The Oncosearch | Oncotarget

Multidimensional analysis of gene expression reveals TGFB1I1-induced EMT contributes to malignant progression of astrocytomas Research Paper

Yanwei Liu, Huimin Hu, Kuanyu Wang, Chuanbao Zhang, Yinyan Wang, Kun Yao, Pei Yang, Lei Han, Chunsheng Kang, Wei Zhang, Tao Jiang

Published Dec 31, 2014 · Vol. 5, No. 24 · pp. 12593-12606

Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Research Paper

Benny Zhitomirsky, Yehuda G. Assaraf

Published Dec 31, 2014 · Vol. 6, No. 2 · pp. 1143-1156

Keywords: Cancer, Chemotherapeutics, Multidrug resistance, Lysosomes, Drug sequestration, Lysosomal biogenesis

An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein Review

Martin F. Orth, Alex Cazes, Elke Butt, Thomas G. P. Grunewald

Published Dec 31, 2014 · Vol. 6, No. 1 · pp. 26-42

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Afua Adjeiwaa Mensah, Ivo Kwee, Eugenio Gaudio, Andrea Rinaldi, Maurilio Ponzoni, Luciano Cascione, Gianluca Fossati, Anastasios Stathis, Emanuele Zucca, Gianluca Caprini, Francesco Bertoni

Published Dec 30, 2014 · Vol. 6, No. 7 · pp. 5059-5071

Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression Research Paper

Shiyi Yu, Xiuxiu Cai, Chenxi Wu, Lele Wu, Yuzhi Wang, Yan Liu, Zhenghong Yu, Sheng Qin, Fei Ma, Jean Paul Thiery, Liming Chen

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2951-2965

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

Arjun Kalvala, Li Gao, Brittany Aguila, Tyler Reese, Gregory A. Otterson, Miguel A. Villalona-Calero, Wenrui Duan

Published Dec 30, 2014 · Vol. 6, No. 11 · pp. 8777-8787

MYC regulates the non-coding transcriptome Priority Research Paper

Jonathan R. Hart, Thomas C. Roberts, Marc S. Weinberg, Kevin V. Morris, Peter K. Vogt

Published Dec 30, 2014 · Vol. 5, No. 24 · pp. 12543-12554

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Evgeny A. Moskalev, Pouria Jandaghi, Mahdi Fallah, Mehdi Manoochehri, Sandeep K. Botla, Oleg V. Kolychev, Evgeny A. Nikitin, Vladymyr V. Bubnov, M. von Knebel Doeberitz, Oliver Strobel, Thilo Hackert, Markus W. BÃ¼chler, Nathalia Giese, Andrea Bauer, Thomas Muley, Arne Warth, Peter Schirmacher, Florian Haller, JÃ¶rg D. Hoheisel, Yasser Riazalhosseini

Published Dec 30, 2014 · Vol. 6, No. 6 · pp. 4418-4427

Keywords: DNA methylation, Cancer, Diagnosis, GHSR, Epigenetics

Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinoma Research Paper

Xijun Liu, Xingwang Zhang, Lingling Ji, Jianxin Gu, Meiling Zhou, She Chen

Published Dec 29, 2014 · Vol. 6, No. 6 · pp. 4226-4238

Keywords: Farnesoid X receptor, Î²-Catenin, TCF4, Hepatocellular carcinoma

RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel Research Paper

Jing Guo, Yage Yang, Yunsheng Yang, Enqiang Linghu, Qimin Zhan, Malcolm V. Brock, James G. Herman, Bingyong Zhang, Mingzhou Guo

Published Dec 27, 2014 · Vol. 6, No. 6 · pp. 4202-4213

Keywords: RASSF10, DNA methylation, P53 signaling, colorectal cancer, epigenetics

miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBPÎ² Research Paper

Xiao-Fei Zhang, Ke-ke Li, Lu Gao, Shang-Ze Li, Ke Chen, Jun-Bin Zhang, Di Wang, Rong-Fu Tu, Jin-Xiang Zhang, Kai-Xiong Tao, Guobin Wang, Xiao-Dong Zhang

Published Dec 27, 2014 · Vol. 6, No. 6 · pp. 4144-4158

Keywords: microRNA-191, colorectal cancer, apoptosis, C/EBPÎ², tumorigenesis.

Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth Research Paper

Guillermo N. Armaiz-Pena, Vianey Gonzalez-Villasana, Archana S. Nagaraja, Cristian Rodriguez-Aguayo, Nouara C. Sadaoui, Rebecca L. Stone, Koji Matsuo, Heather J. Dalton, Rebecca A. Previs, Nicholas B. Jennings, Piotr Dorniak, Jean M. Hansen, Jesusa M. G. Arevalo, Steve W. Cole, Susan K. Lutgendorf, Anil K. Sood, Gabriel Lopez-Berestein

Published Dec 27, 2014 · Vol. 6, No. 6 · pp. 4266-4273

Keywords: ovarian cancer, macrophages, monocytes, catecholamines, MCP1

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Ã˜ystein Bruserud, HÃ¥kon Reikvam, Hanne Fredly, JÃ¸rn Skavland, Karen-Marie Hagen, Tuyen Thy van Hoang, Annette K. Brenner, Amir Kadi, Audrey Astori, BjÃ¸rn Tore Gjertsen, Frederic Pendino

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 2794-2811

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression Research Paper

R. Mitchell Baldwin, Nasim Haghandish, Manijeh Daneshmand, Shahrier Amin, GeneviÃ¨ve Paris, Theresa J. Falls, John C. Bell, Shahidul Islam, Jocelyn CÃ´tÃ©

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3013-3032

Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer Research Paper

Jason S. Kirk, Kevin Schaarschuch, Zafardjan Dalimov, Elena Lasorsa, ShengYu Ku, Swathi Ramakrishnan, Qiang Hu, Gissou Azabdaftari, Jianmin Wang, Roberto Pili, Leigh Ellis

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3136-3146

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

Ken Maes, Eva De Smedt, Alboukadel Kassambara, Dirk Hose, Anja Seckinger, Els Van Valckenborgh, Eline Menu, Bernard Klein, Karin Vanderkerken, JÃ©rÃ´me Moreaux, Elke De Bruyne

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3319-3334

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

Youhong Liu, Lin Chen, Zhicheng Gong, Liangfang Shen, Chinghai Kao, Janet M. Hock, Lunquan Sun, Xiong Li

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3055-3070

KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers Research Paper

Kyung-Hwa Lee, Eun-Jung Ahn, Se-Jeong Oh, Ok Kim, Young-Eun Joo, Jeong-A Bae, Somy Yoon, Hyang-Hwa Ryu, Shin Jung, Kyung-Keun Kim, Jae-Hyuk Lee, Kyung-Sub Moon

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3240-3253

Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target Research Paper

Melanie F. Weingart, Jacquelyn J. Roth, Marianne Hutt-Cabezas, Tracy M. Busse, Harpreet Kaur, Antoinette Price, Rachael Maynard, Jeffrey Rubens, Isabella Taylor, Xing-gang Mao, Jingying Xu, Yasumichi Kuwahara, Sariah J. Allen, Anat Erdreich-Epstein, Bernard E. Weissman, Brent A. Orr, Charles G. Eberhart, Jaclyn A. Biegel, Eric H. Raabe

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3165-3177

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Wafa Hassen, Alboukadel Kassambara, Thierry Reme, Surinder Sahota, Anja Seckinger, Laure Vincent, Guillaume Cartron, JÃ©rÃ´me Moreaux, Dirk Hose, Bernard Klein

Published Dec 26, 2014 · Vol. 6, No. 8 · pp. 6431-6447

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Multidimensional analysis of gene expression reveals TGFB1I1-induced EMT contributes to malignant progression of astrocytomas Research Paper

Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Research Paper

An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein Review

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression Research Paper

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

MYC regulates the non-coding transcriptome Priority Research Paper

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinoma Research Paper

RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel Research Paper

miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBPÎ² Research Paper

Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth Research Paper

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression Research Paper

Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer Research Paper

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers Research Paper

Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target Research Paper

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Multidimensional analysis of gene expression reveals TGFB1I1-induced EMT contributes to malignant progression of astrocytomas Research Paper

Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Research Paper

An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein Review

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression Research Paper

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

MYC regulates the non-coding transcriptome Priority Research Paper

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinoma Research Paper

RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel Research Paper

miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBPÎ² Research Paper

Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth Research Paper

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression Research Paper

Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer Research Paper

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers Research Paper

Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target Research Paper

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers