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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

Correction: Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of p18 through claudin7 Correction

Hong Liu, Feifei Jiang, Xinshan Jia, Jing Lan, Hao Guo, Erran Li, Aihui Yan, Yan Wang

Published Dec 11, 2019 · Vol. 12, No. 19 · pp. 1966-1969

Correction: Dual-targeting nanoparticles with excellent gene transfection efficiency for gene therapy of peritoneal metastasis of colorectal cancer Correction

Ling Li, Rui Deng, Yi Su, Cheng Yang

Published Dec 11, 2019

Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation Research Paper

Melanie Haas Kucherlapati

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6913-6933

Keywords: proliferation, mutation, transcription, EGFR, lung adenocarcinoma

p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis Research Paper

Boxiao Ding, Alexander Haidurov, Ayesha Chawla, Anita Parmigiani, Gerarda van de Kamp, Alexandra Dalina, Fang Yuan, Jun Hee Lee, Peter M. Chumakov, Steven R. Grossman, Andrei V. Budanov

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6997-7009

Keywords: SESTRINs, lung cancer, mouse model, mTORC1/2, tumor suppression

An innovative diagnostic strategy for the detection of rare molecular targets to select cancer patients for tumor-agnostic treatments Research Paper

Antonio Marchetti, Alessia Di Lorito, Lara Felicioni, Fiamma Buttitta

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6957-6968

Keywords: tumor-agnostic treatments, microsatellite instability (MSI), neurotrophic receptor tyrosine kinase (NRTK), tissue microarrays (TMAs), tissue slice arrays (TSAs)

Analog-sensitive cell line identifies cellular substrates of CDK9 Research Paper

Tim-Michael Decker, Ignasi Forné, Tobias Straub, Hesham Elsaman, Guoli Ma, Nilay Shah, Axel Imhof, Dirk Eick

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6934-6943

Keywords: CDK9, protein kinase, transcription, RNA splicing, phosphoproteomics

Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a Research Paper

Sweta Sikder, Sujata Kumari, Manoj Kumar, Shrinka Sen, Namrata Bora Singhal, Srikumar Chellappan, Mukul Godbole, Pratik Chandrani, Amit Dutt, Kodaganur S. Gopinath, Tapas K. Kundu

Published Dec 3, 2019 · Vol. 10, No. 64 · pp. 6855-6869

Keywords: tumour suppressor, non-histone chromatin protein, oncomiR, matrix metalloproteinases, p53 activation

Survival correlation of immune response in human cancers Research Paper

Yuexin Liu

Published Dec 3, 2019 · Vol. 10, No. 64 · pp. 6885-6897

Keywords: overall survival, progression-free interval, immune response, immunogenicity, cancer

Correction: Gene function analysis and underlying mechanism of esophagus cancer based on microarray gene expression profiling Correction

Ying Yue, Mengjia Song, Yamin Qiao, Pupu Li, Yiqiang Yuan, Jingyao Lian, Suying Wang, Yi Zhang

Published Nov 26, 2019 · Vol. 11, No. 9 · pp. 891-892

Mesangiogenic progenitor cells are forced toward the angiogenic fate, in multiple myeloma Research Paper

Simone Pacini, Marina Montali, Francesco Mazziotta, Claudia P. Schifone, Lucia Macchia, Vittoria Carnicelli, Francesca M. Panvini, Serena Barachini, Laura Notarfranchi, Giovanni Battista Previti, Gabriele Buda, Mario Petrini

Published Nov 26, 2019 · Vol. 10, No. 63 · pp. 6781-6790

Keywords: multiple myeloma, bone marrow microenvironment, angiogenesis, osteogenesis, mesangiogenic progenitor cells

NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis Research Paper

Vasiliki Salameti, Priyanka G. Bhosale, Ashley Ames-Draycott, Kalle Sipilä, Fiona M. Watt

Published Nov 26, 2019 · Vol. 10, No. 63 · pp. 6791-6804

Keywords: oral squamous cell carcinoma (OSCC), NOTCH1, SERPINE1, ETV7/TEL2, cell adhesion

Retraction: Relationship between rs1801157 polymorphism in stromal cell-derived factor gene and systemic lupus erythematosus risk Retraction

Can Qian, Qinghua Zou, Yong Wang

Published Nov 15, 2019 · Vol. 10, No. 62 · pp. 6754-6754

Lactate induces PD-L1 in HRAS^G12V-positive oropharyngeal squamous cell carcinoma Research Paper

Alexander K. Verma, Shanta M. Messerli, W. Keith Miskimins

Published Nov 15, 2019 · Vol. 11, No. 17 · pp. 1493-1504

Keywords: oropharyngeal cancer, lactate, Ras, anti-tumor immunity, PD-L1

The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer Review

Ana Emília Goulart Lemos, Aline da Rocha Matos, Luciana Bueno Ferreira, Etel Rodrigues Pereira Gimba

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6589-6603

Keywords: PCA3, prostate cancer, biomarker, long non-coding RNA (lncRNA), clinical applications

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

Chunmei Zhao, Benjamin J. Thompson, Kelly Chen, Feng Gao, Barbara Blouw, Mathieu Marella, Susan Zimmerman, Trevor Kimbler, Sheryl Garrovillo, Jesse Bahn, Lei Huang, Zhongdong Huang, H. Michael Shepard, Sanna Rosengren, Christopher D. Thanos, Daniel C. Maneval

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6561-6576

Keywords: hyaluronan, breast cancer, xenograft, tumor microenvironment, CD44

The multifaceted anti-cancer effects of BRAF-inhibitors Review

Laura Croce, Francesca Coperchini, Flavia Magri, Luca Chiovato, Mario Rotondi

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6623-6640

Keywords: BRAF, BRAF-inhibitors, tumor microenvironment, chemokines, CXCL8

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

Douglas Jury, Iben Daugaard, Katie J. Sanders, Lise Lotte Hansen, Dritan Agalliu, Irene Munk Pedersen

Published Nov 7, 2019 · Vol. 11, No. 23 · pp. 2160-2171

Keywords: angiogenesis, miR-151a, Slug, tumor microenvironment, endothelial cell

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

David King, Xiao Dun Li, Gilberto S. Almeida, Colin Kwok, Polly Gravells, Daniel Harrison, Saoirse Burke, Albert Hallsworth, Yann Jamin, Sally George, Simon P. Robinson, Christopher J. Lord, Evon Poon, Daniel Yeomanson, Louis Chesler, Helen E. Bryant

Published Nov 6, 2019 · Vol. 11, No. 23 · pp. 2141-2159

Keywords: PARP inhibitor, neuroblastoma, MYCN, replication stress, replication fork stalling

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Fillipe Luiz Rosa do Carmo, Houem Rabah, Barbara Fernandes Cordeiro, Sara Heloisa da Silva, Rafaela Miranda Pessoa, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Valérie Gagnaire, Martine Deplanche, Bruna Savassi, Alessandra Figueiroa, Emiliano Rosa Oliveira, Caio César Fonseca, Maria Izabel Alves Queiroz, Núbia Morais Rodrigues, Sávio Henrique de Cicco Sandes, Álvaro Cantini Nunes, Luisa Lemos, Juliana de Lima Alves, Ana Maria Caetano Faria, Ênio Ferreira, Yves Le Loir, Gwénaël Jan, Vasco Azevedo

Published Nov 5, 2019

Keywords: mucositis, probiotic, surface protein, immunomodulation, inflammation

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A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Correction: Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of p18 through claudin7 Correction

Correction: Dual-targeting nanoparticles with excellent gene transfection efficiency for gene therapy of peritoneal metastasis of colorectal cancer Correction

Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation Research Paper

p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis Research Paper

An innovative diagnostic strategy for the detection of rare molecular targets to select cancer patients for tumor-agnostic treatments Research Paper

Analog-sensitive cell line identifies cellular substrates of CDK9 Research Paper

Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a Research Paper

Survival correlation of immune response in human cancers Research Paper

Correction: Gene function analysis and underlying mechanism of esophagus cancer based on microarray gene expression profiling Correction

Mesangiogenic progenitor cells are forced toward the angiogenic fate, in multiple myeloma Research Paper

NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis Research Paper

Retraction: Relationship between rs1801157 polymorphism in stromal cell-derived factor gene and systemic lupus erythematosus risk Retraction

Lactate induces PD-L1 in HRAS^G12V-positive oropharyngeal squamous cell carcinoma Research Paper

The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer Review

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

The multifaceted anti-cancer effects of BRAF-inhibitors Review

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Correction: Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of p18 through claudin7 Correction

Correction: Dual-targeting nanoparticles with excellent gene transfection efficiency for gene therapy of peritoneal metastasis of colorectal cancer Correction

Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation Research Paper

p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis Research Paper

An innovative diagnostic strategy for the detection of rare molecular targets to select cancer patients for tumor-agnostic treatments Research Paper

Analog-sensitive cell line identifies cellular substrates of CDK9 Research Paper

Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a Research Paper

Survival correlation of immune response in human cancers Research Paper

Correction: Gene function analysis and underlying mechanism of esophagus cancer based on microarray gene expression profiling Correction

Mesangiogenic progenitor cells are forced toward the angiogenic fate, in multiple myeloma Research Paper

NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis Research Paper

Retraction: Relationship between rs1801157 polymorphism in stromal cell-derived factor gene and systemic lupus erythematosus risk Retraction

Lactate induces PD-L1 in HRASG12V-positive oropharyngeal squamous cell carcinoma Research Paper

The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer Review

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

The multifaceted anti-cancer effects of BRAF-inhibitors Review

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Lactate induces PD-L1 in HRAS^G12V-positive oropharyngeal squamous cell carcinoma Research Paper