, Viola Regondi, Stefania Varchetta, Barbara Oliviero, Gabriella Mariani, Giulia Valeria Bianchi, Daniele Generali, Andrea Balsari, Tiziana Triulzi, Elda Tagliabue

Published Nov 21, 2015 · Vol. 7, No. 1 · pp. 255-265

Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes Research Paper

Kelly E. Craven, Jesse Gore, Julie L. Wilson, Murray Korc

Published Nov 18, 2015 · Vol. 7, No. 1 · pp. 323-341

APPL proteins promote TGFÎ²-induced nuclear transport of the TGFÎ² type I receptor intracellular domain Research Paper

Jie Song, Yabing Mu, Chunyan Li, Anders Bergh, Marta Miaczynska, Carl-Henrik Heldin, Marene LandstrÃ¶m

Published Nov 18, 2015 · Vol. 7, No. 1 · pp. 279-292

Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells Research Paper

Maciej Kliszczak, Hana Sedlackova, Ganesha P. Pitchai, Werner W. Streicher, Lumir Krejci, Ian D. Hickson

Published Nov 17, 2015 · Vol. 6, No. 38 · pp. 40464-40479

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MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer Review

Different prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer Clinical Research Papers

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents Priority Research Paper

Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients Research Paper

Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer Priority Research Paper

The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells Research Paper

Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations Research Paper

Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-ÎºB Research Paper

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex Priority Research Paper

An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation Research Paper

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism Research Paper

ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments Research Paper

Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state Research Paper

A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer Research Paper

Epigenetic repression of PDZ-LIM domain-containing protein 2 promotes ovarian cancer via NOS2-derived nitric oxide signaling Research Paper

Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition Research Paper

Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes Research Paper

APPL proteins promote TGFÎ²-induced nuclear transport of the TGFÎ² type I receptor intracellular domain Research Paper

Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer Review

Different prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer Clinical Research Papers

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents Priority Research Paper

Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients Research Paper

Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer Priority Research Paper

The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells Research Paper

Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations Research Paper

Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-ÎºB Research Paper

Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex Priority Research Paper

An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation Research Paper

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism Research Paper

ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments Research Paper

Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state Research Paper

A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer Research Paper

Epigenetic repression of PDZ-LIM domain-containing protein 2 promotes ovarian cancer via NOS2-derived nitric oxide signaling Research Paper

Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition Research Paper

Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes Research Paper

APPL proteins promote TGFÎ²-induced nuclear transport of the TGFÎ² type I receptor intracellular domain Research Paper

Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells Research Paper