The Oncosearch | Oncotarget

Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma Research Paper

Xiao-Yun Zhang, Minle Li, Kai Sun, Xiao-Jie Chen, Jian Meng, Lifang Wu, Ping Zhang, Xuemei Tong, Wei-Wen Jiang

Published Dec 23, 2014 · Vol. 6, No. 1 · pp. 101-115

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

Barbie Taylor-Harding, Paul-Joseph Aspuria, Hasmik Agadjanian, Dong-Joo Cheon, Takako Mizuno, Danielle Greenberg, Jenieke R. Allen, Lindsay Spurka, Vincent Funari, Elizabeth Spiteri, Qiang Wang, Sandra Orsulic, Christine Walsh, Beth Y. Karlan, Ruprecht W. Wiedemeyer

Published Dec 22, 2014 · Vol. 6, No. 2 · pp. 696-714

Keywords: Cyclin-dependent kinase inhibitors, palbociclib, dinaciclib, Cyclin E1, ovarian cancer

Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas Research Paper

Angela Margarida Costa, Filipe Pinto, Olga Martinho, Maria JosÃ© Oliveira, Peter Jordan, Rui Manuel Reis

Published Dec 22, 2014 · Vol. 6, No. 3 · pp. 1422-1434

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis Research Paper

Xiao Xiao, Zhiguo Liu, Rui Wang, Jiayin Wang, Song Zhang, Xiqiang Cai, Kaichun Wu, Raymond C. Bergan, Li Xu, Daiming Fan

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3225-3239

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, Naoharu Takano, Weibo Luo, Haiquan Lu, John W. Bullen, Debangshu Samanta, Houjie Liang, Gregg L. Semenza

Published Dec 18, 2014 · Vol. 5, No. 24 · pp. 12509-12527

Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors Research Paper

Zeyou Wang, Jing Yang, Gang Xu, Wei Wang, Changhong Liu, Honghui Yang, Zhibin Yu, Qianqian Lei, Lan Xiao, Jing Xiong, Liang Zeng, Juanjuan Xiang, Jian Ma, Guiyuan Li, Minghua Wu

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3147-3164

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

Aaron Raymond, Bin Liu, Hong Liang, Ciamaio Wei, Michele Guindani, Yue Lu, Shoudan Liang, Lisa S. St. John, Jeff Molldrem, Lalitha Nagarajan

Published Dec 17, 2014 · Vol. 5, No. 24 · pp. 12675-12693

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Yu Fujita, Shigehiro Yagishita, Fumitaka Takeshita, Yusuke Yamamoto, Kazuyoshi Kuwano, Takahiro Ochiya

Published Dec 17, 2014 · Vol. 6, No. 5 · pp. 3335-3345

Keywords: RPN2, NSCLC, RNAi, siRNA, malignancy

Genetic alterations of histone lysine methyltransferases and their significance in breast cancer Research Paper

Lanxin Liu, Sarah Kimball, Hui Liu, Andreana Holowatyj, Zeng-Quan Yang

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2466-2482

Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer Research Paper

Dong Lin, Xin Dong, Kendric Wang, Alexander W. Wyatt, Francesco Crea, Hui Xue, Yuwei Wang, Rebecca Wu, Robert H. Bell, Anne Haegert, Sonal Brahmbhatt, Antonio Hurtado-Coll, Peter W. Gout, Ladan Fazli, Martin E. Gleave, Colin C. Collins, Yuzhuo Wang

Published Dec 11, 2014 · Vol. 6, No. 3 · pp. 1806-1820

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

Sixian Liang, Xun Peng, Xiaoli Li, Ping Yang, Linhao Xie, Yaochen Li, Caiwen Du, Guojun Zhang

Published Dec 11, 2014 · Vol. 6, No. 2 · pp. 1020-1030

Keywords: CXCR4, triple-negative breast cancer, cisplatin, chemosensitivity, apoptosis

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

Ting-Ting Chao, Cheng-Yi Wang, Yen-Lin Chen, Chih-Cheng Lai, Fang-Yu Chang, Yi-Ting Tsai, Chung-Hao H. Chao, Chung-Wai Shiau, Yuh-Chin T. Huang, Chong-Jen Yu, Kuen-Feng Chen

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2164-2179

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy Research Paper

Annalisa Petrelli, Rosachiara Carollo, Marilisa Cargnelutti, Flora Iovino, Maurizio Callari, Daniela Cimino, Matilde Todaro, Laura Rosa Mangiapane, Alessandro Giammona, Adriana Cordova, Filippo Montemurro, Daniela Taverna, Maria Grazia Daidone, Giorgio Stassi, Silvia Giordano

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2315-2330

The BRCA1/2-directed miRNA signature predicts a good prognosis in ovarian cancer patients with wild-type BRCA1/2 Research Paper

Yunyan Gu, Mengmeng Zhang, Fuduan Peng, Lei Fang, Yuanyuan Zhang, Haihai Liang, Wenbin Zhou, Lu Ao, Zheng Guo

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2397-2406

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

Teeru Bihani, Scott A. Ezell, Brendon Ladd, Shaun E. Grosskurth, Anne Marie Mazzola, Mark Pietras, Corinne Reimer, Michael Zinda, Stephen Fawell, Celina M. Dâ€™Cruz

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2407-2420

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Jara Majuelos-Melguizo, MarÃa Isabel RodrÃguez, Laura LÃ³pez-JimÃ©nez, Jose M. RodrÃguez-Vargas, Juan M. MartÃ MartÃn-Consuegra, Santiago Serrano-SÃ¡enz, Julie Gavard, J. Mariano Ruiz de AlmodÃ³var, F. Javier Oliver

Published Dec 11, 2014 · Vol. 6, No. 7 · pp. 4790-4803

Hypoxia induces a lipogenic cancer cell phenotype via HIF1Î±-dependent and -independent pathways Priority Research Paper

Alessandro Valli, Miguel Rodriguez, Loukas Moutsianas, Roman Fischer, Vita Fedele, Hong-Lei Huang, Ruud Van Stiphout, Dylan Jones, Michael Mccarthy, Maria Vinaxia, Kaori Igarashi, Maya Sato, Tomoyoshi Soga, Francesca Buffa, James Mccullagh, Oscar Yanes, Adrian Harris, Benedikt Kessler

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 1920-1941

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Cordula A. Jilg, Anett Ketscher, Eric Metzger, Barbara Hummel, Dominica Willmann, Vanessa RÃ¼sseler, Vanessa Drendel, Axel Imhof, Manfred Jung, Henriette Franz, Stefanie HÃ¶lz, Malte KrÃ¶nig, Judith M. MÃ¼ller, Roland SchÃ¼le

Published Dec 10, 2014 · Vol. 5, No. 24 · pp. 12646-12664

Genetic polymorphisms in the vitamin D pathway in relation to lung cancer risk and survival Clinical Research Papers

Jinyu Kong, Fangxiu Xu, Jinli Qu, Yu Wang, Ming Gao, Herbert Yu, Biyun Qian

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2573-2582

Clinically relevant genes and regulatory pathways associated with NRAS^Q61 mutations in melanoma through an integrative genomics approach Research Paper

Wei Jiang, Peilin Jia, Katherine E. Hutchinson, Douglas B. Johnson, Jeffrey A. Sosman, Zhongming Zhao

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2496-2508

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Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma Research Paper

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas Research Paper

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis Research Paper

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors Research Paper

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Genetic alterations of histone lysine methyltransferases and their significance in breast cancer Research Paper

Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer Research Paper

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy Research Paper

The BRCA1/2-directed miRNA signature predicts a good prognosis in ovarian cancer patients with wild-type BRCA1/2 Research Paper

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Hypoxia induces a lipogenic cancer cell phenotype via HIF1Î±-dependent and -independent pathways Priority Research Paper

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Genetic polymorphisms in the vitamin D pathway in relation to lung cancer risk and survival Clinical Research Papers

Clinically relevant genes and regulatory pathways associated with NRAS^Q61 mutations in melanoma through an integrative genomics approach Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma Research Paper

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas Research Paper

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis Research Paper

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors Research Paper

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Genetic alterations of histone lysine methyltransferases and their significance in breast cancer Research Paper

Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer Research Paper

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy Research Paper

The BRCA1/2-directed miRNA signature predicts a good prognosis in ovarian cancer patients with wild-type BRCA1/2 Research Paper

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers Research Paper

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Hypoxia induces a lipogenic cancer cell phenotype via HIF1Î±-dependent and -independent pathways Priority Research Paper

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Genetic polymorphisms in the vitamin D pathway in relation to lung cancer risk and survival Clinical Research Papers

Clinically relevant genes and regulatory pathways associated with NRASQ61 mutations in melanoma through an integrative genomics approach Research Paper

Clinically relevant genes and regulatory pathways associated with NRAS^Q61 mutations in melanoma through an integrative genomics approach Research Paper