The Oncosearch | Oncotarget

Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab Research Paper

Samantha Epistolio, Marco Cefalì, Paolo Spina, Francesca Molinari, Alessandra Movilia, Massimiliano Cergnul, Luca Mazzucchelli, Sara De Dosso, Milo Frattini, Piercarlo Saletti

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1046-1056

Keywords: RAS mutations, bevacizumab, metastatic colorectal cancer, next-generation sequencing

Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

Rami Mäkelä, Ville Härmä, Nibal Badra Fajardo, Greg Wells, Zoi Lygerou, Olle Sangfelt, Juha Kononen, Juha K. Rantala

Published May 6, 2021 · Vol. 12, No. 11 · pp. 1100-1109

Keywords: cutaneous apocrine sweat gland carcinoma, ex vivo drug screening, DNA repair, PALB2, rare cancer

CEA as a blood-based biomarker in anal cancer Research Paper

Robert Hester, Shailesh Advani, Asif Rashid, Emma Holliday, Craig Messick, Prajnan Das, Yi-Qian N. You, Cullen Taniguchi, Eugene J. Koay, Brian Bednarski, Miguel Rodriguez-Bigas, John Skibber, Robert Wolff, George J. Chang, Bruce D. Minsky, Wai Chin Foo, Nicole Rothschild, Van K. Morris, Cathy Eng

Published May 5, 2021 · Vol. 12, No. 11 · pp. 1037-1045

Keywords: carcinoembryonic antigen, squamous cell carcinoma of anal canal, anal cancer, biomarkers, HPV

FGFR1, a novel biomarker for metastatic castration-resistant prostate cancer? News

Leandro H. Gallo

Published Apr 27, 2021 · Vol. 12, No. 11 · pp. 1026-1028

Keywords: prostate cancer, metastasis, cancer stem cells, castration-resistant, tyrosine kinase inhibitors

Genomic and neoantigen evolution from primary tumor to first metastases in head and neck squamous cell carcinoma Research Paper

Charles R. Schutt, Hua Sun, Jaya Sarin Pradhan, Yvonne Saenger, Jessica Ley, Douglas Adkins, Matthew Ingham, Li Ding, Brian A. Van Tine

Published Feb 21, 2021 · Vol. 12, No. 6 · pp. 534-548

Keywords: head and neck squamous cell carcinoma, neoantigens, mutational evolution, tumor relapse, immune cell infiltration

Tumor mutational burden as a predictor of immunotherapy response in breast cancer Research Perspective

Tess A. O’Meara, Sara M. Tolaney

Published Jan 23, 2021 · Vol. 12, No. 5 · pp. 394-400

Keywords: breast cancer, immunotherapy, tumor mutational burden

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Francesco Jacopo Romano, Carmela Barbato, Maria Biglietto, Vincenzo Di Lauro, Dario Arundine, Roberto Fiorentino, Francesca Ambrosio, Maresa Cammarota, Bruno Chiurazzi, Livio Puglia, Sarah Scagliarini, Raffaella Ruocco, Carmen Mocerino, Ivana Cerillo, Maria Fiorella Brangi, Ferdinando Riccardi

Published Jan 19, 2021 · Vol. 12, No. 3 · pp. 221-229

Keywords: colorectal cancer, folinic acid, sodium levofolinate, thymidylate synthase, non oncogene addiction

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Harish Potu, Malathi Kandarpa, Luke F. Peterson, Alison Durham, Nicholas J. Donato, Moshe Talpaz

Published Jan 12, 2021 · Vol. 12, No. 3 · pp. 160-172

Keywords: melanoma, deubiquitinase (DUB) enzyme, transcription factors, USP9X, DUB inhibitor

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Rolando Pérez-Lorenzo, Stephanie O. Erjavec, Angela M. Christiano, Raphael Clynes

Published Jan 6, 2021 · Vol. 12, No. 2 · pp. 66-80

Keywords: anti-tumor antibodies, targeted therapy, immunotherapy, combination therapies, melanoma

Clinical application of liquid biopsies to detect somatic BRCA1/2 mutations and guide potential therapeutic intervention for patients with metastatic breast cancer Research Perspective

Neelima Vidula, Leif W. Ellisen, Aditya Bardia

Published Dec 28, 2020 · Vol. 12, No. 2 · pp. 63-65

Keywords: cell-free DNA, BRCA1/2, PARP inhibitor, metastatic breast cancer, plasma based genotyping

