Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper
Keywords: EphrinB2, EphB4, HNSCC, pembrolizumab, HPV-negative
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Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status Research Paper
Keywords: TAS102, regorafenib, ERK1/2, angiogenesis, microvessel density
Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer Editorial
Keywords: ctDNA, prostate cancer, liquid biopsy, biomarker, androgen receptor pathway inhibitors
Starving cancer cells to enhance DNA damage and immunotherapy response Research Perspective
Keywords: amino acid depletion, DNA damage, DNA repair, Immunotherapy, tumor immunity
When does a melanoma metastasize? Implications for management Research Perspective
Keywords: melanoma, metastasis, time, adjuvant systemic therapy, tumor doubling time
Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas Research Paper
Keywords: sacituzumab govitecan, Trop-2, SN-38, carboplatin, cisplatin
Osteopontin induces mitochondrial biogenesis in deadherent cancer cells Research Paper
Keywords: metastasis, metabolism, anchorage independence, mitochondrial mass, peroxide
FAAH inhibition ameliorates breast cancer in a murine model Research Paper
Keywords: FAAH, breast cancer, cancer therapy, apoptosis
Addendum: Impact of Covid-19 on the management of patients with metastatic melanoma Addendum
Addendum: Site of analysis matters - Ongoing complete response to Nivolumab in a patient with HIV/HPV related metastatic anal cancer and MLH1 mutation Addendum
Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies Review
Keywords: HPV-associated malignancies, immunotherapy, circulating tumor DNA, circulating tumor cells, HPV-specific antibodies
Addendum: Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss Addendum
Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer Research Paper
Keywords: prostate cancer, metformin, metastatic, androgen deprivation therapy, clinical trial
HER3- A key survival pathway and an emerging therapeutic target in metastatic colorectal cancer and pancreatic ductal adenocarcinoma Research Perspective
Keywords: HER3, colorectal, pancreatic cancer, metastasis, microenvironment
Adopted neoplastic cells and the consequences of their existence Research Perspective
Keywords: tumor microenvironment, horizontal oncogenesis, intercellular bridges, cell fusion, cell repair
Correction: ATG4A promotes tumor metastasis by inducing the epithelial-mesenchymal transition and stem-like properties in gastric cells Correction
Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior Research Paper
Keywords: Glypican-1, TCGA, bladder carcinoma, hepatocellular carcinoma, glioma
PRRX1 induces epithelial-mesenchymal transition in oesophageal cancer Research Paper
Keywords: PRRX1, oesophageal cancer, epithelial–mesenchymal transition, cancer metastasis
Correction: Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Correction
Therapy drives genomic evolution in metastatic cancer Editorial
Keywords: cancer evolution, metastatic cancer mutations, treatment-induced mutations, GENIE