The Oncosearch | Oncotarget

Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis Research Paper

Cinzia Bersani, Mikael Huss, Stefania Giacomello, Li-Di Xu, Julie Bianchi, Sofi Eriksson, Fredrik Jerhammar, Andrey Alexeyenko, Anna Vilborg, Joakim Lundeberg, Weng-Onn Lui, Klas G. Wiman

Published Dec 11, 2015 · Vol. 7, No. 2 · pp. 1895-1911

Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells Research Paper

Sivapriya Ponnurangam, Prasad R. Dandawate, Animesh Dhar, Ossama W. Tawfik, Rajashri R. Parab, Prabhu Dutt Mishra, Prafull Ranadive, Rajiv Sharma, Girish Mahajan, Shahid Umar, Scott J. Weir, Aravind Sugumar, Roy A. Jensen, Subhash B. Padhye, Arun Balakrishnan, Shrikant Anant, Dharmalingam Subramaniam

Published Dec 11, 2015 · Vol. 7, No. 3 · pp. 3217-3232

Inferring the progression of multifocal liver cancer from spatial and temporal genomic heterogeneity Research Paper

Jie-Yi Shi, Qingfeng Xing, Meng Duan, Zhi-Chao Wang, Liu-Xiao Yang, Ying-Jun Zhao, Xiao-Ying Wang, Yun Liu, Minghua Deng, Zhen-Bin Ding, Ai-Wu Ke, Jian Zhou, Jia Fan, Ya Cao, Jiping Wang, Ruibin Xi, Qiang Gao

Published Dec 11, 2015 · Vol. 7, No. 3 · pp. 2867-2877

Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations Research Paper

Susanne Lorenz, Tale BarÃ¸y, Jinchang Sun, Torfinn Nome, Daniel VodÃ¡k, Jan-Christian Bryne, Anne-Mari HÃ¥kelien, Lynnette Fernandez-Cuesta, Birte MÃ¶hlendick, Harald Rieder, Karoly Szuhai, Olga Zaikova, Terje C. Ahlquist, Gard O. S. Thomassen, Rolf I. Skotheim, Ragnhild A. Lothe, Patrick S. Tarpey, Peter Campbell, Adrienne Flanagan, Ola Myklebost, Leonardo A. Meza-Zepeda

Published Dec 11, 2015 · Vol. 7, No. 5 · pp. 5273-5288

Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma Priority Research Paper

David J. Duffy, Aleksandar Krstic, Melinda Halasz, Thomas Schwarzl, Dirk Fey, Kristiina Iljin, Jai Prakash Mehta, Kate Killick, Jenny Whilde, Benedetta Turriziani, Saija Haapa-Paananen, Vidal Fey, Matthias Fischer, Frank Westermann, Kai-Oliver Henrich, Steffen Bannert, Desmond G. Higgins, Walter Kolch

Published Dec 11, 2015 · Vol. 6, No. 41 · pp. 43182-43201

Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression Research Paper

Bo Tang, Rui Xie, Yong Qin, Yu-Feng Xiao, Xin Yong, Lei Zheng, Hui Dong, Shi-Ming Yang

Published Dec 11, 2015 · Vol. 7, No. 10 · pp. 11364-11379

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas Research Paper

Devin G. Roller, Brian Capaldo, Stefan Bekiranov, Aaron J. Mackey, Mark R. Conaway, Emanuel F. Petricoin, Daniel Gioeli, Michael J. Weber

Published Dec 10, 2015 · Vol. 7, No. 3 · pp. 2734-2753

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

Parag P. Patwardhan, Kathryn S. Ivy, Elgilda Musi, Elisa de Stanchina, Gary K. Schwartz

Published Dec 10, 2015 · Vol. 7, No. 4 · pp. 4093-4109

Mps1 is SUMO-modified during the cell cycle Research Paper

Agnese Restuccia, Feikun Yang, Changyan Chen, Lou Lu, Wei Dai

Published Dec 10, 2015 · Vol. 7, No. 3 · pp. 3158-3170

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

Zhongqian Hu, Xinyi Wang, Haoshu Fang, Yakun Liu, Danlei Chen, Qian Zhang, Xia Liu, Daoyan Wei, Chengkui Qu, Siying Wang

Published Dec 10, 2015 · Vol. 7, No. 5 · pp. 5664-5676

Molecular classification of non-invasive breast lesions for personalised therapy and chemoprevention Research Paper

Niamh Buckley, David Boyle, Darragh McArt, Gareth Irwin, D. Paul Harkin, Tong Lioe, Stephen McQuaid, Jacqueline A. James, Perry Maxwell, Peter Hamilton, Paul B. Mullan, Manuel Salto-Tellez

Published Dec 9, 2015 · Vol. 6, No. 41 · pp. 43244-43254

Mitochondrial reactive oxygen species perturb AKT/cyclin D1 cell cycle signaling via oxidative inactivation of PP2A in lowdose irradiated human fibroblasts Research Paper

Tsutomu Shimura, Megumi Sasatani, Kenji Kamiya, Hidehiko Kawai, Yohei Inaba, Naoki Kunugita

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3559-3570

Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress Research Paper

Laurensia Yuniati, Laurens T. van der Meer, Esther Tijchon, Dorette van Ingen Schenau, Liesbeth van Emst, Marloes Levers, Sander A.L. Palit, Caroline Rodenbach, Geert Poelmans, Peter M. Hoogerbrugge, Jixiu Shan, Michael S. Kilberg, Blanca Scheijen, Frank N. van Leeuwen

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3128-3143

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

Thanh Kha Phan, Fung T. Lay, Ivan K.H. Poon, Mark G. Hinds, Marc Kvansakul, Mark D. Hulett

Published Dec 9, 2015 · Vol. 7, No. 2 · pp. 2054-2069

IL-27 induces the expression of IDO and PD-L1 in human cancer cells Research Paper

Grazia Carbotti, Gaia Barisione, Irma Airoldi, Delia Mezzanzanica, Marina Bagnoli, Simone Ferrero, Andrea Petretto, Marina Fabbi, Silvano Ferrini

Published Dec 9, 2015 · Vol. 6, No. 41 · pp. 43267-43280

Hepatitis B virus core antigen as a carrier for Chlamydia trachomatis MOMP multi-epitope peptide enhances protection against genital chlamydial infection Research Paper

Pengfei Jiang, Wangqi Du, Yirong Xiong, Yan Lv, Juan Feng, Shanli Zhu, Xiangyang Xue, Shao Chen, Lifang Zhang

Published Dec 9, 2015 · Vol. 6, No. 41 · pp. 43281-43292

Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors Research Paper

Sara Duarte-Pereira, Isabel Pereira-Castro, Sarah S. Silva, Mariana GonÃ§alves Correia, CÃ©lia Neto, LuÃs Teixeira da Costa, AntÃ³nio Amorim, Raquel M. Silva

Published Dec 9, 2015 · Vol. 7, No. 2 · pp. 1973-1983

Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells Research Paper

Yun-Ru Chen, Brittany Tsou, Shuya Hu, Huimin Ma, Xiyong Liu, Yun Yen, David K. Ann

Published Dec 9, 2015 · Vol. 7, No. 2 · pp. 1984-1999

MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC) Research Paper

Bo-Liang Liu, Kai-Xuan Sun, Zhi-Hong Zong, Shuo Chen, Yang Zhao

Published Dec 9, 2015 · Vol. 7, No. 6 · pp. 6649-6664

Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer Research Paper

Ijeoma Umelo, Amir Noeparast, Gang Chen, Marleen Renard, Caroline Geers, Johan Vansteenkiste, Philippe Giron, Olivier De Wever, Erik Teugels, Jacques De GrÃ¨ve

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3068-3083

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Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis Research Paper

Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells Research Paper

Inferring the progression of multifocal liver cancer from spatial and temporal genomic heterogeneity Research Paper

Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations Research Paper

Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma Priority Research Paper

Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression Research Paper

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas Research Paper

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

Mps1 is SUMO-modified during the cell cycle Research Paper

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

Molecular classification of non-invasive breast lesions for personalised therapy and chemoprevention Research Paper

Mitochondrial reactive oxygen species perturb AKT/cyclin D1 cell cycle signaling via oxidative inactivation of PP2A in lowdose irradiated human fibroblasts Research Paper

Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress Research Paper

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

IL-27 induces the expression of IDO and PD-L1 in human cancer cells Research Paper

Hepatitis B virus core antigen as a carrier for Chlamydia trachomatis MOMP multi-epitope peptide enhances protection against genital chlamydial infection Research Paper

Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors Research Paper

Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells Research Paper

MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC) Research Paper

Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis Research Paper

Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells Research Paper

Inferring the progression of multifocal liver cancer from spatial and temporal genomic heterogeneity Research Paper

Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations Research Paper

Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma Priority Research Paper

Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression Research Paper

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas Research Paper

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

Mps1 is SUMO-modified during the cell cycle Research Paper

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

Molecular classification of non-invasive breast lesions for personalised therapy and chemoprevention Research Paper

Mitochondrial reactive oxygen species perturb AKT/cyclin D1 cell cycle signaling via oxidative inactivation of PP2A in lowdose irradiated human fibroblasts Research Paper

Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress Research Paper

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

IL-27 induces the expression of IDO and PD-L1 in human cancer cells Research Paper

Hepatitis B virus core antigen as a carrier for Chlamydia trachomatis MOMP multi-epitope peptide enhances protection against genital chlamydial infection Research Paper

Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors Research Paper

Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells Research Paper

MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC) Research Paper

Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer Research Paper