The Oncosearch | Oncotarget

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Beatriz Ballester, Javier Milara, Julio Cortijo

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1306-1320

Keywords: pirfenidone, idiopathic pulmonary fibrosis, MUC1, transforming growth factor beta-1, fibroblasts

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Indu Kohaar, Qiyuan Li, Yongmei Chen, Lakshmi Ravindranath, Denise Young, Amina Ali, Isabell A. Sesterhenn, Inger L. Rosner, Jennifer Cullen, Shiv Srivastava, Matthew Freedman, Gyorgy Petrovics

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1321-1333

Keywords: prostate cancer, TMPRSS2-ERG, molecular subtype, ERG fusion, SNP

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Vaishali Kapoor, Andrea Collins, Kaylan Griffith, Subhajit Ghosh, Nathan Wong, Xiaowei Wang, Grant A. Challen, Joseph Krambs, Dan Link, Dennis E. Hallahan, Dinesh Thotala

Published Apr 13, 2020 · Vol. 11, No. 19 · pp. 1681-1690

Keywords: radiation, lymphopenia, mass cytometry RNA sequencing

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

David J. Lamb, Aleksander Rust, Albin Rudisch, Tobias Glüxam, Nathalie Harrer, Herwig Machat, Ingrid Christ, Florian Colbatzky, Andreas Wernitznig, Annika Osswald, Wolfgang Sommergruber

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1257-1272

Keywords: SYK inhibitor, breast carcinoma, 3D culture, murine mammary gland, proliferation

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Natalia V. Eremina, Vasily I. Kazey, Sergey V. Mishugin, Roman V. Leonenkov, Dmitry Y. Pushkar, Vadim L. Mett, Andrei V. Gudkov

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1273-1288

Keywords: prostate cancer, immunotherapy, mobilan, adenoviral vector, intratumor injection

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Bhagyashri Kulkarni, Piyush Gondaliya, Prathibha Kirave, Rakesh Rawal, Alok Jain, Rachana Garg, Kiran Kalia

Published Apr 2, 2020 · Vol. 11, No. 20 · pp. 1832-1845

Keywords: chemoresistance, miRNA30a-5p, exosomes, oral cancer, autophagy

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Moran Mazuz, Amir Tiroler, Lilach Moyal, Emmilia Hodak, Stalin Nadarajan, Ajjampura C. Vinayaka, Batia Gorovitz-Haris, Ido Lubin, Avi Drori, Guy Drori, Owen Van Cauwenberghe, Adi Faigenboim, Dvora Namdar, Iris Amitay-Laish, Hinanit Koltai

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1141-1156

Keywords: cutaneous T-cell lymphoma, cannabis, cannabinoids, peripheral blood lymphocytes, CTCL cell lines

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Yetirajam Rajesh, Angana Biswas, Payel Banik, Ipsita Pal, Subhayan Das, Sachin A. Borkar, Hardik Sardana, Abhijit Saha, Swadesh K. Das, Luni Emdad, Paul B. Fisher, Mahitosh Mandal

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1097-1108

Keywords: HSPB1, RNAseq, Fli-1, radioresistant GBM, temozolomide resistant GBM

The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma Research Paper

Antonio Herrera-Merchan, Marta Cuadros, Maria Isabel Rodriguez, Sandra Rodriguez, Raul Torres, Marcos Estecio, Isabel F. Coira, Claudia Loidi, Monica Saiz, Pedro Carmona-Saez, Pedro P. Medina

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1172-1185

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Prathibha Kirave, Piyush Gondaliya, Bhagyashri Kulkarni, Rakesh Rawal, Rachana Garg, Alok Jain, Kiran Kalia

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1157-1171

Keywords: cisplatin chemoresistance, miRNA155, exosomes, oral cancer, apoptosis

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

John M. Idso, Shunhua Lao, Nathan J. Schloemer, Jeffrey Knipstein, Robert Burns, Monica S. Thakar, Subramaniam Malarkannan

Published Mar 25, 2020 · Vol. 11, No. 20 · pp. 1799-1815

Keywords: NK cells, histone deacetylase inhibitor, Ewing sarcoma, rhabdomyosarcoma, immunotherapy

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Souhila Abdelfettah, Gaylor Boulay, Marion Dubuissez, Nathalie Spruyt, Sara P. Garcia, Shruthi Rengarajan, Ingrid Loison, Xavier Leroy, Miguel N. Rivera, Dominique Leprince

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1051-1074

Keywords: hPCL3S, PHF19, PRC2, β-catenin, prostate cancer

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Caroline Dafflon, Swann Gaulis, Louise Barys, Karen Kapur, Vanessa Cornacchione, Lina Schukur, Sebastian Bergling, Elisabetta Traggiai, Selina Jansky, Leon Hellmann, Barbara Schacher Engstler, Grainne Kerr, Antoine de Weck, David A. Ruddy, Ulrike Naumann, Frédéric Stauffer, Christoph Gaul, Ying Lin, Eric Billy, Andreas Weiss, Francesco Hofmann, Moriko Ito, Ralph Tiedt

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 956-968

Keywords: DOT1L, multiple myeloma, epigenetics, histone methylation, unfolded protein response

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Fiamma Buttitta, Lara Felicioni, Alessia Di Lorito, Alessio Cortellini, Luciana Irtelli, Davide Brocco, Pietro Di Marino, Donatella Traisci, Nicola D’Ostilio, Alessandra Di Paolo, Francesco Malorgio, Pasquale Assalone, Sonia Di Felice, Francesca Fabbri, Giovanni Cianci, Michele De Tursi, Antonio Marchetti

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 982-991

Keywords: epidermal growth factor receptor (EGFR), tyrosine-kinase Inhibitors, circulating tumor-DNA (ct-DNA), massive parallel sequencing (MPS), resistance-inducing mutation

Acute promyelocytic leukemia (APL): a review of the literature Review

Joaquin J. Jimenez, Ravinder S. Chale, Andrea C. Abad, Andrew V. Schally

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 992-1003

Keywords: promyelocytic leukemia, arsenic trioxide, retinoic acid, resistance

DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues Research Paper

Cristina Gallego-Fabrega, Natalia Cullell, Carolina Soriano-Tárraga, Caty Carrera, Nuria P. Torres-Aguila, Elena Muiño, Jara Cárcel-Márquez, Manuel Castro de Moura, Alba Fernández-Sanlés, Manel Esteller, Roberto Elosua, Jordi Jiménez-Conde, Jaume Roquer, Joan Montaner, Jerzy Krupinski, Israel Fernandez-Cadenas

Published Mar 10, 2020 · Vol. 11, No. 10 · pp. 905-912

Keywords: atherosclerotic plaque, epigenetics, DNA methylation, matrix metalloproteinases

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Ajay Kale, Afaf Aldahish, Girish Shah

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 858-874

Keywords: calcitonin receptor, T-antigen, tumor growth, PTEN, prostate cancer

The transcription factor CUX1 negatively regulates invasion in castrate resistant prostate cancer Research Paper

Emma R. Dorris, Amanda O’Neill, Ann Treacy, Helmut Klocker, Omri Teltsh, Elaine Kay, R. William Watson

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 846-857

Keywords: castration-resistant prostatic cancer, neoplasm invasiveness, androgen-independent prostatic cancer, recurrence

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Stefanie Schlager, Carina Salomon, Sabine Olt, Christoph Albrecht, Anja Ebert, Oliver Bergner, Johannes Wachter, Francesca Trapani, Daniel Gerlach, Tilman Voss, Anna Traunbauer, Julian Jude, Matthias Hinterndorfer, Martina Minnich, Norbert Schweifer, Sophia M. Blake, Vittoria Zinzalla, Barbara Drobits, Darryl B. McConnell, Norbert Kraut, Mark Pearson, Johannes Zuber, Manfred Koegl

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 875-890

Keywords: BCL6, DLBCL, lymphoma, inducible CRISPR/Cas9, in vivo xenograft

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Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma Research Paper

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Acute promyelocytic leukemia (APL): a review of the literature Review

DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues Research Paper

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

The transcription factor CUX1 negatively regulates invasion in castrate resistant prostate cancer Research Paper

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma Research Paper

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Acute promyelocytic leukemia (APL): a review of the literature Review

DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues Research Paper

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

The transcription factor CUX1 negatively regulates invasion in castrate resistant prostate cancer Research Paper

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper