The Oncosearch | Oncotarget

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

Tom Groot Kormelink, Desmond G. Powe, Sylvia A. Kuijpers, Abulikemu Abudukelimu, Marcel H.A.M. Fens, Ebel H.E. Pieters, Willemiek W. Kassing-van der Ven, Hany O. Habashy, Ian O. Ellis, Bart R. Blokhuis, Marco Thio, Wim E. Hennink, Gert Storm, Frank A. Redegeld, Raymond M. Schiffelers

Published Mar 26, 2014 · Vol. 5, No. 10 · pp. 3159-3167

The lncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer Research Perspective

John R. Prensner, Anirban Sahu, Matthew K. Iyer, Rohit Malik, Benjamin Chandler, Irfan A. Asangani, Anton Poliakov, Ismael A. Vergara, Mohammed Alshalalfa, Robert B. Jenkins, Elai Davicioni, Felix Y. Feng, Arul M. Chinnaiyan

Published Mar 23, 2014 · Vol. 5, No. 6 · pp. 1434-1438

Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation Research Paper

Samadhi Aparicio-Siegmund, Jan Sommer, Niloufar Monhasery, Ralf Schwanbeck, Eric Keil, David FinkenstÃ¤dt, Klaus Pfeffer, Stefan Rose-John, JÃ¼rgen Scheller, Christoph Garbers

Published Mar 23, 2014 · Vol. 5, No. 8 · pp. 2131-2148

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

Harriet Wikman, Laura Westphal, Felicitas Schmid, Sirkku Pollari, Jolanthe Kropidlowski, Bettina Sielaff-Frimpong, Markus Glatzel, Jakob Matschke, Manfred Westphal, Kristiina Iljin, Heini Huhtala, Luigi Terracciano, Anne Kallioniemi, Guido Sauter, Volkmar MÃ¼ller, Isabell Witzel, Katrin Lamszus, Dirk Kemming, Klaus Pantel

Published Mar 16, 2014 · Vol. 5, No. 10 · pp. 3076-3087

17Î²-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells Research Paper

Paul K. Wright, Sarah Bowen Jones, Nicholas Ardern, Rebecca Ward, Robert B. Clarke, Federica Sotgia, Michael P. Lisanti, Goran Landberg, Rebecca Lamb

Published Mar 15, 2014 · Vol. 5, No. 10 · pp. 3055-3065

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner Priority Research Paper

Joshua Armenia, Linda Fabris, Francesca Lovat, Stefania Berton, Ilenia Segatto, Sara Dâ€™Andrea, Cristina Ivan, Luciano Cascione, George A. Calin, Carlo M. Croce, Alfonso Colombatti, Andrea Vecchione, Barbara Belletti, Gustavo Baldassarre

Published Mar 4, 2014 · Vol. 5, No. 5 · pp. 1185-1197

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

Yan Cao, Yan Xu, Lei Zhang, Zhen Li, Ying Jiang, Xiao Tian, Andrei Seluanov, Vera Gorbunova, Zhiyong Mao

Published Feb 19, 2014 · Vol. 5, No. 7 · pp. 1805-1811

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Powrnima Joshi, Barbara Jacobs, Adeeb Derakhshan, Lee R. Moore, Paul Elson, Pierre L. Triozzi, Ernest Borden, Maciej Zborowski

Published Feb 3, 2014 · Vol. 5, No. 9 · pp. 2450-2461

Keywords: circulating melanoma cells, CTC, Melan-A, S100B, magnetic separation, negative selection

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

Richard Knight, Mikhail Gostev, Sergei Ilisavskii, Anne E Willis, Gerry Melino, Alexey V Antonov

Published Jan 21, 2014 · Vol. 5, No. 3 · pp. 659-666

Keywords: oncotargets, drug action mechanisms, polypharmacology

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Pierluigi Gasparini, Luciano Cascione, Matteo Fassan, Francesca Lovat, Gulnur Guler, Serdar Balci, Cigdem Irkkan, Carl Morrison, Carlo M. Croce, Charles L. Shapiro, Kay Huebner

Published Jan 21, 2014 · Vol. 5, No. 5 · pp. 1174-1184

Keywords: Triple Negative breast cancer, microRNA, five markers, prognosis, treatments, outcome

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma Research Paper

Nicole M.A. White, Olena Masui, Leroi V. DeSouza, Olga Krakovska, Shereen Metias, Alexander D. Romaschin, R.John Honey, Robert Stewart, Kenneth Pace, Jason Lee, Michael AS. Jewett, Georg A. Bjarnason, K.W.Michael Siu, George M. Yousef

Published Jan 18, 2014 · Vol. 5, No. 2 · pp. 506-518

Keywords: kidney cancer, renal cell, carcinoma, iTRAQ, proteomics, Hsp27, urine markers

Targeting CDC25C, PLK1 and CHEK1 to overcome Docetaxel resistance induced by loss of LZTS1 in prostate cancer Research Paper

Nader Al Nakouzi, Sophie Cotteret, FrÃ©dÃ©ric Commo, Catherine Gaudin, Shanna Rajpar, Philippe Dessen, Philippe Vielh, Karim Fizazi, Anne Chauchereau

Published Jan 6, 2014 · Vol. 5, No. 3 · pp. 667-678

Keywords: Prostate cancer, chemoresistance, LZTS1, CDC25C, PLK1, CHEK1

Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers Research Perspective

Barak Rotblat, Thomas G. P. Grunewald, Gabriel Leprivier, Gerry Melino, Richard A. Knight

Published Dec 15, 2013 · Vol. 4, No. 12 · pp. 2577-2590

Keywords: anti-oxidant genes, glutathione, thioredoxin, breast cancer, lung cancer, NRF2, G6PD

Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death Research Paper

Eran Schmukler, Eya Wolfson, Roni Haklai, Galit Elad-Sfadia, Yoel Kloog, Ronit Pinkas-Kramarski

Published Nov 20, 2013 · Vol. 5, No. 1 · pp. 173-184

Keywords: Autophagy, Ras, Transformation, signal transduction.

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

He Shen, Carl D. Morrison, Jianmin Zhang, Willie Underwood III, Nuo Yang, Costa Frangou, Kevin Eng, Karen Head, Roni J. Bollag, Sravan K. Kavuri, Amyn M. Rojiani, Yingwei Li, Li Yan, Annette Hill, Anna Woloszynska-Read, Jianmin Wang, Song Liu, Donald L. Trump, Candace S. Johnson

Published Oct 29, 2013 · Vol. 4, No. 11 · pp. 2124-2134

Keywords: bladder cancer, chromosome 6p22, FISH, outcome, survival

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Sabine Becker-Weimann, Gaofeng Xiong, Saori Furuta, Ju Han, Irene Kuhn, Uri-David Akavia, Dana Pe'er, Mina J. Bissell, Ren Xu

Published Oct 14, 2013 · Vol. 4, No. 11 · pp. 2010-2020

Keywords: disorganization gene signature, p65, RelB, three-dimensional tissue structure, tissue polarity

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

Daniela Loetsch, Elisabeth Steiner, Klaus Holzmann, Sabine Spiegl-Kreinecker, Christine Pirker, Juraj Hlavaty, Helga Petznek, Balazs Hegedus, Tamas Garay, Thomas Mohr, Wolfgang Sommergruber, Walter Berger, Michael Grusch

Published Sep 1, 2013 · Vol. 4, No. 11 · pp. 1904-1918

Keywords: major vault protein, vault particles, glioblastoma multiforme, EGFR, PI3K, migration, invasion

Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin Research Paper

Bailing Chen, Miaomiao Yu, Qingshan Chang, Yongju Lu, Chitra Thakur, Danjun Ma, Zhengping Yi, Fei Chen

Published Aug 10, 2013 · Vol. 4, No. 9 · pp. 1427-1437

Keywords: mdig, H19, demethylation, prognosis

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

Alberto Gualtieri, Federica Andreola, Ilaria Sciamanna, Paola Sinibaldi Vallebona, Annalucia Serafino, Corrado Spadafora

Published Aug 9, 2013 · Vol. 4, No. 11 · pp. 1882-1893

Keywords: LINE-1 retrotransposons, SINE retrotransposons, reverse transcriptase, copy number amplification, breast cancer progression

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness Research Paper

Silvia Pegoraro, Gloria Ros, Silvano Piazza, Roberta Sommaggio, Yari Ciani, Antonio Rosato, Riccardo Sgarra, Giannino Del Sal, Guidalberto Manfioletti

Published Jul 9, 2013 · Vol. 4, No. 8 · pp. 1293-1308

Keywords: Epithelial to mesenchymal transition, stemness, HMGA1, breast cancer, invasion, metastasis, gene-signature

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

The lncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer Research Perspective

Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation Research Paper

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

17Î²-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells Research Paper

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner Priority Research Paper

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma Research Paper

Targeting CDC25C, PLK1 and CHEK1 to overcome Docetaxel resistance induced by loss of LZTS1 in prostate cancer Research Paper

Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers Research Perspective

Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death Research Paper

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin Research Paper

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

The lncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer Research Perspective

Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation Research Paper

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

17Î²-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells Research Paper

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner Priority Research Paper

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma Research Paper

Targeting CDC25C, PLK1 and CHEK1 to overcome Docetaxel resistance induced by loss of LZTS1 in prostate cancer Research Paper

Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers Research Perspective

Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death Research Paper

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin Research Paper

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness Research Paper