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Juyeon Ko, April N. Meyer, Martin Haas, Daniel J. Donoghue

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 22-36

Keywords: metastatic castrate-resistant prostate cancer, spheroid culture, tyrosine kinase inhibitor

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper

Ahmed Elhassanny, Rene Escobedo, Daniel Ladin, Colin Burns, Rukiyah Van Dross

Published Dec 22, 2020 · Vol. 11, No. 52 · pp. 4788-4802

Keywords: calreticulin, endoplasmic reticulum stress, dendritic cells, endocannabinoid metabolite

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

Krastan B. Blagoev, Roumen Iordanov, Mengxi Zhou, Tito Fojo, Susan E. Bates

Published Dec 19, 2020 · Vol. 12, No. 1 · pp. 15-21

Keywords: drug resistance, metastatic prostate cancer, exponential growth, tumor kinetics, cancer stem cells

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Divya Bhagirath, Thao Ly Yang, Theresa Akoto, Nikhil Patel, Laura Z. Tabatabai, Sharanjot Saini

Published Dec 15, 2020 · Vol. 11, No. 51 · pp. 4681-4692

Keywords: miR-4287, prostate cancer, chromosome 8p, EMT, SLUG

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya, George Ansstas

Published Dec 13, 2020 · Vol. 11, No. 52 · pp. 4836-4844

Keywords: metastatic melanoma, immune checkpoint inhibitor, temozolomide, acquired resistance, beta-2 microglobulin

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Yvonne Cornejo, Min Li, Thanh H. Dellinger, Rachael Mooney, Masmudur M. Rahman, Grant McFadden, Karen S. Aboody, Mohamed Hammad

Published Dec 8, 2020 · Vol. 11, No. 51 · pp. 4693-4698

Keywords: oncolytic virotherapy, myxoma, NSCs, ovarian cancer

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Vishnu S. Mishra, Naveen Kumar, Masoom Raza, Seema Sehrawat

Published Dec 2, 2020 · Vol. 11, No. 51 · pp. 4754-4769

Keywords: precision neuroOncology, combination therapy, glioblastoma multiforme, pharmacological intervention, cytokine based proteomics

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Pascale Tomasini, Fabrice Barlesi, Sophie Gilles, Isabelle Nanni-Metellus, Riccardo Soffietti, Emilie Denicolai, Eric Pellegrino, Emilie Bialecki, L’Houcine Ouafik, Philippe Metellus

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4648-4654

Keywords: lung cancer, brain metastasis, whole exome sequencing, comparison, mutations

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

Paloma Bragado, Patricia Fernández-Nogueira, Neus Carbó, Pere Gascón

Published Nov 23, 2020 · Vol. 11, No. 49 · pp. 4541-4543

Keywords: breast cancer, TAFs, FGFR2, FGF5, trastuzumab

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Alec J. Kacew, Harita Dharaneeswaran, Gabriel J. Starrett, Manisha Thakuria, Nicole R. LeBoeuf, Ann W. Silk, James A. DeCaprio, Glenn J. Hanna

Published Nov 17, 2020 · Vol. 11, No. 47 · pp. 4401-4410

Keywords: cancer, genomics, immunotherapy, Merkel cell carcinoma, precision medicine

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Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab Research Paper

Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

CEA as a blood-based biomarker in anal cancer Research Paper

FGFR1, a novel biomarker for metastatic castration-resistant prostate cancer? News

Genomic and neoantigen evolution from primary tumor to first metastases in head and neck squamous cell carcinoma Research Paper

Tumor mutational burden as a predictor of immunotherapy response in breast cancer Research Perspective

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Clinical application of liquid biopsies to detect somatic BRCA1/2 mutations and guide potential therapeutic intervention for patients with metastatic breast cancer Research Perspective

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab Research Paper

Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

CEA as a blood-based biomarker in anal cancer Research Paper

FGFR1, a novel biomarker for metastatic castration-resistant prostate cancer? News

Genomic and neoantigen evolution from primary tumor to first metastases in head and neck squamous cell carcinoma Research Paper

Tumor mutational burden as a predictor of immunotherapy response in breast cancer Research Perspective

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Clinical application of liquid biopsies to detect somatic BRCA1/2 mutations and guide potential therapeutic intervention for patients with metastatic breast cancer Research Perspective

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ12,14 prostamide J2 Research Paper

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper