The Oncosearch | Oncotarget

Correction: A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer Correction

Ben Liu, Xining Zhang, Fengju Song, Qun Liu, Hongji Dai, Hong Zheng, Ping Cui, Lina Zhang, Wei Zhang, Kexin Chen

Published Dec 15, 2021

The clinician’s perspective on the 21-gene assay in early breast cancer Review

Francesco Cognetti, Giuseppe Naso

Published Dec 1, 2021 · Vol. 12, No. 26 · pp. 2514-2530

Keywords: Oncotype DX test, recurrence score results, multigene assays, genomic tests, personalized medicine

CCL20 induces colorectal cancer neoplastic epithelial cell proliferation, migration, and further CCL20 production through autocrine HGF-c-Met and MSP-MSPR signaling pathways Research Paper

Bisweswar Nandi, Jonathan Pastrana Del Valle, Mehmet K. Samur, Allison J. Gibbons, Rao H. Prabhala, Nikhil C. Munshi, Jason S. Gold

Published Nov 13, 2021 · Vol. 12, No. 24 · pp. 2323-2337

Keywords: CCL20, CCR6, HGF, MSP, colorectal cancer

Correction: The effects of pprI gene of Deinococcus radiodurans R1 on acute radiation injury of mice exposed to ⁶⁰Co γ-ray radiation Correction

Ting-Ting Chen, Wei Hua, Xi-Zhi Zhang, Bu-Hai Wang, Zhan-Shan Yang

Published Nov 5, 2021

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

Christina Schmitt, Anna-Alice Schulz, Ria Winkelmann, Kevin Smith, Peter J. Wild, Melanie Demes

Published Oct 5, 2021 · Vol. 12, No. 22 · pp. 2273-2282

Keywords: next-generation sequencing (NGS), non-small cell lung cancer (NSCLC), fluorescence in situ hybridization (FISH), MET amplification, routine diagnostics

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Monica Sharma, Isabel Castro-Piedras, Fahmida Rasha, Sabarish Ramachandran, Souad R. Sennoune, Kathryn Furr, Sharilyn Almodovar, Vadivel Ganapathy, Matthew B. Grisham, Rakhshanda Layeequr Rahman, Kevin Pruitt

Published Sep 28, 2021 · Vol. 12, No. 22 · pp. 2234-2251

Keywords: dishevelled (DVL), post-translational modification, lysine residue, gene expression, chromatin immunoprecipitation (ChIP)

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

Jessica I. Christian, Agnieszka Pastula, Andreas Herbst, Jens Neumann, Maximilian K. Marschall, Andrea Ofner, Heike Zierahn, Marlon R. Schneider, Eckhard Wolf, Michael Quante, Frank T. Kolligs

Published Sep 22, 2021 · Vol. 13, No. 1 · pp. 615-627

Keywords: DRO1, CCDC80, colorectal cancer, tumor microenvironment, tumor suppressor

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Sofia Leaf, Lindsey Carlsen, Wafik S. El-Deiry

Published Sep 15, 2021 · Vol. 12, No. 20 · pp. 1992-2005

Keywords: breast cancer, colorectal cancer, BRCA1, biomarker, early onset

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Shuai Zhao, Wafik S. El-Deiry

Published Sep 15, 2021 · Vol. 12, No. 20 · pp. 1970-1979

Keywords: Smurf2, CDK4/6 inhibition, HIF1alpha, hypoxia, cancer therapy

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

Hung Q. Doan, Leon Chen, Zeena Nawas, Heng-Huan Lee, Sirunya Silapunt, Michael Migden

Published Sep 13, 2021 · Vol. 12, No. 20 · pp. 2089-2100

Keywords: basal cell carcinoma, Hedgehog pathway inhibitor, resistance, switching, combination therapy

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Edmond J. Feris, John W. Hinds, Michael D. Cole

Published Sep 11, 2021 · Vol. 12, No. 21 · pp. 2147-2157

Keywords: cancer, drug discovery, targeted therapy, oncogene, transcription factor

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Arvin Medhat, Alla Arzumanyan, Mark A. Feitelson

Published Sep 11, 2021 · Vol. 12, No. 24 · pp. 2421-2433

Keywords: chronic liver disease, hepatocellular carcinoma, HBx, functional cure, epigenetic

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Lindsey Carlsen, Christoph Schorl, Kelsey Huntington, Liz Hernandez-Borrero, Aakash Jhaveri, Shengliang Zhang, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 8, 2021 · Vol. 12, No. 20 · pp. 2006-2021

Keywords: chemotherapy mechanism, colon cancer, 5-fluorouracil, irinotecan, oxaliplatin

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S. Slørdahl, Kristian K. Starheim

Published Sep 4, 2021 · Vol. 12, No. 21 · pp. 2158-2168

Keywords: multiple myeloma, TAK1, apoptosis, NF-κB, cancer treatment

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Angeliki Andrikopoulou, Evangelos Terpos, Spyridoula Chatzinikolaou, Kleoniki Apostolidou, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Meletios-Athanasios Dimopoulos, Flora Zagouri

Published Sep 2, 2021 · Vol. 12, No. 21 · pp. 2206-2214

Keywords: TP53 mutations, next-generation sequencing, biomarker, prognosis, breast cancer

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

Sayantani Chatterjee, Julian Ugonotti, Ling Y. Lee, Arun Everest-Dass, Rebeca Kawahara, Morten Thaysen-Andersen

Published Aug 24, 2021 · Vol. 12, No. 21 · pp. 2188-2205

Keywords: oligomannose, α1,2-mannosidase, cancer, glycomics, mass spectrometry

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Brenna M. Zimmer, Michelle E. Howell, Linlin Ma, Jeffrey R. Enders, Danielle Lehman, Eva Corey, Joseph J. Barycki, Melanie A. Simpson

Published Aug 19, 2021 · Vol. 12, No. 19 · pp. 1886-1902

Keywords: prostate cancer, castration resistance, detoxification, UDP-glucose dehydrogenase, patient-derived xenografts

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Matthew Devall, Christopher H. Dampier, Stephen Eaton, Mourad W. Ali, Virginia Díez-Obrero, Ferran Moratalla-Navarro, Jennifer Bryant, Lucas T. Jennelle, Victor Moreno, Steven M. Powell, Ulrike Peters, Graham Casey

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1863-1877

Keywords: colon organoids, microsatellite instability, smoking, single-cell deconvolution, weighted gene co-expression network analysis

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Zhiguang Xiao, Bianca Sperl, Silvia Gärtner, Tatiana Nedelko, Elvira Stacher-Priehse, Axel Ullrich, Pjotr G. Knyazev

Published Aug 14, 2021 · Vol. 12, No. 17 · pp. 1734-1735

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Correction: A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer Correction

The clinician’s perspective on the 21-gene assay in early breast cancer Review

CCL20 induces colorectal cancer neoplastic epithelial cell proliferation, migration, and further CCL20 production through autocrine HGF-c-Met and MSP-MSPR signaling pathways Research Paper

Correction: The effects of pprI gene of Deinococcus radiodurans R1 on acute radiation injury of mice exposed to ⁶⁰Co γ-ray radiation Correction

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correction: A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer Correction

The clinician’s perspective on the 21-gene assay in early breast cancer Review

CCL20 induces colorectal cancer neoplastic epithelial cell proliferation, migration, and further CCL20 production through autocrine HGF-c-Met and MSP-MSPR signaling pathways Research Paper

Correction: The effects of pprI gene of Deinococcus radiodurans R1 on acute radiation injury of mice exposed to 60Co γ-ray radiation Correction

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma Review

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Correction: The effects of pprI gene of Deinococcus radiodurans R1 on acute radiation injury of mice exposed to ⁶⁰Co γ-ray radiation Correction

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper